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Cue Biopharma, Inc.

CUE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001645460

In the last 90 days, Cue Biopharma, Inc. insiders filed 0 open-market purchases and 3 sales; 50 institutions reported holding it in 13F filings for Q2 2026, worth $52.2M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Cue Biopharma, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
49
−3 vs. Q3 2025
Shares held
21.8M
+3.76M (+20.8%) vs. Q3 2025
Total value
$6.67M
−$6.31M (−48.6%) vs. Q3 2025
New holders
8
8 more added
Sold out
11
11 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CUE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 49 institutions
Q1 2021: 89 institutionsQ2 2021: 90 institutionsQ3 2021: 89 institutionsQ4 2021: 91 institutionsQ1 2022: 100 institutionsQ2 2022: 76 institutionsQ3 2022: 64 institutionsQ4 2022: 61 institutionsQ1 2023: 63 institutionsQ2 2023: 78 institutionsQ3 2023: 75 institutionsQ4 2023: 80 institutionsQ1 2024: 77 institutionsQ2 2024: 75 institutionsQ3 2024: 50 institutionsQ4 2024: 55 institutionsQ1 2025: 49 institutionsQ2 2025: 47 institutionsQ3 2025: 52 institutionsQ4 2025: 49 institutionsQ1 2026: 57 institutionsQ2 2026: 50 institutions
Value heldQ4 2025: $6.67M
Q1 2021: $229.7MQ2 2021: $216.4MQ3 2021: $245.6MQ4 2021: $187.3MQ1 2022: $86.8MQ2 2022: $35.0MQ3 2022: $28.7MQ4 2022: $36.4MQ1 2023: $43.0MQ2 2023: $50.5MQ3 2023: $32.1MQ4 2023: $39.3MQ1 2024: $31.0MQ2 2024: $17.1MQ3 2024: $10.5MQ4 2024: $12.8MQ1 2025: $10.4MQ2 2025: $11.9MQ3 2025: $13.0MQ4 2025: $6.67MQ1 2026: $4.95MQ2 2026: $52.2M
Institutions holding CUE and their total value by quarter
QuarterHoldersValue
Q2 202650$52.2M
Q1 202657$4.95M
Q4 202549$6.67M
Q3 202552$13.0M
Q2 202547$11.9M
Q1 202549$10.4M
Q4 202455$12.8M
Q3 202450$10.5M
Q2 202475$17.1M
Q1 202477$31.0M
Q4 202380$39.3M
Q3 202375$32.1M
Q2 202378$50.5M
Q1 202363$43.0M
Q4 202261$36.4M
Q3 202264$28.7M
Q2 202276$35.0M
Q1 2022100$86.8M
Q4 202191$187.3M
Q3 202189$245.6M
Q2 202190$216.4M
Q1 202189$229.7M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Cue Biopharma, Inc.; share changes are against Q3 2025.

Institutions holding CUE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
JPMorgan Chase & Co4$10.00%−900−99.6%Reduced
IFP Advisors, Inc100$310.00%00.0%Unchanged
Armstrong Advisory Group, Inc120$370.00%00.0%Unchanged
Torren Management, LLC324$990.00%+324New
MAI Capital Management350$1070.00%00.0%Unchanged
Jones Financial Companies LLLP400$1220.00%+400New
BNP Paribas Arbitrage, SA415$1270.00%−275−39.9%Reduced
Advisor Group Holdings, Inc.680$2090.00%00.0%Unchanged
UMA Financial Services, Inc.1,006$3080.00%00.0%Unchanged
Tidemark, LLC1,500$4580.00%00.0%Unchanged
Golden State Wealth Management, LLC2,000$6110.00%00.0%Unchanged
Simplex Trading, LLC2,557$7800.00%−2,275−47.1%Reduced
Wells Fargo & Company2,563$7830.00%−17,014−86.9%Reduced
Newbridge Financial Services Group, Inc.3,000$9160.00%00.0%Unchanged
New Millennium Group LLC5,750$1.76K0.00%+5,750New
Gleason Group, Inc.6,000$1.83K0.00%00.0%Unchanged
Barclays PLC6,029$1.84K0.00%00.0%Unchanged
HighTower Advisors, LLC10,929$3.34K0.00%+10,929New
SeaCrest Wealth Management, LLC10,000$3.87K0.00%00.0%Unchanged
Goldman Sachs Group Inc14,371$4.39K0.00%−19−0.1%Reduced
Morgan Stanley18,594$5.68K0.00%−8,918−32.4%Reduced
Prevail Innovative Wealth Advisors, LLC18,987$5.80K0.00%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.20,000$6.00K0.00%00.0%Unchanged
HRT Financial LP20,863$6.00K0.00%+20,863New
GWM Advisors LLC20,000$6.11K0.00%00.0%Unchanged
Miramontes Capital, LLC26,041$7.95K0.00%+26,041New
Sigma Planning Corp41,050$12.5K0.00%−12,250−23.0%Reduced
LPL Financial LLC46,390$14.2K0.00%00.0%Unchanged
UBS Group AG46,848$14.3K0.00%−152,310−76.5%Reduced
Jane Street Group, LLC69,793$21.3K0.00%+69,793New
Northwestern Mutual Wealth Management Co79,500$24.3K0.00%00.0%Unchanged
Northern Trust Corp100,958$30.8K0.00%00.0%Unchanged
Chicago Partners Investment Group LLC85,937$32.7K0.00%00.0%Unchanged
Susquehanna International Group, LLP168,829$51.6K0.00%+2,373+1.4%Added
State Street Corp179,353$54.8K0.00%−10,400−5.5%Reduced
Bank of America Corp207,569$63.3K0.00%−116,952−36.0%Reduced
Renaissance Technologies LLC238,354$72.8K0.00%+11,290+5.0%Added
Stifel Financial Corp246,556$75.3K0.00%+50,000+25.4%Added
Advisory Research Inc257,225$78.6K0.01%00.0%Unchanged
Angeles Wealth Management, LLC310,000$94.7K0.01%+190,000+158.3%Added
Texas Capital Bank Wealth Management Services Inc440,670$134.6K0.01%+407,568+1,231.2%Added
BlackRock, Inc.449,162$137.2K0.00%00.0%Unchanged
Robertson Stephens Wealth Management, LLC478,500$146.1K0.00%00.0%Unchanged
Boothbay Fund Management, LLC704,297$215.1K0.01%+93,333+15.3%Added
Geode Capital Management, LLC803,291$245.4K0.00%+2,523+0.3%Added
Lion Point Capital, LP2,202,854$672.8K3.48%+2,202,854New
Vanguard Group Inc3,014,034$919.3K0.00%−25,288−0.8%Reduced
Catalytic Wealth RIA, LLC4,631,644$1.41M0.05%+1,200,000+35.0%Added
Bleichroeder LP6,819,164$2.08M0.37%00.0%Unchanged
Squarepoint Ops LLC0$00.00%−85,800−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−39,514−100.0%Sold out
Navalign, LLC0$00.00%−25,000−100.0%Sold out
Virtu Financial LLC0$00.00%−15,079−100.0%Sold out
XTX Topco Ltd0$00.00%−14,741−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−10,135−100.0%Sold out
Mather Group, LLC.0$00.00%−1,000−100.0%Sold out
Sunbelt Securities, Inc.0$00.00%−237−100.0%Sold out
Advisory Services Network, LLC0$00.00%−200−100.0%Sold out
Citigroup Inc0$00.00%−132−100.0%Sold out
SBI Securities Co., Ltd.0$00.00%−1−100.0%Sold out