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AstraZeneca PLC

AZN
Exchange
NYSE
Industry
Pharmaceutical Preparations
SEC CIK
0000901832

In the last 90 days, AstraZeneca PLC insiders filed 1 open-market purchase and 0 sales; 1,511 institutions reported holding it in 13F filings for Q2 2026, worth $151.3B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in AstraZeneca PLC as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,410
+146 vs. Q3 2025
Shares held
504.2M
+11.4M (+2.3%) vs. Q3 2025
Total value
$46.4B
+$8.57B (+22.7%) vs. Q3 2025
New holders
266
501 more added
Sold out
120
412 more reduced

28 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AZN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 1,410 institutions
Q1 2021: 757 institutionsQ2 2021: 772 institutionsQ3 2021: 911 institutionsQ4 2021: 952 institutionsQ1 2022: 984 institutionsQ2 2022: 1,019 institutionsQ3 2022: 968 institutionsQ4 2022: 1,063 institutionsQ1 2023: 1,057 institutionsQ2 2023: 1,093 institutionsQ3 2023: 1,075 institutionsQ4 2023: 1,131 institutionsQ1 2024: 1,141 institutionsQ2 2024: 1,213 institutionsQ3 2024: 1,230 institutionsQ4 2024: 1,222 institutionsQ1 2025: 1,251 institutionsQ2 2025: 1,223 institutionsQ3 2025: 1,292 institutionsQ4 2025: 1,410 institutionsQ1 2026: 1,388 institutionsQ2 2026: 1,511 institutions
Value heldQ4 2025: $46.4B
Q1 2021: $20.4BQ2 2021: $26.1BQ3 2021: $31.1BQ4 2021: $29.4BQ1 2022: $34.3BQ2 2022: $34.9BQ3 2022: $28.3BQ4 2022: $34.2BQ1 2023: $35.0BQ2 2023: $35.4BQ3 2023: $33.7BQ4 2023: $33.2BQ1 2024: $33.8BQ2 2024: $39.0BQ3 2024: $39.1BQ4 2024: $33.7BQ1 2025: $37.0BQ2 2025: $34.7BQ3 2025: $37.9BQ4 2025: $46.4BQ1 2026: $148.4BQ2 2026: $151.3B
Institutions holding AZN and their total value by quarter
QuarterHoldersValue
Q2 20261,511$151.3B
Q1 20261,388$148.4B
Q4 20251,410$46.4B
Q3 20251,292$37.9B
Q2 20251,223$34.7B
Q1 20251,251$37.0B
Q4 20241,222$33.7B
Q3 20241,230$39.1B
Q2 20241,213$39.0B
Q1 20241,141$33.8B
Q4 20231,131$33.2B
Q3 20231,075$33.7B
Q2 20231,093$35.4B
Q1 20231,057$35.0B
Q4 20221,063$34.2B
Q3 2022968$28.3B
Q2 20221,019$34.9B
Q1 2022984$34.3B
Q4 2021952$29.4B
Q3 2021911$31.1B
Q2 2021772$26.1B
Q1 2021757$20.4B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding AstraZeneca PLC; share changes are against Q3 2025.

Institutions holding AZN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Capital International Investors14,521,078$1.34B0.21%−10,531,442−42.0%Reduced
Invesco Ltd.17,520,754$1.61B0.15%+13,324,457+317.5%Added
Franklin Resources Inc20,157,744$1.85B0.45%+445,014+2.3%Added
Fisher Asset Management, LLC21,601,433$1.99B0.68%+438,709+2.1%Added
FMR LLC21,848,855$2.01B0.10%+162,535+0.7%Added
Wellington Management Group LLP22,828,246$2.10B0.37%−9,471,315−29.3%Reduced
Bank of America Corp26,356,351$2.42B0.18%−6,276,788−19.2%Reduced
Primecap Management Co36,915,261$3.39B2.57%−2,942,710−7.4%Reduced
Price T Rowe Associates Inc48,643,827$4.47B0.48%−480,649−1.0%Reduced
FNY Investment Advisers, LLC200––00.0%Unchanged
Qube Research & Technologies Ltd0$00.00%−774,403−100.0%Sold out
Bridgewater Associates, LP0$00.00%−462,859−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−444,874−100.0%Sold out
Macquarie Group Ltd0$00.00%−346,576−100.0%Sold out
Beck Bode, LLC0$00.00%−223,543−100.0%Sold out
Jane Street Group, LLC0$00.00%−223,070−100.0%Sold out
Squarepoint Ops LLC0$00.00%−180,473−100.0%Sold out
HRT Financial LP0$00.00%−171,635−100.0%Sold out
Foresight Group Ltd Liability Partnership0$00.00%−171,086−100.0%Sold out
Tang Capital Management LLC0$00.00%−150,000−100.0%Sold out
Zevin Asset Management LLC0$00.00%−143,346−100.0%Sold out
Howe & Rusling Inc0$00.00%−117,593−100.0%Sold out
Oppenheimer Asset Management Inc.0$00.00%−116,460−100.0%Sold out
Zimmer Partners, LP0$00.00%−108,200−100.0%Sold out
Scharf Investments, LLC0$00.00%−92,464−100.0%Sold out
Orca Wealth Management, LLC0$00.00%−68,978−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−66,643−100.0%Sold out
PFM Health Sciences, LP0$00.00%−61,795−100.0%Sold out
Simplex Trading, LLC0$00.00%−59,483−100.0%Sold out
Americana Partners, LLC0$00.00%−49,833−100.0%Sold out
Longfellow Investment Management Co LLC0$00.00%−49,765−100.0%Sold out
Guardian Partners Inc.0$00.00%−44,581−100.0%Sold out
IMC-Chicago, LLC0$00.00%−41,505−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−39,286−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−38,817−100.0%Sold out
My Personal CFO, LLC0$00.00%−38,411−100.0%Sold out
Aurora Investment Counsel0$00.00%−36,425−100.0%Sold out
Horizon Investments, LLC0$00.00%−30,649−100.0%Sold out
Oppenheimer & Co Inc0$00.00%−29,738−100.0%Sold out
Empowered Funds, LLC0$00.00%−28,199−100.0%Sold out
Level Four Advisory Services, LLC0$00.00%−27,513−100.0%Sold out
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors0$00.00%−25,596−100.0%Sold out
Engineers Gate Manager LP0$00.00%−25,377−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−25,000−100.0%Sold out
Optiver Holding B.V.0$00.00%−23,275−100.0%Sold out
Generali Investments CEE, investicni spolecnost, a.s.0$00.00%−21,100−100.0%Sold out
NJ State Employees Deferred Compensation Plan0$00.00%−19,118−100.0%Sold out
Pitcairn Co0$00.00%−16,184−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−13,912−100.0%Sold out
Capitolis Liquid Global Markets LLC0$00.00%−13,900−100.0%Sold out
Legacy Financial Advisors, Inc.0$00.00%−13,809−100.0%Sold out
Sanders Morris Harris LLC0$00.00%−12,379−100.0%Sold out
Marietta Investment Partners LLC0$00.00%−12,184−100.0%Sold out
Saranac Partners Ltd0$00.00%−5,817−100.0%Sold out
Sittner & Nelson, LLC0$00.00%−11,225−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−10,841−100.0%Sold out
Whalen Wealth Management Inc.0$00.00%−9,719−100.0%Sold out
Riverview Capital Advisers, LLC0$00.00%−9,491−100.0%Sold out
Arete Wealth Advisors, LLC0$00.00%−8,694−100.0%Sold out
HBK Sorce Advisory LLC0$00.00%−7,785−100.0%Sold out
Omers Administration Corp0$00.00%−7,600−100.0%Sold out
Coastline Trust Co0$00.00%−7,570−100.0%Sold out
Howland Capital Management LLC0$00.00%−7,000−100.0%Sold out
Bradley Foster & Sargent Inc0$00.00%−6,882−100.0%Sold out
Prospector Partners LLC0$00.00%−6,877−100.0%Sold out
Brighton Jones LLC0$00.00%−6,857−100.0%Sold out
CenterStar Asset Management, LLC0$00.00%−6,679−100.0%Sold out
Change Path, LLC0$00.00%−6,140−100.0%Sold out
Legacy Capital Group California, Inc.0$00.00%−5,287−100.0%Sold out
Pine Valley Investments Ltd Liability Co0$00.00%−5,036−100.0%Sold out
Blue Barn Wealth, LLC0$00.00%−4,904−100.0%Sold out
GM Advisory Group, Inc.0$00.00%−4,845−100.0%Sold out
Astoria Portfolio Advisors LLC.0$00.00%−4,339−100.0%Sold out
Consolidated Portfolio Review Corp0$00.00%−4,688−100.0%Sold out
Advisors Preferred, LLC0$00.00%−4,223−100.0%Sold out
NorthRock Partners, LLC0$00.00%−4,466−100.0%Sold out
Jain Global LLC0$00.00%−4,450−100.0%Sold out
Sonoma Allocations LLC0$00.00%−3,593−100.0%Sold out
Blueshift Asset Management, LLC0$00.00%−3,883−100.0%Sold out
MidWestOne Financial Group, Inc.0$00.00%−3,582−100.0%Sold out
Sig Brokerage, LP0$00.00%−3,382−100.0%Sold out
Beaumont Financial Advisors, LLC0$00.00%−3,251−100.0%Sold out
New England Professional Planning Group Inc.0$00.00%−3,140−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−3,129−100.0%Sold out
Advisor OS, LLC0$00.00%−2,962−100.0%Sold out
Accuvest Global Advisors0$00.00%−2,945−100.0%Sold out
BKD Wealth Advisors, LLC0$00.00%−2,884−100.0%Sold out
MQS Management LLC0$00.00%−2,855−100.0%Sold out
FineMark National Bank & Trust0$00.00%−2,845−100.0%Sold out
Founders Financial Alliance, LLC0$00.00%−2,759−100.0%Sold out
Donaldson Capital Management, LLC0$00.00%−2,736−100.0%Sold out
Virtu Financial LLC0$00.00%−2,717−100.0%Sold out
Penserra Capital Management LLC0$00.00%−1,846−100.0%Sold out
Rise Advisors, LLC0$00.00%−1,643−100.0%Sold out
Palisade Asset Management, LLC0$00.00%−1,591−100.0%Sold out
Salem Investment Counselors Inc0$00.00%−1,413−100.0%Sold out
Cloud Capital Management, LLC0$00.00%−1,205−100.0%Sold out
Montag A & Associates Inc0$00.00%−742−100.0%Sold out
Alpine Bank Wealth Management0$00.00%−700−100.0%Sold out
Hollencrest Capital Management0$00.00%−600−100.0%Sold out