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Alto Neuroscience, Inc.

ANRO
Exchange
NYSE
Industry
Pharmaceutical Preparations
SEC CIK
0001999480

No open-market purchases or sales by Alto Neuroscience, Inc. insiders were filed in the last 90 days; 114 institutions reported holding it in 13F filings for Q2 2026, worth $777.6M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Alto Neuroscience, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
97
+21 vs. Q3 2025
Shares held
24.5M
+7.81M (+46.9%) vs. Q3 2025
Total value
$435.9M
+$368.8M (+550.2%) vs. Q3 2025
New holders
30
27 more added
Sold out
9
25 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ANRO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 97 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 53 institutionsQ2 2024: 58 institutionsQ3 2024: 75 institutionsQ4 2024: 77 institutionsQ1 2025: 83 institutionsQ2 2025: 80 institutionsQ3 2025: 77 institutionsQ4 2025: 97 institutionsQ1 2026: 110 institutionsQ2 2026: 114 institutions
Value heldQ4 2025: $435.9M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $245.2MQ2 2024: $198.8MQ3 2024: $265.5MQ4 2024: $95.3MQ1 2025: $45.0MQ2 2025: $38.1MQ3 2025: $67.4MQ4 2025: $435.9MQ1 2026: $602.5MQ2 2026: $777.6M
Institutions holding ANRO and their total value by quarter
QuarterHoldersValue
Q2 2026114$777.6M
Q1 2026110$602.5M
Q4 202597$435.9M
Q3 202577$67.4M
Q2 202580$38.1M
Q1 202583$45.0M
Q4 202477$95.3M
Q3 202475$265.5M
Q2 202458$198.8M
Q1 202453$245.2M
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Alto Neuroscience, Inc.; share changes are against Q3 2025.

Institutions holding ANRO in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Falcon Edge Capital, LP3,707,757$66.0M8.09%00.0%Unchanged
Vestal Point Capital, LP2,485,000$44.2M1.62%+1,535,000+161.6%Added
Commodore Capital LP1,823,196$32.5M2.16%+1,823,196New
Perceptive Advisors LLC1,784,393$31.8M0.58%+1,629,027+1,048.5%Added
Point72 Asset Management, L.P.1,606,954$28.6M0.04%+274,517+20.6%Added
Armistice Capital, LLC1,536,000$27.3M0.67%−100,000−6.1%Reduced
Vanguard Group Inc1,365,847$24.3M0.00%+260,440+23.6%Added
Franklin Resources Inc1,119,578$19.9M0.00%−43,030−3.7%Reduced
Vivo Capital, LLC1,035,551$18.4M1.19%+1,035,551New
72 Investment Holdings, LLC667,778$11.9M23.50%00.0%Unchanged
Millennium Management LLC629,985$11.2M0.01%+314,227+99.5%Added
BlackRock, Inc.607,874$10.8M0.00%+239,995+65.2%Added
Ikarian Capital, LLC515,000$9.17M1.19%+405,000+368.2%Added
Alkeon Capital Management LLC477,101$8.49M0.04%00.0%Unchanged
Northern Trust Corp474,373$8.44M0.00%+13,088+2.8%Added
Integral Health Asset Management, LLC375,000$6.67M0.34%−25,000−6.3%Reduced
Driehaus Capital Management LLC336,762$5.99M0.04%+336,762New
Geode Capital Management, LLC287,435$5.12M0.00%+49,535+20.8%Added
Peapod Lane Capital LLC253,992$4.52M3.85%−27,971−9.9%Reduced
AWM Investment Company, Inc.225,000$4.00M0.39%−55,483−19.8%Reduced
Spruce Street Capital LP222,844$3.97M1.31%+222,844New
Jane Street Group, LLC194,041$3.45M0.00%+145,675+301.2%Added
Marshall Wace, LLP193,109$3.44M0.00%−632,116−76.6%Reduced
Two Sigma Advisers, LP160,100$2.85M0.01%+10,200+6.8%Added
Goldman Sachs Group Inc156,319$2.78M0.00%+66,068+73.2%Added
Two Sigma Investments, LP140,317$2.50M0.00%+23,738+20.4%Added
Boothbay Fund Management, LLC139,304$2.48M0.07%+106,832+329.0%Added
State Street Corp130,665$2.33M0.00%+27,480+26.6%Added
OrbiMed Advisors LLC125,000$2.23M0.05%−125,000−50.0%Reduced
D. E. Shaw & Co., Inc.124,795$2.22M0.00%+124,795New
Susquehanna International Group, LLP118,156$2.10M0.00%−37,520−24.1%Reduced
Qube Research & Technologies Ltd112,792$2.01M0.00%+112,792New
Renaissance Technologies LLC97,399$1.73M0.00%+21,627+28.5%Added
Stifel Financial Corp87,164$1.55M0.00%−34,836−28.6%Reduced
Almitas Capital LLC78,520$1.40M0.31%−116,625−59.8%Reduced
Bridgeway Capital Management, LLC77,653$1.38M0.03%00.0%Unchanged
Ieq Capital, LLC75,294$1.34M0.00%+12,315+19.6%Added
Wellington Management Group LLP69,016$1.23M0.00%+69,016New
Morgan Stanley65,581$1.17M0.00%+4,545+7.4%Added
683 Capital Management, LLC64,782$1.15M0.10%+64,782New
Acadian Asset Management LLC57,546$1.02M0.00%+43,023+296.2%Added
AdvisorShares Investments LLC44,077$784.6K0.13%+44,077New
Allianz Asset Management GmbH43,000$765.4K0.00%+6,000+16.2%Added
Quantinno Capital Management LP35,579$633.3K0.00%00.0%Unchanged
Hudson Bay Capital Management LP34,789$619.2K0.00%+34,789New
SCS Capital Management LLC33,389$594.3K0.01%−33,388−50.0%Reduced
BNP Paribas Arbitrage, SA33,235$591.6K0.00%+32,721+6,366.0%Added
Dimensional Fund Advisors LP31,176$554.9K0.00%+31,176New
Barclays PLC30,392$541.0K0.00%+30,350+72,261.9%Added
Price T Rowe Associates Inc30,228$539.0K0.00%−29,200−49.1%Reduced
Artia Global Partners LP29,192$519.6K0.08%+29,192New
Citizens Financial Group Inc28,190$501.8K0.01%−11,810−29.5%Reduced
Alps Advisors Inc25,505$454.0K0.00%+25,505New
Brown Advisory Inc25,000$445.0K0.00%00.0%Unchanged
University of Texas/Texas Am Investment Managment Co22,175$394.7K0.06%00.0%Unchanged
XTX Topco Ltd20,824$370.7K0.01%+5,078+32.2%Added
AlphaCore Capital LLC20,000$356.0K0.01%+10,000+100.0%Added
ExodusPoint Capital Management, LP18,786$334.4K0.00%+18,786New
UBS Group AG18,489$329.1K0.00%−120,542−86.7%Reduced
Charles Schwab Investment Management Inc17,064$303.7K0.00%+17,064New
JustInvest LLC16,485$293.4K0.00%−560−3.3%Reduced
Ameriprise Financial Inc13,487$240.1K0.00%00.0%Unchanged
Citadel Advisors LLC12,973$230.9K0.00%−24,179−65.1%Reduced
Citigroup Inc12,566$223.7K0.00%+12,566New
Omers Administration Corp12,400$220.7K0.00%+12,400New
Bank of Montreal11,355$202.1K0.00%+13+0.1%Added
Balyasny Asset Management LLC11,120$197.9K0.00%+11,120New
Bank of America Corp11,092$197.4K0.00%+10,968+8,845.2%Added
American Century Companies Inc10,360$184.4K0.00%+10,360New
FMR LLC6,374$113.5K0.00%−1,302−17.0%Reduced
Quest Partners LLC3,821$68.0K0.00%+3,821New
Torren Management, LLC3,484$62.0K0.03%+3,484New
Rothschild Investment LLC2,885$51.4K0.00%00.0%Unchanged
Whittier Trust Co of Nevada Inc2,482$37.4K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,987$35.4K0.00%−403−16.9%Reduced
Group One Trading, L.P.1,413$25.2K0.00%−1,245−46.8%Reduced
The PNC Financial Services Group, Inc.1,307$23.3K0.00%−159−10.8%Reduced
Signaturefd, LLC1,065$19.0K0.00%+1,065New
Federated Hermes, Inc.770$13.7K0.00%−2,577−77.0%Reduced
Wells Fargo & Company765$13.6K0.00%+765New
EverSource Wealth Advisors, LLC661$11.8K0.00%−64−8.8%Reduced
Fortitude Family Office, LLC511$9.10K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC338$6.02K0.00%00.0%Unchanged
Russell Investments Group, Ltd.306$5.45K0.00%00.0%Unchanged
North Star Investment Management Corp.174$3.10K0.00%00.0%Unchanged
CWM, LLC154$3.00K0.00%−770−83.3%Reduced
Global Retirement Partners, LLC150$2.67K0.00%+150New
JPMorgan Chase & Co146$2.60K0.00%+146New
US Bancorp113$2.01K0.00%+113New
Cornerstone Financial Management LLC69$1.23K0.00%+69New
Royal Bank of Canada34$1.00K0.00%−161−82.6%Reduced
Jones Financial Companies LLLP33$5870.00%+33New
Farther Finance Advisors, LLC31$5520.00%+31New
SHP Wealth Management25$4450.00%+25New
Optiver Holding B.V.20$3560.00%00.0%Unchanged
SBI Securities Co., Ltd.12$2140.00%+9+300.0%Added
SRS Capital Advisors, Inc.5$890.00%−37−88.1%Reduced
AQR Capital Management LLC0$00.00%−30,412−100.0%Sold out
Squarepoint Ops LLC0$00.00%−22,816−100.0%Sold out
Bowie Capital Management, LLC0$00.00%−19,484−100.0%Sold out