Aytu Biopharma, Inc
AYTU- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001385818
No open-market purchases or sales by Aytu Biopharma, Inc insiders were filed in the last 90 days; 38 institutions reported holding it in 13F filings for Q2 2026, worth $8.25M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Aytu Biopharma, Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 39
- +6 vs. Q3 2025
- Shares held
- 3.77M
- +191.1K (+5.3%) vs. Q3 2025
- Total value
- $9.81M
- +$3.07M (+45.7%) vs. Q3 2025
- New holders
- 9
- 9 more added
- Sold out
- 3
- 6 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting AYTU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 38 | $8.25M |
| Q1 2026 | 37 | $10.7M |
| Q4 2025 | 39 | $9.81M |
| Q3 2025 | 33 | $6.73M |
| Q2 2025 | 32 | $7.45M |
| Q1 2025 | 31 | $2.49M |
| Q4 2024 | 29 | $3.19M |
| Q3 2024 | 24 | $4.81M |
| Q2 2024 | 27 | $5.99M |
| Q1 2024 | 27 | $5.46M |
| Q4 2023 | 22 | $5.02M |
| Q3 2023 | 22 | $4.65M |
| Q2 2023 | 21 | $2.73M |
| Q1 2023 | 21 | $1.21M |
| Q4 2022 | 42 | $1.52M |
| Q3 2022 | 53 | $1.64M |
| Q2 2022 | 41 | $2.50M |
| Q1 2022 | 44 | $6.02M |
| Q4 2021 | 46 | $5.10M |
| Q3 2021 | 49 | $12.2M |
| Q2 2021 | 61 | $26.0M |
| Q1 2021 | 72 | $48.4M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Aytu Biopharma, Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Nantahala Capital Management, LLC | 1,086,812 | $2.83M | 0.17% | 00.0% | Unchanged |
| Stonepine Capital Management, LLC | 813,704 | $2.12M | 1.67% | −78,151−8.8% | Reduced |
| AWM Investment Company, Inc. | 619,574 | $1.61M | 0.16% | 00.0% | Unchanged |
| Diadema Partners LP | 305,788 | $795.0K | 0.47% | +33,118+12.1% | Added |
| Vanguard Group Inc | 278,583 | $724.3K | 0.00% | 00.0% | Unchanged |
| Two Sigma Investments, LP | 107,133 | $278.5K | 0.00% | +38,397+55.9% | Added |
| Renaissance Technologies LLC | 89,623 | $233.0K | 0.00% | −5,500−5.8% | Reduced |
| Persistent Asset Partners Ltd | 79,415 | $206.5K | 0.10% | +16,963+27.2% | Added |
| Geode Capital Management, LLC | 74,097 | $192.7K | 0.00% | +3,091+4.4% | Added |
| Two Sigma Advisers, LP | 42,500 | $110.5K | 0.00% | +2,700+6.8% | Added |
| Dimensional Fund Advisors LP | 35,363 | $91.9K | 0.00% | +4,399+14.2% | Added |
| FNY Investment Advisers, LLC | 31,600 | $82.0K | 0.02% | +31,470+24,207.7% | Added |
| DRW Securities, LLC | 29,368 | $76.4K | 0.01% | +29,368 | New |
| XTX Topco Ltd | 25,860 | $67.2K | 0.00% | +25,860 | New |
| Bellevue Asset Management, LLC | 25,013 | $65.0K | 0.03% | +25,013 | New |
| BlackRock, Inc. | 22,793 | $59.3K | 0.00% | 00.0% | Unchanged |
| Perritt Capital Management Inc | 20,000 | $52.0K | 0.09% | +20,000 | New |
| Sentinus, LLC | 20,000 | $52.0K | 0.00% | +20,000 | New |
| Northern Trust Corp | 19,169 | $49.8K | 0.00% | +19,169 | New |
| Citadel Advisors LLC | 15,551 | $40.4K | 0.00% | +15,551 | New |
| Acadian Asset Management LLC | 10,237 | $26.0K | 0.00% | 00.0% | Unchanged |
| Daytona Street Capital LLC | 10,000 | $26.0K | 0.02% | +10,000 | New |
| MAI Capital Management | 3,575 | $9.29K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 3,049 | $7.93K | 0.00% | −86−2.7% | Reduced |
| Tower Research Capital LLC (TRC) | 1,713 | $4.45K | 0.00% | −2,610−60.4% | Reduced |
| Advisor Group Holdings, Inc. | 460 | $1.20K | 0.00% | +5+1.1% | Added |
| Wells Fargo & Company | 127 | $330 | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 125 | $325 | 0.00% | −161−56.3% | Reduced |
| Bank of America Corp | 85 | $221 | 0.00% | +11+14.9% | Added |
| CIBC Private Wealth Group, LLC | 83 | $216 | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 37 | $96 | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 23 | $60 | 0.00% | 00.0% | Unchanged |
| GWM Advisors LLC | 21 | $55 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 11 | $29 | 0.00% | −51−82.3% | Reduced |
| Vision Financial Markets LLC | 2 | $6 | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 1 | $3 | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 1 | $3 | 0.00% | 00.0% | Unchanged |
| TSFG, LLC | 1 | $0 | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 25 | $0 | 0.00% | +25 | New |
| Jaffetilchin Investment Partners, LLC | 0 | $0 | 0.00% | −17,437−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −5−100.0% | Sold out |
| Barclays PLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |