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aTYR PHARMA INC

ATYR
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001339970

No open-market purchases or sales by aTYR PHARMA INC insiders were filed in the last 90 days; 89 institutions reported holding it in 13F filings for Q2 2026, worth $23.2M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in aTYR PHARMA INC as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
84
−18 vs. Q3 2025
Shares held
54.8M
−7.06M (−11.4%) vs. Q3 2025
Total value
$42.1M
−$1.77M (−4.0%) vs. Q3 2025
New holders
16
23 more added
Sold out
34
25 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ATYR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 84 institutions
Q1 2021: 25 institutionsQ2 2021: 29 institutionsQ3 2021: 42 institutionsQ4 2021: 47 institutionsQ1 2022: 41 institutionsQ2 2022: 36 institutionsQ3 2022: 33 institutionsQ4 2022: 36 institutionsQ1 2023: 37 institutionsQ2 2023: 41 institutionsQ3 2023: 41 institutionsQ4 2023: 46 institutionsQ1 2024: 56 institutionsQ2 2024: 47 institutionsQ3 2024: 56 institutionsQ4 2024: 77 institutionsQ1 2025: 87 institutionsQ2 2025: 110 institutionsQ3 2025: 103 institutionsQ4 2025: 84 institutionsQ1 2026: 111 institutionsQ2 2026: 89 institutions
Value heldQ4 2025: $42.1M
Q1 2021: $26.3MQ2 2021: $33.8MQ3 2021: $172.1MQ4 2021: $153.5MQ1 2022: $105.0MQ2 2022: $53.1MQ3 2022: $57.2MQ4 2022: $40.2MQ1 2023: $72.8MQ2 2023: $77.0MQ3 2023: $58.7MQ4 2023: $58.1MQ1 2024: $81.5MQ2 2024: $75.1MQ3 2024: $84.3MQ4 2024: $198.6MQ1 2025: $186.5MQ2 2025: $336.5MQ3 2025: $43.9MQ4 2025: $42.1MQ1 2026: $43.7MQ2 2026: $23.2M
Institutions holding ATYR and their total value by quarter
QuarterHoldersValue
Q2 202689$23.2M
Q1 2026111$43.7M
Q4 202584$42.1M
Q3 2025103$43.9M
Q2 2025110$336.5M
Q1 202587$186.5M
Q4 202477$198.6M
Q3 202456$84.3M
Q2 202447$75.1M
Q1 202456$81.5M
Q4 202346$58.1M
Q3 202341$58.7M
Q2 202341$77.0M
Q1 202337$72.8M
Q4 202236$40.2M
Q3 202233$57.2M
Q2 202236$53.1M
Q1 202241$105.0M
Q4 202147$153.5M
Q3 202142$172.1M
Q2 202129$33.8M
Q1 202125$26.3M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding aTYR PHARMA INC; share changes are against Q3 2025.

Institutions holding ATYR in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC14,697,995$11.5M0.00%00.0%Unchanged
Federated Hermes, Inc.10,509,678$8.23M0.01%−34,759−0.3%Reduced
BlackRock, Inc.6,549,699$5.13M0.00%+75,815+1.2%Added
Vanguard Group Inc4,961,871$3.89M0.00%−669,064−11.9%Reduced
Gsa Capital Partners LLP2,630,638$2.06M0.18%+1,923,907+272.2%Added
Geode Capital Management, LLC2,283,717$1.79M0.00%+105,514+4.8%Added
State Street Corp1,724,843$1.35M0.00%−2,471,323−58.9%Reduced
UBS Group AG1,625,297$1.27M0.00%−2,880,658−63.9%Reduced
Morgan Stanley1,403,009$1.10M0.00%+692,668+97.5%Added
Two Sigma Advisers, LP841,350$658.9K0.00%+841,350New
AQR Capital Management LLC769,820$602.8K0.00%+769,820New
Susquehanna International Group, LLP764,743$598.9K0.00%+638,071+503.7%Added
Northern Trust Corp702,186$549.9K0.00%+28,064+4.2%Added
Tikvah Management LLC460,833$360.9K0.10%00.0%Unchanged
Two Sigma Investments, LP454,443$355.9K0.00%+243,443+115.4%Added
Goldman Sachs Group Inc345,587$270.6K0.00%−342,578−49.8%Reduced
Nuveen, LLC227,941$178.5K0.00%00.0%Unchanged
Charles Schwab Investment Management Inc221,767$173.7K0.00%−39,276−15.0%Reduced
Bank of New York Mellon Corp193,532$151.6K0.00%−6,266−3.1%Reduced
Group One Trading, L.P.191,048$149.6K0.00%+173,808+1,008.2%Added
Jane Street Group, LLC188,149$147.3K0.00%−39,636−17.4%Reduced
Victory Capital Management Inc181,966$142.5K0.00%−10,847−5.6%Reduced
Barclays PLC174,182$136.4K0.00%−167,177−49.0%Reduced
Bank of America Corp126,700$99.2K0.00%−50,971−28.7%Reduced
Deutsche Bank AG120,341$93.9K0.00%+117,239+3,779.5%Added
Wells Fargo & Company116,717$91.4K0.00%+5,658+5.1%Added
JPMorgan Chase & Co110,373$86.4K0.00%+4,556+4.3%Added
Rhumbline Advisers99,762$78.1K0.00%−22,645−18.5%Reduced
Dimensional Fund Advisors LP97,497$76.2K0.00%−117,049−54.6%Reduced
XTX Topco Ltd79,365$62.2K0.00%−233,045−74.6%Reduced
Virtu Financial LLC78,953$62.0K0.00%+78,953New
Alliancebernstein L.P.64,480$50.5K0.00%00.0%Unchanged
Kingswood Wealth Advisors, LLC52,000$40.7K0.00%+52,000New
ADAR1 Capital Management, LLC50,685$39.7K0.00%−124,315−71.0%Reduced
Invesco Ltd.46,233$36.2K0.00%+374+0.8%Added
Price T Rowe Associates Inc46,126$36.0K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.41,844$32.8K0.00%−7,678−15.5%Reduced
Two Sigma Securities, LLC39,006$30.5K0.00%+39,006New
SEI Investments Co33,829$26.5K0.00%00.0%Unchanged
Intech Investment Management LLC31,774$24.9K0.00%00.0%Unchanged
LPL Financial LLC30,100$23.6K0.00%+30,100New
Rockefeller Capital Management L.P.28,118$22.0K0.00%00.0%Unchanged
New York State Common Retirement Fund27,500$21.5K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA26,518$20.8K0.00%+5,823+28.1%Added
Simplex Trading, LLC26,227$20.5K0.00%+26,227New
Police & Firemen's Retirement System of New Jersey26,081$20.4K0.00%00.0%Unchanged
SG Americas Securities, LLC24,032$19.0K0.00%+2,569+12.0%Added
Neuberger Berman Group LLC20,454$16.0K0.00%+20,454New
RBF Capital, LLC20,000$15.7K0.00%00.0%Unchanged
ProShare Advisors LLC17,524$13.7K0.00%+2,651+17.8%Added
Voya Investment Management LLC16,594$13.0K0.00%00.0%Unchanged
Raymond James Financial Inc15,961$12.5K0.00%+800+5.3%Added
HSBC Holdings PLC16,136$12.1K0.00%−30.0%Reduced
MAI Capital Management15,239$11.9K0.00%−7,602−33.3%Reduced
Tower Research Capital LLC (TRC)13,729$10.8K0.00%−20,105−59.4%Reduced
Apollon Wealth Management, LLC12,900$10.1K0.00%−7,000−35.2%Reduced
Crossmark Global Holdings, Inc.12,666$9.92K0.00%+12,666New
Gladstone Institutional Advisory LLC11,300$8.85K0.00%−2,000−15.0%Reduced
R Squared Ltd11,255$8.81K0.00%+11,255New
Belpointe Asset Management LLC10,438$8.17K0.00%00.0%Unchanged
Legal & General Group Plc9,570$7.49K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.8,881$6.96K0.00%00.0%Unchanged
CWM, LLC7,978$6.00K0.00%+7,959+41,889.5%Added
Russell Investments Group, Ltd.7,205$5.64K0.00%−259−3.5%Reduced
Royal Bank of Canada5,253$5.00K0.00%−9,652−64.8%Reduced
California State Teachers Retirement System5,901$4.62K0.00%+469+8.6%Added
FNY Investment Advisers, LLC4,800$3.00K0.00%+4,100+585.7%Added
Newbridge Financial Services Group, Inc.3,600$2.82K0.00%+3,100+620.0%Added
Citigroup Inc3,070$2.40K0.00%−2,647−46.3%Reduced
Amalgamated Bank3,014$2.00K0.00%+43+1.4%Added
Farther Finance Advisors, LLC2,225$1.74K0.00%+125+6.0%Added
Jones Financial Companies LLLP1,500$1.18K0.00%+1,500New
Vision Retirement, LLC1,500$1.18K0.00%+1,500New
Sterling Capital Management LLC934$7310.00%+331+54.9%Added
The PNC Financial Services Group, Inc.478$3740.00%−333−41.1%Reduced
MCF Advisors LLC400$3140.00%00.0%Unchanged
Natixis280$2190.00%+280New
Essential Partners LLC175$1370.00%+175New
EverSource Wealth Advisors, LLC161$1260.00%+161New
Larson Financial Group LLC150$1170.00%00.0%Unchanged
Rothschild Investment LLC109$850.00%+109New
Caitong International Asset Management Co., Ltd67$520.00%00.0%Unchanged
Caldwell Sutter Capital, Inc.52$410.00%00.0%Unchanged
Rosalind Advisors, Inc.1,039,080––00.0%Unchanged
Millennium Management LLC0$00.00%−1,890,921−100.0%Sold out
Tang Capital Management LLC0$00.00%−671,134−100.0%Sold out
State of Wisconsin Investment Board0$00.00%−438,262−100.0%Sold out
Ensign Peak Advisors, Inc0$00.00%−414,732−100.0%Sold out
Artia Global Partners LP0$00.00%−372,276−100.0%Sold out
Wellington Management Group LLP0$00.00%−289,231−100.0%Sold out
Flputnam Investment Management Co0$00.00%−235,255−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−234,613−100.0%Sold out
Rafferty Asset Management, LLC0$00.00%−170,610−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−147,851−100.0%Sold out
Main Street Financial Solutions, LLC0$00.00%−144,950−100.0%Sold out
Squarepoint Ops LLC0$00.00%−124,924−100.0%Sold out
Toronto Dominion Bank0$00.00%−109,400−100.0%Sold out
Woodline Partners LP0$00.00%−102,687−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−83,312−100.0%Sold out
Los Angeles Capital Management LLC0$00.00%−45,830−100.0%Sold out