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Arrowhead Pharmaceuticals, Inc.

ARWR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000879407

In the last 90 days, Arrowhead Pharmaceuticals, Inc. insiders filed 0 open-market purchases and 2 sales; 501 institutions reported holding it in 13F filings for Q2 2026, worth $9.73B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Arrowhead Pharmaceuticals, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
401
+100 vs. Q3 2025
Shares held
116.0M
+5.08M (+4.6%) vs. Q3 2025
Total value
$7.70B
+$3.88B (+101.3%) vs. Q3 2025
New holders
127
125 more added
Sold out
27
110 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ARWR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 401 institutions
Q1 2021: 289 institutionsQ2 2021: 314 institutionsQ3 2021: 297 institutionsQ4 2021: 311 institutionsQ1 2022: 307 institutionsQ2 2022: 279 institutionsQ3 2022: 278 institutionsQ4 2022: 282 institutionsQ1 2023: 257 institutionsQ2 2023: 274 institutionsQ3 2023: 257 institutionsQ4 2023: 266 institutionsQ1 2024: 273 institutionsQ2 2024: 272 institutionsQ3 2024: 272 institutionsQ4 2024: 269 institutionsQ1 2025: 264 institutionsQ2 2025: 281 institutionsQ3 2025: 303 institutionsQ4 2025: 401 institutionsQ1 2026: 437 institutionsQ2 2026: 501 institutions
Value heldQ4 2025: $7.70B
Q1 2021: $4.55BQ2 2021: $5.54BQ3 2021: $4.16BQ4 2021: $4.51BQ1 2022: $3.19BQ2 2022: $2.54BQ3 2022: $2.35BQ4 2022: $2.97BQ1 2023: $1.85BQ2 2023: $2.57BQ3 2023: $2.01BQ4 2023: $2.37BQ1 2024: $2.76BQ2 2024: $2.54BQ3 2024: $1.90BQ4 2024: $1.88BQ1 2025: $1.34BQ2 2025: $1.67BQ3 2025: $3.83BQ4 2025: $7.70BQ1 2026: $7.58BQ2 2026: $9.73B
Institutions holding ARWR and their total value by quarter
QuarterHoldersValue
Q2 2026501$9.73B
Q1 2026437$7.58B
Q4 2025401$7.70B
Q3 2025303$3.83B
Q2 2025281$1.67B
Q1 2025264$1.34B
Q4 2024269$1.88B
Q3 2024272$1.90B
Q2 2024272$2.54B
Q1 2024273$2.76B
Q4 2023266$2.37B
Q3 2023257$2.01B
Q2 2023274$2.57B
Q1 2023257$1.85B
Q4 2022282$2.97B
Q3 2022278$2.35B
Q2 2022279$2.54B
Q1 2022307$3.19B
Q4 2021311$4.51B
Q3 2021297$4.16B
Q2 2021314$5.54B
Q1 2021289$4.55B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Arrowhead Pharmaceuticals, Inc.; share changes are against Q3 2025.

Institutions holding ARWR in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock, Inc.21,318,582$1.42B0.02%+1,093,757+5.4%Added
Vanguard Group Inc15,293,121$1.02B0.01%−742,749−4.6%Reduced
Avoro Capital Advisors LLC10,625,000$705.4M6.93%−275,000−2.5%Reduced
FMR LLC6,520,408$432.9M0.02%+760,578+13.2%Added
State Street Corp6,403,830$425.2M0.01%+6,466+0.1%Added
Geode Capital Management, LLC3,264,963$216.8M0.01%+133,921+4.3%Added
Slate Path Capital LP2,523,500$167.5M2.26%−2,458,500−49.3%Reduced
Baker Bros. Advisors LP2,175,645$144.4M0.85%+504,883+30.2%Added
Arrowstreet Capital, Limited Partnership2,087,953$138.6M0.08%+6,264+0.3%Added
Fred Alger Management, LLC1,832,997$121.7M0.48%+1,526,164+497.4%Added
Deerfield Management Company, L.P. (Series C)1,832,946$121.7M1.56%+839,946+84.6%Added
Driehaus Capital Management LLC1,769,340$117.5M0.80%−330,058−15.7%Reduced
Norges Bank1,704,464$113.2M0.01%+1,704,464New
Goldman Sachs Group Inc1,677,522$111.4M0.02%−96,356−5.4%Reduced
Siren, L.L.C.1,500,476$99.6M2.97%−1,169,404−43.8%Reduced
Morgan Stanley1,476,005$98.0M0.01%−226,669−13.3%Reduced
Charles Schwab Investment Management Inc1,353,719$89.9M0.01%+7,859+0.6%Added
Northern Trust Corp1,346,257$89.4M0.01%+34,667+2.6%Added
Fisher Asset Management, LLC1,311,727$87.1M0.03%+257,933+24.5%Added
Janus Henderson Group PLC1,280,446$85.0M0.04%+306,879+31.5%Added
UBS Asset Management Americas Inc1,260,380$83.7M0.02%−499,109−28.4%Reduced
Pictet Asset Management Holding SA1,028,736$68.6M0.07%+737,713+253.5%Added
UBS Group AG987,287$65.5M0.01%+69,104+7.5%Added
Vestal Point Capital, LP900,000$59.8M2.19%+900,000New
Bank of New York Mellon Corp887,848$58.9M0.01%+73,300+9.0%Added
Price T Rowe Associates Inc838,818$55.7M0.01%+728,573+660.9%Added
Western Financial Corp820,239$54.5M21.60%00.0%Unchanged
Principal Financial Group Inc715,539$47.5M0.02%−64,593−8.3%Reduced
Assenagon Asset Management S.A.684,889$45.5M0.07%+304,264+79.9%Added
Connor, Clark & Lunn Investment Management Ltd.663,262$44.0M0.12%+538,733+432.6%Added
Bank of America Corp622,029$41.3M0.00%−138,658−18.2%Reduced
JPMorgan Chase & Co611,910$40.6M0.00%−163,807−21.1%Reduced
RTW Investments, LP584,716$38.8M0.39%+584,716New
Adage Capital Partners GP, L.L.C.550,000$36.5M0.06%+550,000New
Invesco Ltd.547,758$36.4M0.00%+44,866+8.9%Added
Public Sector Pension Investment Board478,514$31.8M0.11%−60,822−11.3%Reduced
Citadel Advisors LLC474,259$31.5M0.02%+156,645+49.3%Added
Summit Partners Public Asset Management, LLC470,000$31.2M0.88%+470,000New
Voya Investment Management LLC422,731$28.1M0.03%+285,215+207.4%Added
Woodline Partners LP400,184$26.6M0.10%−599,974−60.0%Reduced
Privium Fund Management B.V.398,204$26.4M4.87%−75,747−16.0%Reduced
Legal & General Group Plc395,311$26.2M0.01%+8,937+2.3%Added
Balyasny Asset Management LLC376,216$25.0M0.05%−416,750−52.6%Reduced
Alyeska Investment Group, L.P.375,371$24.9M0.07%+375,371New
Eventide Asset Management, LLC370,000$24.6M0.38%+370,000New
Rhumbline Advisers352,395$23.4M0.02%−18,717−5.0%Reduced
Nordea Investment Management AB324,251$21.6M0.02%−48,031−12.9%Reduced
Barclays PLC321,833$21.4M0.01%−28,406−8.1%Reduced
Nuveen, LLC288,578$19.2M0.01%+10,242+3.7%Added
Voloridge Investment Management, LLC288,511$19.2M0.07%−114,148−28.3%Reduced
Standard Life Aberdeen plc286,146$19.0M0.03%−234,498−45.0%Reduced
FengHe Fund Management Pte. Ltd.266,700$17.7M1.00%+266,700New
Ameriprise Financial Inc257,477$17.1M0.00%−16,686−6.1%Reduced
Trexquant Investment LP250,944$16.7M0.15%+250,944New
Swiss National Bank245,400$16.3M0.01%+31,300+14.6%Added
Deutsche Bank AG242,074$16.1M0.01%−3,998−1.6%Reduced
First Trust Advisors LP237,730$15.8M0.01%+29,775+14.3%Added
Clearbridge Investments, LLC208,062$13.8M0.01%−183,093−46.8%Reduced
Raymond James Financial Inc198,387$13.2M0.00%−28,882−12.7%Reduced
Hillsdale Investment Management Inc.193,850$12.9M0.36%+193,850New
Pinnacle Associates Ltd191,669$12.7M0.16%−11,645−5.7%Reduced
Alliancebernstein L.P.172,666$11.5M0.00%+16,772+10.8%Added
Universal- Beteiligungs- und Servicegesellschaft mbH159,538$10.6M0.02%−1,447−0.9%Reduced
Skandinaviska Enskilda Banken AB (publ)159,532$10.6M0.04%+159,532New
Silvercrest Asset Management Group LLC158,622$10.5M0.07%−114,352−41.9%Reduced
Wells Fargo & Company152,507$10.1M0.00%+72,272+90.1%Added
Prudential Financial Inc152,225$10.1M0.01%+15,580+11.4%Added
New York State Teachers Retirement System149,776$9.94M0.02%+1,300+0.9%Added
Dimensional Fund Advisors LP147,412$9.79M0.00%−327,050−68.9%Reduced
AQR Capital Management LLC147,353$9.78M0.01%+4,528+3.2%Added
D. E. Shaw & Co., Inc.146,064$9.70M0.01%+125,763+619.5%Added
Rhenman & Partners Asset Management AB144,500$9.59M0.90%+144,500New
Wealth Effects LLC143,300$9.51M2.98%−25,150−14.9%Reduced
WCM Investment Management, LLC138,905$9.34M0.02%+138,905New
Mirae Asset Global ETFs Holdings Ltd.133,875$8.89M0.01%−4,145−3.0%Reduced
HighTower Advisors, LLC133,229$8.85M0.01%+340+0.3%Added
Marshall Wace, LLP123,855$8.22M0.01%−1,312,985−91.4%Reduced
Russell Investments Group, Ltd.122,115$8.11M0.01%+109,231+847.8%Added
Great West Life Assurance Co118,750$7.88M0.01%−11,208−8.6%Reduced
California State Teachers Retirement System118,372$7.86M0.01%+14,390+13.8%Added
SEI Investments Co112,279$7.45M0.01%+98,663+724.6%Added
Weiss Asset Management LP111,375$7.39M0.10%+111,375New
Franklin Resources Inc107,366$7.13M0.00%−9,138−7.8%Reduced
Neuberger Berman Group LLC100,385$6.66M0.00%+87,000+650.0%Added
LPL Financial LLC100,277$6.66M0.00%+50,113+99.9%Added
Integral Health Asset Management, LLC100,000$6.64M0.34%−125,000−55.6%Reduced
Manufacturers Life Insurance Company, The98,151$6.55M0.01%+35,151+55.8%Added
Polygon Management Ltd.96,935$6.44M1.36%+15,094+18.4%Added
Thrivent Financial for Lutherans95,001$6.31M0.01%−4,743−4.8%Reduced
Victory Capital Management Inc92,623$6.15M0.00%+47,454+105.1%Added
Platinum Investment Management Ltd89,484$5.94M1.37%−21,538−19.4%Reduced
Rafferty Asset Management, LLC84,469$5.61M0.02%−29,910−26.1%Reduced
Aquatic Capital Management LLC80,958$5.37M0.15%+55,287+215.4%Added
State of Wisconsin Investment Board79,214$5.26M0.01%+14,339+22.1%Added
Erste Asset Management GmbH73,000$5.08M0.04%00.0%Unchanged
KC Investment Advisors, LLC75,000$4.98M1.21%00.0%Unchanged
ACT Capital Management, LLC75,000$4.98M4.03%+75,000New
Creative Planning74,421$4.94M0.00%+22,415+43.1%Added
MetLife Investment Management73,040$4.85M0.02%+1,077+1.5%Added
State of Alaska, Department of Revenue70,399$4.67M0.05%+831+1.2%Added