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Enliven Therapeutics, Inc.

ELVN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001672619

In the last 90 days, Enliven Therapeutics, Inc. insiders filed 0 open-market purchases and 8 sales; 214 institutions reported holding it in 13F filings for Q2 2026, worth $4.06B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Enliven Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
126
−6 vs. Q3 2025
Shares held
62.4M
+3.00M (+5.0%) vs. Q3 2025
Total value
$960.9M
−$254.7M (−21.0%) vs. Q3 2025
New holders
20
46 more added
Sold out
26
45 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ELVN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 126 institutions
Q1 2021: 40 institutionsQ2 2021: 31 institutionsQ3 2021: 38 institutionsQ4 2021: 35 institutionsQ1 2022: 31 institutionsQ2 2022: 26 institutionsQ3 2022: 31 institutionsQ4 2022: 36 institutionsQ1 2023: 45 institutionsQ2 2023: 63 institutionsQ3 2023: 61 institutionsQ4 2023: 62 institutionsQ1 2024: 74 institutionsQ2 2024: 93 institutionsQ3 2024: 102 institutionsQ4 2024: 114 institutionsQ1 2025: 122 institutionsQ2 2025: 125 institutionsQ3 2025: 134 institutionsQ4 2025: 126 institutionsQ1 2026: 171 institutionsQ2 2026: 214 institutions
Value heldQ4 2025: $960.9M
Q1 2021: $92.9MQ2 2021: $86.3MQ3 2021: $62.5MQ4 2021: $33.6MQ1 2022: $26.2MQ2 2022: $13.1MQ3 2022: $18.8MQ4 2022: $74.7MQ1 2023: $735.0MQ2 2023: $797.9MQ3 2023: $533.8MQ4 2023: $539.8MQ1 2024: $780.8MQ2 2024: $1.13BQ3 2024: $1.22BQ4 2024: $1.12BQ1 2025: $983.9MQ2 2025: $1.19BQ3 2025: $1.22BQ4 2025: $960.9MQ1 2026: $2.43BQ2 2026: $4.06B
Institutions holding ELVN and their total value by quarter
QuarterHoldersValue
Q2 2026214$4.06B
Q1 2026171$2.43B
Q4 2025126$960.9M
Q3 2025134$1.22B
Q2 2025125$1.19B
Q1 2025122$983.9M
Q4 2024114$1.12B
Q3 2024102$1.22B
Q2 202493$1.13B
Q1 202474$780.8M
Q4 202362$539.8M
Q3 202361$533.8M
Q2 202363$797.9M
Q1 202345$735.0M
Q4 202236$74.7M
Q3 202231$18.8M
Q2 202226$13.1M
Q1 202231$26.2M
Q4 202135$33.6M
Q3 202138$62.5M
Q2 202131$86.3M
Q1 202140$92.9M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Enliven Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding ELVN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Marshall Wace, LLP371,906$5.73M0.01%+31,424+9.2%Added
Dimensional Fund Advisors LP398,893$6.14M0.00%+238,434+148.6%Added
Morgan Stanley411,823$6.34M0.00%+153,439+59.4%Added
Spruce Street Capital LP446,084$6.87M2.27%+446,084New
Candriam Luxembourg S.C.A.453,019$6.98M0.03%−156,333−25.7%Reduced
5AM Venture Management, LLC772,477$11.9M3.74%00.0%Unchanged
Rock Springs Capital Management LP798,405$12.3M0.63%+112,298+16.4%Added
Blackstone Group Inc.954,946$14.7M0.06%−365,646−27.7%Reduced
Soleus Capital Management, L.P.1,025,000$15.8M0.67%+1,025,000New
Geode Capital Management, LLC1,048,722$16.2M0.00%−36,291−3.3%Reduced
State Street Corp1,052,862$16.2M0.00%+87,725+9.1%Added
Pictet Asset Management Holding SA1,303,235$20.1M0.02%−94,852−6.8%Reduced
Capital Research Global Investors1,304,346$20.1M0.00%−11,119−0.8%Reduced
Citadel Advisors LLC1,424,344$21.9M0.01%+263,841+22.7%Added
Novo Holdings A/S1,480,000$22.8M1.77%+53,740+3.8%Added
Point72 Asset Management, L.P.1,504,601$23.2M0.04%+464,191+44.6%Added
Janus Henderson Group PLC1,671,724$25.7M0.01%−121,859−6.8%Reduced
Vanguard Group Inc2,801,665$43.1M0.00%+248,651+9.7%Added
VR Adviser, LLC3,226,331$49.7M2.45%00.0%Unchanged
Polar Capital Holdings Plc3,513,680$54.1M0.25%+418,673+13.5%Added
BlackRock, Inc.3,613,326$55.6M0.00%+94,802+2.7%Added
Fairmount Funds Management LLC3,711,444$57.2M4.35%00.0%Unchanged
Vestal Point Capital, LP3,830,000$59.0M2.16%+2,670,000+230.2%Added
Commodore Capital LP4,692,809$72.3M4.81%00.0%Unchanged
FMR LLC7,107,635$109.5M0.01%−21,561−0.3%Reduced
OrbiMed Advisors LLC7,959,538$122.6M2.51%00.0%Unchanged
Duquesne Family Office LLCSuperinvestorDuquesne Family Office0$00.00%−947,405−100.0%Sold out
First Turn Management, LLC0$00.00%−783,411−100.0%Sold out
Affinity Asset Advisors, LLC0$00.00%−400,000−100.0%Sold out
Cormorant Asset Management, LP0$00.00%−200,000−100.0%Sold out
PFM Health Sciences, LP0$00.00%−156,463−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−73,000−100.0%Sold out
Renaissance Technologies LLC0$00.00%−59,000−100.0%Sold out
Trexquant Investment LP0$00.00%−50,492−100.0%Sold out
NEOS Investment Management LLC0$00.00%−40,314−100.0%Sold out
Tema ETFs LLC0$00.00%−40,314−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−31,438−100.0%Sold out
TD Asset Management Inc0$00.00%−27,518−100.0%Sold out
Winton Group Ltd0$00.00%−16,458−100.0%Sold out
Man Group plc0$00.00%−13,371−100.0%Sold out
Caxton Corp0$00.00%−13,097−100.0%Sold out
Federated Hermes, Inc.0$00.00%−10,811−100.0%Sold out
Silverarc Capital Management, LLC0$00.00%−10,675−100.0%Sold out
BIT Capital GmbH0$00.00%−3,181−100.0%Sold out
Parallel Advisors, LLC0$00.00%−491−100.0%Sold out
ORG Partners LLC0$00.00%−225−100.0%Sold out
US Bancorp0$00.00%−111−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−84−100.0%Sold out
Group One Trading, L.P.0$00.00%−34−100.0%Sold out
Parkside Financial Bank & Trust0$00.00%−25−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−5−100.0%Sold out
Advisory Services Network, LLC0$00.00%−2−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Point72 Europe (London) LLP––––Not filed