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Fractyl Health, Inc.

GUTS
Exchange
Nasdaq
Industry
Surgical & Medical Instruments & Apparatus
SEC CIK
0001572616

In the last 90 days, Fractyl Health, Inc. insiders filed 1 open-market purchase and 0 sales; 77 institutions reported holding it in 13F filings for Q2 2026, worth $56.2M in total; Maverick Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Fractyl Health, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
97
+25 vs. Q3 2025
Shares held
112.4M
+20.9M (+22.9%) vs. Q3 2025
Total value
$247.3M
+$101.9M (+70.1%) vs. Q3 2025
New holders
33
32 more added
Sold out
8
18 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GUTS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 97 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 42 institutionsQ2 2024: 44 institutionsQ3 2024: 61 institutionsQ4 2024: 65 institutionsQ1 2025: 65 institutionsQ2 2025: 62 institutionsQ3 2025: 74 institutionsQ4 2025: 97 institutionsQ1 2026: 83 institutionsQ2 2026: 77 institutions
Value heldQ4 2025: $247.3M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $185.3MQ2 2024: $116.9MQ3 2024: $65.4MQ4 2024: $53.4MQ1 2025: $29.7MQ2 2025: $44.9MQ3 2025: $145.4MQ4 2025: $247.3MQ1 2026: $33.0MQ2 2026: $56.2M
Institutions holding GUTS and their total value by quarter
QuarterHoldersValue
Q2 202677$56.2M
Q1 202683$33.0M
Q4 202597$247.3M
Q3 202574$145.4M
Q2 202562$44.9M
Q1 202565$29.7M
Q4 202465$53.4M
Q3 202461$65.4M
Q2 202444$116.9M
Q1 202442$185.3M
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Fractyl Health, Inc.; share changes are against Q3 2025.

Institutions holding GUTS in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Optiver Holding B.V.14$310.00%00.0%Unchanged
SBI Securities Co., Ltd.120$2640.00%00.0%Unchanged
Allworth Financial LP149$3280.00%+149New
Jones Financial Companies LLLP500$1.10K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA802$1.76K0.00%−113−12.3%Reduced
JPMorgan Chase & Co934$2.06K0.00%−49,810−98.2%Reduced
CIBC Private Wealth Group, LLC1,200$2.64K0.00%+1,200New
Sound Income Strategies, LLC1,971$3.77K0.00%+971+97.1%Added
St. Johns Investment Management Company, LLC1,980$4.36K0.00%00.0%Unchanged
Millington Financial Advisors, LLC12,562$5.21K0.00%+12,562New
Triumph Capital Management3,000$6.60K0.00%+3,000New
Larson Financial Group LLC5,953$13.1K0.00%+5,953New
Bank of New York Mellon Corp10,079$22.2K0.00%+10,079New
LPL Financial LLC10,425$22.9K0.00%00.0%Unchanged
Victory Capital Management Inc13,059$28.7K0.00%+13,059New
R Squared Ltd13,979$30.8K0.01%+3,356+31.6%Added
Tower Research Capital LLC (TRC)14,768$32.5K0.00%+9,559+183.5%Added
Raymond James Financial Inc15,074$33.2K0.00%+2,374+18.7%Added
Parkside Financial Bank & Trust16,304$35.9K0.00%00.0%Unchanged
Bronte Capital Management Pty Ltd.16,905$37.2K0.00%+16,905New
Centiva Capital, LP17,419$38.3K0.00%−31,921−64.7%Reduced
Creative Planning17,514$38.5K0.00%+17,514New
Scientech Research LLC18,006$39.6K0.02%−12,563−41.1%Reduced
Jump Financial, LLC26,000$57.2K0.00%+26,000New
Chicago Partners Investment Group LLC31,000$64.8K0.00%00.0%Unchanged
Citigroup Inc35,076$77.2K0.00%+34,859+16,064.1%Added
Lighthouse Investment Partners, LLC36,300$79.9K0.00%+36,300New
Commonwealth Equity Services, LLC38,700$85.1K0.00%+38,700New
FNY Investment Advisers, LLC48,650$107.0K0.03%+28,650+143.3%Added
Susquehanna Portfolio Strategies, LLC49,137$108.1K0.00%+49,137New
Schonfeld Strategic Advisors LLC50,204$110.4K0.00%+50,204New
HighTower Advisors, LLC51,442$113.2K0.00%00.0%Unchanged
XTX Topco Ltd51,932$114.3K0.00%+5,885+12.8%Added
Bridgeway Capital Management, LLC54,500$119.9K0.00%+9,000+19.8%Added
Verition Fund Management LLC54,910$120.8K0.00%+54,910New
Balyasny Asset Management LLC60,219$132.5K0.00%+60,219New
Cambridge Investment Research Advisors, Inc.64,000$141.0K0.00%+64,000New
Conservest Capital Advisors, Inc.64,118$141.1K0.01%00.0%Unchanged
Virtu Financial LLC69,427$153.0K0.01%+69,427New
Advisor Group Holdings, Inc.75,476$166.0K0.00%−1,269−1.7%Reduced
Prelude Capital Management, LLC80,597$177.3K0.01%+45,843+131.9%Added
Qube Research & Technologies Ltd117,631$258.8K0.00%+94,736+413.8%Added
Quantbot Technologies LP120,434$265.0K0.01%+120,434New
Shay Capital LLC136,568$300.4K0.05%−148,634−52.1%Reduced
Squarepoint Ops LLC147,659$324.9K0.00%+147,659New
Cerity Partners LLC163,500$359.7K0.00%+149,934+1,105.2%Added
Hudson Bay Capital Management LP171,816$378.0K0.00%+171,816New
ExodusPoint Capital Management, LP178,024$391.7K0.00%+178,024New
Omers Administration Corp179,300$394.5K0.00%+179,300New
Gsa Capital Partners LLP189,176$416.0K0.04%+10,153+5.7%Added
PEAK6 LLC200,000$440.0K0.01%−50,000−20.0%Reduced
Northern Trust Corp215,877$474.9K0.00%+201,237+1,374.6%Added
Citadel Advisors LLC228,985$503.8K0.00%−1,553,371−87.2%Reduced
Barclays PLC243,294$535.2K0.00%+243,294New
Boothbay Fund Management, LLC275,219$605.5K0.02%−379,981−58.0%Reduced
Quadrature Capital Ltd290,714$639.6K0.01%+277,174+2,047.1%Added
Point72 Asset Management, L.P.365,173$803.4K0.00%−1,822,826−83.3%Reduced
Rosalind Advisors, Inc.385,731$848.6K0.33%−4,614,269−92.3%Reduced
Soleus Capital Management, L.P.400,000$880.0K0.04%−2,100,000−84.0%Reduced
Brevan Howard Capital Management LP464,738$1.05M0.02%+464,738New
Burkehill Global Management, LP500,000$1.10M0.07%00.0%Unchanged
Diametric Capital, LP503,409$1.11M0.30%+377,780+300.7%Added
State Street Corp512,700$1.13M0.00%+471,900+1,156.6%Added
Walleye Capital LLC592,125$1.30M0.01%+592,125New
Morgan Stanley656,482$1.44M0.00%+226,251+52.6%Added
Susquehanna International Group, LLP799,457$1.76M0.00%+799,457New
CM Management, LLC800,000$1.76M1.48%+200,000+33.3%Added
Massachusetts Financial Services Co852,344$1.88M0.00%−73,505−7.9%Reduced
Logos Global Management LP1,100,000$2.42M0.16%+600,000+120.0%Added
Ikarian Capital, LLC1,100,000$2.42M0.31%−700,000−38.9%Reduced
UBS Group AG1,113,982$2.45M0.00%+361,386+48.0%Added
Newtyn Management, LLC1,134,021$2.49M0.26%+1,134,021New
Bank of America Corp1,192,236$2.62M0.00%+1,103,602+1,245.1%Added
Geode Capital Management, LLC1,263,855$2.78M0.00%+968,907+328.5%Added
Two Sigma Advisers, LP1,298,700$2.86M0.01%+1,298,700New
D. E. Shaw & Co., Inc.1,442,745$3.17M0.00%+1,148,455+390.2%Added
Two Sigma Investments, LP1,840,136$4.05M0.01%+1,840,136New
M28 Capital Management LP1,856,117$4.08M2.97%00.0%Unchanged
Millennium Management LLC1,861,418$4.10M0.00%+1,453,751+356.6%Added
Jane Street Group, LLC1,862,600$4.10M0.00%+1,862,600New
Renaissance Technologies LLC1,863,051$4.10M0.01%+1,086,351+139.9%Added
Atom Investors LP1,883,018$4.14M0.33%+1,883,018New
BlackRock, Inc.2,083,318$4.58M0.00%+1,323,323+174.1%Added
Pale Fire Capital SE3,209,942$7.06M0.91%+3,209,942New
Goldman Sachs Group Inc3,425,197$7.54M0.00%+2,934,749+598.4%Added
Alyeska Investment Group, L.P.3,809,523$8.38M0.02%−1,838,848−32.6%Reduced
Maverick Capital LtdSuperinvestorMaverick Capital4,248,492$9.35M0.10%00.0%Unchanged
HCC Manager LLC4,673,870$10.3M100.00%−10.0%Reduced
Deer Management Co. LLC4,770,901$10.5M1.02%00.0%Unchanged
General Catalyst Group Management, LLC4,884,193$10.7M4.85%00.0%Unchanged
Catalio Capital Management, LP5,491,866$12.1M2.14%+277,630+5.3%Added
Woodline Partners LP5,506,771$12.1M0.05%+2370.0%Added
Marshall Wace, LLP5,926,745$13.0M0.01%+4,156,969+234.9%Added
Vanguard Group Inc6,028,179$13.3M0.00%+4,107,032+213.8%Added
683 Capital Management, LLC6,047,620$13.3M1.11%+1,397,620+30.1%Added
Silverarc Capital Management, LLC9,840,041$21.6M3.13%−759,959−7.2%Reduced
Nantahala Capital Management, LLC10,846,440$23.9M1.42%−1,290,477−10.6%Reduced
Alphabet Inc.0$00.00%−662,584−100.0%Sold out
HRT Financial LP0$00.00%−614,792−100.0%Sold out
Arrowpoint Investment Partners (Singapore) Pte. Ltd.0$00.00%−35,000−100.0%Sold out