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Apogee Therapeutics, Inc.

APGEDelisted Sep 3, 2026
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001974640

Apogee Therapeutics, Inc. was delisted on Sep 3, 2026; its insiders filed their last Form 4 on Sep 3, 2026; 288 institutions reported holding it in 13F filings for Q2 2026, worth $8.93B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q1 2026

Institutional positions in Apogee Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
224
+19 vs. Q4 2025
Shares held
79.1M
+12.2M (+18.2%) vs. Q4 2025
Total value
$6.64B
+$1.59B (+31.5%) vs. Q4 2025
New holders
49
104 more added
Sold out
30
53 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APGE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 224 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 73 institutionsQ4 2023: 85 institutionsQ1 2024: 139 institutionsQ2 2024: 139 institutionsQ3 2024: 139 institutionsQ4 2024: 158 institutionsQ1 2025: 169 institutionsQ2 2025: 183 institutionsQ3 2025: 174 institutionsQ4 2025: 207 institutionsQ1 2026: 224 institutionsQ2 2026: 288 institutions
Value heldQ1 2026: $6.64B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $848.7MQ4 2023: $1.16BQ1 2024: $3.52BQ2 2024: $2.13BQ3 2024: $3.29BQ4 2024: $2.62BQ1 2025: $2.30BQ2 2025: $2.51BQ3 2025: $2.37BQ4 2025: $5.27BQ1 2026: $6.64BQ2 2026: $8.93B
Institutions holding APGE and their total value by quarter
QuarterHoldersValue
Q2 2026288$8.93B
Q1 2026224$6.64B
Q4 2025207$5.27B
Q3 2025174$2.37B
Q2 2025183$2.51B
Q1 2025169$2.30B
Q4 2024158$2.62B
Q3 2024139$3.29B
Q2 2024139$2.13B
Q1 2024139$3.52B
Q4 202385$1.16B
Q3 202373$848.7M
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Apogee Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding APGE in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
T. Rowe Price Investment Management, Inc.10,300,984$867.0M0.60%+7,568,528+277.0%Added
FMR LLC9,262,291$779.6M0.04%+1,037,253+12.6%Added
VR Adviser, LLC8,493,321$714.9M26.68%00.0%Unchanged
Wellington Management Group LLP4,375,703$368.3M0.07%−370,882−7.8%Reduced
BlackRock, Inc.4,085,651$343.9M0.01%+301,657+8.0%Added
RTW Investments, LP2,782,097$234.2M2.33%+70,000+2.6%Added
Vanguard Capital Management LLC2,502,095$210.6M0.01%+2,502,095New
Janus Henderson Group PLC2,360,596$198.8M0.09%+297,992+14.4%Added
State Street Corp2,162,964$182.1M0.01%+472,778+28.0%Added
Driehaus Capital Management LLC1,920,800$161.7M1.19%−262,904−12.0%Reduced
Perceptive Advisors LLC1,540,384$129.7M2.56%−790,267−33.9%Reduced
Paradigm Biocapital Advisors LP1,348,243$113.5M2.32%+225,000+20.0%Added
Affinity Asset Advisors, LLC1,284,926$108.2M6.34%+50,000+4.0%Added
Geode Capital Management, LLC1,217,289$102.5M0.01%+158,204+14.9%Added
UBS Group AG1,144,328$96.3M0.02%+169,502+17.4%Added
Price T Rowe Associates Inc1,143,152$96.2M0.01%−93,983−7.6%Reduced
Vestal Point Capital, LP1,100,000$92.6M2.59%+550,000+100.0%Added
Frontier Capital Management Co LLC1,064,483$89.6M0.92%+584,030+121.6%Added
JPMorgan Chase & Co1,110,470$87.4M0.01%−262,596−19.1%Reduced
Bank of America Corp900,871$75.8M0.01%+107,176+13.5%Added
Alliancebernstein L.P.990,297$74.7M0.02%−103,360−9.5%Reduced
Mercer Global Advisors Inc831,428$70.0M0.10%−59,237−6.7%Reduced
Goldman Sachs Group Inc652,590$54.9M0.01%+87,180+15.4%Added
Citadel Advisors LLC598,902$50.4M0.04%−168,079−21.9%Reduced
Morgan Stanley595,032$50.1M0.00%−295,232−33.2%Reduced
Jennison Associates LLC585,016$49.2M0.03%+6,389+1.1%Added
Remedium Capital Partners, LLC583,591$49.1M17.47%00.0%Unchanged
First Light Asset Management, LLC576,684$48.5M4.35%+291,693+102.4%Added
Eventide Asset Management, LLC557,423$46.9M0.78%+121,408+27.8%Added
Polar Capital Holdings Plc539,177$45.4M0.20%+35,638+7.1%Added
First Turn Management, LLC513,770$43.2M4.83%+38,931+8.2%Added
Braidwell LP478,667$40.3M1.34%−96,400−16.8%Reduced
Novo Holdings A/S450,000$37.9M3.07%−120,000−21.1%Reduced
Federated Hermes, Inc.442,738$37.3M0.06%+314,807+246.1%Added
Balyasny Asset Management LLC438,654$36.9M0.07%+438,654New
Charles Schwab Investment Management Inc420,684$35.4M0.01%+39,322+10.3%Added
Franklin Resources Inc405,538$34.1M0.01%−45,464−10.1%Reduced
Vanguard Portfolio Management LLC396,330$33.4M0.00%+396,330New
Northern Trust Corp390,879$32.9M0.00%+63,503+19.4%Added
Opaleye Management Inc.390,000$32.8M4.32%+1,743+0.4%Added
Great Point Partners LLC374,000$31.5M7.71%00.0%Unchanged
Vanguard Fiduciary Trust Co368,961$31.1M0.01%+368,961New
Loomis Sayles & Co L P362,781$30.5M0.04%+107,342+42.0%Added
Capital World Investors348,674$29.3M0.00%+221,056+173.2%Added
Fairmount Funds Management LLC298,647$25.1M1.82%−1,750,000−85.4%Reduced
Deep Track Capital, LP285,000$24.0M0.49%+285,000New
Two Sigma Investments, LP281,386$23.7M0.02%+176,145+167.4%Added
Woodline Partners LP261,120$22.0M0.08%+50,654+24.1%Added
Pictet Asset Management Holding SA261,050$22.0M0.02%−51,833−16.6%Reduced
Adage Capital Partners GP, L.L.C.250,000$21.0M0.03%+10,000+4.2%Added
Candriam Luxembourg S.C.A.223,541$18.8M0.10%+32,223+16.8%Added
BNP Paribas Arbitrage, SA220,099$18.5M0.01%+210,134+2,108.7%Added
TD Asset Management Inc184,792$15.6M0.01%+55,502+42.9%Added
Standard Life Aberdeen plc143,379$12.1M0.02%+107,276+297.1%Added
Nicholas Investment Partners, LP130,992$11.0M0.80%+18,068+16.0%Added
Nuveen, LLC128,115$10.8M0.00%+7,065+5.8%Added
Universal- Beteiligungs- und Servicegesellschaft mbH128,015$10.8M0.02%+386+0.3%Added
Bank of New York Mellon Corp126,757$10.7M0.00%+8,673+7.3%Added
Kennedy Capital Management, Inc.122,669$10.3M0.22%−2,310−1.8%Reduced
ArrowMark Colorado Holdings LLC109,410$9.21M0.24%00.0%Unchanged
Seven Grand Managers, LLC100,000$8.42M0.56%+50,000+100.0%Added
Victory Capital Management Inc95,137$8.01M0.01%−13,130−12.1%Reduced
Millennium Management LLC92,592$7.79M0.01%−48,135−34.2%Reduced
Deutsche Bank AG91,421$7.69M0.00%+12,060+15.2%Added
Schroder Investment Management Group96,656$7.61M0.01%−8,344−7.9%Reduced
Nomura Holdings Inc88,561$7.45M0.06%+11,663+15.2%Added
Ensign Peak Advisors, Inc82,300$6.93M0.01%+80,050+3,557.8%Added
Marshall Wace, LLP80,201$6.75M0.01%+29,457+58.1%Added
Simplex Trading, LLC77,808$6.55M0.20%+15,009+23.9%Added
Parkman Healthcare Partners LLC77,686$6.54M0.68%−52,383−40.3%Reduced
Swiss National Bank75,600$6.36M0.00%+12,700+20.2%Added
Granahan Investment Management Inc75,086$6.32M0.31%−19,634−20.7%Reduced
Alyeska Investment Group, L.P.75,000$6.31M0.02%+75,000New
Rhenman & Partners Asset Management AB75,000$6.31M0.78%+75,000New
WCM Investment Management, LLC76,030$5.99M0.01%+76,030New
Boxer Capital Management, LLC70,000$5.89M0.77%00.0%Unchanged
Ameriprise Financial Inc69,888$5.88M0.00%−53,012−43.1%Reduced
Manufacturers Life Insurance Company, The68,696$5.78M0.00%−12,136−15.0%Reduced
Prudential Financial Inc63,900$5.38M0.01%+9,600+17.7%Added
Fifth Third Bancorp63,800$5.37M0.01%+63,800New
Rafferty Asset Management, LLC60,397$5.08M0.02%+11,778+24.2%Added
D. E. Shaw & Co., Inc.58,835$4.95M0.00%−4,415−7.0%Reduced
Russell Investments Group, Ltd.58,484$4.92M0.01%+8,485+17.0%Added
Platinum Investment Management Ltd58,314$4.91M1.24%−10,898−15.7%Reduced
Holocene Advisors, LP57,473$4.84M0.01%+57,473New
UBS Asset Management Americas Inc56,352$4.74M0.00%+6,547+13.1%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.54,437$4.58M0.01%+14,591+36.6%Added
Lisanti Capital Growth, LLC52,260$4.40M1.11%+52,260New
Barclays PLC50,396$4.24M0.00%−82,797−62.2%Reduced
Rhumbline Advisers48,678$4.10M0.00%+2,707+5.9%Added
Alps Advisors Inc45,586$3.84M0.02%+664+1.5%Added
XTX Topco Ltd42,899$3.61M0.06%+23,873+125.5%Added
SEI Investments Co42,203$3.55M0.00%+25,874+158.5%Added
Man Group plc41,815$3.52M0.01%+30,652+274.6%Added
First Trust Advisors LP40,776$3.43M0.00%+37,358+1,093.0%Added
Invesco Ltd.38,763$3.26M0.00%−31,924−45.2%Reduced
Squarepoint Ops LLC38,348$3.23M0.01%+38,348New
California State Teachers Retirement System38,161$3.21M0.00%+7,403+24.1%Added
KBC Group NV37,843$3.19M0.01%+37,843New
HighVista Strategies LLC35,761$3.01M0.83%−53,468−59.9%Reduced