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TCG Crossover Management, LLC

SEC CIK
0001839948
Latest filing
Aug 14, 2026

Holdings in Q1 2025

Holdings as of Mar 31, 2025, filed May 14, 2025. Long positions only; changes compare share counts with Q4 2024.

Institution overview
Positions
37
−1 vs. Q4 2024
Portfolio value
$733.1M
−$290.3M (−28.4%) vs. Q4 2024
Filed
May 14, 2025
SEC
Holdings of TCG Crossover Management, LLC in Q1 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
CGONCG Oncology, Inc.COM3,670,206$89.9M12.3%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM6,964,375$41.7M5.7%00.0%UnchangedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS2,890,816$41.6M5.7%00.0%UnchangedHistory
MLYSMineralys Therapeutics, Inc.COM2,470,265$39.2M5.4%00.0%UnchangedHistory
OCULOcular Therapeutix, IncCOM5,319,148$39.0M5.3%00.0%UnchangedHistory
ABVXAbivax S.A.SPONSORED ADS6,056,596$37.9M5.2%00.0%UnchangedHistory
SVRASavara IncCOM12,362,205$34.2M4.7%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM2,650,150$27.7M3.8%00.0%UnchangedHistory
DNTHDianthus Therapeutics, Inc.COM1,501,624$27.2M3.7%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM2,898,103$27.0M3.7%+909,000+45.7%AddedHistory
XNCRXencor IncCOM2,452,138$26.1M3.6%00.0%UnchangedHistory
IRONDisc Medicine, Inc.COM465,257$23.1M3.2%−21,700−4.5%ReducedHistory
TRMLTourmaline Bio, Inc.COM1,477,593$22.5M3.1%00.0%UnchangedHistory
CDTXCidara Therapeutics, Inc.COM NEW1,005,901$21.7M3.0%00.0%UnchangedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM5,943,812$21.0M2.9%+1,300,000+28.0%AddedHistory
SLNOSoleno Therapeutics IncCOM275,000$19.6M2.7%−275,000−50.0%ReducedHistory
EYPTEyePoint, Inc.COM NEW3,572,335$19.4M2.6%00.0%UnchangedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS1,063,000$18.4M2.5%00.0%UnchangedHistory
UPBUpstream Bio, Inc.COM2,801,763$17.1M2.3%00.0%UnchangedHistory
RAPTRAPT Therapeutics, Inc.COM13,090,200$16.0M2.2%−45,060−0.3%ReducedHistory
FULCFulcrum Therapeutics, Inc.COM5,250,000$15.1M2.1%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM2,761,861$14.7M2.0%00.0%UnchangedHistory
TNGXTango Therapeutics, Inc.COM10,736,000$14.7M2.0%00.0%UnchangedHistory
CMPSCOMPASS Pathways plcSPONSORED ADS3,858,000$11.0M1.5%00.0%UnchangedHistory
KURAKura Oncology, Inc.COM1,423,642$9.40M1.3%00.0%UnchangedHistory
THRDThird Harmonic Bio, Inc.COM2,505,424$8.69M1.2%00.0%UnchangedHistory
SLNSilence Therapeutics plcADS3,033,560$8.55M1.2%00.0%UnchangedHistory
ADVMAdverum Biotechnologies, Inc.COM NEW1,796,482$7.85M1.1%00.0%UnchangedHistory
VTGNVistagen Therapeutics, Inc.COM2,676,580$6.69M0.9%00.0%UnchangedHistory
JBIOJade Biosciences, Inc.COM2,240,809$5.62M0.8%00.0%UnchangedHistory
TRDAEntrada Therapeutics, Inc.COM584,955$5.29M0.7%00.0%UnchangedHistory
MBXMBX Biosciences, Inc.COM650,000$4.80M0.7%00.0%UnchangedHistory
AVTXAvalo Therapeutics, Inc.COM NEW483,000$3.87M0.5%00.0%UnchangedHistory
KODKodiak Sciences Inc.COM1,145,538$3.21M0.4%00.0%UnchangedHistory
NKTRNektar TherapeuticsCOM4,000,000$2.72M0.4%00.0%UnchangedHistory
VTYXVentyx Biosciences, Inc.COM316,195$363.6K<0.1%00.0%UnchangedHistory
CABACabaletta Bio, Inc.COM86,795$120.2K<0.1%00.0%UnchangedHistory

Sold out since Q4 2024 (1)

Positions held at the end of Q4 2024 that are gone from this filing.

Positions of TCG Crossover Management, LLC sold out since Q4 2024
SecurityClassShares in Q4 2024Value in Q4 2024% of portfolio in Q4 2024History
KROSKeros Therapeutics, Inc.COM550,000$8.71M0.9%History