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AstraZeneca PLC

AZN
Exchange
NYSE
Industry
Pharmaceutical Preparations
SEC CIK
0000901832

In the last 90 days, AstraZeneca PLC insiders filed 1 open-market purchase and 0 sales; 1,511 institutions reported holding it in 13F filings for Q2 2026, worth $151.3B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in AstraZeneca PLC as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,410
+146 vs. Q3 2025
Shares held
504.2M
+11.4M (+2.3%) vs. Q3 2025
Total value
$46.4B
+$8.57B (+22.7%) vs. Q3 2025
New holders
266
501 more added
Sold out
120
412 more reduced

28 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AZN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 1,410 institutions
Q1 2021: 757 institutionsQ2 2021: 772 institutionsQ3 2021: 911 institutionsQ4 2021: 952 institutionsQ1 2022: 984 institutionsQ2 2022: 1,019 institutionsQ3 2022: 968 institutionsQ4 2022: 1,063 institutionsQ1 2023: 1,057 institutionsQ2 2023: 1,093 institutionsQ3 2023: 1,075 institutionsQ4 2023: 1,131 institutionsQ1 2024: 1,141 institutionsQ2 2024: 1,213 institutionsQ3 2024: 1,230 institutionsQ4 2024: 1,222 institutionsQ1 2025: 1,251 institutionsQ2 2025: 1,223 institutionsQ3 2025: 1,292 institutionsQ4 2025: 1,410 institutionsQ1 2026: 1,389 institutionsQ2 2026: 1,511 institutions
Value heldQ4 2025: $46.4B
Q1 2021: $20.4BQ2 2021: $26.1BQ3 2021: $31.1BQ4 2021: $29.4BQ1 2022: $34.3BQ2 2022: $34.9BQ3 2022: $28.3BQ4 2022: $34.2BQ1 2023: $35.0BQ2 2023: $35.4BQ3 2023: $33.7BQ4 2023: $33.2BQ1 2024: $33.8BQ2 2024: $39.0BQ3 2024: $39.1BQ4 2024: $33.7BQ1 2025: $37.0BQ2 2025: $34.7BQ3 2025: $37.9BQ4 2025: $46.4BQ1 2026: $148.4BQ2 2026: $151.3B
Institutions holding AZN and their total value by quarter
QuarterHoldersValue
Q2 20261,511$151.3B
Q1 20261,389$148.4B
Q4 20251,410$46.4B
Q3 20251,292$37.9B
Q2 20251,223$34.7B
Q1 20251,251$37.0B
Q4 20241,222$33.7B
Q3 20241,230$39.1B
Q2 20241,213$39.0B
Q1 20241,141$33.8B
Q4 20231,131$33.2B
Q3 20231,075$33.7B
Q2 20231,093$35.4B
Q1 20231,057$35.0B
Q4 20221,063$34.2B
Q3 2022968$28.3B
Q2 20221,019$34.9B
Q1 2022984$34.3B
Q4 2021952$29.4B
Q3 2021911$31.1B
Q2 2021772$26.1B
Q1 2021757$20.4B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding AstraZeneca PLC; share changes are against Q3 2025.

Institutions holding AZN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Price T Rowe Associates Inc48,643,827$4.47B0.48%−480,649−1.0%Reduced
Primecap Management Co36,915,261$3.39B2.57%−2,942,710−7.4%Reduced
Bank of America Corp26,356,351$2.42B0.18%−6,276,788−19.2%Reduced
Wellington Management Group LLP22,828,246$2.10B0.37%−9,471,315−29.3%Reduced
FMR LLC21,848,855$2.01B0.10%+162,535+0.7%Added
Fisher Asset Management, LLC21,601,433$1.99B0.68%+438,709+2.1%Added
Franklin Resources Inc20,157,744$1.85B0.45%+445,014+2.3%Added
Invesco Ltd.17,520,754$1.61B0.15%+13,324,457+317.5%Added
Capital International Investors14,521,078$1.34B0.21%−10,531,442−42.0%Reduced
Goldman Sachs Group Inc14,411,321$1.32B0.19%+739,572+5.4%Added
Sanders Capital, LLC14,139,408$1.30B1.50%+80,726+0.6%Added
Morgan Stanley13,878,726$1.28B0.08%+432,939+3.2%Added
Ameriprise Financial Inc10,495,599$965.7M0.22%+4,788,038+83.9%Added
CIBC Private Wealth Group, LLC8,081,817$743.0M1.26%−72,331−0.9%Reduced
Dimensional Fund Advisors LP6,621,662$608.9M0.13%−184,234−2.7%Reduced
Citigroup Inc6,154,760$565.8M0.39%+2,331,890+61.0%Added
BlackRock, Inc.6,113,037$562.0M0.01%+308,683+5.3%Added
Arrowstreet Capital, Limited Partnership5,547,597$510.0M0.30%+4,697,895+552.9%Added
Neuberger Berman Group LLC4,959,858$456.0M0.34%−107,675−2.1%Reduced
Northern Trust Corp4,756,686$437.3M0.06%+130,245+2.8%Added
Raymond James Financial Inc4,418,771$406.9M0.13%+18,502+0.4%Added
Holocene Advisors, LP4,332,123$398.3M0.84%−1,797,071−29.3%Reduced
Fayez Sarofim & Co4,258,640$391.5M0.94%+364,203+9.4%Added
Boston Partners4,229,792$389.4M0.40%−1,017,657−19.4%Reduced
Clearbridge Investments, LLC4,204,564$386.5M0.31%−507,493−10.8%Reduced
Envestnet Asset Management Inc4,051,646$372.5M0.11%+204,979+5.3%Added
Swedbank AB3,989,339$366.7M0.35%−375,119−8.6%Reduced
JPMorgan Chase & Co3,746,985$344.5M0.02%−1,077,087−22.3%Reduced
Harris Associates L PSuperinvestorHarris Associates (Oakmark)3,729,731$342.9M0.44%+3,729,731New
American Century Companies Inc3,442,805$316.5M0.16%+1,255,755+57.4%Added
Royal Bank of Canada3,365,329$309.4M0.05%−23,342−0.7%Reduced
Jennison Associates LLC3,362,846$309.1M0.19%−322,818−8.8%Reduced
Bank of Montreal3,277,737$301.3M0.12%−200,377−5.8%Reduced
Wells Fargo & Company3,102,852$285.2M0.06%−171,819−5.2%Reduced
UBS Group AG2,878,796$264.6M0.05%+394,521+15.9%Added
Barclays PLC2,745,603$252.4M0.10%+2,058,077+299.3%Added
WCM Investment Management, LLC2,662,619$246.3M0.51%−1,1400.0%Reduced
Voya Investment Management LLC2,672,165$245.5M0.24%+772,663+40.7%Added
Millennium Management LLC2,396,943$220.4M0.16%+169,598+7.6%Added
National Bank of Canada2,236,063$205.6M0.21%+1,116,871+99.8%Added
Two Sigma Investments, LP2,180,476$200.5M0.30%+1,662,781+321.2%Added
Acadian Asset Management LLC2,178,578$200.2M0.33%+49,237+2.3%Added
Natixis Advisors, L.P.2,053,511$188.8M0.27%−46,879−2.2%Reduced
Point72 Asset Management, L.P.1,852,741$170.3M0.27%+1,283,372+225.4%Added
Bank Julius Baer & Co. Ltd, Zurich1,806,877$166.3M0.46%+1,790,874+11,190.9%Added
Alyeska Investment Group, L.P.1,726,795$158.7M0.45%+1,184,630+218.5%Added
Saturna Capital CORP1,635,207$150.3M1.99%+2120.0%Added
Sofinnova Investments, Inc.1,632,334$150.1M6.47%+808,401+98.1%Added
Allspring Global Investments Holdings, LLC1,628,771$149.1M0.24%+1,437,253+750.5%Added
Manning & Napier Advisors LLC1,541,423$142.6M1.85%−220,770−12.5%Reduced
Crawford Investment Counsel Inc1,538,963$141.5M2.36%−27,110−1.7%Reduced
Truist Financial Corp1,538,680$141.5M0.19%+537,908+53.7%Added
Mackenzie Financial Corp1,484,312$137.0M0.16%+915,711+161.0%Added
Connor, Clark & Lunn Investment Management Ltd.1,421,698$130.7M0.34%+1,379,889+3,300.5%Added
LMR Partners LLP1,416,898$130.3M1.25%+80,000+6.0%Added
Alliancebernstein L.P.1,347,232$123.9M0.04%−53,121−3.8%Reduced
Lazard Asset Management LLC1,337,216$122.9M0.21%+2,656+0.2%Added
Fred Alger Management, LLC1,318,719$121.2M0.48%+1,263,721+2,297.8%Added
Clark Capital Management Group, Inc.1,293,169$118.9M0.73%−1,315−0.1%Reduced
Stifel Financial Corp1,288,855$118.5M0.11%+112,092+9.5%Added
Norges Bank1,276,181$117.3M0.01%+1,276,181New
Two Sigma Advisers, LP1,272,600$117.0M0.23%+1,272,600New
Parnassus Investments1,237,719$113.8M0.30%−55,285−4.3%Reduced
Janus Henderson Group PLC1,207,156$111.0M0.05%−92,730−7.1%Reduced
LPL Financial LLC1,152,872$106.0M0.03%+84,348+7.9%Added
Principal Financial Group Inc1,125,252$103.4M0.05%−49,609−4.2%Reduced
TD Asset Management Inc1,112,841$102.3M0.08%+23,229+2.1%Added
Nicholas Company, Inc.1,083,854$99.6M1.75%−44,150−3.9%Reduced
Balyasny Asset Management LLC1,078,380$99.1M0.19%+402,218+59.5%Added
Bank of New York Mellon Corp1,032,000$94.9M0.02%+25,833+2.6%Added
Causeway Capital Management LLC1,010,898$92.9M1.28%−56,473−5.3%Reduced
BNP Paribas Arbitrage, SA984,405$90.5M0.06%−637,899−39.3%Reduced
Erste Asset Management GmbH972,748$89.5M0.75%−9,900−1.0%Reduced
SEI Investments Co966,235$88.8M0.09%+248,961+34.7%Added
HighTower Advisors, LLC965,247$88.7M0.10%+7,012+0.7%Added
ProShare Advisors LLC932,624$85.7M0.15%+277,765+42.4%Added
Capital World Investors914,079$84.1M0.01%−179,541−16.4%Reduced
First Trust Advisors LP871,656$80.1M0.06%−134,094−13.3%Reduced
State Street Corp842,157$77.4M0.00%−124,992−12.9%Reduced
Standard Life Aberdeen plc841,574$77.4M0.12%+41,357+5.2%Added
Citadel Advisors LLC840,134$77.2M0.05%−2,746,151−76.6%Reduced
Epoch Investment Partners, Inc.827,094$76.0M0.43%−213,033−20.5%Reduced
Phoenix Holdings Ltd.804,400$73.9M0.80%−2600.0%Reduced
Assenagon Asset Management S.A.787,084$72.4M0.11%+188,730+31.5%Added
ZWJ Investment Counsel Inc763,309$70.2M2.53%−7,973−1.0%Reduced
Harvest Portfolios Group Inc.754,813$69.4M1.21%−39,131−4.9%Reduced
Woodley Farra Manion Portfolio Management Inc747,560$68.7M3.27%−5,254−0.7%Reduced
Russell Investments Group, Ltd.738,538$67.9M0.07%−124,734−14.4%Reduced
Mariner, LLC690,319$63.5M0.08%+17,800+2.6%Added
Rockefeller Capital Management L.P.654,439$60.2M0.11%−147,931−18.4%Reduced
Van Eck Associates Corp613,411$56.4M0.05%+302,972+97.6%Added
1832 Asset Management L.P.579,050$53.2M0.07%+551,551+2,005.7%Added
Cerity Partners LLC573,405$52.7M0.08%+33,802+6.3%Added
Ontario Teachers Pension Plan Board572,652$52.6M1.17%−245,228−30.0%Reduced
Cidel Asset Management Inc562,431$51.7M3.66%−35,878−6.0%Reduced
Foresight Global Investors, Inc.290,672$51.0M24.01%+47,495+19.5%Added
Hardman Johnston Global Advisors LLC546,923$50.3M2.40%−14,659−2.6%Reduced
Nuveen, LLC542,568$49.9M0.01%+18,056+3.4%Added
Deutsche Bank AG530,691$48.8M0.02%+181,366+51.9%Added
Thornburg Investment Management Inc505,985$46.5M0.59%−4,962−1.0%Reduced