| Sep 4, 2024 (view filing) | Sep 3 | 1 day | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.50K | $50.59 | −$75.9K | −3.5%41.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 5, 2024 (view filing) | Sep 3 | 2 days | White William RichardDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.96K | $49.65 | −$97.2K | −100.0%0 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 18, 2024 (view filing) | Sep 16 | 2 days | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.50K | $47.41 | −$71.1K | −3.6%40.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 3, 2024 (view filing) | Oct 1 | 2 days | White William RichardDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −201 | $51.31 | −$10.3K | −100.0%0 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 5, 2024 (view filing) | Nov 1-4 | 4 days | White William RichardDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.34K | $58.27 | −$427.5K | −100.0%0 after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 19, 2024 (view filing) | Nov 15 | 4 days | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −9.16K | $59.64 | −$546.2K | −18.5%40.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 26, 2024 (view filing) | Nov 25 | 1 day | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −14.2K | $65.46 | −$928.4K | −26.0%40.4K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 4, 2024 (view filing) | Dec 2 | 2 days | White William RichardDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.96K | $64.63 | −$126.5K | −100.0%0 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 18, 2024 (view filing) | Dec 16 | 2 days | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.8K | $66.01 | −$844.3K | −15.1%72.1K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 26, 2024 (view filing) | Dec 23 | 3 days | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −19.8K | $63.14 | −$1.25M | −21.6%72.1K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 2, 2025 (view filing) | Dec 30, 2024 | 3 days | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.0K | $61.95 | −$806.1K | −15.3%72.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 6, 2025 (view filing) | Jan 2 | 4 days | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.50K | $62.75 | −$470.6K | −34.8%14.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 4, 2025 (view filing) | Feb 3 | 1 day | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.50K | $55.55 | −$416.6K | −34.8%14.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 20, 2025 (view filing) | Feb 18 | 2 days | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.57K | $54.58 | −$304.2K | −3.5%154.8K after | |
| Feb 20, 2025 (view filing) | Feb 18 | 2 days | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.14K | $54.58 | −$171.2K | −4.3%69.5K after | |
| Feb 20, 2025 (view filing) | Feb 18 | 2 days | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.61K | $54.58 | −$87.9K | −3.8%40.6K after | |
| Feb 20, 2025 (view filing) | Feb 18 | 2 days | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.64K | $54.58 | −$89.4K | −2.3%68.5K after | |
| Feb 20, 2025 (view filing) | Feb 18 | 2 days | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.16K | $54.58 | −$63.4K | −3.0%37.6K after | |
| Feb 20, 2025 (view filing) | Feb 18 | 2 days | Stephenson PamelaChief Commercial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.14K | $54.58 | −$171.2K | −4.3%69.5K after | |
| Mar 12, 2025 (view filing) | Mar 10-12 | 2 days | Ashiya MonaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −312.4K | $54.31 | −$17.0M | −61.7%194.2K after | 15 lotsThis row combines 15 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 12, 2025 (view filing)9:34 PM ET | Mar 10-12 | 2 days | OrbiMed Advisors LLC and 3 othersDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −312.4K | $54.31 | −$17.0M | −61.7%194.2K after | 15 lotsThis row combines 15 trades of the same kind from one filing. The price is the value-weighted average.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Mar 21, 2025 (view filing) | Mar 19-21 | 2 days | Ashiya MonaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.4K | $54.02 | −$2.83M | −21.9%187.3K after | 9 lotsThis row combines 9 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 21, 2025 (view filing)8:00 PM ET | Mar 19-21 | 2 days | OrbiMed Advisors LLC and 3 othersDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.4K | $54.02 | −$2.83M | −21.9%187.3K after | 9 lotsThis row combines 9 trades of the same kind from one filing. The price is the value-weighted average.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| Mar 26, 2025 (view filing) | Mar 24 | 2 days | Ashiya MonaDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.74K | $54.11 | −$310.5K | −3.0%186.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 26, 2025 (view filing)7:00 PM ET | Mar 24 | 2 days | OrbiMed Advisors LLC and 3 othersDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.74K | $54.11 | −$310.5K | −3.0%186.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.Duplicate filingThe same trade also appears in an earlier filing, for example when the same people file twice or a fund and its partners each report it. Rankings and totals count only the earliest copy. |
| May 6, 2025 (view filing) | May 2 | 4 days | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.10K | $50.17 | −$105.4K | −3.1%66.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 22, 2025 (view filing) | May 20 | 2 days | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.68K | $50.04 | −$334.1K | −10.1%59.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 9, 2025 (view filing) | Jun 6 | 3 days | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.00K | $50.00 | −$149.8K | −5.0%56.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 18, 2025 (view filing) | Jun 16 | 2 days | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $52.26 | −$104.5K | −2.9%67.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 8, 2025 (view filing) | Jul 3 | 5 days | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.20K | $55.09 | −$286.5K | −3.1%161.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 11, 2025 (view filing) | Jul 9 | 2 days | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −34.8K | $55.33 | −$1.93M | −17.7%161.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 14, 2025 (view filing) | Jul 10 | 4 days | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.00K | $57.50 | −$115.0K | −3.0%65.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 18, 2025 (view filing) | Jul 17 | 1 day | Franchi Jean M.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.03K | $59.00 | −$119.8K | −3.1%63.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 22, 2025 (view filing) | Jul 18 | 4 days | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −664 | $61.13 | −$40.6K | −0.1%676.8K after | |
| Jul 25, 2025 (view filing) | Jul 23-24 | 2 days | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −42.9K | $61.03 | −$2.62M | −6.3%634.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 1, 2025 (view filing) | Jul 30 | 2 days | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.49K | $61.04 | −$518.4K | −1.3%625.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 7, 2025 (view filing) | Aug 5 | 2 days | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −395 | $60.95 | −$24.1K | −0.1%625.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 15, 2025 (view filing) | Aug 13-14 | 2 days | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −32.2K | $61.11 | −$1.97M | −5.1%592.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 26, 2025 (view filing) | Aug 22 | 4 days | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.29K | $61.03 | −$139.6K | −0.4%590.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 9, 2025 (view filing) | Oct 7-8 | 2 days | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −90.0K | $70.14 | −$6.31M | −15.2%500.6K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 17, 2025 (view filing) | Oct 15-17 | 2 days | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −93.6K | $85.97 | −$8.05M | −19.5%385.5K after | 17 lotsThis row combines 17 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 24, 2025 (view filing)4:01 PM ET | Oct 22 | 2 days | Blavatnik Len and 3 others10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −744.0K | $80.47 | −$59.9M | −20.9%2.81M after | |
| Nov 13, 2025 (view filing) | Nov 11 | 2 days | Yu Jonathan Yen-WenChief Operating Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −30.0K | $84.70 | −$2.54M | −42.5%40.6K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 15, 2025 (view filing) | Dec 11 | 4 days | Quisel John DChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −40.0K | $93.05 | −$3.72M | −18.9%171.8K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 16, 2025 (view filing) | Dec 12-16 | 4 days | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −177.1K | $91.55 | −$16.2M | −92.6%14.2K after | 18 lotsThis row combines 18 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 16, 2025 (view filing) | Dec 15 | 1 day | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.00K | $91.87 | −$643.1K | −100.0%0 after | |
| Dec 16, 2025 (view filing) | Dec 15 | 1 day | Savage William JacobChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.1K | $91.22 | −$1.19M | −14.7%75.7K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Dec 18, 2025 (view filing) | Dec 17 | 1 day | Bitterman KevinDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −754 | $91.47 | −$69.0K | −5.1%14.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 5, 2026 (view filing) | Jan 2 | 3 days | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.50K | $78.68 | −$511.4K | −14.7%37.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jan 21, 2026 (view filing) | Jan 20 | 1 day | Khara RahulChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.00K | $69.74 | −$69.7K | −2.6%37.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
