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Livermore
Livermore
ZHEN

EcoR1 Capital, LLC

SEC CIK
0001587114
Latest filing
Aug 14, 2026

Holdings in Q2 2026

Holdings as of Jun 30, 2026, filed Aug 14, 2026. Long positions only; changes compare share counts with Q1 2026.

Institution overview
Positions
31
+2 vs. Q1 2026
Portfolio value
$2.02B
−$323.2M (−13.8%) vs. Q1 2026
Filed
Aug 14, 2026
SEC
Holdings of EcoR1 Capital, LLC in Q2 2026
SecurityClassSharesValue% of portfolioShare changeActionHistory
ZYMEZymeworks Inc.COM22,970,388$600.4M29.8%00.0%UnchangedHistory
ANABAnaptysbio, IncCOM7,880,094$531.9M26.4%00.0%UnchangedHistory
AKTSAktis Oncology, Inc.COM4,824,469$155.5M7.7%00.0%UnchangedHistory
CGONCG Oncology, Inc.COM1,494,300$106.2M5.3%+392,300+35.6%AddedHistory
ETONEton Pharmaceuticals, Inc.COM2,171,938$78.6M3.9%00.0%UnchangedHistory
CRSPCRISPR Therapeutics AGNAMEN AKT1,389,276$75.8M3.8%00.0%UnchangedHistory
ORICOric Pharmaceuticals, Inc.COM6,728,116$72.9M3.6%00.0%UnchangedHistory
TRAXFirst Tracks Biotherapeutics, Inc.ORD SHS3,174,519$63.9M3.2%+3,174,519NewHistory
LKFTLakefront Biotherapeutics NVSPON ADR1,667,119$50.0M2.5%00.0%UnchangedHistory
NGNENeurogene Inc.COM1,271,342$40.0M2.0%00.0%UnchangedHistory
STOKStoke Therapeutics, Inc.COM735,000$24.0M1.2%+635,000+635.0%AddedHistory
FULCFulcrum Therapeutics, Inc.COM6,549,866$24.0M1.2%+6,549,866NewHistory
LEGNLegend Biotech CorpSPONSORED ADS800,000$23.1M1.1%+800,000NewHistory
BBOTBridgeBio Oncology Therapeutics, Inc.COM NEW2,823,126$21.5M1.1%00.0%UnchangedHistory
MBXMBX Biosciences, Inc.COM388,500$21.4M1.1%−388,500−50.0%ReducedHistory
ZBIOZenas BioPharma, Inc.COM789,500$20.0M1.0%00.0%UnchangedHistory
ATRAAtara Biotherapeutics, Inc.COM NEW1,552,000$17.8M0.9%+1,452,407+1,458.3%AddedHistory
RLAYRelay Therapeutics, Inc.COM697,948$13.1M0.6%−1,206,814−63.4%ReducedHistory
AURAAura Biosciences, Inc.COM1,666,667$11.8M0.6%+1,666,667NewHistory
ODTXOdyssey Therapeutics, Inc.COMMON STOCK555,555$10.4M0.5%+555,555NewHistory
EIKNEikon Therapeutics, Inc.COM732,606$9.56M0.5%00.0%UnchangedHistory
PHVSPharvaris N.V.COM235,000$8.13M0.4%+235,000NewHistory
ZURAZura Bio LtdCLASS A ORD SHS1,179,715$6.96M0.3%00.0%UnchangedHistory
PHATPhathom Pharmaceuticals, Inc.COM625,000$6.78M0.3%00.0%UnchangedHistory
NRIXNurix Therapeutics, Inc.COM270,000$6.55M0.3%+270,000NewHistory
ERASErasca, Inc.COM330,000$6.05M0.3%−570,000−63.3%ReducedHistory
ELOXEloxx Pharmaceuticals, Inc.COM NEW400,000$5.55M0.3%+400,000NewHistory
AARDAardvark Therapeutics, Inc.COM396,194$2.28M0.1%+396,194NewHistory
HLXCHelix Acquisition Corp. IIIUSD CL A ORD SHS200,000$2.13M0.1%00.0%UnchangedHistory
MREOMereo BioPharma Group plcSPON ADS1,000,000$317.7K<0.1%−12,368,855−92.5%ReducedHistory
Surrozen, Inc.86889P117*W EXP 08/01/2034,444––00.0%Unchanged–

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of EcoR1 Capital, LLC in Q2 2026
SecurityClassPutsCalls
CGONCG Oncology, Inc.COM–$39.9M
AARDAardvark Therapeutics, Inc.COM–$84.7K

Sold out since Q1 2026 (7)

Positions held at the end of Q1 2026 that are gone from this filing.

Positions of EcoR1 Capital, LLC sold out since Q1 2026
SecurityClassShares in Q1 2026Value in Q1 2026% of portfolio in Q1 2026History
JAZZJazz Pharmaceuticals plcSHS USD1,706,469$322.6M13.8%History
CNTACentessa Pharmaceuticals plcSPONSORED ADS6,000,000$238.3M10.2%History
CRNXCrinetics Pharmaceuticals, Inc.COM4,288,120$155.7M6.7%History
XNCRXencor IncCOM2,183,000$26.3M1.1%History
REPLReplimune Group, Inc.COM1,000,000$7.65M0.3%History
PRLDPrelude Therapeutics IncCOM947,049$3.24M0.1%History
IBIOiBio, Inc.COM NEW1,583,000$3.01M0.1%History