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Durect Corp

DRRXDelisted Sep 11, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001082038

Durect Corp was delisted on Sep 11, 2025; its insiders filed their last Form 4 on Sep 16, 2025; 40 institutions reported holding it in 13F filings for Q2 2025, worth $4.44M in total; no superinvestor held it.

13F holders, Q4 2021

Institutional positions in Durect Corp as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
101
−8 vs. Q3 2021
Shares held
115.2M
−266.3K (−0.2%) vs. Q3 2021
Total value
$113.5M
−$34.3M (−23.2%) vs. Q3 2021
New holders
13
30 more added
Sold out
21
35 more reduced

1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DRRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 101 institutions
Q1 2021: 113 institutionsQ2 2021: 112 institutionsQ3 2021: 110 institutionsQ4 2021: 101 institutionsQ1 2022: 97 institutionsQ2 2022: 89 institutionsQ3 2022: 73 institutionsQ4 2022: 56 institutionsQ1 2023: 55 institutionsQ2 2023: 57 institutionsQ3 2023: 51 institutionsQ4 2023: 49 institutionsQ1 2024: 41 institutionsQ2 2024: 45 institutionsQ3 2024: 44 institutionsQ4 2024: 43 institutionsQ1 2025: 38 institutionsQ2 2025: 40 institutionsQ3 2025: 2 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2021: $113.5M
Q1 2021: $235.1MQ2 2021: $190.8MQ3 2021: $148.1MQ4 2021: $113.5MQ1 2022: $77.2MQ2 2022: $47.6MQ3 2022: $54.5MQ4 2022: $35.1MQ1 2023: $45.1MQ2 2023: $44.9MQ3 2023: $24.7MQ4 2023: $4.02MQ1 2024: $8.40MQ2 2024: $9.70MQ3 2024: $9.50MQ4 2024: $5.12MQ1 2025: $5.27MQ2 2025: $4.44MQ3 2025: $2.93KQ4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding DRRX and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20252$2.93K
Q2 202540$4.44M
Q1 202538$5.27M
Q4 202443$5.12M
Q3 202444$9.50M
Q2 202445$9.70M
Q1 202441$8.40M
Q4 202349$4.02M
Q3 202351$24.7M
Q2 202357$44.9M
Q1 202355$45.1M
Q4 202256$35.1M
Q3 202273$54.5M
Q2 202289$47.6M
Q1 202297$77.2M
Q4 2021101$113.5M
Q3 2021110$148.1M
Q2 2021112$190.8M
Q1 2021113$235.1M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Durect Corp; share changes are against Q3 2021.

Institutions holding DRRX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Bleichroeder LP26,414,656$26.0M4.06%00.0%Unchanged
Lion Point Capital, LP15,486,004$15.3M5.04%00.0%Unchanged
BlackRock Inc.13,937,117$13.7M0.00%−404,327−2.8%Reduced
Vanguard Group Inc11,295,979$11.1M0.00%−128,179−1.1%Reduced
Ingalls & Snyder LLC7,301,855$7.20M0.33%+2,9000.0%Added
Antara Capital LP4,379,837$4.32M0.42%+1,117,151+34.2%Added
State Street Corp3,925,326$3.87M0.00%−428,311−9.8%Reduced
Geode Capital Management, LLC3,850,263$3.79M0.00%−23,185−0.6%Reduced
CM Management, LLC2,925,195$2.88M2.18%+275,195+10.4%Added
Renaissance Technologies LLC2,911,430$2.87M0.00%−74,500−2.5%Reduced
JPMorgan Chase & Co2,833,465$2.79M0.00%−94,657−3.2%Reduced
Beirne Wealth Consulting Services, LLC2,509,671$2.47M1.35%+143,864+6.1%Added
Northern Trust Corp2,081,302$2.05M0.00%−358,191−14.7%Reduced
Gagnon Securities LLC1,401,051$1.38M0.21%+73,647+5.5%Added
Harbert Fund Advisors, Inc.1,271,402$1.25M0.58%00.0%Unchanged
Tocqueville Asset Management L.P.901,700$889.0K0.01%+29,900+3.4%Added
Jefferies Group LLC850,653$838.7K0.02%00.0%Unchanged
Ironwood Investment Management LLC833,194$821.0K0.41%−7,487−0.9%Reduced
Millennium Management LLC823,734$812.0K0.00%+691,102+521.1%Added
Kings Point Capital Management820,330$809.0K0.07%00.0%Unchanged
Nuveen Asset Management, LLC836,584$757.0K0.00%−75,614−8.3%Reduced
Bank of New York Mellon Corp681,986$672.0K0.00%+12,202+1.8%Added
Charles Schwab Investment Management Inc594,175$586.0K0.00%00.0%Unchanged
Two Sigma Advisers, LP492,100$485.0K0.00%+54,900+12.6%Added
Dimensional Fund Advisors LP276,992$273.0K0.00%−49,024−15.0%Reduced
Barclays PLC274,589$270.0K0.00%+160,615+140.9%Added
Raymond James & Associates263,500$260.0K0.00%−7,000−2.6%Reduced
Anson Funds Management LP255,105$252.0K0.03%+255,105New
Two Sigma Investments, LP247,855$244.0K0.00%+247,855New
Goldman Sachs Group Inc224,588$221.0K0.00%+33,252+17.4%Added
Morgan Stanley216,069$213.0K0.00%+74,890+53.0%Added
Jane Street Group, LLC207,990$205.0K0.00%+207,990New
Rhumbline Advisers206,360$203.0K0.00%−4,957−2.3%Reduced
SG Americas Securities, LLC202,647$200.0K0.00%−55,722−21.6%Reduced
Davenport & Co LLC166,750$164.0K0.00%−206,400−55.3%Reduced
Price T Rowe Associates Inc151,918$150.0K0.00%−39,764−20.7%Reduced
Deutsche Bank AG146,706$144.0K0.00%+7,263+5.2%Added
Wells Fargo & Company143,571$141.0K0.00%+50,122+53.6%Added
Cambridge Investment Research Advisors, Inc.142,300$140.0K0.00%−4,000−2.7%Reduced
Kestra Advisory Services, LLC133,910$132.0K0.00%−1,363−1.0%Reduced
Regis Management CO LLC134,250$132.0K0.02%00.0%Unchanged
New York State Common Retirement Fund133,027$131.0K0.00%−279−0.2%Reduced
California State Teachers Retirement System121,546$120.0K0.00%−183,534−60.2%Reduced
American International Group, Inc.120,222$119.0K0.00%−3,597−2.9%Reduced
Citadel Advisors LLC119,144$117.0K0.00%+83,331+232.7%Added
Cowen Prime Advisors LLC113,203$112.0K0.04%+24,525+27.7%Added
Voya Investment Management LLC92,250$91.0K0.00%−325−0.4%Reduced
Invesco Ltd.78,093$77.0K0.00%−19,793−20.2%Reduced
Russell Investments Group, Ltd.78,200$77.0K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System75,399$74.0K0.00%00.0%Unchanged
Bank of America Corp73,390$73.0K0.00%+47,747+186.2%Added
Accredited Investors Inc.68,000$67.0K0.01%00.0%Unchanged
Brown Advisory Inc60,000$59.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP60,305$59.0K0.00%+18,896+45.6%Added
Citigroup Inc57,660$57.0K0.00%+1,300+2.3%Added
HRT Financial LP56,379$55.0K0.00%+56,379New
Royal Bank of Canada51,793$52.0K0.00%+26,528+105.0%Added
BNP Paribas Arbitrage, SA51,367$50.6K0.00%+8,303+19.3%Added
Financial Consulate, Inc49,400$49.0K0.02%00.0%Unchanged
ProShare Advisors LLC49,421$49.0K0.00%+20,430+70.5%Added
Manufacturers Life Insurance Company, The47,719$47.0K0.00%−22,238−31.8%Reduced
Zebra Capital Management LLC47,646$47.0K0.08%00.0%Unchanged
UBS Group AG40,247$40.0K0.00%+25,855+179.6%Added
Amalgamated Bank39,940$39.0K0.00%−1,400−3.4%Reduced
Goelzer Investment Management, Inc.40,000$39.0K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.38,408$38.0K0.00%−32,259−45.6%Reduced
Principal Financial Group Inc38,584$38.0K0.00%−10,677−21.7%Reduced
Ancora Advisors, LLC39,000$38.0K0.00%00.0%Unchanged
SRS Capital Advisors, Inc.33,295$33.0K0.00%−4,000−10.7%Reduced
Blume Capital Management, Inc.31,000$31.0K0.01%00.0%Unchanged
Two Sigma Securities, LLC30,634$30.0K0.01%+18,523+152.9%Added
Manteio Capital LLC30,273$30.0K0.04%+30,273New
Virtu Financial LLC29,562$29.0K0.00%+1,292+4.6%Added
Victory Capital Management Inc27,469$27.0K0.00%−854−3.0%Reduced
Private Advisor Group, LLC26,608$26.0K0.00%−6,058−18.5%Reduced
Tri Locum Partners LP26,387$26.0K0.01%+26,387New
Kovack Advisors, Inc.25,000$25.0K0.00%+25,000New
Engineers Gate Manager LP24,486$24.0K0.00%+200+0.8%Added
Legal & General Group Plc23,316$23.0K0.00%−52,030−69.1%Reduced
Commonwealth Equity Services, LLC22,955$22.0K0.00%+1,000+4.6%Added
Alliancebernstein L.P.19,100$19.0K0.00%00.0%Unchanged
Parametric Portfolio Associates LLC18,537$18.0K0.00%−129−0.7%Reduced
Envestnet Asset Management Inc18,322$18.0K0.00%+377+2.1%Added
Stoneridge Investment Partners LLC17,719$17.0K0.01%00.0%Unchanged
Ameritas Investment Partners, Inc.17,472$17.0K0.00%00.0%Unchanged
Cetera Advisors LLC15,000$15.0K0.00%00.0%Unchanged
IFP Advisors, Inc15,000$15.0K0.00%00.0%Unchanged
Ground Swell Capital, LLC15,704$15.0K0.09%+15,704New
Ergoteles LLC13,949$14.0K0.00%−24,451−63.7%Reduced
Prudential Financial Inc14,760$14.0K0.00%−20,604−58.3%Reduced
Qube Research & Technologies Ltd12,816$13.0K0.00%+12,816New
Mackenzie Financial Corp12,429$12.0K0.00%−828−6.2%Reduced
Janney Montgomery Scott LLC12,037$12.0K0.00%+12,037New
Tower Research Capital LLC (TRC)10,853$11.0K0.00%−2,975−21.5%Reduced
Xponance, Inc.10,722$11.0K0.00%+126+1.2%Added
Navis Wealth Advisors, LLC10,500$10.0K0.01%00.0%Unchanged
Simplex Trading, LLC9,496$9.00K0.00%+9,496New
EverSource Wealth Advisors, LLC1,000$1.00K0.00%+1,000New
Ellevest, Inc.273$00.00%+84+44.4%Added
Sterling Investment Advisors, Ltd.192$00.00%00.0%Unchanged