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Epizyme, Inc.

EPZMDelisted Aug 12, 2022
Industry
Pharmaceutical Preparations
SEC CIK
0001571498

Epizyme, Inc. was delisted on Aug 12, 2022; its insiders filed their last Form 4 on Aug 16, 2022; 94 institutions reported holding it in 13F filings for Q2 2022, worth $187.0M in total; no superinvestor held it.

13F holders, Q4 2021

Institutional positions in Epizyme, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
132
+17 vs. Q3 2021
Shares held
84.8M
−5.06M (−5.6%) vs. Q3 2021
Total value
$212.1M
−$248.1M (−53.9%) vs. Q3 2021
New holders
37
39 more added
Sold out
20
36 more reduced

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EPZM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 132 institutions
Q1 2021: 140 institutionsQ2 2021: 127 institutionsQ3 2021: 116 institutionsQ4 2021: 132 institutionsQ1 2022: 120 institutionsQ2 2022: 94 institutionsQ3 2022: 1 institutionQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 0 institutionsQ4 2024: 0 institutionsQ1 2025: 0 institutionsQ2 2025: 0 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2021: $212.1M
Q1 2021: $838.5MQ2 2021: $790.2MQ3 2021: $479.9MQ4 2021: $212.1MQ1 2022: $177.5MQ2 2022: $187.0MQ3 2022: $4.00KQ4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $0Q4 2024: $0Q1 2025: $0Q2 2025: $0Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding EPZM and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20250$0
Q1 20250$0
Q4 20240$0
Q3 20240$0
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20221$4.00K
Q2 202294$187.0M
Q1 2022120$177.5M
Q4 2021132$212.1M
Q3 2021116$479.9M
Q2 2021127$790.2M
Q1 2021140$838.5M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Epizyme, Inc.; share changes are against Q3 2021.

Institutions holding EPZM in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Primecap Management Co15,366,477$38.4M0.03%+56,100+0.4%Added
RP Management, LLC9,166,667$22.9M10.46%00.0%Unchanged
BlackRock Inc.7,615,648$19.0M0.00%+71,289+0.9%Added
Vanguard Group Inc5,984,908$15.0M0.00%−1,873,365−23.8%Reduced
Palo Alto Investors LP5,485,213$13.7M0.88%−1,371,300−20.0%Reduced
Rock Springs Capital Management LP3,807,662$9.52M0.22%+213,777+5.9%Added
MPM Oncology Impact Management LP3,425,202$8.56M1.56%−547,628−13.8%Reduced
Goldman Sachs Group Inc3,262,543$8.16M0.00%+2,690,437+470.3%Added
Bank of America Corp2,955,970$7.39M0.00%+2,912,277+6,665.3%Added
Platinum Investment Management Ltd2,822,936$7.06M0.20%+919,043+48.3%Added
Millennium Management LLC1,954,128$4.88M0.01%+1,532,196+363.1%Added
State Street Corp1,840,529$4.60M0.00%−4,187,682−69.5%Reduced
Geode Capital Management, LLC1,658,936$4.15M0.00%−34,581−2.0%Reduced
Two Sigma Investments, LP1,022,627$2.56M0.01%+1,010,627+8,421.9%Added
Northern Trust Corp948,546$2.37M0.00%+12,285+1.3%Added
CIBC Private Wealth Group, LLC882,000$2.21M0.00%−832,500−48.6%Reduced
FMR LLC865,373$2.16M0.00%−934,744−51.9%Reduced
Norges Bank818,853$2.05M0.00%+72,475+9.7%Added
Morgan Stanley788,360$1.97M0.00%−1,920,113−70.9%Reduced
Citadel Advisors LLC776,335$1.94M0.00%+736,685+1,858.0%Added
Frazier Management LLC739,369$1.85M0.14%00.0%Unchanged
Foresite Capital Management II, LLC690,002$1.73M0.66%−142,334−17.1%Reduced
Charles Schwab Investment Management Inc637,481$1.59M0.00%+8,403+1.3%Added
Jacobs Levy Equity Management, Inc587,164$1.47M0.01%+587,164New
Assenagon Asset Management S.A.576,484$1.44M0.01%+359,464+165.6%Added
HRT Financial LP567,836$1.42M0.01%+458,308+418.4%Added
Renaissance Technologies LLC509,188$1.27M0.00%+509,188New
BNP Paribas Arbitrage, SA482,794$1.21M0.00%+466,413+2,847.3%Added
Redmile Group, LLC454,475$1.14M0.03%−7,004,185−93.9%Reduced
Healthcare of Ontario Pension Plan Trust Fund403,200$1.01M0.00%+403,200New
ExodusPoint Capital Management, LP359,472$899.0K0.01%+359,472New
Hennion & Walsh Asset Management, Inc.346,830$867.0K0.04%−97,168−21.9%Reduced
Bank of New York Mellon Corp320,177$800.0K0.00%+16,414+5.4%Added
Susquehanna International Group, LLP315,462$789.0K0.00%+59,906+23.4%Added
Two Sigma Advisers, LP315,400$789.0K0.00%+315,400New
Nuveen Asset Management, LLC284,858$783.0K0.00%−14,034−4.7%Reduced
Qube Research & Technologies Ltd293,126$733.0K0.01%+293,126New
Rhenman & Partners Asset Management AB265,000$702.0K0.05%00.0%Unchanged
D. E. Shaw & Co., Inc.259,522$649.0K0.00%+259,522New
Toronto Dominion Bank213,121$533.0K0.00%+213,121New
JPMorgan Chase & Co206,768$517.0K0.00%−64,653−23.8%Reduced
Macquarie Group Ltd205,831$515.0K0.00%00.0%Unchanged
Nomura Holdings Inc203,197$509.0K0.00%+203,197New
Jane Street Group, LLC192,280$480.0K0.00%+86,745+82.2%Added
Cubist Systematic Strategies, LLC189,987$475.0K0.00%+170,156+858.0%Added
Barclays PLC165,530$414.0K0.00%+31,809+23.8%Added
Swiss National Bank157,000$393.0K0.00%00.0%Unchanged
Foresite Capital Management I, LLC143,759$359.0K0.32%−150,000−51.1%Reduced
Tudor Investment Corp Et Al142,647$357.0K0.01%+142,647New
Parametric Portfolio Associates LLC134,924$337.0K0.00%+69,471+106.1%Added
Ergoteles LLC129,782$324.0K0.01%+129,782New
Gsa Capital Partners LLP124,500$311.0K0.04%+52,848+73.8%Added
Prudential Financial Inc123,040$308.0K0.00%+85,725+229.7%Added
State of Wisconsin Investment Board120,000$300.0K0.00%00.0%Unchanged
Rhumbline Advisers112,716$282.0K0.00%−1,123−1.0%Reduced
California State Teachers Retirement System108,871$272.0K0.00%+1,906+1.8%Added
UBS Asset Management Americas Inc101,289$253.2K0.00%00.0%Unchanged
Squarepoint Ops LLC100,416$251.0K0.00%+100,416New
Alliancebernstein L.P.96,103$240.0K0.00%−6,400−6.2%Reduced
Credit Suisse AG92,239$230.0K0.00%+4,395+5.0%Added
Russell Investments Group, Ltd.85,939$213.0K0.00%+77,039+865.6%Added
Graham Capital Management, L.P.74,219$185.0K0.01%+74,219New
Invesco Ltd.66,936$167.0K0.00%−5,020−7.0%Reduced
Connor, Clark & Lunn Investment Management Ltd.64,493$161.0K0.00%+64,493New
State Board of Administration of Florida Retirement System63,127$158.0K0.00%+25,876+69.5%Added
Legal & General Group Plc62,767$157.0K0.00%00.0%Unchanged
Price T Rowe Associates Inc57,258$143.0K0.00%−36,900−39.2%Reduced
Deutsche Bank AG56,748$142.0K0.00%−33,746−37.3%Reduced
Engineers Gate Manager LP55,116$138.0K0.01%+55,116New
Algert Global LLC54,360$136.0K0.02%+54,360New
Manufacturers Life Insurance Company, The51,916$130.0K0.00%+1,010+2.0%Added
New York State Common Retirement Fund50,988$127.0K0.00%−123−0.2%Reduced
Alpine Global Management, LLC49,392$123.0K0.02%+49,392New
American International Group, Inc.48,612$122.0K0.00%−530−1.1%Reduced
Virginia Retirement Systems Et Al45,400$114.0K0.00%+33,500+281.5%Added
Quantbot Technologies LP44,877$112.0K0.01%+44,877New
Wedbush Securities Inc43,133$108.0K0.00%00.0%Unchanged
Wells Fargo & Company43,246$108.0K0.00%+43,127+36,241.2%Added
Virtu Financial LLC42,750$107.0K0.01%+42,750New
Voya Investment Management LLC35,402$89.0K0.00%−1,770−4.8%Reduced
Walleye Capital LLC35,478$89.0K0.00%+35,478New
ProShare Advisors LLC34,618$87.0K0.00%+1,270+3.8%Added
PDT Partners, LLC31,115$78.0K0.01%+31,115New
Caxton Associates LP30,300$76.0K0.01%+30,300New
Tower Research Capital LLC (TRC)28,603$72.0K0.00%+11,996+72.2%Added
Citigroup Inc28,258$71.0K0.00%−202,629−87.8%Reduced
Principal Financial Group Inc27,797$70.0K0.00%−11,791−29.8%Reduced
Metropolitan Life Insurance Co26,763$66.9K0.00%+4,410+19.7%Added
Balyasny Asset Management LLC25,990$65.0K0.00%+25,990New
BP PLC24,687$62.0K0.32%00.0%Unchanged
HarbourVest Partners LLC24,686$62.0K0.01%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.23,964$60.0K0.00%+574+2.5%Added
Jasper Ridge Partners, L.P.21,619$54.0K0.00%00.0%Unchanged
Royal Bank of Canada20,806$52.0K0.00%+10,376+99.5%Added
Weiss Multi-Strategy Advisers LLC20,000$50.0K0.00%−4,037−16.8%Reduced
Arizona State Retirement System19,264$48.0K0.00%−180−0.9%Reduced
LPL Financial LLC18,450$46.0K0.00%−15,028−44.9%Reduced
State of Wyoming18,367$46.0K0.02%−437−2.3%Reduced
AQR Capital Management LLC18,243$46.0K0.00%+18,243New
Group One Trading, L.P.17,539$44.0K0.00%+17,539New