Apogee Therapeutics, Inc.
APGEDelisted Sep 3, 2026- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001974640
Apogee Therapeutics, Inc. was delisted on Sep 3, 2026; its insiders filed their last Form 4 on Sep 3, 2026; 288 institutions reported holding it in 13F filings for Q2 2026, worth $8.93B in total; Soros Fund Management was the only superinvestor holding it.
13F holders, Q4 2025
Institutional positions in Apogee Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 207
- +35 vs. Q3 2025
- Shares held
- 69.8M
- +10.2M (+17.2%) vs. Q3 2025
- Total value
- $5.27B
- +$2.90B (+122.6%) vs. Q3 2025
- New holders
- 53
- 86 more added
- Sold out
- 18
- 46 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting APGE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 288 | $8.93B |
| Q1 2026 | 224 | $6.64B |
| Q4 2025 | 207 | $5.27B |
| Q3 2025 | 174 | $2.37B |
| Q2 2025 | 183 | $2.51B |
| Q1 2025 | 169 | $2.30B |
| Q4 2024 | 158 | $2.62B |
| Q3 2024 | 139 | $3.29B |
| Q2 2024 | 139 | $2.13B |
| Q1 2024 | 139 | $3.52B |
| Q4 2023 | 85 | $1.16B |
| Q3 2023 | 73 | $848.7M |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Apogee Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| VR Adviser, LLC | 8,493,321 | $641.1M | 31.67% | 00.0% | Unchanged |
| FMR LLC | 8,225,038 | $620.8M | 0.03% | +1,308,576+18.9% | Added |
| Wellington Management Group LLP | 4,746,585 | $358.3M | 0.06% | +22,884+0.5% | Added |
| BlackRock, Inc. | 3,783,994 | $285.6M | 0.00% | +1,097,968+40.9% | Added |
| Vanguard Group Inc | 2,857,824 | $215.7M | 0.00% | +612,193+27.3% | Added |
| T. Rowe Price Investment Management, Inc. | 2,732,456 | $206.2M | 0.13% | +2,731,015+189,522.2% | Added |
| RTW Investments, LP | 2,712,097 | $204.7M | 2.05% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 2,330,651 | $175.9M | 3.22% | +978,662+72.4% | Added |
| Driehaus Capital Management LLC | 2,183,704 | $164.8M | 1.12% | +25,202+1.2% | Added |
| Janus Henderson Group PLC | 2,062,604 | $155.7M | 0.07% | +1,576,626+324.4% | Added |
| Fairmount Funds Management LLC | 2,048,647 | $154.6M | 11.77% | 00.0% | Unchanged |
| State Street Corp | 1,690,186 | $127.6M | 0.00% | +34,638+2.1% | Added |
| JPMorgan Chase & Co | 1,373,066 | $103.6M | 0.01% | +235,335+20.7% | Added |
| Price T Rowe Associates Inc | 1,237,135 | $93.4M | 0.01% | +486,606+64.8% | Added |
| Affinity Asset Advisors, LLC | 1,234,926 | $93.2M | 6.70% | +61,500+5.2% | Added |
| Paradigm Biocapital Advisors LP | 1,123,243 | $84.8M | 2.27% | −398,514−26.2% | Reduced |
| Alliancebernstein L.P. | 1,093,657 | $82.5M | 0.03% | −325,475−22.9% | Reduced |
| Geode Capital Management, LLC | 1,059,085 | $80.0M | 0.00% | +166,882+18.7% | Added |
| UBS Group AG | 974,826 | $73.6M | 0.01% | +175,361+21.9% | Added |
| Mercer Global Advisors Inc | 890,665 | $67.2M | 0.10% | −79,916−8.2% | Reduced |
| Morgan Stanley | 890,264 | $67.2M | 0.00% | +425,301+91.5% | Added |
| Bank of America Corp | 793,695 | $59.9M | 0.00% | +399,783+101.5% | Added |
| Citadel Advisors LLC | 766,981 | $57.9M | 0.04% | −402,263−34.4% | Reduced |
| Remedium Capital Partners, LLC | 583,591 | $44.0M | 25.88% | +583,591 | New |
| Jennison Associates LLC | 578,627 | $43.7M | 0.03% | +578,627 | New |
| Braidwell LP | 575,067 | $43.4M | 1.39% | −863,678−60.0% | Reduced |
| Novo Holdings A/S | 570,000 | $43.0M | 3.34% | +70,000+14.0% | Added |
| Goldman Sachs Group Inc | 565,410 | $42.7M | 0.01% | −34,206−5.7% | Reduced |
| Vestal Point Capital, LP | 550,000 | $41.5M | 1.52% | +125,000+29.4% | Added |
| Sofinnova Investments, Inc. | 534,845 | $40.4M | 1.74% | −30,572−5.4% | Reduced |
| Polar Capital Holdings Plc | 503,539 | $38.0M | 0.17% | −20,555−3.9% | Reduced |
| Avoro Capital Advisors LLC | 500,000 | $37.7M | 0.37% | +500,000 | New |
| Frontier Capital Management Co LLC | 480,453 | $36.3M | 0.38% | +106,046+28.3% | Added |
| First Turn Management, LLC | 474,839 | $35.8M | 4.10% | +72,028+17.9% | Added |
| Franklin Resources Inc | 451,002 | $34.0M | 0.01% | −279,759−38.3% | Reduced |
| Eventide Asset Management, LLC | 436,015 | $32.9M | 0.51% | +436,015 | New |
| Opaleye Management Inc. | 388,257 | $29.3M | 3.87% | +25,000+6.9% | Added |
| Charles Schwab Investment Management Inc | 381,362 | $28.8M | 0.00% | +61,459+19.2% | Added |
| Great Point Partners LLC | 374,000 | $28.2M | 9.15% | +70,000+23.0% | Added |
| Northern Trust Corp | 327,376 | $24.7M | 0.00% | +42,893+15.1% | Added |
| Pictet Asset Management Holding SA | 312,883 | $23.6M | 0.02% | +312,883 | New |
| First Light Asset Management, LLC | 284,991 | $21.5M | 1.64% | +284,991 | New |
| Loomis Sayles & Co L P | 255,439 | $19.3M | 0.02% | +255,439 | New |
| Adage Capital Partners GP, L.L.C. | 240,000 | $18.1M | 0.03% | +5,000+2.1% | Added |
| Woodline Partners LP | 210,466 | $15.9M | 0.06% | +153,145+267.2% | Added |
| Trails Edge Capital Partners, LP | 192,000 | $14.5M | 3.58% | +192,000 | New |
| Candriam Luxembourg S.C.A. | 191,318 | $14.4M | 0.07% | +65,237+51.7% | Added |
| Millennium Management LLC | 140,727 | $10.6M | 0.01% | −289,736−67.3% | Reduced |
| Barclays PLC | 133,193 | $10.1M | 0.00% | −509,123−79.3% | Reduced |
| Parkman Healthcare Partners LLC | 130,069 | $9.82M | 0.93% | +24,238+22.9% | Added |
| TD Asset Management Inc | 129,290 | $9.76M | 0.01% | +46,050+55.3% | Added |
| Federated Hermes, Inc. | 127,931 | $9.66M | 0.02% | +127,931 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 127,629 | $9.63M | 0.02% | −3,807−2.9% | Reduced |
| Capital World Investors | 127,618 | $9.63M | 0.00% | 00.0% | Unchanged |
| Kennedy Capital Management, Inc. | 124,979 | $9.43M | 0.20% | +928+0.7% | Added |
| Ameriprise Financial Inc | 122,900 | $9.28M | 0.00% | +19,748+19.1% | Added |
| Nuveen, LLC | 121,050 | $9.14M | 0.00% | +37,759+45.3% | Added |
| Bank of New York Mellon Corp | 118,084 | $8.91M | 0.00% | +10,544+9.8% | Added |
| Nicholas Investment Partners, LP | 112,924 | $8.52M | 0.62% | +112,924 | New |
| ArrowMark Colorado Holdings LLC | 109,410 | $8.26M | 0.18% | 00.0% | Unchanged |
| Victory Capital Management Inc | 108,267 | $8.17M | 0.00% | −108,946−50.2% | Reduced |
| Schroder Investment Management Group | 105,000 | $7.95M | 0.01% | −110,846−51.4% | Reduced |
| Two Sigma Investments, LP | 105,241 | $7.94M | 0.01% | −17,134−14.0% | Reduced |
| Neuberger Berman Group LLC | 99,648 | $7.52M | 0.01% | +99,648 | New |
| Granahan Investment Management Inc | 94,720 | $7.15M | 0.31% | −37,680−28.5% | Reduced |
| HighVista Strategies LLC | 89,229 | $6.74M | 1.73% | −17,878−16.7% | Reduced |
| Manufacturers Life Insurance Company, The | 80,832 | $6.12M | 0.01% | +17,607+27.8% | Added |
| StemPoint Capital LP | 80,574 | $6.08M | 1.04% | +80,574 | New |
| Deutsche Bank AG | 79,361 | $5.99M | 0.00% | +2,814+3.7% | Added |
| Nomura Holdings Inc | 76,898 | $5.80M | 0.02% | +76,898 | New |
| SG Americas Securities, LLC | 73,262 | $5.53M | 0.01% | −60,964−45.4% | Reduced |
| Invesco Ltd. | 70,687 | $5.34M | 0.00% | +41,549+142.6% | Added |
| Boxer Capital Management, LLC | 70,000 | $5.28M | 1.16% | +20,000+40.0% | Added |
| Platinum Investment Management Ltd | 69,212 | $5.22M | 1.21% | −24,516−26.2% | Reduced |
| D. E. Shaw & Co., Inc. | 63,250 | $4.77M | 0.00% | −37,320−37.1% | Reduced |
| Swiss National Bank | 62,900 | $4.75M | 0.00% | +19,500+44.9% | Added |
| Simplex Trading, LLC | 62,799 | $4.74M | 0.13% | +62,799 | New |
| Prudential Financial Inc | 54,300 | $4.10M | 0.00% | +41,440+322.2% | Added |
| Blackstone Group Inc. | 51,827 | $3.91M | 0.02% | −138,525−72.8% | Reduced |
| Marshall Wace, LLP | 50,744 | $3.83M | 0.00% | +43,717+622.1% | Added |
| Seven Grand Managers, LLC | 50,000 | $3.77M | 0.29% | +50,000 | New |
| Russell Investments Group, Ltd. | 49,999 | $3.77M | 0.00% | +6,326+14.5% | Added |
| UBS Asset Management Americas Inc | 49,805 | $3.76M | 0.00% | +18,642+59.8% | Added |
| Rafferty Asset Management, LLC | 48,619 | $3.67M | 0.01% | −17,177−26.1% | Reduced |
| Rhumbline Advisers | 45,971 | $3.47M | 0.00% | −1,828−3.8% | Reduced |
| Alps Advisors Inc | 44,922 | $3.39M | 0.02% | +22,416+99.6% | Added |
| Wells Fargo & Company | 42,499 | $3.21M | 0.00% | +20,509+93.3% | Added |
| Banque Pictet & Cie SA | 41,800 | $3.16M | 0.03% | +41,800 | New |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 39,846 | $3.01M | 0.00% | +39,644+19,625.7% | Added |
| Standard Life Aberdeen plc | 36,103 | $2.73M | 0.00% | −18,657−34.1% | Reduced |
| Comerica Bank | 35,872 | $2.71M | 0.01% | +338+1.0% | Added |
| Cinctive Capital Management LP | 33,264 | $2.51M | 0.14% | +33,264 | New |
| Legal & General Group Plc | 32,856 | $2.48M | 0.00% | +5,193+18.8% | Added |
| California State Teachers Retirement System | 30,758 | $2.32M | 0.00% | +9,371+43.8% | Added |
| Tudor Investment Corp Et Al | 30,039 | $2.27M | 0.01% | +30,039 | New |
| Schonfeld Strategic Advisors LLC | 29,145 | $2.20M | 0.01% | +29,145 | New |
| Erste Asset Management GmbH | 24,000 | $1.83M | 0.02% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 22,484 | $1.70M | 0.00% | +12,597+127.4% | Added |
| MetLife Investment Management | 21,311 | $1.61M | 0.01% | +2,073+10.8% | Added |
| SummitTX Capital, L.P. | 20,972 | $1.58M | 0.05% | −5,635−21.2% | Reduced |