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Ghost Tree Capital, LLC

SEC CIK
0001595851
Latest filing
Nov 14, 2024

Holdings in Q2 2022

Holdings as of Jun 30, 2022, filed Aug 15, 2022. Long positions only; changes compare share counts with Q1 2022.

Institution overview
Positions
29
−10 vs. Q1 2022
Portfolio value
$145.5M
−$56.4M (−27.9%) vs. Q1 2022
Filed
Aug 15, 2022
SEC
Holdings of Ghost Tree Capital, LLC in Q2 2022
SecurityClassSharesValue% of portfolioShare changeActionHistory
FOLDAmicus Therapeutics, Inc.COM1,000,000$10.7M7.4%−100,000−9.1%ReducedHistory
APLSApellis Pharmaceuticals, Inc.COM225,000$10.2M7.0%−25,000−10.0%ReducedHistory
SRPTSarepta Therapeutics, Inc.COM130,000$9.74M6.7%+80,000+160.0%AddedHistory
AXSMAxsome Therapeutics, Inc.COM225,000$8.62M5.9%+130,500+138.1%AddedHistory
COGTCogent Biosciences, Inc.COM900,000$8.12M5.6%−800,000−47.1%ReducedHistory
HZNPHorizon Therapeutics Public Ltd CoSHS100,000$7.98M5.5%+100,000NewHistory
MRTXMirati Therapeutics, Inc.COM110,000$7.38M5.1%+90,000+450.0%AddedHistory
PCVXVaxcyte, Inc.COM325,000$7.07M4.9%+25,000+8.3%AddedHistory
ASNDAscendis Pharma A/SSPONSORED ADR75,000$6.97M4.8%−65,000−46.4%ReducedHistory
VRDNViridian Therapeutics, Inc.COM600,000$6.94M4.8%+133,597+28.6%AddedHistory
SGENSeagen Inc.COM35,000$6.19M4.3%+35,000NewHistory
KRTXKaruna Therapeutics, Inc.COM45,000$5.69M3.9%−15,000−25.0%ReducedHistory
MRUSMerus N.V.COM250,000$5.66M3.9%−150,000−37.5%ReducedHistory
ISEEIVERIC bio, Inc.COM500,000$4.81M3.3%+50,000+11.1%AddedHistory
CTICCti Biopharma CorpCOM800,000$4.78M3.3%−500,000−38.5%ReducedHistory
RLMDRelmada Therapeutics, Inc.COM250,000$4.75M3.3%+150,000+150.0%AddedHistory
ARVNArvinas, Inc.COM110,000$4.63M3.2%00.0%UnchangedHistory
SNDXSyndax Pharmaceuticals IncCOM225,000$4.33M3.0%00.0%UnchangedHistory
DSGNDesign Therapeutics, Inc.COM275,000$3.85M2.6%+75,000+37.5%AddedHistory
KZRKezar Life Sciences, Inc.COM450,000$3.72M2.6%+50,000+12.5%AddedHistory
BCRXBiocryst Pharmaceuticals IncCOM325,000$3.44M2.4%−25,000−7.1%ReducedHistory
RAPTRAPT Therapeutics, Inc.COM165,000$3.01M2.1%−85,000−34.0%ReducedHistory
WHWKWhitehawk Therapeutics, Inc.COM150,000$1.85M1.3%00.0%UnchangedHistory
TARSTarsus Pharmaceuticals, Inc.COM120,000$1.75M1.2%00.0%UnchangedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD300,000$1.57M1.1%+300,000NewHistory
NMTR9 Meters Biopharma, Inc.COM1,800,000$469.0K0.3%−1,450,000−44.6%ReducedHistory
SYRESpyre Therapeutics, Inc.COM925,000$467.0K0.3%+238,401+34.7%AddedHistory
DICEDICE Therapeutics, Inc.COM30,000$466.0K0.3%+30,000NewHistory
ALNYAlnylam Pharmaceuticals, Inc.COM1,900$277.0K0.2%+1,900NewHistory

Options (3)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Ghost Tree Capital, LLC in Q2 2022
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF$29.7M$3.71M
CLDXCelldex Therapeutics, Inc.COM NEW–$10.8M
DICEDICE Therapeutics, Inc.COM–$2.33M

Sold out since Q1 2022 (15)

Positions held at the end of Q1 2022 that are gone from this filing.

Positions of Ghost Tree Capital, LLC sold out since Q1 2022
SecurityClassShares in Q1 2022Value in Q1 2022% of portfolio in Q1 2022History
SRRASierra Oncology, Inc.COM NEW325,000$10.4M5.2%History
CLDXCelldex Therapeutics, Inc.COM NEW300,000$10.2M5.1%History
BCYCBicycle Therapeutics PLCSPONSORED ADS100,000$4.39M2.2%History
VRNAVerona Pharma plcSPONSORED ADS750,000$3.74M1.9%History
ZNTLZentalis Pharmaceuticals, Inc.COM80,000$3.69M1.8%History
RCKTRocket Pharmaceuticals, Inc.COM200,000$3.17M1.6%History
XENEXenon Pharmaceuticals Inc.COM100,000$3.06M1.5%History
ACRSAclaris Therapeutics, Inc.COM125,000$2.15M1.1%History
CRNXCrinetics Pharmaceuticals, Inc.COM85,000$1.87M0.9%History
STSASatsuma Pharmaceuticals, Inc.COM473,562$1.80M0.9%History
CYPHCypherpunk Technologies Inc.COM993,714$1.74M0.9%History
VTGNVistagen Therapeutics, Inc.COM NEW1,315,154$1.63M0.8%History
PRDSPardes Biosciences, Inc.COM85,000$614.0K0.3%History
LRMRLarimar Therapeutics, Inc.COM100,000$405.0K0.2%History
PYXSPyxis Oncology, Inc.COMMON STOCK75,000$303.0K0.2%History