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Ghost Tree Capital, LLC

SEC CIK
0001595851
Latest filing
Nov 14, 2024

Holdings in Q2 2021

Holdings as of Jun 30, 2021, filed Aug 11, 2021. Long positions only; changes compare share counts with Q1 2021.

Institution overview
Positions
49
+3 vs. Q1 2021
Portfolio value
$319.8M
−$37.1M (−10.4%) vs. Q1 2021
Filed
Aug 11, 2021
SEC
Holdings of Ghost Tree Capital, LLC in Q2 2021
SecurityClassSharesValue% of portfolioShare changeActionHistory
RAPTRAPT Therapeutics, Inc.COM570,000$18.1M5.7%+570,000NewHistory
ASNDAscendis Pharma A/SSPONSORED ADR135,000$17.8M5.6%00.0%UnchangedHistory
FATEFate Therapeutics IncCOM185,000$16.1M5.0%00.0%UnchangedHistory
XENEXenon Pharmaceuticals Inc.COM850,000$15.8M4.9%00.0%UnchangedHistory
ARVNArvinas, Inc.COM205,000$15.8M4.9%00.0%UnchangedHistory
SNDXSyndax Pharmaceuticals IncCOM875,000$15.0M4.7%−300,000−25.5%ReducedHistory
KURAKura Oncology, Inc.COM700,000$14.6M4.6%+100,000+16.7%AddedHistory
COGTCogent Biosciences, Inc.COM1,600,000$13.0M4.1%00.0%UnchangedHistory
Trillium Therapeutics Inc.89620X506COM NEW1,250,000$12.1M3.8%−700,000−35.9%Reduced–
IOVAIovance Biotherapeutics, Inc.COM450,000$11.7M3.7%−50,000−10.0%ReducedHistory
BIIBBiogen Inc.COM32,500$11.3M3.5%+12,500+62.5%AddedHistory
CLDXCelldex Therapeutics, Inc.COM NEW285,000$9.53M3.0%+35,000+14.0%AddedHistory
MRTXMirati Therapeutics, Inc.COM50,000$8.08M2.5%00.0%UnchangedHistory
ALLOAllogene Therapeutics, Inc.COM275,000$7.17M2.2%+275,000NewHistory
TGTXTG Therapeutics, Inc.COM180,000$6.98M2.2%−20,000−10.0%ReducedHistory
ALDXAldeyra Therapeutics, Inc.COM600,000$6.80M2.1%−50,000−7.7%ReducedHistory
VRNAVerona Pharma plcSPONSORED ADS1,000,000$6.54M2.0%+60,957+6.5%AddedHistory
VRDNViridian Therapeutics, Inc.COM350,000$6.40M2.0%+50,000+16.7%AddedHistory
STSASatsuma Pharmaceuticals, Inc.COM904,225$6.38M2.0%00.0%UnchangedHistory
VTGNVistagen Therapeutics, Inc.COM NEW2,000,000$6.30M2.0%−2,143,702−51.7%ReducedHistory
MRSNMersana Therapeutics, Inc.COM450,000$6.11M1.9%00.0%UnchangedHistory
BCYCBicycle Therapeutics PLCSPONSORED ADS200,000$6.07M1.9%+50,000+33.3%AddedHistory
EPIXESSA Pharma Inc.COM NEW207,500$5.93M1.9%+32,500+18.6%AddedHistory
RCKTRocket Pharmaceuticals, Inc.COM125,000$5.54M1.7%−200,000−61.5%ReducedHistory
MLTXMoonLake ImmunotherapeuticsCOM CL A500,000$5.17M1.6%00.0%UnchangedHistory
LKFTLakefront Biotherapeutics NVSPON ADR75,000$5.17M1.6%+75,000NewHistory
TARSTarsus Pharmaceuticals, Inc.COM170,000$4.93M1.5%+170,000NewHistory
CRNXCrinetics Pharmaceuticals, Inc.COM243,309$4.59M1.4%+243,309NewHistory
ISEEIVERIC bio, Inc.COM725,000$4.58M1.4%−400,000−35.6%ReducedHistory
ACRSAclaris Therapeutics, Inc.COM250,000$4.39M1.4%−350,000−58.3%ReducedHistory
GYREGyre Therapeutics, Inc.COM NEW1,000,000$4.33M1.4%00.0%UnchangedHistory
CTICCti Biopharma CorpCOM1,600,000$4.00M1.3%+850,000+113.3%AddedHistory
SRRASierra Oncology, Inc.COM NEW200,000$3.89M1.2%00.0%UnchangedHistory
HRMYHarmony Biosciences Holdings, Inc.COM125,000$3.53M1.1%+125,000NewHistory
PCVXVaxcyte, Inc.COM145,000$3.26M1.0%+145,000NewHistory
IMUXImmunic, Inc.COM265,000$3.25M1.0%00.0%UnchangedHistory
KDMNKadmon Holdings, Inc.COM800,000$3.10M1.0%+200,000+33.3%AddedHistory
FOLDAmicus Therapeutics, Inc.COM265,000$2.56M0.8%00.0%UnchangedHistory
CRISCuris IncCOM NEW247,124$1.99M0.6%−177,876−41.9%ReducedHistory
CERECerevel Therapeutics Holdings, Inc.COM75,000$1.92M0.6%+75,000NewHistory
CMRXChimerix IncCOM200,000$1.60M0.5%00.0%UnchangedHistory
MRUSMerus N.V.COM75,000$1.58M0.5%+75,000NewHistory
ELEVElevation Acquisition Group Inc.COM100,000$1.36M0.4%+100,000NewHistory
CASICASI Pharmaceuticals, Inc (DE)COM650,000$1.01M0.3%00.0%UnchangedHistory
OTICOtonomy, Inc.COM450,000$1.00M0.3%00.0%UnchangedHistory
LRMRLarimar Therapeutics, Inc.COM100,000$982.0K0.3%+100,000NewHistory
MRNAModerna, Inc.Stock4,000$940.0K0.3%+4,000NewHistory
PRVBProvention Bio, Inc.COM100,000$843.0K0.3%+100,000NewHistory
TBIOTelesis Bio Inc.COM35,000$770.0K0.2%+35,000NewHistory

Options (3)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Ghost Tree Capital, LLC in Q2 2021
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF–$40.6M
IMVTImmunovant, Inc.COM–$2.11M
PRVBProvention Bio, Inc.COM$1.26M–

Sold out since Q1 2021 (11)

Positions held at the end of Q1 2021 that are gone from this filing.

Positions of Ghost Tree Capital, LLC sold out since Q1 2021
SecurityClassShares in Q1 2021Value in Q1 2021% of portfolio in Q1 2021History
APLSApellis Pharmaceuticals, Inc.COM225,000$9.65M2.7%History
iShares Russell 2000 ETF464287655ETF30,000$6.63M1.9%–
CNSTConstellation Pharmaceuticals IncCOM275,000$6.43M1.8%History
BCRXBiocryst Pharmaceuticals IncCOM500,000$5.08M1.4%History
NUVBNuvation Bio Inc.COM CL A500,000$4.96M1.4%History
KYNBKyntra Bio, Inc.COM125,000$4.34M1.2%History
IMVTImmunovant, Inc.COM250,000$4.01M1.1%History
NVAXNovavax IncCOM NEW17,500$3.17M0.9%History
SAGESage Therapeutics, Inc.COM30,000$2.25M0.6%History
DTILPrecision Biosciences IncCOM200,000$2.07M0.6%History
APVOAptevo Therapeutics Inc.COM NEW50,000$1.53M0.4%History