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Enanta Pharmaceuticals Inc

ENTA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001177648

No open-market purchases or sales by Enanta Pharmaceuticals Inc insiders were filed in the last 90 days; 122 institutions reported holding it in 13F filings for Q2 2026, worth $397.2M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Enanta Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
132
+12 vs. Q3 2025
Shares held
26.4M
+7.45M (+39.3%) vs. Q3 2025
Total value
$416.1M
+$189.6M (+83.7%) vs. Q3 2025
New holders
36
45 more added
Sold out
24
28 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ENTA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 132 institutions
Q1 2021: 150 institutionsQ2 2021: 152 institutionsQ3 2021: 149 institutionsQ4 2021: 181 institutionsQ1 2022: 170 institutionsQ2 2022: 155 institutionsQ3 2022: 160 institutionsQ4 2022: 147 institutionsQ1 2023: 145 institutionsQ2 2023: 134 institutionsQ3 2023: 132 institutionsQ4 2023: 106 institutionsQ1 2024: 108 institutionsQ2 2024: 101 institutionsQ3 2024: 112 institutionsQ4 2024: 108 institutionsQ1 2025: 110 institutionsQ2 2025: 108 institutionsQ3 2025: 122 institutionsQ4 2025: 132 institutionsQ1 2026: 133 institutionsQ2 2026: 122 institutions
Value heldQ4 2025: $416.1M
Q1 2021: $956.7MQ2 2021: $828.7MQ3 2021: $1.10BQ4 2021: $1.40BQ1 2022: $1.40BQ2 2022: $956.3MQ3 2022: $1.02BQ4 2022: $894.5MQ1 2023: $805.3MQ2 2023: $438.4MQ3 2023: $225.0MQ4 2023: $188.4MQ1 2024: $391.4MQ2 2024: $287.0MQ3 2024: $220.0MQ4 2024: $114.5MQ1 2025: $102.8MQ2 2025: $139.4MQ3 2025: $227.1MQ4 2025: $416.1MQ1 2026: $338.1MQ2 2026: $397.2M
Institutions holding ENTA and their total value by quarter
QuarterHoldersValue
Q2 2026122$397.2M
Q1 2026133$338.1M
Q4 2025132$416.1M
Q3 2025122$227.1M
Q2 2025108$139.4M
Q1 2025110$102.8M
Q4 2024108$114.5M
Q3 2024112$220.0M
Q2 2024101$287.0M
Q1 2024108$391.4M
Q4 2023106$188.4M
Q3 2023132$225.0M
Q2 2023134$438.4M
Q1 2023145$805.3M
Q4 2022147$894.5M
Q3 2022160$1.02B
Q2 2022155$956.3M
Q1 2022170$1.40B
Q4 2021181$1.40B
Q3 2021149$1.10B
Q2 2021152$828.7M
Q1 2021150$956.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Enanta Pharmaceuticals Inc; share changes are against Q3 2025.

Institutions holding ENTA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
GAMMA Investing LLC1,331$21.0K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC1,148$18.1K0.00%00.0%Unchanged
Simplex Trading, LLC922$14.5K0.00%+75+8.9%Added
Amalgamated Bank857$14.0K0.00%+190+28.5%Added
Royal Bank of Canada880$13.0K0.00%−301−25.5%Reduced
The PNC Financial Services Group, Inc.786$12.4K0.00%−12−1.5%Reduced
Tower Research Capital LLC (TRC)721$11.4K0.00%−1,154−61.5%Reduced
True Wealth Design, LLC645$10.2K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.565$8.91K0.00%+117+26.1%Added
Rockefeller Capital Management L.P.514$8.11K0.00%+514New
Smartleaf Asset Management LLC410$6.52K0.00%00.0%Unchanged
IFP Advisors, Inc396$6.25K0.00%00.0%Unchanged
Comerica Bank367$5.79K0.00%00.0%Unchanged
Red Tortoise LLC364$5.74K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC340$5.36K0.00%−510−60.0%Reduced
Optiver Holding B.V.258$4.07K0.00%00.0%Unchanged
Rothschild Investment LLC253$3.99K0.00%−12−4.5%Reduced
Allworth Financial LP228$3.60K0.00%−5−2.1%Reduced
Johnson Financial Group, Inc.188$2.96K0.00%00.0%Unchanged
Farther Finance Advisors, LLC169$2.67K0.00%00.0%Unchanged
Daiwa Securities Group Inc.96$2.00K0.00%+96New
Torren Management, LLC120$1.89K0.00%+120New
Parkside Financial Bank & Trust71$1.12K0.00%00.0%Unchanged
Los Angeles Capital Management LLC103$1.12K0.00%+103New
Sunbelt Securities, Inc.63$9940.00%00.0%Unchanged
Parallel Advisors, LLC51$8040.00%+51New
Advisor Group Holdings, Inc.18$2840.00%−70−79.5%Reduced
Raffa Wealth Management, LLC11$1730.00%00.0%Unchanged
MAI Capital Management7$1110.00%+7New
SRS Capital Advisors, Inc.6$950.00%−7,756−99.9%Reduced
SBI Securities Co., Ltd.1$160.00%00.0%Unchanged
Covestor Ltd15$00.00%−1−6.3%Reduced
Commodore Capital LP0$00.00%−800,000−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−169,048−100.0%Sold out
Trexquant Investment LP0$00.00%−127,363−100.0%Sold out
Tang Capital Management LLC0$00.00%−126,655−100.0%Sold out
StemPoint Capital LP0$00.00%−75,194−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−37,323−100.0%Sold out
PharVision Advisers, LLC0$00.00%−35,846−100.0%Sold out
HRT Financial LP0$00.00%−33,188−100.0%Sold out
Skopos Labs, Inc.0$00.00%−43,153−100.0%Sold out
Jane Street Group, LLC0$00.00%−19,165−100.0%Sold out
Ameriprise Financial Inc0$00.00%−18,007−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−17,856−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−15,549−100.0%Sold out
Public Employees Retirement System of Ohio0$00.00%−14,412−100.0%Sold out
Harvest Investment Services, LLC0$00.00%−12,193−100.0%Sold out
Algert Global LLC0$00.00%−11,106−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−10,443−100.0%Sold out
HSBC Holdings PLC0$00.00%−10,415−100.0%Sold out
Quarry LP0$00.00%−6,752−100.0%Sold out
Group One Trading, L.P.0$00.00%−800−100.0%Sold out
Sachetta, LLC0$00.00%−100−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−56−100.0%Sold out
Jones Financial Companies LLLP0$00.00%−60−100.0%Sold out
Advisory Services Network, LLC0$00.00%−4−100.0%Sold out
Cubist Systematic Strategies, LLC––––Not filed
Point72 (DIFC) Ltd––––Not filed