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Durect Corp

DRRXDelisted Sep 11, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001082038

Durect Corp was delisted on Sep 11, 2025; its insiders filed their last Form 4 on Sep 16, 2025; 40 institutions reported holding it in 13F filings for Q2 2025, worth $4.44M in total; no superinvestor held it.

13F holders, Q3 2021

Institutional positions in Durect Corp as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
110
+1 vs. Q2 2021
Shares held
115.7M
−1.23M (−1.0%) vs. Q2 2021
Total value
$148.1M
−$42.5M (−22.3%) vs. Q2 2021
New holders
9
38 more added
Sold out
8
32 more reduced

3 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting DRRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 110 institutions
Q1 2021: 113 institutionsQ2 2021: 112 institutionsQ3 2021: 110 institutionsQ4 2021: 101 institutionsQ1 2022: 97 institutionsQ2 2022: 89 institutionsQ3 2022: 73 institutionsQ4 2022: 56 institutionsQ1 2023: 55 institutionsQ2 2023: 57 institutionsQ3 2023: 51 institutionsQ4 2023: 49 institutionsQ1 2024: 41 institutionsQ2 2024: 45 institutionsQ3 2024: 44 institutionsQ4 2024: 43 institutionsQ1 2025: 38 institutionsQ2 2025: 40 institutionsQ3 2025: 2 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ3 2021: $148.1M
Q1 2021: $235.1MQ2 2021: $190.8MQ3 2021: $148.1MQ4 2021: $113.5MQ1 2022: $77.2MQ2 2022: $47.6MQ3 2022: $54.5MQ4 2022: $35.1MQ1 2023: $45.1MQ2 2023: $44.9MQ3 2023: $24.7MQ4 2023: $4.02MQ1 2024: $8.40MQ2 2024: $9.70MQ3 2024: $9.50MQ4 2024: $5.12MQ1 2025: $5.27MQ2 2025: $4.44MQ3 2025: $2.93KQ4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding DRRX and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20252$2.93K
Q2 202540$4.44M
Q1 202538$5.27M
Q4 202443$5.12M
Q3 202444$9.50M
Q2 202445$9.70M
Q1 202441$8.40M
Q4 202349$4.02M
Q3 202351$24.7M
Q2 202357$44.9M
Q1 202355$45.1M
Q4 202256$35.1M
Q3 202273$54.5M
Q2 202289$47.6M
Q1 202297$77.2M
Q4 2021101$113.5M
Q3 2021110$148.1M
Q2 2021112$190.8M
Q1 2021113$235.1M

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Durect Corp; share changes are against Q2 2021.

Institutions holding DRRX in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Ellevest, Inc.189$00.00%+189New
Sterling Investment Advisors, Ltd.192$00.00%+192New
O'Shaughnessy Asset Management, LLC3,506$4.00K0.00%00.0%Unchanged
Macquarie Group Ltd3,782$5.00K0.00%00.0%Unchanged
Geneos Wealth Management Inc.5,000$6.00K0.00%00.0%Unchanged
Navis Wealth Advisors, LLC10,500$13.0K0.01%00.0%Unchanged
HSBC Holdings PLC10,308$14.0K0.00%−2,545−19.8%Reduced
Xponance, Inc.10,596$14.0K0.00%−236−2.2%Reduced
Ameriprise Financial Inc12,200$16.0K0.00%−1,600−11.6%Reduced
Rafferty Asset Management, LLC12,679$16.0K0.00%+1,983+18.5%Added
Two Sigma Securities, LLC12,111$16.0K0.00%+12,111New
BDO Wealth Advisors, LLC12,900$17.0K0.00%00.0%Unchanged
Mackenzie Financial Corp13,257$17.0K0.00%+13,257New
Pictet Asset Management SA13,500$17.0K0.00%+13,500New
Tower Research Capital LLC (TRC)13,828$18.0K0.00%−1,064−7.1%Reduced
Great West Life Assurance Co14,581$19.0K0.00%00.0%Unchanged
Cetera Advisors LLC15,000$19.0K0.00%00.0%Unchanged
IFP Advisors, Inc15,000$19.0K0.00%00.0%Unchanged
UBS Group AG14,392$19.0K0.00%+8,392+139.9%Added
Ameritas Investment Partners, Inc.17,472$22.0K0.00%00.0%Unchanged
Squarepoint Ops LLC16,954$22.0K0.00%+16,954New
Stoneridge Investment Partners LLC17,719$23.0K0.01%00.0%Unchanged
Envestnet Asset Management Inc17,945$23.0K0.00%+1,985+12.4%Added
Parametric Portfolio Associates LLC18,666$24.0K0.00%−62,976−77.1%Reduced
Alliancebernstein L.P.19,100$24.0K0.00%−4,900−20.4%Reduced
Commonwealth Equity Services, LLC21,955$28.0K0.00%00.0%Unchanged
Janus Henderson Group PLC22,305$29.0K0.00%+22,305New
Engineers Gate Manager LP24,286$31.0K0.00%+151+0.6%Added
Royal Bank of Canada25,265$32.0K0.00%+3,552+16.4%Added
Bank of America Corp25,643$33.0K0.00%−2,502−8.9%Reduced
Victory Capital Management Inc28,323$36.0K0.00%−1,061−3.6%Reduced
Virtu Financial LLC28,270$36.0K0.00%−410−1.4%Reduced
ProShare Advisors LLC28,991$37.0K0.00%−29,698−50.6%Reduced
Blume Capital Management, Inc.31,000$40.0K0.01%00.0%Unchanged
Metropolitan Life Insurance Co32,153$41.2K0.00%−47,382−59.6%Reduced
Private Advisor Group, LLC32,666$43.0K0.00%+10,849+49.7%Added
Zurcher Kantonalbank (Zurich Cantonalbank)34,582$44.0K0.00%00.0%Unchanged
Prudential Financial Inc35,364$45.0K0.00%+19,409+121.6%Added
Citadel Advisors LLC35,813$46.0K0.00%−163,635−82.0%Reduced
Teacher Retirement System of Texas35,579$46.0K0.00%+9,344+35.6%Added
SRS Capital Advisors, Inc.37,295$48.0K0.01%00.0%Unchanged
Ergoteles LLC38,400$49.0K0.00%+3,800+11.0%Added
Ancora Advisors, LLC39,000$50.0K0.00%+39,000New
Goelzer Investment Management, Inc.40,000$51.0K0.00%00.0%Unchanged
Susquehanna International Group, LLP41,409$53.0K0.00%−56,665−57.8%Reduced
Amalgamated Bank41,340$53.0K0.00%−1,381−3.2%Reduced
BNP Paribas Arbitrage, SA43,064$55.1K0.00%+33,050+330.0%Added
Zebra Capital Management LLC47,646$61.0K0.07%00.0%Unchanged
Financial Consulate, Inc49,400$63.0K0.02%00.0%Unchanged
Tobias Financial Advisors, Inc.48,981$63.0K0.02%00.0%Unchanged
Principal Financial Group Inc49,261$63.0K0.00%+13,091+36.2%Added
Citigroup Inc56,360$72.0K0.00%+33,886+150.8%Added
Brown Advisory Inc60,000$77.0K0.00%00.0%Unchanged
Arizona State Retirement System61,944$79.0K0.00%+1,901+3.2%Added
Accredited Investors Inc.68,000$87.0K0.01%00.0%Unchanged
Manufacturers Life Insurance Company, The69,957$90.0K0.00%−76,247−52.2%Reduced
Advisor Group Holdings, Inc.70,667$91.0K0.00%00.0%Unchanged
State Board of Administration of Florida Retirement System75,399$97.0K0.00%00.0%Unchanged
Legal & General Group Plc75,346$97.0K0.00%+43,655+137.8%Added
Russell Investments Group, Ltd.78,200$100.0K0.00%00.0%Unchanged
MetLife Investment Management86,177$110.3K0.00%+61,647+251.3%Added
Cowen Prime Advisors LLC88,678$114.0K0.04%+4,000+4.7%Added
Voya Investment Management LLC92,575$118.0K0.00%00.0%Unchanged
Wells Fargo & Company93,449$119.0K0.00%−398,796−81.0%Reduced
Invesco Ltd.97,886$125.0K0.00%+20,009+25.7%Added
Barclays PLC113,974$147.0K0.00%+84,497+286.7%Added
American International Group, Inc.123,819$158.0K0.00%−2,942−2.3%Reduced
Millennium Management LLC132,632$170.0K0.00%−349,993−72.5%Reduced
New York State Common Retirement Fund133,306$171.0K0.00%−49,568−27.1%Reduced
Regis Management CO LLC134,250$172.0K0.03%00.0%Unchanged
Kestra Advisory Services, LLC135,273$173.0K0.00%+998+0.7%Added
Deutsche Bank AG139,443$179.0K0.00%−5,942−4.1%Reduced
Morgan Stanley141,179$182.0K0.00%+35,295+33.3%Added
Cambridge Investment Research Advisors, Inc.146,300$187.0K0.00%+5,000+3.5%Added
Goldman Sachs Group Inc191,336$245.0K0.00%−118,561−38.3%Reduced
Price T Rowe Associates Inc191,682$245.0K0.00%+1,771+0.9%Added
Rhumbline Advisers211,317$270.0K0.00%+2,208+1.1%Added
UBS Asset Management Americas Inc215,714$276.1K0.00%00.0%Unchanged
Credit Suisse AG230,700$296.0K0.00%+9,204+4.2%Added
Healthcare Value Capital, LLC250,000$320.0K0.83%+250,000New
SG Americas Securities, LLC258,369$331.0K0.00%+73,469+39.7%Added
Raymond James & Associates270,500$346.0K0.00%+11,000+4.2%Added
California State Teachers Retirement System305,080$391.0K0.00%−7,402−2.4%Reduced
Dimensional Fund Advisors LP326,016$417.0K0.00%−280,102−46.2%Reduced
Davenport & Co LLC373,150$478.0K0.00%00.0%Unchanged
Two Sigma Advisers, LP437,200$560.0K0.00%−428,000−49.5%Reduced
Gsa Capital Partners LLP447,176$572.0K0.06%+52,436+13.3%Added
Swiss National Bank502,500$643.0K0.00%+15,600+3.2%Added
Charles Schwab Investment Management Inc594,175$761.0K0.00%+20,184+3.5%Added
Bank of New York Mellon Corp669,784$857.0K0.00%+49,976+8.1%Added
Kings Point Capital Management820,330$1.05M0.09%−5,000−0.6%Reduced
Ironwood Investment Management LLC840,681$1.08M0.56%−2,608−0.3%Reduced
Jefferies Group LLC850,653$1.09M0.03%00.0%Unchanged
Tocqueville Asset Management L.P.871,800$1.12M0.02%−47,700−5.2%Reduced
Nuveen Asset Management, LLC912,198$1.20M0.00%−20,312−2.2%Reduced
Harbert Fund Advisors, Inc.1,271,402$1.63M0.84%00.0%Unchanged
Gagnon Securities LLC1,327,404$1.70M0.25%−903−0.1%Reduced
Beirne Wealth Consulting Services, LLC2,365,807$3.03M1.72%+151,933+6.9%Added
Northern Trust Corp2,439,493$3.12M0.00%+66,697+2.8%Added
CM Management, LLC2,650,000$3.39M2.53%00.0%Unchanged