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Apogee Therapeutics, Inc.

APGEDelisted Sep 3, 2026
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001974640

Apogee Therapeutics, Inc. was delisted on Sep 3, 2026; its insiders filed their last Form 4 on Sep 3, 2026; 288 institutions reported holding it in 13F filings for Q2 2026, worth $8.93B in total; Soros Fund Management was the only superinvestor holding it.

13F holders, Q4 2025

Institutional positions in Apogee Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
207
+35 vs. Q3 2025
Shares held
69.8M
+10.2M (+17.2%) vs. Q3 2025
Total value
$5.27B
+$2.90B (+122.6%) vs. Q3 2025
New holders
53
86 more added
Sold out
18
46 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting APGE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 207 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 73 institutionsQ4 2023: 85 institutionsQ1 2024: 139 institutionsQ2 2024: 139 institutionsQ3 2024: 139 institutionsQ4 2024: 158 institutionsQ1 2025: 169 institutionsQ2 2025: 183 institutionsQ3 2025: 174 institutionsQ4 2025: 207 institutionsQ1 2026: 224 institutionsQ2 2026: 288 institutions
Value heldQ4 2025: $5.27B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $848.7MQ4 2023: $1.16BQ1 2024: $3.52BQ2 2024: $2.13BQ3 2024: $3.29BQ4 2024: $2.62BQ1 2025: $2.30BQ2 2025: $2.51BQ3 2025: $2.37BQ4 2025: $5.27BQ1 2026: $6.64BQ2 2026: $8.93B
Institutions holding APGE and their total value by quarter
QuarterHoldersValue
Q2 2026288$8.93B
Q1 2026224$6.64B
Q4 2025207$5.27B
Q3 2025174$2.37B
Q2 2025183$2.51B
Q1 2025169$2.30B
Q4 2024158$2.62B
Q3 2024139$3.29B
Q2 2024139$2.13B
Q1 2024139$3.52B
Q4 202385$1.16B
Q3 202373$848.7M
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Apogee Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding APGE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FORA Capital, LLC18,200$1.37M0.17%+18,200New
Profund Advisors LLC18,276$1.38M0.04%+4,105+29.0%Added
Voya Investment Management LLC18,492$1.40M0.00%+9,118+97.3%Added
XTX Topco Ltd19,026$1.44M0.04%+13,174+225.1%Added
B Group, Inc.20,000$1.51M1.12%−15,000−42.9%Reduced
State of Wisconsin Investment Board20,313$1.53M0.00%+12,218+150.9%Added
Mirae Asset Global ETFs Holdings Ltd.20,709$1.56M0.00%+2,130+11.5%Added
SummitTX Capital, L.P.20,972$1.58M0.05%−5,635−21.2%Reduced
MetLife Investment Management21,311$1.61M0.01%+2,073+10.8%Added
New York State Common Retirement Fund22,484$1.70M0.00%+12,597+127.4%Added
Erste Asset Management GmbH24,000$1.83M0.02%00.0%Unchanged
Schonfeld Strategic Advisors LLC29,145$2.20M0.01%+29,145New
Tudor Investment Corp Et Al30,039$2.27M0.01%+30,039New
California State Teachers Retirement System30,758$2.32M0.00%+9,371+43.8%Added
Legal & General Group Plc32,856$2.48M0.00%+5,193+18.8%Added
Cinctive Capital Management LP33,264$2.51M0.14%+33,264New
Comerica Bank35,872$2.71M0.01%+338+1.0%Added
Standard Life Aberdeen plc36,103$2.73M0.00%−18,657−34.1%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.39,846$3.01M0.00%+39,644+19,625.7%Added
Banque Pictet & Cie SA41,800$3.16M0.03%+41,800New
Wells Fargo & Company42,499$3.21M0.00%+20,509+93.3%Added
Alps Advisors Inc44,922$3.39M0.02%+22,416+99.6%Added
Rhumbline Advisers45,971$3.47M0.00%−1,828−3.8%Reduced
Rafferty Asset Management, LLC48,619$3.67M0.01%−17,177−26.1%Reduced
UBS Asset Management Americas Inc49,805$3.76M0.00%+18,642+59.8%Added
Russell Investments Group, Ltd.49,999$3.77M0.00%+6,326+14.5%Added
Seven Grand Managers, LLC50,000$3.77M0.29%+50,000New
Marshall Wace, LLP50,744$3.83M0.00%+43,717+622.1%Added
Blackstone Group Inc.51,827$3.91M0.02%−138,525−72.8%Reduced
Prudential Financial Inc54,300$4.10M0.00%+41,440+322.2%Added
Simplex Trading, LLC62,799$4.74M0.13%+62,799New
Swiss National Bank62,900$4.75M0.00%+19,500+44.9%Added
D. E. Shaw & Co., Inc.63,250$4.77M0.00%−37,320−37.1%Reduced
Platinum Investment Management Ltd69,212$5.22M1.21%−24,516−26.2%Reduced
Boxer Capital Management, LLC70,000$5.28M1.16%+20,000+40.0%Added
Invesco Ltd.70,687$5.34M0.00%+41,549+142.6%Added
SG Americas Securities, LLC73,262$5.53M0.01%−60,964−45.4%Reduced
Nomura Holdings Inc76,898$5.80M0.02%+76,898New
Deutsche Bank AG79,361$5.99M0.00%+2,814+3.7%Added
StemPoint Capital LP80,574$6.08M1.04%+80,574New
Manufacturers Life Insurance Company, The80,832$6.12M0.01%+17,607+27.8%Added
HighVista Strategies LLC89,229$6.74M1.73%−17,878−16.7%Reduced
Granahan Investment Management Inc94,720$7.15M0.31%−37,680−28.5%Reduced
Neuberger Berman Group LLC99,648$7.52M0.01%+99,648New
Two Sigma Investments, LP105,241$7.94M0.01%−17,134−14.0%Reduced
Schroder Investment Management Group105,000$7.95M0.01%−110,846−51.4%Reduced
Victory Capital Management Inc108,267$8.17M0.00%−108,946−50.2%Reduced
ArrowMark Colorado Holdings LLC109,410$8.26M0.18%00.0%Unchanged
Nicholas Investment Partners, LP112,924$8.52M0.62%+112,924New
Bank of New York Mellon Corp118,084$8.91M0.00%+10,544+9.8%Added
Nuveen, LLC121,050$9.14M0.00%+37,759+45.3%Added
Ameriprise Financial Inc122,900$9.28M0.00%+19,748+19.1%Added
Kennedy Capital Management, Inc.124,979$9.43M0.20%+928+0.7%Added
Capital World Investors127,618$9.63M0.00%00.0%Unchanged
Universal- Beteiligungs- und Servicegesellschaft mbH127,629$9.63M0.02%−3,807−2.9%Reduced
Federated Hermes, Inc.127,931$9.66M0.02%+127,931New
TD Asset Management Inc129,290$9.76M0.01%+46,050+55.3%Added
Parkman Healthcare Partners LLC130,069$9.82M0.93%+24,238+22.9%Added
Barclays PLC133,193$10.1M0.00%−509,123−79.3%Reduced
Millennium Management LLC140,727$10.6M0.01%−289,736−67.3%Reduced
Candriam Luxembourg S.C.A.191,318$14.4M0.07%+65,237+51.7%Added
Trails Edge Capital Partners, LP192,000$14.5M3.58%+192,000New
Woodline Partners LP210,466$15.9M0.06%+153,145+267.2%Added
Adage Capital Partners GP, L.L.C.240,000$18.1M0.03%+5,000+2.1%Added
Loomis Sayles & Co L P255,439$19.3M0.02%+255,439New
First Light Asset Management, LLC284,991$21.5M1.64%+284,991New
Pictet Asset Management Holding SA312,883$23.6M0.02%+312,883New
Northern Trust Corp327,376$24.7M0.00%+42,893+15.1%Added
Great Point Partners LLC374,000$28.2M9.15%+70,000+23.0%Added
Charles Schwab Investment Management Inc381,362$28.8M0.00%+61,459+19.2%Added
Opaleye Management Inc.388,257$29.3M3.87%+25,000+6.9%Added
Eventide Asset Management, LLC436,015$32.9M0.51%+436,015New
Franklin Resources Inc451,002$34.0M0.01%−279,759−38.3%Reduced
First Turn Management, LLC474,839$35.8M4.10%+72,028+17.9%Added
Frontier Capital Management Co LLC480,453$36.3M0.38%+106,046+28.3%Added
Avoro Capital Advisors LLC500,000$37.7M0.37%+500,000New
Polar Capital Holdings Plc503,539$38.0M0.17%−20,555−3.9%Reduced
Sofinnova Investments, Inc.534,845$40.4M1.74%−30,572−5.4%Reduced
Vestal Point Capital, LP550,000$41.5M1.52%+125,000+29.4%Added
Goldman Sachs Group Inc565,410$42.7M0.01%−34,206−5.7%Reduced
Novo Holdings A/S570,000$43.0M3.34%+70,000+14.0%Added
Braidwell LP575,067$43.4M1.39%−863,678−60.0%Reduced
Jennison Associates LLC578,627$43.7M0.03%+578,627New
Remedium Capital Partners, LLC583,591$44.0M25.88%+583,591New
Citadel Advisors LLC766,981$57.9M0.04%−402,263−34.4%Reduced
Bank of America Corp793,695$59.9M0.00%+399,783+101.5%Added
Morgan Stanley890,264$67.2M0.00%+425,301+91.5%Added
Mercer Global Advisors Inc890,665$67.2M0.10%−79,916−8.2%Reduced
UBS Group AG974,826$73.6M0.01%+175,361+21.9%Added
Geode Capital Management, LLC1,059,085$80.0M0.00%+166,882+18.7%Added
Alliancebernstein L.P.1,093,657$82.5M0.03%−325,475−22.9%Reduced
Paradigm Biocapital Advisors LP1,123,243$84.8M2.27%−398,514−26.2%Reduced
Affinity Asset Advisors, LLC1,234,926$93.2M6.70%+61,500+5.2%Added
Price T Rowe Associates Inc1,237,135$93.4M0.01%+486,606+64.8%Added
JPMorgan Chase & Co1,373,066$103.6M0.01%+235,335+20.7%Added
State Street Corp1,690,186$127.6M0.00%+34,638+2.1%Added
Fairmount Funds Management LLC2,048,647$154.6M11.77%00.0%Unchanged
Janus Henderson Group PLC2,062,604$155.7M0.07%+1,576,626+324.4%Added
Driehaus Capital Management LLC2,183,704$164.8M1.12%+25,202+1.2%Added
Perceptive Advisors LLC2,330,651$175.9M3.22%+978,662+72.4%Added