| Mar 5, 2026 (view filing) | Mar 3-4 | 2 days | Loscalzo JosephDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.03K | $80.27 | −$82.8K | −2.8%36.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 11, 2026 (view filing) | Mar 10 | 1 day | Jenne KyleEVP, Chf GL Pdt Str Ofcr | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −37.3K | $75.85 | −$2.83M | −76.1%11.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 11, 2026 (view filing) | Mar 9-10 | 2 days | Monia Brett PChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −160.8K | $75.35 | −$12.1M | −39.9%242.7K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 11, 2026 (view filing) | Mar 9 | 2 days | O'Neil Patrick R.EVP CLO & General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.1K | $75.25 | −$763.6K | −14.0%62.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 18, 2026 (view filing) | Mar 16-17 | 2 days | Hougen Elizabeth LEVP, Finance & CFO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −225.2K | $72.43 | −$16.3M | −73.2%82.7K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 23, 2026 (view filing) | Mar 19 | 4 days | Schneider EugeneEVP, Chf Clinical Develop Ofcr | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.81K | $70.97 | −$412.5K | −8.3%63.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 2, 2026 (view filing) | Apr 2 | Same day | Devers Shannon L.EVP, Chief Human Resources Ofc | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.19K | $74.05 | −$458.6K | −27.5%16.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 2, 2026 (view filing) | Apr 1 | 1 day | Klein Joseph IIIDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −22.3K | $75.54 | −$1.69M | −67.0%11.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 17, 2026 (view filing) | Apr 16 | 1 day | Baroldi JosephEVP, Chief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.62K | $74.56 | −$419.0K | −10.8%46.5K after | |
| Apr 17, 2026 (view filing) | Apr 16 | 1 day | Birchler BrianEVP, Corp and Development Ops | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −973 | $75.04 | −$73.0K | −1.4%67.5K after | |
| Apr 17, 2026 (view filing) | Apr 16 | 1 day | Jenne KyleEVP, Chf GL Pdt Str Ofcr | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.90K | $75.17 | −$368.5K | −17.1%23.7K after | |
| Apr 17, 2026 (view filing) | Apr 15 | 2 days | Parshall B LynneDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $76.27 | −$381.4K | −8.9%51.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 30, 2026 (view filing) | Apr 28 | 2 days | Baroldi JosephEVP, Chief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.63K | $71.79 | −$116.7K | −3.5%44.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 5, 2026 (view filing) | May 1 | 4 days | Klein Joseph IIIDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.1K | $73.51 | −$743.2K | −47.9%11.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 6, 2026 (view filing) | May 4 | 2 days | Loscalzo JosephDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −77.3K | $75.06 | −$5.80M | −68.0%36.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 15, 2026 (view filing) | May 13-14 | 2 days | Monia Brett PChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.54K | $78.49 | −$356.0K | −1.8%242.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 3, 2026 (view filing) | Jun 1 | 2 days | Berthelsen Spencer RDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.00K | $75.67 | −$605.4K | −4.9%156.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 16, 2026 (view filing) | Jun 15 | 1 day | Berthelsen Spencer RDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.00K | $73.49 | −$587.9K | −4.9%156.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 16, 2026 (view filing) | Jun 12 | 4 days | Kordasiewicz Holly B.EVP, Chief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −60.8K | $73.40 | −$4.47M | −73.0%22.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 26, 2026 (view filing) | Jun 25 | 1 day | Swayze EricEVP Research | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.6K | $79.18 | −$839.5K | −32.8%21.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 26, 2026 (view filing) | Jun 24-26 | 2 days | Monia Brett PChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −85.6K | $79.70 | −$6.83M | −25.9%245.6K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 30, 2026 (view filing) | Jun 26 | 4 days | Schneider EugeneEVP, Chf Clinical Develop Ofcr | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −26.0K | $81.05 | −$2.11M | −25.2%77.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 30, 2026 (view filing) | Jun 26 | 4 days | O'Neil Patrick R.EVP CLO & General Counsel | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.07K | $80.00 | −$245.5K | −4.8%61.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 30, 2026 (view filing) | Jun 26 | 4 days | Baroldi JosephEVP, Chief Business Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.63K | $80.16 | −$451.7K | −54.7%4.67K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 6, 2026 (view filing)6:49 PM ET | Jul 1 | 5 days | Klein Joseph IIIDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −11.5K | $79.04 | −$910.4K | −51.1%11.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 9, 2026 (view filing)6:07 PM ET | Jul 7 | 2 days | Kordasiewicz Holly B.EVP, Chief Development Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −362 | $84.30 | −$30.5K | −1.6%22.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 9, 2026 (view filing)6:07 PM ET | Jul 7 | 2 days | Diaz Allene M.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.1K | $85.42 | −$863.6K | −72.6%3.81K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 9, 2026 (view filing)7:26 PM ET | Jul 7 | 2 days | Bennett C FrankEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.54K | $83.58 | −$462.7K | −6.9%75.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 9, 2026 (view filing)7:26 PM ET | Jul 7 | 2 days | Bennett C FrankEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.0K | $85.46 | −$1.28M | −100.0%0 after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 31, 2026 (view filing)4:42 PM ET | Jul 30-31 | 1 day | Hayden Michael RDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +20.0K | $52.94 | +$1.06M | +500.0%24.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
