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Guardant Health, Inc.

GH
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001576280

In the last 90 days, Guardant Health, Inc. insiders filed 0 open-market purchases and 12 sales; 600 institutions reported holding it in 13F filings for Q2 2026, worth $20.0B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Guardant Health, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
498
+108 vs. Q3 2025
Shares held
131.1M
+8.74M (+7.1%) vs. Q3 2025
Total value
$13.4B
+$5.74B (+75.1%) vs. Q3 2025
New holders
141
156 more added
Sold out
33
149 more reduced

6 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GH on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 498 institutions
Q1 2021: 420 institutionsQ2 2021: 417 institutionsQ3 2021: 375 institutionsQ4 2021: 397 institutionsQ1 2022: 356 institutionsQ2 2022: 333 institutionsQ3 2022: 328 institutionsQ4 2022: 292 institutionsQ1 2023: 280 institutionsQ2 2023: 301 institutionsQ3 2023: 297 institutionsQ4 2023: 295 institutionsQ1 2024: 258 institutionsQ2 2024: 282 institutionsQ3 2024: 271 institutionsQ4 2024: 298 institutionsQ1 2025: 342 institutionsQ2 2025: 366 institutionsQ3 2025: 396 institutionsQ4 2025: 498 institutionsQ1 2026: 486 institutionsQ2 2026: 600 institutions
Value heldQ4 2025: $13.4B
Q1 2021: $13.9BQ2 2021: $11.1BQ3 2021: $11.8BQ4 2021: $9.24BQ1 2022: $6.11BQ2 2022: $3.75BQ3 2022: $5.04BQ4 2022: $2.53BQ1 2023: $2.17BQ2 2023: $3.95BQ3 2023: $3.21BQ4 2023: $2.99BQ1 2024: $2.30BQ2 2024: $3.32BQ3 2024: $2.86BQ4 2024: $3.65BQ1 2025: $5.10BQ2 2025: $6.47BQ3 2025: $7.65BQ4 2025: $13.4BQ1 2026: $12.5BQ2 2026: $20.0B
Institutions holding GH and their total value by quarter
QuarterHoldersValue
Q2 2026600$20.0B
Q1 2026486$12.5B
Q4 2025498$13.4B
Q3 2025396$7.65B
Q2 2025366$6.47B
Q1 2025342$5.10B
Q4 2024298$3.65B
Q3 2024271$2.86B
Q2 2024282$3.32B
Q1 2024258$2.30B
Q4 2023295$2.99B
Q3 2023297$3.21B
Q2 2023301$3.95B
Q1 2023280$2.17B
Q4 2022292$2.53B
Q3 2022328$5.04B
Q2 2022333$3.75B
Q1 2022356$6.11B
Q4 2021397$9.24B
Q3 2021375$11.8B
Q2 2021417$11.1B
Q1 2021420$13.9B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Guardant Health, Inc.; share changes are against Q3 2025.

Institutions holding GH in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
GAMMA Investing LLC808$82.5K0.00%+226+38.8%Added
Flagship Harbor Advisors, LLC809$82.6K0.00%+809New
IFP Advisors, Inc844$86.2K0.00%+217+34.6%Added
Allworth Financial LP893$91.2K0.00%+49+5.8%Added
Bullseye Asset Management LLC1,000$102.0K0.05%+1,000New
HM Payson & Co1,000$102.1K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC1,052$107.5K0.00%−75−6.7%Reduced
IMA Wealth, Inc.1,116$114.0K0.01%00.0%Unchanged
JNBA Financial Advisors1,141$116.5K0.01%00.0%Unchanged
Clearstead Advisors, LLC1,141$116.5K0.00%+1,093+2,277.1%Added
Danske Bank A/S1,200$122.6K0.00%+200+20.0%Added
EverSource Wealth Advisors, LLC1,242$126.9K0.00%+209+20.2%Added
Kemnay Advisory Services Inc.1,424$145.4K0.02%+1,424New
McGuire Capital Advisors Inc1,514$154.6K0.10%+1,514New
Smartleaf Asset Management LLC1,606$161.6K0.01%+510+46.5%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,586$162.0K0.00%+459+40.7%Added
Northwestern Mutual Wealth Management Co1,819$185.8K0.00%−528−22.5%Reduced
NBT Bank N A1,825$186.4K0.01%00.0%Unchanged
Harvest Fund Management Co., Ltd1,864$190.0K0.01%00.0%Unchanged
Kimelman & Baird, LLC1,900$194.1K0.01%00.0%Unchanged
CIBC Private Wealth Group, LLC1,918$195.9K0.00%+16+0.8%Added
SBI Securities Co., Ltd.1,949$199.1K0.01%−135−6.5%Reduced
Forefront Wealth Management Inc.2,000$204.3K0.15%+2,000New
Leonteq Securities AG2,069$211.3K0.01%+41+2.0%Added
Norden Group LLC2,072$211.6K0.02%+2,072New
Aigen Investment Management, LP2,105$215.0K0.05%+2,105New
AlphaGrep UK Ltd2,107$215.2K0.07%+2,107New
TCW Group Inc2,120$216.5K0.00%+2,120New
Argent Trust Co2,136$218.2K0.01%+2,136New
Eastern Bank2,160$220.6K0.00%+139+6.9%Added
Eurizon Capital SGR S.p.A.2,233$224.4K0.00%+2,233New
Capstone Investment Advisors, LLC2,239$228.7K0.00%−35,560−94.1%Reduced
Motley Fool Asset Management LLC2,244$229.2K0.01%+2,244New
Natixis2,250$229.8K0.00%−55,650−96.1%Reduced
Captrust Financial Advisors2,257$230.6K0.00%+2,257New
Abacus Wealth Partners, LLC2,273$232.2K0.02%+2,273New
Skopos Labs, Inc.2,317$234.9K0.01%+2,317New
CWM, LLC2,309$236.0K0.00%+289+14.3%Added
Atria Investments LLC2,357$240.7K0.00%−1,457−38.2%Reduced
Profund Advisors LLC2,359$240.9K0.01%+2,359New
Keel Point, LLC2,409$246.1K0.01%+2,409New
Wealth Enhancement Advisory Services, LLC2,222$249.6K0.00%+2,222New
EntryPoint Capital, LLC2,474$252.7K0.10%+2,474New
Ascent Wealth Partners, LLC2,479$253.2K0.03%+2,479New
Pinnacle Wealth Planning Services, Inc.2,485$253.8K0.03%+2,485New
Mount Yale Investment Advisors, LLC2,501$255.5K0.01%+2,501New
GF Fund Management Co. Ltd.2,541$259.5K0.00%−142−5.3%Reduced
Stephens Inc2,644$270.1K0.00%+2,644New
Quest Partners LLC2,654$271.1K0.02%+2,654New
Resources Investment Advisors, LLC.2,678$273.5K0.00%+2,678New
Tower Research Capital LLC (TRC)2,743$280.2K0.01%+138+5.3%Added
Virtus ETF Advisers LLC2,750$280.9K0.13%+2,750New
OneAscent Financial Services LLC2,835$289.6K0.03%+2,835New
Wealthfront Advisers LLC2,838$289.9K0.00%+2,838New
Global Retirement Partners, LLC2,843$290.4K0.01%+2,681+1,654.9%Added
Green Alpha Advisors, LLC2,860$292.1K0.27%−1,546−35.1%Reduced
Blueshift Asset Management, LLC2,877$293.9K0.08%+2,877New
Bellevue Group AG3,004$306.8K0.01%+1,051+53.8%Added
Wesbanco Bank Inc3,016$308.1K0.01%+3,016New
KBC Group NV3,134$320.0K0.00%00.0%Unchanged
Wulff, Hansen & Co.3,185$325.3K0.27%+3,185New
McGuire Investment Group, LLC3,200$326.8K0.03%+3,200New
Susquehanna International Group, LLP3,306$337.7K0.00%−28,380−89.6%Reduced
NBC Securities, Inc.3,339$341.0K0.03%−115−3.3%Reduced
Alamea Verwaltungs GmbH3,010$343.3K0.23%−1,984−39.7%Reduced
World Equity Group, Inc.3,405$347.8K0.10%+3,405New
Nisa Investment Advisors, LLC3,430$350.3K0.00%−101−2.9%Reduced
RWC Asset Management LLP3,775$385.6K0.02%−2,071−35.4%Reduced
Amalgamated Bank3,818$390.0K0.00%−52−1.3%Reduced
Wealthspire Advisors, LLC3,886$396.9K0.00%+235+6.4%Added
Mendel Money Management3,910$399.4K0.17%−545−12.2%Reduced
Everence Capital Management Inc4,080$417.0K0.02%00.0%Unchanged
Fifth Third Bancorp4,105$419.3K0.00%−85−2.0%Reduced
Perpetual Ltd4,337$443.0K0.01%+4,337New
Mercer Global Advisors Inc4,357$445.0K0.00%+490+12.7%Added
Kestra Private Wealth Services, LLC4,471$456.7K0.01%−50−1.1%Reduced
CIBC Asset Management Inc4,519$461.6K0.00%+583+14.8%Added
Gsa Capital Partners LLP4,528$462.0K0.04%−17,454−79.4%Reduced
Abel Hall, LLC4,533$463.0K0.11%+751+19.9%Added
Inspire Advisors, LLC4,816$491.9K0.05%−6,968−59.1%Reduced
Glenmede Trust Co NA4,853$495.7K0.00%+4,853New
TD Waterhouse Canada Inc.4,856$495.8K0.00%−35−0.7%Reduced
Jag Capital Management, LLC4,960$506.6K0.06%+987+24.8%Added
Amundi5,011$511.8K0.00%+5,011New
Odyssean, LLC5,077$518.6K0.37%+5,077New
Schonfeld Strategic Advisors LLC5,081$519.0K0.00%−16,401−76.3%Reduced
Sanctuary Advisors, LLC5,093$520.2K0.00%−1,197−19.0%Reduced
M&T Bank Corp5,118$523.0K0.00%+5,118New
Paradigm Financial Partners, LLC5,157$526.7K0.05%−10−0.2%Reduced
Swiss Life Asset Management Ltd5,290$540.3K0.00%+63+1.2%Added
Quantinno Capital Management LP5,291$540.4K0.00%+232+4.6%Added
Ethic Inc.5,358$547.3K0.01%+1,503+39.0%Added
Oppenheimer & Co Inc5,362$547.7K0.01%+5,362New
Navellier & Associates Inc5,412$552.8K0.06%−2,342−30.2%Reduced
Yorktown Management & Research Co Inc5,550$566.9K0.45%00.0%Unchanged
Mariner, LLC5,611$572.5K0.00%+1,690+43.1%Added
Headlands Technologies LLC5,629$574.9K0.05%+5,629New
Brinker Capital Investments, LLC5,731$585.4K0.00%+5,731New
Susquehanna Fundamental Investments, LLC5,775$589.9K0.02%00.0%Unchanged
Qsemble Capital Management, LP5,882$600.8K0.05%−4,606−43.9%Reduced