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Actuate Therapeutics, Inc.

ACTU
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001652935

No open-market purchases or sales by Actuate Therapeutics, Inc. insiders were filed in the last 90 days; 62 institutions reported holding it in 13F filings for Q2 2026, worth $20.7M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Actuate Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
45
+2 vs. Q3 2025
Shares held
13.1M
+1.08M (+9.0%) vs. Q3 2025
Total value
$80.2M
−$221.3K (−0.3%) vs. Q3 2025
New holders
8
22 more added
Sold out
6
8 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ACTU on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 45 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 10 institutionsQ4 2024: 19 institutionsQ1 2025: 25 institutionsQ2 2025: 38 institutionsQ3 2025: 43 institutionsQ4 2025: 45 institutionsQ1 2026: 61 institutionsQ2 2026: 62 institutions
Value heldQ4 2025: $80.2M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $2.85MQ4 2024: $80.5MQ1 2025: $70.4MQ2 2025: $68.6MQ3 2025: $80.5MQ4 2025: $80.2MQ1 2026: $38.0MQ2 2026: $20.7M
Institutions holding ACTU and their total value by quarter
QuarterHoldersValue
Q2 202662$20.7M
Q1 202661$38.0M
Q4 202545$80.2M
Q3 202543$80.5M
Q2 202538$68.6M
Q1 202525$70.4M
Q4 202419$80.5M
Q3 202410$2.85M
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Actuate Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding ACTU in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
BIOS Capital Management, LP10,049,996$61.5M74.44%00.0%Unchanged
Voss Capital, LLC1,300,000$7.96M0.42%+403,722+45.0%Added
Vanguard Group Inc529,111$3.24M0.00%+213,101+67.4%Added
BlackRock, Inc.432,041$2.64M0.00%+149,967+53.2%Added
Geode Capital Management, LLC207,744$1.27M0.00%+62,332+42.9%Added
Northern Trust Corp101,423$620.7K0.00%+15,969+18.7%Added
Texas Capital Bank Wealth Management Services Inc94,592$578.9K0.03%+94,592New
State Street Corp56,290$344.5K0.00%+6,395+12.8%Added
Royal Bank of Canada35,263$215.0K0.00%+22,309+172.2%Added
Bridgeway Capital Management, LLC30,982$189.6K0.00%+30,982New
Charles Schwab Investment Management Inc23,841$145.9K0.00%+9,076+61.5%Added
Rock Creek Group, LP21,759$133.2K0.01%+21,759New
Wells Fargo & Company20,146$123.3K0.00%+6,604+48.8%Added
SFMG, LLC20,000$122.4K0.01%+3,000+17.6%Added
Gleason Group, Inc.19,028$116.5K0.01%00.0%Unchanged
Northwestern Mutual Wealth Management Co18,518$113.3K0.00%−783−4.1%Reduced
Jane Street Group, LLC16,625$101.7K0.00%+16,625New
Barclays PLC14,946$91.5K0.00%+6,081+68.6%Added
Morgan Stanley13,119$80.3K0.00%+5,493+72.0%Added
LPL Financial LLC12,965$79.3K0.00%−3,250−20.0%Reduced
Bank of New York Mellon Corp12,565$76.9K0.00%+12,565New
Susquehanna International Group, LLP10,253$62.7K0.00%+10,253New
Rhumbline Advisers9,534$58.3K0.00%+766+8.7%Added
Deutsche Bank AG9,309$57.0K0.00%+8,051+640.0%Added
Bank of America Corp9,061$55.5K0.00%+4,189+86.0%Added
ABS Direct Equity Fund LLC6,597$40.4K0.05%+6,597New
Global Retirement Partners, LLC6,250$38.3K0.00%00.0%Unchanged
New York State Common Retirement Fund6,200$37.9K0.00%00.0%Unchanged
UBS Group AG5,121$31.3K0.00%−3,806−42.6%Reduced
Mirae Asset Global ETFs Holdings Ltd.4,423$27.1K0.00%+1,740+64.9%Added
JPMorgan Chase & Co3,795$23.2K0.00%+1,311+52.8%Added
BNP Paribas Arbitrage, SA2,392$14.6K0.00%+832+53.3%Added
Tower Research Capital LLC (TRC)1,636$10.0K0.00%−7−0.4%Reduced
Legal & General Group Plc1,279$7.83K0.00%+571+80.6%Added
Advisor Group Holdings, Inc.1,000$6.12K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.601$3.68K0.00%00.0%Unchanged
California State Teachers Retirement System585$3.58K0.00%+217+59.0%Added
Russell Investments Group, Ltd.487$2.98K0.00%00.0%Unchanged
Amalgamated Bank298$2.00K0.00%+97+48.3%Added
FMR LLC280$1.71K0.00%−293−51.1%Reduced
Citigroup Inc215$1.32K0.00%−45−17.3%Reduced
Sterling Capital Management LLC40$2450.00%+25+166.7%Added
EverSource Wealth Advisors, LLC2$120.00%−68−97.1%Reduced
True Wealth Design, LLC1$70.00%+1New
CWM, LLC44$00.00%−7−13.7%Reduced
Freestone Capital Holdings, LLC0$00.00%−10,000−100.0%Sold out
Northwestern University0$00.00%−6,488−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−5,000−100.0%Sold out
Prosight Management, LP0$00.00%−885−100.0%Sold out
The PNC Financial Services Group, Inc.0$00.00%−384−100.0%Sold out
SRS Capital Advisors, Inc.0$00.00%−60−100.0%Sold out