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CRISPR Therapeutics AG

CRSP
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001674416

In the last 90 days, CRISPR Therapeutics AG insiders filed 0 open-market purchases and 2 sales; 525 institutions reported holding it in 13F filings for Q2 2026, worth $4.16B in total; ARK Invest is the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in CRISPR Therapeutics AG as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
482
+44 vs. Q3 2025
Shares held
76.5M
+4.26M (+5.9%) vs. Q3 2025
Total value
$4.01B
−$669.3M (−14.3%) vs. Q3 2025
New holders
96
149 more added
Sold out
52
129 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting CRSP on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 482 institutions
Q1 2021: 446 institutionsQ2 2021: 501 institutionsQ3 2021: 477 institutionsQ4 2021: 448 institutionsQ1 2022: 446 institutionsQ2 2022: 437 institutionsQ3 2022: 436 institutionsQ4 2022: 399 institutionsQ1 2023: 383 institutionsQ2 2023: 420 institutionsQ3 2023: 410 institutionsQ4 2023: 472 institutionsQ1 2024: 483 institutionsQ2 2024: 450 institutionsQ3 2024: 417 institutionsQ4 2024: 406 institutionsQ1 2025: 398 institutionsQ2 2025: 435 institutionsQ3 2025: 442 institutionsQ4 2025: 482 institutionsQ1 2026: 494 institutionsQ2 2026: 525 institutions
Value heldQ4 2025: $4.01B
Q1 2021: $5.20BQ2 2021: $6.57BQ3 2021: $4.53BQ4 2021: $3.25BQ1 2022: $3.10BQ2 2022: $3.35BQ3 2022: $3.70BQ4 2022: $2.26BQ1 2023: $2.54BQ2 2023: $3.07BQ3 2023: $2.50BQ4 2023: $3.48BQ1 2024: $4.10BQ2 2024: $3.22BQ3 2024: $2.81BQ4 2024: $2.54BQ1 2025: $2.20BQ2 2025: $3.52BQ3 2025: $4.68BQ4 2025: $4.01BQ1 2026: $3.67BQ2 2026: $4.16B
Institutions holding CRSP and their total value by quarter
QuarterHoldersValue
Q2 2026525$4.16B
Q1 2026494$3.67B
Q4 2025482$4.01B
Q3 2025442$4.68B
Q2 2025435$3.52B
Q1 2025398$2.20B
Q4 2024406$2.54B
Q3 2024417$2.81B
Q2 2024450$3.22B
Q1 2024483$4.10B
Q4 2023472$3.48B
Q3 2023410$2.50B
Q2 2023420$3.07B
Q1 2023383$2.54B
Q4 2022399$2.26B
Q3 2022436$3.70B
Q2 2022437$3.35B
Q1 2022446$3.10B
Q4 2021448$3.25B
Q3 2021477$4.53B
Q2 2021501$6.57B
Q1 2021446$5.20B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding CRISPR Therapeutics AG; share changes are against Q3 2025.

Institutions holding CRSP in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Federation des caisses Desjardins du Quebec2,323$121.8K0.00%+69+3.1%Added
HM Payson & Co2,320$121.7K0.00%00.0%Unchanged
MCF Advisors LLC2,187$114.7K0.01%+150+7.4%Added
Quantbot Technologies LP2,184$114.5K0.00%+2,184New
CIBC Private Wealth Group, LLC1,898$99.5K0.00%−183−8.8%Reduced
Bellevue Group AG1,880$98.6K0.00%+1,880New
GF Fund Management Co. Ltd.1,872$98.2K0.00%−2,767−59.6%Reduced
Harbour Investments, Inc.1,867$97.9K0.00%−7−0.4%Reduced
N.E.W. Advisory Services LLC1,667$87.4K0.01%−407−19.6%Reduced
Elkhorn Partners Limited Partnership1,660$87.0K0.05%−540−24.5%Reduced
TD Waterhouse Canada Inc.1,656$86.8K0.00%−59−3.4%Reduced
Spire Wealth Management1,568$82.2K0.00%00.0%Unchanged
Global Retirement Partners, LLC1,545$81.0K0.00%+567+58.0%Added
Signaturefd, LLC1,502$78.8K0.00%−70−4.5%Reduced
Daiwa Securities Group Inc.1,449$76.0K0.00%−196−11.9%Reduced
EFG International AG1,377$72.2K0.00%+1,377New
Pittenger & Anderson Inc1,325$69.5K0.00%+1,325New
Evelyn Partners Investment Management LLP1,300$68.2K0.00%00.0%Unchanged
Bayforest Capital Ltd1,296$68.0K0.05%+1,296New
IFP Advisors, Inc1,250$65.5K0.00%+288+29.9%Added
Strategic Advocates LLC1,195$63.6K0.02%+670+127.6%Added
Rakuten Securities, Inc.1,179$61.8K0.02%+811+220.4%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.1,118$59.0K0.00%+322+40.5%Added
Valley National Advisers Inc1,100$57.0K0.01%+100+10.0%Added
Itau Unibanco Holding S.A.1,060$55.6K0.00%+168+18.8%Added
Tradewinds Capital Management, LLC1,023$53.6K0.01%−370−26.6%Reduced
Highline Wealth Partners LLC1,000$52.4K0.01%00.0%Unchanged
NBC Securities, Inc.996$52.2K0.00%+88+9.7%Added
Darwin Advisors, LLC925$48.5K0.02%00.0%Unchanged
Larson Financial Group LLC882$46.3K0.00%+639+263.0%Added
Clearstead Advisors, LLC877$46.0K0.00%−40−4.4%Reduced
Los Angeles Capital Management LLC713$43.6K0.00%+713New
EMC Capital Management700$38.0K0.02%00.0%Unchanged
TFC Financial Management688$36.1K0.00%00.0%Unchanged
Twin Lakes Capital Management, LLC682$35.8K0.02%00.0%Unchanged
Oakworth Capital, Inc.646$33.9K0.00%+646New
Parallel Advisors, LLC619$32.5K0.00%+30+5.1%Added
Strategic Wealth Partners, Ltd.607$31.8K0.00%−243−28.6%Reduced
Costello Asset Management, INC600$31.5K0.01%−200−25.0%Reduced
Country Trust Bank600$31.5K0.00%00.0%Unchanged
Thurston, Springer, Miller, Herd & Titak, Inc.576$30.2K0.01%+382+196.9%Added
Rothschild Investment LLC562$29.5K0.00%+502+836.7%Added
Ramirez Asset Management, Inc.500$26.2K0.00%+500New
McGuire Capital Advisors Inc468$24.5K0.02%+468New
Altshuler Shaham Ltd420$22.0K0.00%+170+68.0%Added
Birchbrook, Inc.405$21.2K0.01%−645−61.4%Reduced
Manchester Capital Management LLC400$21.0K0.00%00.0%Unchanged
Newbridge Financial Services Group, Inc.400$21.0K0.00%+100+33.3%Added
Hollencrest Capital Management375$19.7K0.00%−250−40.0%Reduced
GAMMA Investing LLC366$19.2K0.00%+84+29.8%Added
SRS Capital Advisors, Inc.356$18.7K0.00%−442−55.4%Reduced
Aventura Private Wealth, LLC351$18.4K0.01%+351New
Bryn Mawr Trust Co350$18.4K0.00%00.0%Unchanged
Smartleaf Asset Management LLC316$16.8K0.00%+85+36.8%Added
Optiver Holding B.V.319$16.7K0.00%−185−36.7%Reduced
Geneos Wealth Management Inc.315$16.5K0.00%−100−24.1%Reduced
Sachetta, LLC305$16.0K0.01%00.0%Unchanged
Orion Capital Management LLC300$15.7K0.01%00.0%Unchanged
Murphy & Mullick Capital Management Corp285$14.9K0.01%00.0%Unchanged
Kemnay Advisory Services Inc.283$14.8K0.00%+283New
Tidemark, LLC280$14.7K0.00%−137−32.9%Reduced
Crewe Advisors LLC250$13.1K0.00%00.0%Unchanged
Align Financial, LLC13,110$13.1K0.01%+13,110New
Abound Wealth Management125$11.8K0.00%−9−6.7%Reduced
Ameriflex Group, Inc.225$11.8K0.01%+115+104.5%Added
Quattro Advisors LLC223$11.7K0.01%+223New
Colonial Trust Advisors209$11.0K0.00%−41−16.4%Reduced
Tucker Asset Management LLC207$10.9K0.00%+207New
BFSG, LLC206$10.8K0.00%00.0%Unchanged
Operose Advisors LLC202$10.6K0.00%00.0%Unchanged
WealthCollab, LLC200$10.5K0.00%00.0%Unchanged
Flagship Wealth Advisors, LLC200$10.5K0.00%00.0%Unchanged
Bank of Jackson Hole Trust200$10.5K0.00%00.0%Unchanged
Chesapeake Asset Management LLC200$10.5K0.01%+200New
Adkins Seale Capital Management LLC200$10.5K0.01%+200New
Covestor Ltd170$9.00K0.00%−575−77.2%Reduced
CX Institutional174$9.00K0.00%00.0%Unchanged
Blue Bell Private Wealth Management, LLC163$8.55K0.00%+41+33.6%Added
Pinnacle Wealth Planning Services, Inc.161$8.44K0.00%+161New
Quadrant Capital Group LLC158$8.29K0.00%−36−18.6%Reduced
Sound Income Strategies, LLC152$8.13K0.00%+25+19.7%Added
GPS Wealth Strategies Group, LLC152$7.97K0.01%−337−68.9%Reduced
Elyxium Wealth, LLC152$7.97K0.00%+152New
Bogart Wealth, LLC150$7.87K0.00%−500−76.9%Reduced
Millstone Evans Group, LLC150$7.87K0.00%+75+100.0%Added
SHP Wealth Management145$7.60K0.00%+145New
Basecamp Wealth Advisors LLC143$7.50K0.00%+143New
CWM Advisors, LLC139$7.28K0.00%+139New
Front Row Advisors LLC134$7.03K0.00%00.0%Unchanged
CoreCap Advisors, LLC118$6.19K0.00%00.0%Unchanged
Asset Dedication, LLC115$6.03K0.00%00.0%Unchanged
Godsey & Gibb Associates108$5.66K0.00%+108New
Financial Consulate, Inc105$5.51K0.00%00.0%Unchanged
Cornerstone Planning Group LLC100$5.37K0.00%+100New
Atlantic Trust, LLC102$5.35K0.00%00.0%Unchanged
Danske Bank A/S100$5.24K0.00%00.0%Unchanged
First United Bank Trust100$5.24K0.00%00.0%Unchanged
Wolff Wiese Magana LLC100$5.24K0.00%00.0%Unchanged
Financial Freedom, LLC100$5.24K0.00%00.0%Unchanged
Raelipskie Partnership100$5.24K0.00%00.0%Unchanged