Aytu Biopharma, Inc
AYTU- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001385818
No open-market purchases or sales by Aytu Biopharma, Inc insiders were filed in the last 90 days; 38 institutions reported holding it in 13F filings for Q2 2026, worth $8.25M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Aytu Biopharma, Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 37
- +1 vs. Q4 2025
- Shares held
- 3.90M
- +430.4K (+12.4%) vs. Q4 2025
- Total value
- $10.7M
- +$1.62M (+18.0%) vs. Q4 2025
- New holders
- 6
- 9 more added
- Sold out
- 5
- 5 more reduced
3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AYTU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 38 | $8.25M |
| Q1 2026 | 37 | $10.7M |
| Q4 2025 | 39 | $9.81M |
| Q3 2025 | 33 | $6.73M |
| Q2 2025 | 32 | $7.45M |
| Q1 2025 | 31 | $2.49M |
| Q4 2024 | 29 | $3.19M |
| Q3 2024 | 24 | $4.81M |
| Q2 2024 | 27 | $5.99M |
| Q1 2024 | 27 | $5.46M |
| Q4 2023 | 22 | $5.02M |
| Q3 2023 | 22 | $4.65M |
| Q2 2023 | 21 | $2.73M |
| Q1 2023 | 21 | $1.21M |
| Q4 2022 | 42 | $1.52M |
| Q3 2022 | 53 | $1.64M |
| Q2 2022 | 41 | $2.50M |
| Q1 2022 | 44 | $6.02M |
| Q4 2021 | 46 | $5.10M |
| Q3 2021 | 49 | $12.2M |
| Q2 2021 | 61 | $26.0M |
| Q1 2021 | 72 | $48.4M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Aytu Biopharma, Inc; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 1,086,812 | $2.97M | 0.19% | 00.0% | Unchanged |
| Stonepine Capital Management, LLC | 792,289 | $2.16M | 1.90% | −21,415−2.6% | Reduced |
| AWM Investment Company, Inc. | 619,574 | $1.69M | 0.19% | 00.0% | Unchanged |
| Diadema Partners LP | 353,077 | $963.9K | 0.40% | +47,289+15.5% | Added |
| Vanguard Capital Management LLC | 261,146 | $712.9K | 0.00% | +261,146 | New |
| Crown Advisors Management, Inc. | 145,000 | $395.0K | 0.26% | +145,000 | New |
| Two Sigma Investments, LP | 121,973 | $333.0K | 0.00% | +14,840+13.9% | Added |
| Renaissance Technologies LLC | 93,723 | $255.9K | 0.00% | +4,100+4.6% | Added |
| Persistent Asset Partners Ltd | 92,897 | $253.6K | 0.10% | +13,482+17.0% | Added |
| Geode Capital Management, LLC | 92,636 | $252.9K | 0.00% | +18,539+25.0% | Added |
| Vanguard Fiduciary Trust Co | 47,048 | $128.4K | 0.00% | +47,048 | New |
| Dimensional Fund Advisors LP | 43,585 | $119.0K | 0.00% | +8,222+23.3% | Added |
| Citadel Advisors LLC | 36,841 | $100.6K | 0.00% | +21,290+136.9% | Added |
| Bellevue Asset Management, LLC | 25,013 | $68.3K | 0.03% | 00.0% | Unchanged |
| BlackRock, Inc. | 22,793 | $62.2K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 21,582 | $58.9K | 0.00% | −4,278−16.5% | Reduced |
| Northern Trust Corp | 19,169 | $52.3K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 10,237 | $27.0K | 0.00% | 00.0% | Unchanged |
| Daytona Street Capital LLC | 10,000 | $26.8K | 0.02% | 00.0% | Unchanged |
| MAI Capital Management | 3,575 | $9.76K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 1,663 | $4.54K | 0.00% | −1,386−45.5% | Reduced |
| Tower Research Capital LLC (TRC) | 1,564 | $4.27K | 0.00% | −149−8.7% | Reduced |
| Advisor Group Holdings, Inc. | 462 | $1.26K | 0.00% | +2+0.4% | Added |
| JPMorgan Chase & Co | 154 | $405 | 0.00% | +154 | New |
| Wells Fargo & Company | 127 | $347 | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 125 | $341 | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 37 | $101 | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 23 | $63 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 21 | $57 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 11 | $30 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 10 | $27 | 0.00% | +10 | New |
| Vision Financial Markets LLC | 2 | $6 | 0.00% | 00.0% | Unchanged |
| Caitong International Asset Management Co., Ltd | 2 | $5 | 0.00% | +2 | New |
| Jones Financial Companies LLLP | 1 | $3 | 0.00% | 00.0% | Unchanged |
| FNY Investment Advisers, LLC | 90 | $0 | 0.00% | −31,510−99.7% | Reduced |
| Royal Bank of Canada | 36 | $0 | 0.00% | +11+44.0% | Added |
| TSFG, LLC | 1 | $0 | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −42,500−100.0% | Sold out |
| DRW Securities, LLC | 0 | $0 | 0.00% | −29,368−100.0% | Sold out |
| Sentinus, LLC | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Bank of America Corp | 0 | $0 | 0.00% | −85−100.0% | Sold out |
| Citigroup Inc | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Perritt Capital Management Inc | – | – | – | – | Not filed |
| CIBC Private Wealth Group, LLC | – | – | – | – | Not filed |