Skip to main content
Livermore
Livermore
ZHEN

Affinity Asset Advisors, LLC

SEC CIK
0001773195
Latest filing
Aug 13, 2026

Holdings in Q1 2025

Holdings as of Mar 31, 2025, filed May 14, 2025. Long positions only; changes compare share counts with Q4 2024.

Institution overview
Positions
81
+6 vs. Q4 2024
Portfolio value
$638.8M
−$1.35M (−0.2%) vs. Q4 2024
Filed
May 14, 2025
SEC
Holdings of Affinity Asset Advisors, LLC in Q1 2025
SecurityClassSharesValue% of portfolioShare changeActionHistory
Immatics N.V.N44445117*W EXP 07/01/202187,204$2.96K<0.1%00.0%Unchanged–
Rocket Pharmaceuticals, Inc.77313F114*W EXP 09/02/20275,000$3.52K<0.1%00.0%Unchanged–
QTTBQ32 Bio Inc.COM27,777$45.8K<0.1%00.0%UnchangedHistory
ALLKAllakos Inc.COM250,000$56.9K<0.1%+250,000NewHistory
OMEROmeros CorpCOM9,958$81.9K<0.1%00.0%UnchangedHistory
ADGMAdagio Medical Holdings, Inc.COM213,235$169.5K<0.1%00.0%UnchangedHistory
RPTXRepare Therapeutics Inc.COM200,000$197.2K<0.1%+100,000+100.0%AddedHistory
OVIDOvid Therapeutics Inc.COM667,516$208.2K<0.1%+667,516NewHistory
CMPXCompass Therapeutics, Inc.COM130,807$248.5K<0.1%+130,807NewHistory
ZURAZura Bio LtdCLASS A ORD SHS223,335$288.1K<0.1%00.0%UnchangedHistory
RADXRadiopharm Theranostics LtdSPONSORED ADS64,600$310.7K<0.1%−91,571−58.6%ReducedHistory
BDTXBlack Diamond Therapeutics, Inc.COM250,000$387.5K0.1%−309,163−55.3%ReducedHistory
CNTXContext Therapeutics Inc.COM660,589$404.3K0.1%−354,751−34.9%ReducedHistory
STROSutro Biopharma, Inc.COM752,722$489.7K0.1%+752,722NewHistory
VKTXViking Therapeutics, Inc.COM25,000$603.8K0.1%+25,000NewHistory
PCVXVaxcyte, Inc.COM25,000$944.0K0.1%00.0%UnchangedHistory
MGTXMeiraGTx Holdings plcCOM150,000$1.02M0.2%+150,000NewHistory
NXTCNextCure, Inc.COM2,302,598$1.11M0.2%00.0%UnchangedHistory
OLMAOlema Pharmaceuticals, Inc.COM325,000$1.22M0.2%+325,000NewHistory
ABVXAbivax S.A.SPONSORED ADS200,000$1.25M0.2%+200,000NewHistory
ETNB89bio, Inc.COM175,000$1.27M0.2%+175,000NewHistory
THRDThird Harmonic Bio, Inc.COM370,000$1.28M0.2%+370,000NewHistory
MBXMBX Biosciences, Inc.COM175,000$1.29M0.2%+175,000NewHistory
AVRAnteris Technologies Global Corp.COM390,000$1.42M0.2%+90,000+30.0%AddedHistory
NKTXNkarta, Inc.COM800,000$1.47M0.2%00.0%UnchangedHistory
ROIVRoivant Sciences Ltd.SHS150,000$1.51M0.2%+150,000NewHistory
OKUROnKure Therapeutics, Inc.COM CL A394,159$1.69M0.3%+250,000+173.4%AddedHistory
CLYMClimb Bio, Inc.COM1,500,000$1.83M0.3%+1,000,000+200.0%AddedHistory
CGEMCullinan Therapeutics, Inc.COM263,817$2.00M0.3%00.0%UnchangedHistory
JBIOJade Biosciences, Inc.COM800,000$2.01M0.3%00.0%UnchangedHistory
MIRMMirum Pharmaceuticals, Inc.COM49,692$2.24M0.4%−21,050−29.8%ReducedHistory
MNPRMonopar TherapeuticsCOM NEW62,000$2.26M0.4%+62,000NewHistory
GERNGeron CorpCOM1,500,000$2.38M0.4%−750,000−33.3%ReducedHistory
OACCUOaktree Acquisition Corp. III Life SciencesUNIT 10/04/2029250,000$2.60M0.4%00.0%UnchangedHistory
KYMRKymera Therapeutics, Inc.COM100,000$2.74M0.4%+60,000+150.0%AddedHistory
NAMSWNewAmsterdam Pharma Co N.V.*W EXP 11/22/202241,957$2.75M0.4%+4,022+1.7%AddedHistory
MAZEMaze Therapeutics, Inc.COM250,000$2.75M0.4%+250,000NewHistory
AKBAAkebia Therapeutics, Inc.COM1,500,000$2.88M0.5%+1,500,000NewHistory
INZYInozyme Pharma, Inc.COM3,867,710$3.52M0.6%−104,608−2.6%ReducedHistory
SLNOSoleno Therapeutics IncCOM50,000$3.57M0.6%−80,000−61.5%ReducedHistory
FRNMFreenome, Inc.CL A ORD SHS350,000$3.62M0.6%00.0%UnchangedHistory
QUREuniQure N.V.SHS400,000$4.24M0.7%+400,000NewHistory
PRQRProQR Therapeutics N.V.SHS EURO3,284,512$4.37M0.7%+459,512+16.3%AddedHistory
ERASErasca, Inc.COM3,341,519$4.58M0.7%+842,088+33.7%AddedHistory
AUTLAutolus Therapeutics plcSPON ADS3,045,000$4.72M0.7%−1,455,000−32.3%ReducedHistory
CATXPerspective Therapeutics, Inc.COM NEW2,224,196$4.74M0.7%+924,196+71.1%AddedHistory
RZLTRezolute, Inc.COM NEW1,700,000$4.93M0.8%+125,000+7.9%AddedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM152,252$5.11M0.8%−307,748−66.9%ReducedHistory
LXEOLexeo Therapeutics, Inc.COM1,480,881$5.14M0.8%+1,480,881NewHistory
VRDNViridian Therapeutics, Inc.COM390,000$5.26M0.8%+230,386+144.3%AddedHistory
AVTXAvalo Therapeutics, Inc.COM NEW657,154$5.26M0.8%+106,389+19.3%AddedHistory
NBIXNeurocrine Biosciences IncStock50,000$5.53M0.9%+50,000NewHistory
ORKAOruka Therapeutics, Inc.COM545,362$5.60M0.9%+176,664+47.9%AddedHistory
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES325,000$6.65M1.0%−100,000−23.5%ReducedHistory
Travere Therapeutics, Inc.89422GAA5NOTE 2.250% 3/0–$6.99M1.1%–––
IMVTImmunovant, Inc.COM430,000$7.35M1.2%+330,000+330.0%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW481,678$7.77M1.2%−342,650−41.6%ReducedHistory
TRVITrevi Therapeutics, Inc.COM1,250,000$7.86M1.2%+1,250,000NewHistory
VERAVera Therapeutics, Inc.CL A355,143$8.53M1.3%−69,857−16.4%ReducedHistory
NRIXNurix Therapeutics, Inc.COM810,669$9.63M1.5%−129,414−13.8%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM300,000$10.4M1.6%+100,000+50.0%AddedHistory
INSMINSMED IncCOM PAR $.01140,000$10.7M1.7%+90,000+180.0%AddedHistory
ESTAEstablishment Labs Holdings Inc.COM280,000$11.4M1.8%+555+0.2%AddedHistory
Karyopharm Therapeutics Inc.48576UAA4NOTE 3.000%10/1–$11.6M1.8%–––
AXSMAxsome Therapeutics, Inc.COM100,000$11.7M1.8%+25,000+33.3%AddedHistory
MRUSMerus N.V.COM321,962$13.6M2.1%−67,279−17.3%ReducedHistory
Omeros Corp682143AG7NOTE 5.250% 2/1–$14.3M2.2%–––
WVEWave Life Sciences, Inc.SHS1,825,000$14.7M2.3%+325,000+21.7%AddedHistory
SPYSPDR S&P 500 ETF TrustETF30,000$16.8M2.6%+30,000NewHistory
MLYSMineralys Therapeutics, Inc.COM1,100,000$17.5M2.7%+750,000+214.3%AddedHistory
TVTXTravere Therapeutics, Inc.COM1,070,000$19.2M3.0%+870,000+435.0%AddedHistory
PTGXProtagonist Therapeutics, IncCOM400,000$19.3M3.0%+270,000+207.7%AddedHistory
TEVATeva Pharmaceutical Industries LtdSPONSORED ADS1,400,000$21.5M3.4%00.0%UnchangedHistory
CNTACentessa Pharmaceuticals plcSPONSORED ADS1,546,662$22.2M3.5%+450,738+41.1%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM80,000$26.5M4.1%−2,500−3.0%ReducedHistory
NUVLNuvalent, Inc.COM460,000$32.6M5.1%+175,000+61.4%AddedHistory
ALKSAlkermes plc.SHS1,000,000$33.0M5.2%−100,000−9.1%ReducedHistory
ACLXArcellx, Inc.COMMON STOCK530,000$34.8M5.4%+105,000+24.7%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS615,000$39.0M6.1%−45,000−6.8%ReducedHistory
APGEApogee Therapeutics, Inc.COM1,151,199$43.0M6.7%+219,471+23.6%AddedHistory
XENEXenon Pharmaceuticals Inc.COM1,328,175$44.6M7.0%+166,938+14.4%AddedHistory

Options (16)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Affinity Asset Advisors, LLC in Q1 2025
SecurityClassPutsCalls
SPYSPDR S&P 500 ETF TrustETF$223.8M–
iShares Russell 2000 ETF464287655ETF$59.8M–
State Street SPDR S&P Biotech ETF78464A870ETF$40.5M–
AMGNAmgen IncStock–$21.8M
ALNYAlnylam Pharmaceuticals, Inc.COM–$14.9M
PTGXProtagonist Therapeutics, IncCOM–$8.34M
CORTCorcept Therapeutics IncCOM–$8.00M
VERAVera Therapeutics, Inc.CL A–$6.37M
EXELExelixis, Inc.COM–$4.98M
EWTXEdgewise Therapeutics, Inc.COM$4.40M–
NAMSNewAmsterdam Pharma Co N.V.ORDINARY SHARES$1.54M$2.04M
MLYSMineralys Therapeutics, Inc.COM$3.18M–
IBRXImmunityBio, Inc.COM$3.09M–
CMPXCompass Therapeutics, Inc.COM$2.53M–
GALTGalectin Therapeutics IncCOM NEW$2.24M–
TRMLTourmaline Bio, Inc.COM–$1.52M

Sold out since Q4 2024 (14)

Positions held at the end of Q4 2024 that are gone from this filing.

Positions of Affinity Asset Advisors, LLC sold out since Q4 2024
SecurityClassShares in Q4 2024Value in Q4 2024% of portfolio in Q4 2024History
Coherus Biosciences Inc19249HAB9NOTE 1.500% 4/1–$16.2M2.5%–
ARVNArvinas, Inc.COM630,000$12.1M1.9%History
ARWRArrowhead Pharmaceuticals, Inc.COM300,000$5.64M0.9%History
CMPSCOMPASS Pathways plcSPONSORED ADS850,512$3.21M0.5%History
CGONCG Oncology, Inc.COM100,000$2.87M0.4%History
TECXTectonic Therapeutic, Inc.COM58,331$2.69M0.4%History
BBOTBridgeBio Oncology Therapeutics, Inc.CL A ORD SHS250,000$2.63M0.4%History
APLSApellis Pharmaceuticals, Inc.COM50,000$1.60M0.2%History
RAPTRAPT Therapeutics, Inc.COM1,000,000$1.58M0.2%History
NARIInari Medical, Inc.Stock25,000$1.28M0.2%History
SVRASavara IncCOM410,586$1.26M0.2%History
KZRKezar Life Sciences, Inc.COM142,316$956.4K0.1%History
CLDXCelldex Therapeutics, Inc.COM NEW9,992$252.5K<0.1%History
SYRSSyros Pharmaceuticals, Inc.COM NEW150,000$34.5K<0.1%History