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Cytokinetics Inc

CYTK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001061983

In the last 90 days, Cytokinetics Inc insiders filed 0 open-market purchases and 16 sales; 482 institutions reported holding it in 13F filings for Q2 2026, worth $13.7B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Cytokinetics Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
431
+58 vs. Q3 2025
Shares held
139.5M
−1.24M (−0.9%) vs. Q3 2025
Total value
$8.87B
+$1.13B (+14.6%) vs. Q3 2025
New holders
106
143 more added
Sold out
48
134 more reduced

8 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CYTK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 431 institutions
Q1 2021: 193 institutionsQ2 2021: 191 institutionsQ3 2021: 211 institutionsQ4 2021: 250 institutionsQ1 2022: 240 institutionsQ2 2022: 263 institutionsQ3 2022: 276 institutionsQ4 2022: 278 institutionsQ1 2023: 263 institutionsQ2 2023: 253 institutionsQ3 2023: 251 institutionsQ4 2023: 347 institutionsQ1 2024: 390 institutionsQ2 2024: 344 institutionsQ3 2024: 348 institutionsQ4 2024: 347 institutionsQ1 2025: 356 institutionsQ2 2025: 312 institutionsQ3 2025: 381 institutionsQ4 2025: 431 institutionsQ1 2026: 441 institutionsQ2 2026: 482 institutions
Value heldQ4 2025: $8.87B
Q1 2021: $1.74BQ2 2021: $1.50BQ3 2021: $3.22BQ4 2021: $4.16BQ1 2022: $3.52BQ2 2022: $4.16BQ3 2022: $5.08BQ4 2022: $4.88BQ1 2023: $3.83BQ2 2023: $3.55BQ3 2023: $3.22BQ4 2023: $9.54BQ1 2024: $8.26BQ2 2024: $7.34BQ3 2024: $7.20BQ4 2024: $6.18BQ1 2025: $5.48BQ2 2025: $4.55BQ3 2025: $7.75BQ4 2025: $8.87BQ1 2026: $9.63BQ2 2026: $13.7B
Institutions holding CYTK and their total value by quarter
QuarterHoldersValue
Q2 2026482$13.7B
Q1 2026441$9.63B
Q4 2025431$8.87B
Q3 2025381$7.75B
Q2 2025312$4.55B
Q1 2025356$5.48B
Q4 2024347$6.18B
Q3 2024348$7.20B
Q2 2024344$7.34B
Q1 2024390$8.26B
Q4 2023347$9.54B
Q3 2023251$3.22B
Q2 2023253$3.55B
Q1 2023263$3.83B
Q4 2022278$4.88B
Q3 2022276$5.08B
Q2 2022263$4.16B
Q1 2022240$3.52B
Q4 2021250$4.16B
Q3 2021211$3.22B
Q2 2021191$1.50B
Q1 2021193$1.74B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Cytokinetics Inc; share changes are against Q3 2025.

Institutions holding CYTK in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Public Employees Retirement Association of Colorado10,552$670.0K0.00%00.0%Unchanged
Fred Alger Management, LLC10,563$671.2K0.00%−44,265−80.7%Reduced
DnB Asset Management AS11,079$704.0K0.00%+869+8.5%Added
M&T Bank Corp11,200$712.0K0.00%+5,188+86.3%Added
Nisa Investment Advisors, LLC11,463$728.4K0.00%−68−0.6%Reduced
Man Group plc11,587$736.2K0.00%+11,587New
Brinker Capital Investments, LLC11,633$739.2K0.01%+400+3.6%Added
State of Alaska, Department of Revenue11,945$758.0K0.01%−835−6.5%Reduced
LPL Financial LLC12,196$774.9K0.00%+995+8.9%Added
STRS Ohio12,300$781.5K0.00%+1,700+16.0%Added
Glenmede Trust Co NA12,770$811.4K0.00%+12,770New
Gallagher Fiduciary Advisors, LLC12,973$824.3K0.03%+1,182+10.0%Added
Kennedy Capital Management, Inc.13,183$837.6K0.02%+162+1.2%Added
NEOS Investment Management LLC13,278$843.7K0.00%−8,306−38.5%Reduced
Tema ETFs LLC13,278$843.7K0.07%−8,306−38.5%Reduced
Bank of Montreal13,292$844.6K0.00%+160+1.2%Added
Gabelli & Co Investment Advisers, Inc.13,578$862.7K0.13%−23,900−63.8%Reduced
Harvest Management LLC13,600$864.1K0.32%+1,000+7.9%Added
HighTower Advisors, LLC13,913$884.0K0.00%+1,113+8.7%Added
Toroso Investments, LLC13,988$888.8K0.00%+1,226+9.6%Added
Gabelli Funds LLC14,209$902.8K0.01%−20,550−59.1%Reduced
Cetera Investment Advisers14,269$906.7K0.00%−2,870−16.7%Reduced
Ami Asset Management Corp14,280$907.4K0.05%−1,003−6.6%Reduced
Atria Investments LLC14,370$913.1K0.01%+2,223+18.3%Added
Xponance, Inc.14,385$914.0K0.01%−2,328−13.9%Reduced
Marks Group Wealth Management, Inc14,566$925.5K0.09%+14,566New
Quadrant Capital Group LLC14,696$933.8K0.03%+5,448+58.9%Added
Walleye Capital LLC15,131$961.4K0.01%+10,928+260.0%Added
Dana Investment Advisors, Inc.15,376$977.0K0.03%−2,037−11.7%Reduced
Oak Ridge Investments LLC15,677$996.1K0.06%−389−2.4%Reduced
Vident Advisory, LLC16,455$1.05M0.01%+234+1.4%Added
Walleye Trading LLC16,658$1.06M0.02%+13,634+450.9%Added
Ethic Inc.16,840$1.07M0.02%+7,318+76.9%Added
Teacher Retirement System of Texas16,859$1.07M0.00%−10,987−39.5%Reduced
Victory Capital Management Inc17,543$1.11M0.00%−92−0.5%Reduced
J. Goldman & Co LP17,645$1.12M0.04%+3,140+21.6%Added
China Universal Asset Management Co., Ltd.19,923$1.27M0.10%−1,051−5.0%Reduced
JustInvest LLC20,725$1.32M0.01%+2,641+14.6%Added
J. Safra Sarasin Holding AG23,370$1.48M0.02%−1,097−4.5%Reduced
HRT Financial LP23,376$1.49M0.00%+23,376New
New Mexico Educational Retirement Board23,500$1.49M0.04%00.0%Unchanged
KLP Kapitalforvaltning AS24,300$1.54M0.01%+300+1.3%Added
Oregon Public Employees Retirement Fund24,415$1.55M0.02%+300+1.2%Added
Moore Capital Management, LP25,000$1.59M0.03%00.0%Unchanged
Great Lakes Advisors, LLC25,017$1.59M0.01%+144+0.6%Added
Natixis Advisors, L.P.26,250$1.67M0.00%+3,688+16.3%Added
Northwestern Mutual Investment Management Company, LLC27,355$1.74M0.02%+684+2.6%Added
Thrivent Financial for Lutherans27,532$1.75M0.00%+41+0.1%Added
Pacer Advisors, Inc.27,783$1.77M0.00%+12,043+76.5%Added
Caption Management, LLC27,999$1.78M0.08%−2,358−7.8%Reduced
State Board of Administration of Florida Retirement System28,486$1.81M0.00%00.0%Unchanged
State of Michigan Retirement System28,900$1.84M0.01%+400+1.4%Added
Comerica Bank28,970$1.84M0.01%−4,386−13.1%Reduced
Edgestream Partners, L.P.29,284$1.86M0.05%+29,284New
Birchview Capital, LP30,000$1.91M1.12%00.0%Unchanged
Mirae Asset Securities (USA) Inc.30,067$1.91M0.08%+30,067New
Royal Bank of Canada30,572$1.94M0.00%−37,621−55.2%Reduced
Commonwealth of Pennsylvania Public School Empls Retrmt Sys30,596$1.94M0.01%−114−0.4%Reduced
Guggenheim Capital LLC31,322$1.99M0.01%+440+1.4%Added
Police & Firemen's Retirement System of New Jersey31,502$2.00M0.02%−1,091−3.3%Reduced
Arizona State Retirement System31,926$2.03M0.01%−1,620−4.8%Reduced
Legato Capital Management LLC31,948$2.03M0.17%+14,345+81.5%Added
Ameritas Investment Partners, Inc.32,190$2.05M0.06%00.0%Unchanged
SG Americas Securities, LLC32,196$2.05M0.00%−19,201−37.4%Reduced
ProShare Advisors LLC32,219$2.05M0.00%+2,889+9.8%Added
Louisiana State Employees Retirement System33,300$2.12M0.04%00.0%Unchanged
Knott David M Jr34,000$2.16M1.00%+4,000+13.3%Added
Rock Springs Capital Management LP35,853$2.28M0.12%+35,853New
Zurcher Kantonalbank (Zurich Cantonalbank)36,414$2.31M0.00%+4,159+12.9%Added
State of Tennessee, Treasury Department37,506$2.37M0.01%−10,955−22.6%Reduced
Prelude Capital Management, LLC37,539$2.39M0.18%−3,938−9.5%Reduced
Quinn Opportunity Partners LLC38,082$2.42M0.10%−235,579−86.1%Reduced
State of New Jersey Common Pension Fund D38,799$2.47M0.01%−17,103−30.6%Reduced
Yousif Capital Management, LLC38,664$2.47M0.03%+25+0.1%Added
Profund Advisors LLC39,642$2.52M0.08%+13,712+52.9%Added
Prudential Financial Inc42,035$2.67M0.00%−1,291−3.0%Reduced
Rhenman & Partners Asset Management AB44,375$2.82M0.26%−210,875−82.6%Reduced
Nomura Asset Management International Inc.44,879$2.85M0.00%+44,879New
Pathstone Holdings, LLC45,399$2.88M0.01%+7,121+18.6%Added
New York State Common Retirement Fund46,175$2.93M0.00%−1,700−3.6%Reduced
Harvey Capital Management Inc46,810$2.97M0.63%+25,480+119.5%Added
IMC-Chicago, LLC47,657$3.03M0.05%+47,657New
Stifel Financial Corp47,971$3.05M0.00%+3,345+7.5%Added
Intech Investment Management LLC49,434$3.14M0.03%+10,775+27.9%Added
Quantinno Capital Management LP50,437$3.20M0.01%+22,000+77.4%Added
Amalgamated Bank50,630$3.22M0.02%−1,783−3.4%Reduced
Algert Global LLC51,310$3.26M0.05%−1,150−2.2%Reduced
Advisor Group Holdings, Inc.52,436$3.33M0.00%−2,297−4.2%Reduced
EFG International AG53,265$3.39M0.07%+53,265New
Dimensional Fund Advisors LP53,929$3.43M0.00%+2,670+5.2%Added
Universal- Beteiligungs- und Servicegesellschaft mbH54,278$3.45M0.01%+23,571+76.8%Added
Boothbay Fund Management, LLC56,453$3.59M0.09%−35,363−38.5%Reduced
Ironwood Investment Management LLC57,229$3.64M1.53%−103−0.2%Reduced
Mirae Asset Global ETFs Holdings Ltd.59,635$3.78M0.01%+143+0.2%Added
Tyro Capital Management LLC60,638$3.85M1.20%+60,638New
Envestnet Asset Management Inc62,733$3.99M0.00%+3,665+6.2%Added
Teachers Retirement System of the State of Kentucky62,789$3.99M0.03%+2,000+3.3%Added
ACT Capital Management, LLC64,500$4.10M3.31%+64,500New
Resolute Capital Asset Partners LLC65,000$4.13M2.00%+5,000+8.3%Added
Voya Investment Management LLC65,592$4.17M0.00%+10,948+20.0%Added