Monte Rosa Therapeutics, Inc.
GLUE- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001826457
In the last 90 days, Monte Rosa Therapeutics, Inc. insiders filed 0 open-market purchases and 4 sales; 192 institutions reported holding it in 13F filings for Q2 2026, worth $2.24B in total; Duquesne Family Office is the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Monte Rosa Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 161
- +33 vs. Q3 2025
- Shares held
- 64.5M
- +4.44M (+7.4%) vs. Q3 2025
- Total value
- $1.01B
- +$566.1M (+127.3%) vs. Q3 2025
- New holders
- 49
- 54 more added
- Sold out
- 16
- 39 more reduced
1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting GLUE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 192 | $2.24B |
| Q1 2026 | 191 | $1.43B |
| Q4 2025 | 161 | $1.01B |
| Q3 2025 | 129 | $444.9M |
| Q2 2025 | 116 | $280.6M |
| Q1 2025 | 106 | $276.2M |
| Q4 2024 | 105 | $423.3M |
| Q3 2024 | 81 | $263.7M |
| Q2 2024 | 75 | $171.7M |
| Q1 2024 | 68 | $281.3M |
| Q4 2023 | 71 | $226.6M |
| Q3 2023 | 71 | $201.4M |
| Q2 2023 | 68 | $272.3M |
| Q1 2023 | 69 | $309.8M |
| Q4 2022 | 66 | $313.8M |
| Q3 2022 | 70 | $328.8M |
| Q2 2022 | 57 | $375.0M |
| Q1 2022 | 52 | $559.9M |
| Q4 2021 | 53 | $742.0M |
| Q3 2021 | 56 | $759.4M |
| Q2 2021 | 48 | $705.1M |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Monte Rosa Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rhumbline Advisers | 61,859 | $969.9K | 0.00% | −2,087−3.3% | Reduced |
| Diadema Partners LP | 62,281 | $976.6K | 0.58% | +62,281 | New |
| Advisory Research Inc | 63,220 | $991.3K | 0.12% | +63,220 | New |
| Alliancebernstein L.P. | 63,480 | $995.4K | 0.00% | 00.0% | Unchanged |
| Rafferty Asset Management, LLC | 67,438 | $1.06M | 0.00% | +67,438 | New |
| Rangeley Capital, LLC | 67,500 | $1.06M | 0.91% | −45,500−40.3% | Reduced |
| Canada Pension Plan Investment Board | 68,100 | $1.07M | 0.00% | +68,100 | New |
| EAM Investors, LLC | 70,037 | $1.10M | 0.12% | +70,037 | New |
| Franklin Resources Inc | 85,231 | $1.34M | 0.00% | +41,811+96.3% | Added |
| D. E. Shaw & Co., Inc. | 85,488 | $1.34M | 0.00% | +35,275+70.3% | Added |
| Casdin Capital, LLC | 86,014 | $1.35M | 0.08% | 00.0% | Unchanged |
| Ieq Capital, LLC | 89,268 | $1.40M | 0.00% | +30,202+51.1% | Added |
| Campbell & CO Investment Adviser LLC | 90,752 | $1.42M | 0.07% | +39,619+77.5% | Added |
| Millennium Management LLC | 103,972 | $1.63M | 0.00% | −340,967−76.6% | Reduced |
| Ameriprise Financial Inc | 122,164 | $1.92M | 0.00% | +122,164 | New |
| UBS Group AG | 123,000 | $1.93M | 0.00% | +50,905+70.6% | Added |
| Barclays PLC | 135,984 | $2.13M | 0.00% | +63,029+86.4% | Added |
| Manufacturers Life Insurance Company, The | 134,674 | $2.15M | 0.00% | +16,291+13.8% | Added |
| Jane Street Group, LLC | 137,049 | $2.15M | 0.00% | −170,000−55.4% | Reduced |
| Atom Investors LP | 137,261 | $2.15M | 0.17% | +137,261 | New |
| Wellington Management Group LLP | 148,057 | $2.32M | 0.00% | −10,467−6.6% | Reduced |
| Trexquant Investment LP | 149,712 | $2.35M | 0.02% | +149,712 | New |
| Bank of New York Mellon Corp | 173,304 | $2.72M | 0.00% | −13,494−7.2% | Reduced |
| Nomura Asset Management International Inc. | 200,000 | $3.14M | 0.00% | +200,000 | New |
| TD Asset Management Inc | 213,464 | $3.35M | 0.00% | +41,386+24.1% | Added |
| ADAR1 Capital Management, LLC | 215,752 | $3.38M | 0.25% | 00.0% | Unchanged |
| Bank of America Corp | 223,571 | $3.51M | 0.00% | −46,072−17.1% | Reduced |
| Acadian Asset Management LLC | 247,855 | $3.88M | 0.01% | +44,305+21.8% | Added |
| Empowered Funds, LLC | 278,077 | $4.36M | 0.07% | +190,627+218.0% | Added |
| Nextech Invest, Ltd. | 279,237 | $4.38M | 0.42% | +279,237 | New |
| Nuveen, LLC | 285,859 | $4.48M | 0.00% | +182,891+177.6% | Added |
| Goldman Sachs Group Inc | 295,878 | $4.64M | 0.00% | +194,734+192.5% | Added |
| Arrowstreet Capital, Limited Partnership | 307,651 | $4.82M | 0.00% | +307,651 | New |
| Invesco Ltd. | 362,213 | $5.68M | 0.00% | +264,315+270.0% | Added |
| Marshall Wace, LLP | 398,890 | $6.25M | 0.01% | −503,944−55.8% | Reduced |
| Charles Schwab Investment Management Inc | 448,714 | $7.04M | 0.00% | +65,446+17.1% | Added |
| Bridgeway Capital Management, LLC | 523,377 | $8.21M | 0.17% | +164,527+45.8% | Added |
| Dimensional Fund Advisors LP | 568,367 | $8.91M | 0.00% | −63,815−10.1% | Reduced |
| Northern Trust Corp | 697,034 | $10.9M | 0.00% | −43,650−5.9% | Reduced |
| Parkwood LLC | 708,000 | $11.1M | 0.94% | 00.0% | Unchanged |
| Alphabet Inc. | 744,948 | $11.7M | 0.45% | −719,067−49.1% | Reduced |
| Vestal Point Capital, LP | 775,000 | $12.2M | 0.45% | −25,000−3.1% | Reduced |
| AQR Capital Management LLC | 785,057 | $12.3M | 0.01% | +67,795+9.5% | Added |
| Morgan Stanley | 805,530 | $12.6M | 0.00% | +160,334+24.9% | Added |
| Braidwell LP | 948,316 | $14.9M | 0.48% | +948,316 | New |
| Silverarc Capital Management, LLC | 1,029,066 | $16.1M | 2.33% | +334,124+48.1% | Added |
| MPM Oncology Impact Management LP | 1,173,376 | $18.4M | 2.11% | +1,173,376 | New |
| Geode Capital Management, LLC | 1,204,844 | $18.9M | 0.00% | +53,278+4.6% | Added |
| FMR LLC | 1,300,096 | $20.4M | 0.00% | −1,512,155−53.8% | Reduced |
| American Century Companies Inc | 1,329,619 | $20.8M | 0.01% | +736,225+124.1% | Added |
| Aisling Capital Management LP | 1,472,331 | $23.1M | 4.82% | 00.0% | Unchanged |
| State Street Corp | 2,107,480 | $33.0M | 0.00% | +1,260,707+148.9% | Added |
| Vanguard Group Inc | 3,246,500 | $50.9M | 0.00% | +257,547+8.6% | Added |
| Suvretta Capital Management, LLC | 3,360,000 | $52.7M | 1.31% | 00.0% | Unchanged |
| BVF Inc | 3,835,886 | $60.1M | 2.02% | −1,824,246−32.2% | Reduced |
| BlackRock, Inc. | 4,181,161 | $65.6M | 0.00% | +366,028+9.6% | Added |
| Baker Bros. Advisors LP | 4,345,736 | $68.1M | 0.40% | −570,359−11.6% | Reduced |
| Versant Venture Management, LLC | 4,382,687 | $68.7M | 45.49% | −1,270,235−22.5% | Reduced |
| TCG Crossover Management, LLC | 4,622,151 | $72.5M | 2.40% | +4,622,151 | New |
| Price T Rowe Associates Inc | 5,118,904 | $80.3M | 0.01% | +481,844+10.4% | Added |
| NEA Management Company, LLC | 7,692,298 | $120.6M | 6.15% | 00.0% | Unchanged |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −408,540−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −395,733−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| JBF Capital, Inc. | 0 | $0 | 0.00% | −148,566−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −147,726−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −90,419−100.0% | Sold out |
| Mackenzie Financial Corp | 0 | $0 | 0.00% | −77,635−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −28,300−100.0% | Sold out |
| Bailard, Inc. | 0 | $0 | 0.00% | −22,500−100.0% | Sold out |
| Scientech Research LLC | 0 | $0 | 0.00% | −16,254−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −12,054−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −11,100−100.0% | Sold out |
| Royce & Associates LP | 0 | $0 | 0.00% | −11,024−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −10,871−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −10,202−100.0% | Sold out |
| Summit Wealth Group LLC | 0 | $0 | 0.00% | −2,002−100.0% | Sold out |
| Point72 Europe (London) LLP | – | – | – | – | Not filed |