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Enanta Pharmaceuticals Inc

ENTA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001177648

No open-market purchases or sales by Enanta Pharmaceuticals Inc insiders were filed in the last 90 days; 122 institutions reported holding it in 13F filings for Q2 2026, worth $397.2M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Enanta Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
132
+12 vs. Q3 2025
Shares held
26.4M
+7.45M (+39.3%) vs. Q3 2025
Total value
$416.1M
+$189.6M (+83.7%) vs. Q3 2025
New holders
36
45 more added
Sold out
24
28 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ENTA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 132 institutions
Q1 2021: 150 institutionsQ2 2021: 152 institutionsQ3 2021: 149 institutionsQ4 2021: 181 institutionsQ1 2022: 170 institutionsQ2 2022: 155 institutionsQ3 2022: 160 institutionsQ4 2022: 147 institutionsQ1 2023: 145 institutionsQ2 2023: 134 institutionsQ3 2023: 132 institutionsQ4 2023: 106 institutionsQ1 2024: 108 institutionsQ2 2024: 101 institutionsQ3 2024: 112 institutionsQ4 2024: 108 institutionsQ1 2025: 110 institutionsQ2 2025: 108 institutionsQ3 2025: 122 institutionsQ4 2025: 132 institutionsQ1 2026: 133 institutionsQ2 2026: 122 institutions
Value heldQ4 2025: $416.1M
Q1 2021: $956.7MQ2 2021: $828.7MQ3 2021: $1.10BQ4 2021: $1.40BQ1 2022: $1.40BQ2 2022: $956.3MQ3 2022: $1.02BQ4 2022: $894.5MQ1 2023: $805.3MQ2 2023: $438.4MQ3 2023: $225.0MQ4 2023: $188.4MQ1 2024: $391.4MQ2 2024: $287.0MQ3 2024: $220.0MQ4 2024: $114.5MQ1 2025: $102.8MQ2 2025: $139.4MQ3 2025: $227.1MQ4 2025: $416.1MQ1 2026: $338.1MQ2 2026: $397.2M
Institutions holding ENTA and their total value by quarter
QuarterHoldersValue
Q2 2026122$397.2M
Q1 2026133$338.1M
Q4 2025132$416.1M
Q3 2025122$227.1M
Q2 2025108$139.4M
Q1 2025110$102.8M
Q4 2024108$114.5M
Q3 2024112$220.0M
Q2 2024101$287.0M
Q1 2024108$391.4M
Q4 2023106$188.4M
Q3 2023132$225.0M
Q2 2023134$438.4M
Q1 2023145$805.3M
Q4 2022147$894.5M
Q3 2022160$1.02B
Q2 2022155$956.3M
Q1 2022170$1.40B
Q4 2021181$1.40B
Q3 2021149$1.10B
Q2 2021152$828.7M
Q1 2021150$956.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Enanta Pharmaceuticals Inc; share changes are against Q3 2025.

Institutions holding ENTA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Janus Henderson Group PLC3,729,659$58.8M0.03%+1,782,745+91.6%Added
BlackRock, Inc.3,076,282$48.5M0.00%+1,243,302+67.8%Added
Farallon Capital Management, L.L.C.2,772,262$43.7M0.23%+650,000+30.6%Added
Krensavage Asset Management, LLC2,766,390$43.6M15.41%+651,946+30.8%Added
Vanguard Group Inc2,301,794$36.3M0.00%+362,965+18.7%Added
Deep Track Capital, LP1,956,867$30.9M0.70%+1,956,867New
Acadian Asset Management LLC885,126$13.9M0.02%+18,089+2.1%Added
Millennium Management LLC670,428$10.6M0.01%−277,656−29.3%Reduced
Geode Capital Management, LLC645,791$10.2M0.00%+152,597+30.9%Added
Renaissance Technologies LLC642,200$10.1M0.02%+162,600+33.9%Added
State Street Corp523,715$8.26M0.00%+51,723+11.0%Added
Point72 Asset Management, L.P.438,939$6.92M0.01%+138,939+46.3%Added
Hillsdale Investment Management Inc.422,300$6.66M0.18%+422,300New
Spruce Street Capital LP389,687$6.15M2.03%+389,687New
Marshall Wace, LLP385,276$6.08M0.01%+109,887+39.9%Added
Morgan Stanley339,918$5.36M0.00%+57,287+20.3%Added
Two Sigma Investments, LP285,448$4.50M0.01%+224,726+370.1%Added
Invesco Ltd.253,811$4.00M0.00%+194,113+325.2%Added
AQR Capital Management LLC234,835$3.70M0.00%+7,990+3.5%Added
Northern Trust Corp229,889$3.63M0.00%+33,993+17.4%Added
Goldman Sachs Group Inc218,816$3.45M0.00%+52,383+31.5%Added
Charles Schwab Investment Management Inc218,636$3.45M0.00%+52,089+31.3%Added
Dimensional Fund Advisors LP211,614$3.34M0.00%−58,454−21.6%Reduced
D. E. Shaw & Co., Inc.167,714$2.64M0.00%−58,030−25.7%Reduced
Two Sigma Advisers, LP143,300$2.26M0.00%+18,200+14.5%Added
JPMorgan Chase & Co112,964$1.78M0.00%−10,853−8.8%Reduced
Connor, Clark & Lunn Investment Management Ltd.103,903$1.64M0.00%+26,397+34.1%Added
Stonepine Capital Management, LLC100,000$1.58M1.25%−205,000−67.2%Reduced
BNP Paribas Arbitrage, SA99,884$1.58M0.00%+80,064+404.0%Added
SEI Investments Co98,782$1.56M0.00%+24,929+33.8%Added
Citadel Advisors LLC93,158$1.47M0.00%+93,158New
Nuveen, LLC86,056$1.36M0.00%−78,704−47.8%Reduced
Opaleye Management Inc.75,000$1.18M0.16%+75,000New
Bank of New York Mellon Corp72,588$1.14M0.00%+12,095+20.0%Added
PDT Partners, LLC69,197$1.09M0.07%−16,825−19.6%Reduced
Panagora Asset Management Inc66,990$1.06M0.00%+66,990New
Bank of America Corp65,978$1.04M0.00%+36,026+120.3%Added
Squarepoint Ops LLC65,966$1.04M0.00%+65,966New
Diadema Partners LP65,138$1.03M0.61%+65,138New
Wellington Management Group LLP63,219$997.0K0.00%+63,219New
Barclays PLC54,989$867.2K0.00%+13,368+32.1%Added
Campbell & CO Investment Adviser LLC54,149$853.9K0.04%+35,294+187.2%Added
Arrowstreet Capital, Limited Partnership52,728$831.5K0.00%+52,728New
Susquehanna Fundamental Investments, LLC50,434$795.3K0.03%00.0%Unchanged
Assenagon Asset Management S.A.45,877$723.5K0.00%−8,380−15.4%Reduced
Man Group plc43,847$691.5K0.00%+3,691+9.2%Added
ADAR1 Capital Management, LLC41,357$652.2K0.05%+41,357New
EAM Investors, LLC40,952$645.8K0.07%+40,952New
Prudential Financial Inc40,015$631.0K0.00%+40,015New
Sio Capital Management, LLC40,000$630.8K0.10%+40,000New
Bank of Montreal37,484$591.1K0.00%+3,616+10.7%Added
Ieq Capital, LLC36,385$573.8K0.00%−1,301−3.5%Reduced
American Century Companies Inc33,764$532.5K0.00%−14,807−30.5%Reduced
Alliancebernstein L.P.33,740$532.1K0.00%00.0%Unchanged
Quantinno Capital Management LP33,495$528.2K0.00%−3,631−9.8%Reduced
State of Wyoming32,887$518.6K0.06%+32,887New
Franklin Resources Inc32,720$516.0K0.00%+32,720New
Qube Research & Technologies Ltd32,389$510.8K0.00%+20,469+171.7%Added
Wells Fargo & Company30,716$484.4K0.00%+15,117+96.9%Added
Hudson Bay Capital Management LP30,000$473.1K0.00%+30,000New
Bridgeway Capital Management, LLC29,700$468.4K0.01%00.0%Unchanged
Rhumbline Advisers28,849$454.9K0.00%−2,060−6.7%Reduced
Thrivent Financial for Lutherans28,376$448.0K0.00%−5,665−16.6%Reduced
Portland Global Advisors LLC24,275$382.8K0.04%00.0%Unchanged
Deutsche Bank AG24,107$380.2K0.00%+1,055+4.6%Added
Headlands Technologies LLC22,596$356.3K0.03%+22,596New
CWM, LLC20,666$326.0K0.00%+19+0.1%Added
State of Wisconsin Investment Board18,608$293.4K0.00%+18,608New
Persistent Asset Partners Ltd17,466$275.4K0.13%+17,466New
Price T Rowe Associates Inc14,410$228.0K0.00%+4,264+42.0%Added
MetLife Investment Management14,408$227.2K0.00%+7,849+119.7%Added
Quest Partners LLC14,178$223.6K0.01%+3,980+39.0%Added
Virtu Financial LLC13,967$220.0K0.01%+13,967New
Jump Financial, LLC13,900$219.2K0.00%+13,900New
Mirae Asset Global ETFs Holdings Ltd.12,668$199.8K0.00%+2,962+30.5%Added
Jain Global LLC12,543$197.8K0.00%+12,543New
Russell Investments Group, Ltd.11,483$182.4K0.00%−4,960−30.2%Reduced
Kingsview Wealth Management, LLC10,653$168.0K0.00%+10,653New
Susquehanna International Group, LLP10,467$165.1K0.00%−106,837−91.1%Reduced
Fox Run Management, L.L.C.10,182$160.6K0.02%+10,182New
Wealth Enhancement Advisory Services, LLC10,721$145.6K0.00%+74+0.7%Added
Canada Pension Plan Investment Board8,900$140.4K0.00%+8,900New
Police & Firemen's Retirement System of New Jersey6,676$105.3K0.00%00.0%Unchanged
New York State Common Retirement Fund6,071$95.7K0.00%−1,700−21.9%Reduced
UBS Group AG5,092$80.3K0.00%−10,215−66.7%Reduced
Atlantic Trust, LLC5,064$79.9K0.01%00.0%Unchanged
China Universal Asset Management Co., Ltd.4,703$74.2K0.01%−4,044−46.2%Reduced
FMR LLC4,312$68.0K0.00%+2,527+141.6%Added
Mirae Asset Global Investments Co., Ltd.3,584$56.5K0.00%+2,758+333.9%Added
STRS Ohio3,200$50.5K0.00%+3,200New
Pinnacle Wealth Planning Services, Inc.2,529$39.9K0.00%+2,529New
Legal & General Group Plc2,438$38.4K0.00%+734+43.1%Added
Seven Fleet Capital Management LP2,270$35.8K0.02%+2,270New
Meeder Asset Management Inc2,025$31.9K0.00%+2,025New
Ameritas Investment Partners, Inc.1,973$31.1K0.00%00.0%Unchanged
California State Teachers Retirement System1,679$26.5K0.00%+423+33.7%Added
Sterling Capital Management LLC1,572$24.8K0.00%+181+13.0%Added
Essential Partners LLC1,516$23.9K0.01%00.0%Unchanged
Versant Capital Management, Inc1,424$22.5K0.00%00.0%Unchanged
Citigroup Inc1,422$22.4K0.00%−680−32.4%Reduced