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Dyne Therapeutics, Inc.

DYN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001818794

In the last 90 days, Dyne Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 245 institutions reported holding it in 13F filings for Q2 2026, worth $4.23B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Dyne Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
233
+31 vs. Q3 2025
Shares held
177.9M
+23.0M (+14.8%) vs. Q3 2025
Total value
$3.48B
+$1.52B (+77.5%) vs. Q3 2025
New holders
59
96 more added
Sold out
28
58 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DYN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 233 institutions
Q1 2021: 75 institutionsQ2 2021: 76 institutionsQ3 2021: 83 institutionsQ4 2021: 93 institutionsQ1 2022: 94 institutionsQ2 2022: 90 institutionsQ3 2022: 102 institutionsQ4 2022: 113 institutionsQ1 2023: 127 institutionsQ2 2023: 118 institutionsQ3 2023: 114 institutionsQ4 2023: 124 institutionsQ1 2024: 169 institutionsQ2 2024: 193 institutionsQ3 2024: 200 institutionsQ4 2024: 200 institutionsQ1 2025: 205 institutionsQ2 2025: 198 institutionsQ3 2025: 207 institutionsQ4 2025: 233 institutionsQ1 2026: 228 institutionsQ2 2026: 245 institutions
Value heldQ4 2025: $3.48B
Q1 2021: $533.3MQ2 2021: $753.4MQ3 2021: $572.8MQ4 2021: $568.3MQ1 2022: $456.6MQ2 2022: $320.7MQ3 2022: $565.8MQ4 2022: $576.2MQ1 2023: $628.7MQ2 2023: $665.9MQ3 2023: $536.6MQ4 2023: $930.0MQ1 2024: $2.71BQ2 2024: $3.92BQ3 2024: $4.03BQ4 2024: $2.63BQ1 2025: $1.29BQ2 2025: $1.22BQ3 2025: $1.97BQ4 2025: $3.48BQ1 2026: $3.40BQ2 2026: $4.23B
Institutions holding DYN and their total value by quarter
QuarterHoldersValue
Q2 2026245$4.23B
Q1 2026228$3.40B
Q4 2025233$3.48B
Q3 2025207$1.97B
Q2 2025198$1.22B
Q1 2025205$1.29B
Q4 2024200$2.63B
Q3 2024200$4.03B
Q2 2024193$3.92B
Q1 2024169$2.71B
Q4 2023124$930.0M
Q3 2023114$536.6M
Q2 2023118$665.9M
Q1 2023127$628.7M
Q4 2022113$576.2M
Q3 2022102$565.8M
Q2 202290$320.7M
Q1 202294$456.6M
Q4 202193$568.3M
Q3 202183$572.8M
Q2 202176$753.4M
Q1 202175$533.3M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Dyne Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding DYN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Advisor Group Holdings, Inc.635$12.4K0.00%−6−0.9%Reduced
Allworth Financial LP559$10.9K0.00%+64+12.9%Added
Smartleaf Asset Management LLC555$10.7K0.00%+472+568.7%Added
Essential Partners LLC445$8.70K0.00%+6+1.4%Added
The PNC Financial Services Group, Inc.418$8.18K0.00%−42−9.1%Reduced
Daiwa Securities Group Inc.424$8.00K0.00%+53+14.3%Added
US Bancorp400$7.82K0.00%+39+10.8%Added
Optiver Holding B.V.395$7.73K0.00%−508−56.3%Reduced
First Horizon Corp382$7.47K0.00%−8−2.1%Reduced
Signaturefd, LLC320$6.26K0.00%+42+15.1%Added
Truvestments Capital LLC295$5.77K0.00%00.0%Unchanged
Massmutual Trust Co FSB243$4.75K0.00%00.0%Unchanged
Aspect Partners, LLC225$4.40K0.00%−380−62.8%Reduced
Fideuram - Intesa Sanpaolo Private Banking S.P.A.200$3.91K0.00%+200New
Flagship Harbor Advisors, LLC200$3.91K0.00%+200New
National Bank of Canada200$3.91K0.00%+50+33.3%Added
Rothschild Investment LLC170$3.33K0.00%+5+3.0%Added
SBI Securities Co., Ltd.150$2.93K0.00%−10−6.3%Reduced
Geneos Wealth Management Inc.138$2.70K0.00%+138New
EverSource Wealth Advisors, LLC97$1.90K0.00%00.0%Unchanged
IFP Advisors, Inc95$1.86K0.00%−1−1.0%Reduced
MRP Capital Investments, LLC75$1.47K0.00%+75New
Parkside Financial Bank & Trust70$1.37K0.00%+30+75.0%Added
Quadrant Capital Group LLC67$1.31K0.00%00.0%Unchanged
Basecamp Wealth Advisors LLC42$8220.00%+42New
Cornerstone Financial Management LLC40$7820.00%+40New
Parallel Advisors, LLC27$5280.00%00.0%Unchanged
Bell Investment Advisors, Inc26$5090.00%+26New
Larson Financial Group LLC22$4300.00%+3+15.8%Added
SRS Capital Advisors, Inc.18$3520.00%−465−96.3%Reduced
Farther Finance Advisors, LLC17$3330.00%+2+13.3%Added
True Wealth Design, LLC13$2550.00%00.0%Unchanged
Dunhill Financial, LLC1$170.00%+1New
RTW Investments, LP0$00.00%−2,890,567−100.0%Sold out
Paradigm Biocapital Advisors LP0$00.00%−1,898,950−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−800,000−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−729,606−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−710,044−100.0%Sold out
Nantahala Capital Management, LLC0$00.00%−702,884−100.0%Sold out
Schonfeld Strategic Advisors LLC0$00.00%−415,927−100.0%Sold out
Twinbeech Capital LP0$00.00%−115,341−100.0%Sold out
Ikarian Capital, LLC0$00.00%−113,837−100.0%Sold out
Voleon Capital Management LP0$00.00%−111,838−100.0%Sold out
Silverarc Capital Management, LLC0$00.00%−100,000−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−68,888−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−64,517−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−41,587−100.0%Sold out
Public Employees Retirement System of Ohio0$00.00%−33,100−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−29,084−100.0%Sold out
Mariner, LLC0$00.00%−19,541−100.0%Sold out
Compagnie Lombard Odier SCmA0$00.00%−18,000−100.0%Sold out
Quantbot Technologies LP0$00.00%−17,513−100.0%Sold out
Prudential Financial Inc0$00.00%−13,210−100.0%Sold out
Oppenheimer & Co Inc0$00.00%−11,364−100.0%Sold out
Arkadios Wealth Advisors0$00.00%−10,104−100.0%Sold out
Eversept Partners, LP0$00.00%−10,000−100.0%Sold out
Quarry LP0$00.00%−7,250−100.0%Sold out
GPS Wealth Strategies Group, LLC0$00.00%−400−100.0%Sold out
Washington Trust Advisors, Inc.0$00.00%−125−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−37−100.0%Sold out
Advisory Services Network, LLC0$00.00%−14−100.0%Sold out
MPM Asset Management LLC––––Not filed
AXA Investment Managers S.A.––––Not filed
Point72 Hong Kong Ltd––––Not filed
CIBC Bancorp USA Inc.––––Not filed
Point72 Europe (London) LLP––––Not filed