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Gain Therapeutics, Inc.

GANX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001819411

No open-market purchases or sales by Gain Therapeutics, Inc. insiders were filed in the last 90 days; 50 institutions reported holding it in 13F filings for Q2 2026, worth $17.4M in total; Greenlight Capital is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Gain Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
48
+11 vs. Q3 2025
Shares held
8.06M
+3.72M (+85.8%) vs. Q3 2025
Total value
$25.9M
+$18.2M (+237.1%) vs. Q3 2025
New holders
21
15 more added
Sold out
10
3 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GANX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 48 institutions
Q1 2021: 12 institutionsQ2 2021: 14 institutionsQ3 2021: 14 institutionsQ4 2021: 19 institutionsQ1 2022: 16 institutionsQ2 2022: 16 institutionsQ3 2022: 23 institutionsQ4 2022: 21 institutionsQ1 2023: 22 institutionsQ2 2023: 24 institutionsQ3 2023: 24 institutionsQ4 2023: 24 institutionsQ1 2024: 26 institutionsQ2 2024: 28 institutionsQ3 2024: 19 institutionsQ4 2024: 25 institutionsQ1 2025: 33 institutionsQ2 2025: 35 institutionsQ3 2025: 38 institutionsQ4 2025: 48 institutionsQ1 2026: 42 institutionsQ2 2026: 50 institutions
Value heldQ4 2025: $25.9M
Q1 2021: $15.0MQ2 2021: $8.95MQ3 2021: $6.65MQ4 2021: $5.71MQ1 2022: $4.75MQ2 2022: $3.87MQ3 2022: $3.95MQ4 2022: $3.78MQ1 2023: $5.54MQ2 2023: $5.68MQ3 2023: $4.95MQ4 2023: $5.05MQ1 2024: $7.04MQ2 2024: $3.89MQ3 2024: $2.40MQ4 2024: $3.94MQ1 2025: $5.07MQ2 2025: $6.49MQ3 2025: $7.70MQ4 2025: $25.9MQ1 2026: $15.8MQ2 2026: $17.4M
Institutions holding GANX and their total value by quarter
QuarterHoldersValue
Q2 202650$17.4M
Q1 202642$15.8M
Q4 202548$25.9M
Q3 202538$7.70M
Q2 202535$6.49M
Q1 202533$5.07M
Q4 202425$3.94M
Q3 202419$2.40M
Q2 202428$3.89M
Q1 202426$7.04M
Q4 202324$5.05M
Q3 202324$4.95M
Q2 202324$5.68M
Q1 202322$5.54M
Q4 202221$3.78M
Q3 202223$3.95M
Q2 202216$3.87M
Q1 202216$4.75M
Q4 202119$5.71M
Q3 202114$6.65M
Q2 202114$8.95M
Q1 202112$15.0M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Gain Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding GANX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Marshall Wace, LLP1,662,293$5.35M0.01%+1,487,186+849.3%Added
Potomac Capital Management, Inc.1,010,000$3.25M2.72%+1,010,000New
Jones Financial Companies LLLP702,213$2.26M0.00%+25,391+3.8%Added
Susquehanna International Group, LLP684,349$2.20M0.00%+603,914+750.8%Added
Vanguard Group Inc569,901$1.84M0.00%+35,549+6.7%Added
Cambridge Investment Research Advisors, Inc.568,645$1.83M0.00%+250,000+78.5%Added
DME Capital Management, LPSuperinvestorGreenlight Capital566,130$1.82M0.06%00.0%Unchanged
Geode Capital Management, LLC397,942$1.28M0.00%+53,796+15.6%Added
Jane Street Group, LLC242,328$780.3K0.00%+169,878+234.5%Added
BlackRock, Inc.209,579$674.8K0.00%+93,395+80.4%Added
Cresset Asset Management, LLC160,000$515.2K0.00%+160,000New
State Street Corp157,537$507.3K0.00%+66,400+72.9%Added
Morgan Stanley147,591$475.2K0.00%−8,084−5.2%Reduced
LPL Financial LLC106,550$343.1K0.00%+106,550New
Northern Trust Corp102,001$328.4K0.00%+13,602+15.4%Added
UBS Group AG81,121$261.2K0.00%−59,556−42.3%Reduced
Colony Group, LLC77,855$250.7K0.00%+77,855New
HRT Financial LP55,679$179.0K0.00%+35,962+182.4%Added
Group One Trading, L.P.54,159$174.4K0.01%+37,384+222.9%Added
Simplex Trading, LLC47,946$154.4K0.00%+47,946New
Benedict Financial Advisors Inc38,000$122.4K0.03%+3,000+8.6%Added
Omers Administration Corp37,300$120.1K0.00%+37,300New
Prelude Capital Management, LLC35,820$115.3K0.01%00.0%Unchanged
Goldman Sachs Group Inc32,494$104.6K0.00%+32,494New
Point72 Asset Management, L.P.32,480$104.6K0.00%+32,480New
Bridgeway Capital Management, LLC30,004$96.6K0.00%00.0%Unchanged
Lighthouse Investment Partners, LLC23,040$74.2K0.00%+23,040New
Gsa Capital Partners LLP20,472$66.0K0.01%+20,472New
Oliver Luxxe Assets LLC20,250$65.2K0.01%+20,250New
Apollon Wealth Management, LLC19,825$63.8K0.00%+19,825New
Renaissance Technologies LLC17,400$56.0K0.00%−108,700−86.2%Reduced
Wealthspire Advisors, LLC16,900$54.4K0.00%+16,900New
Sandhill Capital Partners LLC15,400$49.6K0.00%00.0%Unchanged
Engineers Gate Manager LP14,617$47.1K0.00%+14,617New
Millennium Management LLC14,002$45.1K0.00%+14,002New
Commonwealth Equity Services, LLC12,685$40.9K0.00%+12,685New
Wealth Enhancement Advisory Services, LLC15,556$39.7K0.00%00.0%Unchanged
Kestra Advisory Services, LLC12,000$38.6K0.00%00.0%Unchanged
Sprott Inc.12,000$38.6K0.00%+12,000New
GWM Advisors LLC10,600$34.1K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)6,859$22.1K0.00%+4,795+232.3%Added
MAI Capital Management4,410$14.2K0.00%00.0%Unchanged
Bank of America Corp3,908$12.6K0.00%+10.0%Added
Wells Fargo & Company2,650$8.53K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA2,381$7.67K0.00%+2,381New
FNY Investment Advisers, LLC2,000$6.00K0.00%+2,000New
State of Wyoming1,438$4.63K0.00%+1,438New
Larson Financial Group LLC10$320.00%+10New
Citadel Advisors LLC0$00.00%−373,558−100.0%Sold out
Virtu Financial LLC0$00.00%−54,008−100.0%Sold out
XTX Topco Ltd0$00.00%−54,202−100.0%Sold out
Kovitz Investment Group Partners, LLC0$00.00%−47,578−100.0%Sold out
Squarepoint Ops LLC0$00.00%−38,537−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−27,323−100.0%Sold out
JPMorgan Chase & Co0$00.00%−26,280−100.0%Sold out
HighTower Advisors, LLC0$00.00%−11,574−100.0%Sold out
Armis Advisers, LLC0$00.00%−10,750−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−3,250−100.0%Sold out
Creekmur Asset Management LLC––––Not filed