Dyne Therapeutics, Inc.
DYN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001818794
In the last 90 days, Dyne Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 245 institutions reported holding it in 13F filings for Q2 2026, worth $4.23B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Dyne Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 233
- +31 vs. Q3 2025
- Shares held
- 177.9M
- +23.0M (+14.8%) vs. Q3 2025
- Total value
- $3.48B
- +$1.52B (+77.5%) vs. Q3 2025
- New holders
- 59
- 96 more added
- Sold out
- 28
- 58 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting DYN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 245 | $4.23B |
| Q1 2026 | 228 | $3.40B |
| Q4 2025 | 233 | $3.48B |
| Q3 2025 | 207 | $1.97B |
| Q2 2025 | 198 | $1.22B |
| Q1 2025 | 205 | $1.29B |
| Q4 2024 | 200 | $2.63B |
| Q3 2024 | 200 | $4.03B |
| Q2 2024 | 193 | $3.92B |
| Q1 2024 | 169 | $2.71B |
| Q4 2023 | 124 | $930.0M |
| Q3 2023 | 114 | $536.6M |
| Q2 2023 | 118 | $665.9M |
| Q1 2023 | 127 | $628.7M |
| Q4 2022 | 113 | $576.2M |
| Q3 2022 | 102 | $565.8M |
| Q2 2022 | 90 | $320.7M |
| Q1 2022 | 94 | $456.6M |
| Q4 2021 | 93 | $568.3M |
| Q3 2021 | 83 | $572.8M |
| Q2 2021 | 76 | $753.4M |
| Q1 2021 | 75 | $533.3M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Dyne Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Morgan Stanley | 1,213,559 | $23.7M | 0.00% | −205,448−14.5% | Reduced |
| Logos Global Management LP | 1,250,000 | $24.4M | 1.63% | −1,150,000−47.9% | Reduced |
| Polar Capital Holdings Plc | 1,269,131 | $24.8M | 0.11% | +739,743+139.7% | Added |
| MPM Oncology Impact Management LP | 1,405,388 | $27.5M | 3.15% | −40,973−2.8% | Reduced |
| Palo Alto Investors LP | 1,472,197 | $28.8M | 4.01% | +209,523+16.6% | Added |
| Braidwell LP | 1,478,329 | $28.9M | 0.92% | −1,252,152−45.9% | Reduced |
| Samlyn Capital, LLC | 1,493,075 | $29.2M | 0.47% | +1,493,075 | New |
| Saturn V Capital Management LLC | 1,788,616 | $35.0M | 6.42% | −885,853−33.1% | Reduced |
| Franklin Resources Inc | 2,006,638 | $39.2M | 0.01% | +608,108+43.5% | Added |
| VR Adviser, LLC | 2,173,913 | $42.5M | 2.10% | 00.0% | Unchanged |
| OrbiMed Advisors LLC | 2,202,184 | $43.1M | 0.88% | −112,000−4.8% | Reduced |
| Sofinnova Investments, Inc. | 2,254,161 | $44.1M | 1.90% | +1,268,333+128.7% | Added |
| Goldman Sachs Group Inc | 2,283,191 | $44.7M | 0.01% | +382,976+20.2% | Added |
| Price T Rowe Associates Inc | 2,323,789 | $45.5M | 0.00% | +925,702+66.2% | Added |
| Vivo Capital, LLC | 2,614,960 | $51.1M | 3.31% | 00.0% | Unchanged |
| Deep Track Capital, LP | 2,650,000 | $51.8M | 1.18% | +650,000+32.5% | Added |
| Frazier Life Sciences Management, L.P. | 3,153,082 | $61.7M | 1.66% | +434,977+16.0% | Added |
| Armistice Capital, LLC | 3,249,708 | $63.6M | 1.56% | +185,708+6.1% | Added |
| Geode Capital Management, LLC | 3,263,429 | $63.8M | 0.00% | +395,824+13.8% | Added |
| Perceptive Advisors LLC | 3,478,944 | $68.0M | 1.25% | +2,938,500+543.7% | Added |
| Siren, L.L.C. | 3,502,941 | $68.5M | 2.04% | −1,226,233−25.9% | Reduced |
| JPMorgan Chase & Co | 3,549,909 | $69.4M | 0.00% | +184,664+5.5% | Added |
| TCG Crossover Management, LLC | 4,615,144 | $90.3M | 2.99% | 00.0% | Unchanged |
| Orbis Allan Gray Ltd | 4,801,928 | $93.9M | 0.39% | +4,801,928 | New |
| Adage Capital Partners GP, L.L.C. | 5,172,000 | $101.2M | 0.15% | +1,618,000+45.5% | Added |
| FCPM III Services B.V. | 5,462,846 | $106.9M | 14.01% | 00.0% | Unchanged |
| FMR LLC | 6,569,921 | $128.5M | 0.01% | +1,168,005+21.6% | Added |
| State Street Corp | 6,692,745 | $130.9M | 0.00% | +1,423,828+27.0% | Added |
| Atlas Venture Life Science Advisors, LLC | 9,130,465 | $178.6M | 20.64% | 00.0% | Unchanged |
| BlackRock, Inc. | 11,190,838 | $218.9M | 0.00% | +1,555,929+16.1% | Added |
| Vanguard Group Inc | 11,215,565 | $219.4M | 0.00% | +1,455,151+14.9% | Added |
| Janus Henderson Group PLC | 13,887,722 | $271.6M | 0.12% | −857,783−5.8% | Reduced |
| T. Rowe Price Investment Management, Inc. | 17,540,089 | $343.1M | 0.22% | +14,727,667+523.7% | Added |
| RTW Investments, LP | 0 | $0 | 0.00% | −2,890,567−100.0% | Sold out |
| Paradigm Biocapital Advisors LP | 0 | $0 | 0.00% | −1,898,950−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −800,000−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −729,606−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −710,044−100.0% | Sold out |
| Nantahala Capital Management, LLC | 0 | $0 | 0.00% | −702,884−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −415,927−100.0% | Sold out |
| Twinbeech Capital LP | 0 | $0 | 0.00% | −115,341−100.0% | Sold out |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −113,837−100.0% | Sold out |
| Voleon Capital Management LP | 0 | $0 | 0.00% | −111,838−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −100,000−100.0% | Sold out |
| Dark Forest Capital Management LP | 0 | $0 | 0.00% | −68,888−100.0% | Sold out |
| Campbell & CO Investment Adviser LLC | 0 | $0 | 0.00% | −64,517−100.0% | Sold out |
| D. E. Shaw & Co., Inc. | 0 | $0 | 0.00% | −41,587−100.0% | Sold out |
| Public Employees Retirement System of Ohio | 0 | $0 | 0.00% | −33,100−100.0% | Sold out |
| Boothbay Fund Management, LLC | 0 | $0 | 0.00% | −29,084−100.0% | Sold out |
| Mariner, LLC | 0 | $0 | 0.00% | −19,541−100.0% | Sold out |
| Compagnie Lombard Odier SCmA | 0 | $0 | 0.00% | −18,000−100.0% | Sold out |
| Quantbot Technologies LP | 0 | $0 | 0.00% | −17,513−100.0% | Sold out |
| Prudential Financial Inc | 0 | $0 | 0.00% | −13,210−100.0% | Sold out |
| Oppenheimer & Co Inc | 0 | $0 | 0.00% | −11,364−100.0% | Sold out |
| Arkadios Wealth Advisors | 0 | $0 | 0.00% | −10,104−100.0% | Sold out |
| Eversept Partners, LP | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Quarry LP | 0 | $0 | 0.00% | −7,250−100.0% | Sold out |
| GPS Wealth Strategies Group, LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Washington Trust Advisors, Inc. | 0 | $0 | 0.00% | −125−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −37−100.0% | Sold out |
| Advisory Services Network, LLC | 0 | $0 | 0.00% | −14−100.0% | Sold out |
| MPM Asset Management LLC | – | – | – | – | Not filed |
| AXA Investment Managers S.A. | – | – | – | – | Not filed |
| Point72 Hong Kong Ltd | – | – | – | – | Not filed |
| CIBC Bancorp USA Inc. | – | – | – | – | Not filed |
| Point72 Europe (London) LLP | – | – | – | – | Not filed |