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Agenus Inc

AGEN
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001098972

No open-market purchases or sales by Agenus Inc insiders were filed in the last 90 days; 103 institutions reported holding it in 13F filings for Q2 2026, worth $43.6M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Agenus Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
96
+12 vs. Q3 2025
Shares held
10.1M
+1.44M (+16.6%) vs. Q3 2025
Total value
$31.8M
−$1.65M (−4.9%) vs. Q3 2025
New holders
22
24 more added
Sold out
10
30 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting AGEN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 96 institutions
Q1 2021: 141 institutionsQ2 2021: 145 institutionsQ3 2021: 167 institutionsQ4 2021: 175 institutionsQ1 2022: 172 institutionsQ2 2022: 150 institutionsQ3 2022: 165 institutionsQ4 2022: 160 institutionsQ1 2023: 161 institutionsQ2 2023: 160 institutionsQ3 2023: 164 institutionsQ4 2023: 173 institutionsQ1 2024: 127 institutionsQ2 2024: 89 institutionsQ3 2024: 98 institutionsQ4 2024: 85 institutionsQ1 2025: 88 institutionsQ2 2025: 92 institutionsQ3 2025: 87 institutionsQ4 2025: 96 institutionsQ1 2026: 88 institutionsQ2 2026: 103 institutions
Value heldQ4 2025: $31.8M
Q1 2021: $316.4MQ2 2021: $634.7MQ3 2021: $631.4MQ4 2021: $431.0MQ1 2022: $333.7MQ2 2022: $284.6MQ3 2022: $336.3MQ4 2022: $423.7MQ1 2023: $315.7MQ2 2023: $341.1MQ3 2023: $246.9MQ4 2023: $189.1MQ1 2024: $119.0MQ2 2024: $148.6MQ3 2024: $45.8MQ4 2024: $23.1MQ1 2025: $13.3MQ2 2025: $40.7MQ3 2025: $33.9MQ4 2025: $31.8MQ1 2026: $30.8MQ2 2026: $43.6M
Institutions holding AGEN and their total value by quarter
QuarterHoldersValue
Q2 2026103$43.6M
Q1 202688$30.8M
Q4 202596$31.8M
Q3 202587$33.9M
Q2 202592$40.7M
Q1 202588$13.3M
Q4 202485$23.1M
Q3 202498$45.8M
Q2 202489$148.6M
Q1 2024127$119.0M
Q4 2023173$189.1M
Q3 2023164$246.9M
Q2 2023160$341.1M
Q1 2023161$315.7M
Q4 2022160$423.7M
Q3 2022165$336.3M
Q2 2022150$284.6M
Q1 2022172$333.7M
Q4 2021175$431.0M
Q3 2021167$631.4M
Q2 2021145$634.7M
Q1 2021141$316.4M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Agenus Inc; share changes are against Q3 2025.

Institutions holding AGEN in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc2,830,736$8.89M0.00%+261,203+10.2%Added
Siren, L.L.C.1,064,250$3.34M0.10%00.0%Unchanged
Acadian Asset Management LLC622,484$1.95M0.00%+417,393+203.5%Added
BlackRock, Inc.558,345$1.75M0.00%+11,233+2.1%Added
Renaissance Technologies LLC543,546$1.71M0.00%+477,346+721.1%Added
Citadel Advisors LLC423,242$1.33M0.00%+423,242New
Geode Capital Management, LLC372,748$1.17M0.00%+25,757+7.4%Added
Morgan Stanley285,198$895.5K0.00%−263,928−48.1%Reduced
Susquehanna International Group, LLP233,674$733.7K0.00%+42,720+22.4%Added
Millennium Management LLC225,339$707.6K0.00%−123,415−35.4%Reduced
Jump Financial, LLC170,407$535.1K0.01%+28,913+20.4%Added
Panagora Asset Management Inc163,148$512.3K0.00%+36,964+29.3%Added
Marshall Wace, LLP146,800$461.0K0.00%+33,487+29.6%Added
Raymond James Financial Inc141,653$444.8K0.00%−4,107−2.8%Reduced
State Street Corp137,383$431.4K0.00%−13,200−8.8%Reduced
D. E. Shaw & Co., Inc.127,638$400.8K0.00%+13,309+11.6%Added
Walleye Capital LLC123,458$387.7K0.00%−187,330−60.3%Reduced
UBS Group AG118,818$373.1K0.00%+36,881+45.0%Added
Two Sigma Investments, LP117,117$367.7K0.00%+14,764+14.4%Added
683 Capital Management, LLC114,336$359.0K0.03%+114,336New
Man Group plc114,204$358.6K0.00%+114,204New
Point72 Asset Management, L.P.108,220$339.8K0.00%+108,220New
Omers Administration Corp100,500$315.6K0.00%+100,500New
Northern Trust Corp89,586$281.3K0.00%+7,888+9.7%Added
Jane Street Group, LLC73,572$231.0K0.00%+20,794+39.4%Added
Connor, Clark & Lunn Investment Management Ltd.67,959$213.4K0.00%+67,959New
Canada Pension Plan Investment Board66,100$207.6K0.00%+66,100New
Goldman Sachs Group Inc61,749$193.9K0.00%+16,034+35.1%Added
Susquehanna Portfolio Strategies, LLC59,413$186.6K0.00%−108,808−64.7%Reduced
Squarepoint Ops LLC55,142$173.1K0.00%+41,179+294.9%Added
ExodusPoint Capital Management, LP47,461$149.0K0.00%+47,461New
Barclays PLC46,273$145.3K0.00%+36,053+352.8%Added
Avestar Capital, LLC41,000$128.7K0.01%00.0%Unchanged
Qube Research & Technologies Ltd39,895$125.3K0.00%+39,895New
Engineers Gate Manager LP35,279$110.8K0.00%+25+0.1%Added
Virtu Financial LLC34,385$108.0K0.00%+34,385New
Two Sigma Advisers, LP34,245$107.5K0.00%+34,245New
Graham Capital Management, L.P.31,706$99.6K0.00%−23,114−42.2%Reduced
Ovata Capital Management Ltd30,800$96.7K0.01%+30,800New
Captrust Financial Advisors30,087$94.5K0.00%−597−1.9%Reduced
Key Client Fiduciary Advisors, LLC27,348$85.9K0.03%−11,885−30.3%Reduced
Advisor Group Holdings, Inc.27,139$85.2K0.00%−6,826−20.1%Reduced
HighTower Advisors, LLC25,142$78.9K0.00%−150−0.6%Reduced
Price T Rowe Associates Inc24,500$77.0K0.00%+24,500New
LPL Financial LLC23,326$73.2K0.00%+3,943+20.3%Added
Group One Trading, L.P.22,239$69.8K0.00%+22,239New
JustInvest LLC19,831$62.3K0.00%−318−1.6%Reduced
Lighthouse Investment Partners, LLC18,720$58.8K0.00%+18,720New
HSBC Holdings PLC17,056$54.2K0.00%00.0%Unchanged
Quadrature Capital Ltd17,121$53.8K0.00%+17,121New
Bank of Montreal16,207$50.9K0.00%+20.0%Added
Sherbrooke Park Advisers LLC15,390$48.3K0.12%−1,167−7.0%Reduced
Charles Schwab Investment Management Inc15,061$47.3K0.00%−50.0%Reduced
Prelude Capital Management, LLC14,500$45.5K0.00%+14,500New
Redwood Family Wealth LLC14,140$44.4K0.04%+14,140New
Bank of America Corp13,246$41.6K0.00%−356,068−96.4%Reduced
R Squared Ltd13,129$41.2K0.02%+13,129New
Post Resch Tallon Group Inc.12,750$40.0K0.03%−7,250−36.3%Reduced
AQR Capital Management LLC11,576$36.3K0.00%−15,703−57.6%Reduced
Values First Advisors, Inc.11,065$34.7K0.02%−2,270−17.0%Reduced
GWM Advisors LLC10,596$33.3K0.00%−33,850−76.2%Reduced
Wells Fargo & Company10,184$32.0K0.00%−3,137−23.5%Reduced
MSA Advisors, LLC10,000$31.4K0.01%00.0%Unchanged
EP Wealth Advisors, LLC10,000$31.4K0.00%+10,000New
Tower Research Capital LLC (TRC)8,402$26.4K0.00%+2,857+51.5%Added
FMR LLC5,429$17.0K0.00%−264−4.6%Reduced
First Command Advisory Services, Inc.3,530$11.1K0.00%00.0%Unchanged
Pinnacle Wealth Planning Services, Inc.3,373$10.6K0.00%+3,373New
Royal Bank of Canada2,129$7.00K0.00%−10,708−83.4%Reduced
CoreCap Advisors, LLC2,000$6.28K0.00%00.0%Unchanged
CWM, LLC1,917$6.00K0.00%−3,044−61.4%Reduced
Optiver Holding B.V.1,373$4.31K0.00%+1,353+6,765.0%Added
Chilton Capital Management LLC1,058$3.32K0.00%00.0%Unchanged
Covestor Ltd1,011$3.00K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co633$1.99K0.00%−75−10.6%Reduced
UMA Financial Services, Inc.621$1.95K0.00%00.0%Unchanged
Game Plan Financial Advisors, LLC585$1.84K0.00%00.0%Unchanged
Rhumbline Advisers538$1.69K0.00%00.0%Unchanged
Huntington National Bank500$1.57K0.00%00.0%Unchanged
Russell Investments Group, Ltd.433$1.36K0.00%−2,784−86.5%Reduced
Nisa Investment Advisors, LLC410$1.29K0.00%00.0%Unchanged
JPMorgan Chase & Co382$1.20K0.00%−28,698−98.7%Reduced
Jones Financial Companies LLLP371$1.17K0.00%00.0%Unchanged
Rialto Wealth Management, LLC305$9580.00%00.0%Unchanged
Fortitude Family Office, LLC296$9290.00%00.0%Unchanged
EverSource Wealth Advisors, LLC274$8600.00%00.0%Unchanged
Atlantic Union Bankshares Corp250$7850.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec100$3140.00%00.0%Unchanged
BNP Paribas Arbitrage, SA96$3010.00%+19+24.7%Added
Allworth Financial LP58$1830.00%+50+625.0%Added
Root Financial Partners, LLC25$790.00%00.0%Unchanged
IFP Advisors, Inc15$470.00%−1−6.3%Reduced
Horizon Financial Services, LLC9$280.00%+9New
SRS Capital Advisors, Inc.5$160.00%−662−99.3%Reduced
SBI Securities Co., Ltd.5$160.00%−301−98.4%Reduced
Parallel Advisors, LLC5$160.00%−19−79.2%Reduced
Torrey Growth & Income Advisors0$00.00%−131,677−100.0%Sold out
Arrowstreet Capital, Limited Partnership0$00.00%−31,054−100.0%Sold out
Simplex Trading, LLC0$00.00%−23,075−100.0%Sold out
Traynor Capital Management, Inc.0$00.00%−13,000−100.0%Sold out