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TCG Crossover Management, LLC

SEC CIK
0001839948
Latest filing
Aug 14, 2026

Holdings in Q4 2024

Holdings as of Dec 31, 2024, filed Feb 14, 2025. Long positions only; changes compare share counts with Q3 2024.

Institution overview
Positions
38
+2 vs. Q3 2024
Portfolio value
$1.02B
−$157.0M (−13.3%) vs. Q3 2024
Filed
Feb 14, 2025
SEC
Holdings of TCG Crossover Management, LLC in Q4 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
CGONCG Oncology, Inc.COM3,670,206$105.3M10.3%00.0%UnchangedHistory
DYNDyne Therapeutics, Inc.COM2,650,150$62.4M6.1%00.0%UnchangedHistory
XNCRXencor IncCOM2,452,138$56.4M5.5%+25,000+1.0%AddedHistory
COGTCogent Biosciences, Inc.COM6,964,375$54.3M5.3%00.0%UnchangedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS2,890,816$48.4M4.7%00.0%UnchangedHistory
OCULOcular Therapeutix, IncCOM5,319,148$45.4M4.4%00.0%UnchangedHistory
UPBUpstream Bio, Inc.COM2,801,763$44.9M4.4%+2,801,763NewHistory
ABVXAbivax S.A.SPONSORED ADS6,056,596$44.3M4.3%00.0%UnchangedHistory
SVRASavara IncCOM12,362,205$38.0M3.7%00.0%UnchangedHistory
TNGXTango Therapeutics, Inc.COM10,736,000$33.2M3.2%+10,736,000NewHistory
DNTHDianthus Therapeutics, Inc.COM1,501,624$32.7M3.2%+1,501,624NewHistory
IRONDisc Medicine, Inc.COM486,957$30.9M3.0%00.0%UnchangedHistory
MLYSMineralys Therapeutics, Inc.COM2,470,265$30.4M3.0%00.0%UnchangedHistory
TRMLTourmaline Bio, Inc.COM1,477,593$30.0M2.9%00.0%UnchangedHistory
GPCRStructure Therapeutics Inc.SPONSORED ADS1,063,000$28.8M2.8%00.0%UnchangedHistory
TYRATyra Biosciences, Inc.COM1,989,103$27.6M2.7%00.0%UnchangedHistory
EYPTEyePoint, Inc.COM NEW3,572,335$26.6M2.6%+2,650,000+287.3%AddedHistory
CDTXCidara Therapeutics, Inc.COM NEW1,005,901$26.1M2.5%+1,005,901NewHistory
THRDThird Harmonic Bio, Inc.COM2,505,424$25.8M2.5%+90,424+3.7%AddedHistory
SLNOSoleno Therapeutics IncCOM550,000$24.7M2.4%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM2,761,861$24.7M2.4%00.0%UnchangedHistory
FULCFulcrum Therapeutics, Inc.COM5,250,000$24.7M2.4%00.0%UnchangedHistory
SLNSilence Therapeutics plcADS3,033,560$20.9M2.0%00.0%UnchangedHistory
RAPTRAPT Therapeutics, Inc.COM13,135,260$19.8M1.9%+13,135,260NewHistory
AMLXAmylyx Pharmaceuticals, Inc.COM4,643,812$17.6M1.7%00.0%UnchangedHistory
CMPSCOMPASS Pathways plcSPONSORED ADS3,858,000$14.6M1.4%00.0%UnchangedHistory
KURAKura Oncology, Inc.COM1,423,642$12.4M1.2%00.0%UnchangedHistory
MBXMBX Biosciences, Inc.COM650,000$12.0M1.2%00.0%UnchangedHistory
KODKodiak Sciences Inc.COM1,145,538$11.4M1.1%+137,380+13.6%AddedHistory
TRDAEntrada Therapeutics, Inc.COM584,955$10.1M1.0%00.0%UnchangedHistory
KROSKeros Therapeutics, Inc.COM550,000$8.71M0.9%−329,344−37.5%ReducedHistory
ADVMAdverum Biotechnologies, Inc.COM NEW1,796,482$8.39M0.8%−211,857−10.5%ReducedHistory
VTGNVistagen Therapeutics, Inc.COM2,676,580$7.90M0.8%00.0%UnchangedHistory
JBIOJade Biosciences, Inc.COM2,240,809$5.94M0.6%00.0%UnchangedHistory
NKTRNektar TherapeuticsCOM4,000,000$3.72M0.4%00.0%UnchangedHistory
AVTXAvalo Therapeutics, Inc.COM NEW483,000$3.59M0.4%00.0%UnchangedHistory
VTYXVentyx Biosciences, Inc.COM316,195$692.5K0.1%00.0%UnchangedHistory
CABACabaletta Bio, Inc.COM86,795$197.0K<0.1%00.0%UnchangedHistory

Sold out since Q3 2024 (3)

Positions held at the end of Q3 2024 that are gone from this filing.

Positions of TCG Crossover Management, LLC sold out since Q3 2024
SecurityClassShares in Q3 2024Value in Q3 2024% of portfolio in Q3 2024History
EWTXEdgewise Therapeutics, Inc.COM2,112,984$56.4M4.8%History
TARSTarsus Pharmaceuticals, Inc.COM231,820$7.62M0.6%History
ANTXAN2 Therapeutics, Inc.COM1,555,118$1.66M0.1%History