EcoR1 Capital, LLC
- SEC CIK
- 0001587114
- Latest filing
- Aug 14, 2026
Holdings in Q2 2024
Holdings as of Jun 30, 2024, filed Aug 14, 2024. Long positions only; changes compare share counts with Q1 2024.
- Positions
- 55
- −2 vs. Q1 2024
- Portfolio value
- $3.27B
- −$668.4M (−17.0%) vs. Q1 2024
| Security | Class | Shares | Value | % of portfolio | Share change | Action | History |
|---|---|---|---|---|---|---|---|
| APLSApellis Pharmaceuticals, Inc. | COM | 11,607,425 | $445.3M | 13.6% | +250,000+2.2% | Added | History |
| PRTAProthena Corp Public Ltd Co | SHS | 11,584,280 | $239.1M | 7.3% | 00.0% | Unchanged | History |
| SRPTSarepta Therapeutics, Inc. | COM | 1,407,322 | $222.4M | 6.8% | −512,513−26.7% | Reduced | History |
| ANABAnaptysbio, Inc | COM | 7,521,024 | $188.5M | 5.8% | 00.0% | Unchanged | History |
| CRNXCrinetics Pharmaceuticals, Inc. | COM | 4,155,375 | $186.1M | 5.7% | 00.0% | Unchanged | History |
| ARVNArvinas, Inc. | COM | 6,726,491 | $179.1M | 5.5% | 00.0% | Unchanged | History |
| MORFMorphic Holding, Inc. | COM | 4,982,945 | $169.8M | 5.2% | +2,598,561+109.0% | Added | History |
| LKFTLakefront Biotherapeutics NV | SPON ADR | 5,756,268 | $142.6M | 4.4% | 00.0% | Unchanged | History |
| KURAKura Oncology, Inc. | COM | 5,806,871 | $119.6M | 3.7% | 00.0% | Unchanged | History |
| TNGXTango Therapeutics, Inc. | COM | 13,330,736 | $114.4M | 3.5% | 00.0% | Unchanged | History |
| ZYMEZymeworks Inc. | COM | 13,437,473 | $114.4M | 3.5% | 00.0% | Unchanged | History |
| JAZZJazz Pharmaceuticals plc | SHS USD | 1,013,952 | $108.2M | 3.3% | 00.0% | Unchanged | History |
| XNCRXencor Inc | COM | 5,330,416 | $100.9M | 3.1% | 00.0% | Unchanged | History |
| CRSPCRISPR Therapeutics AG | NAMEN AKT | 1,389,276 | $75.0M | 2.3% | 00.0% | Unchanged | History |
| JANXJanux Therapeutics, Inc. | COM | 1,469,818 | $61.6M | 1.9% | +1,469,818 | New | History |
| NUVBNuvation Bio Inc. | COM CL A | 19,209,643 | $56.1M | 1.7% | 00.0% | Unchanged | History |
| CNTACentessa Pharmaceuticals plc | SPONSORED ADS | 5,714,404 | $51.6M | 1.6% | +95,625+1.7% | Added | History |
| ITOSiTeos Therapeutics, Inc. | COM | 3,249,835 | $48.2M | 1.5% | +1,250,586+62.6% | Added | History |
| IMNMImmunome Inc. | COM | 3,879,415 | $46.9M | 1.4% | 00.0% | Unchanged | History |
| NGNENeurogene Inc. | COM | 1,271,342 | $46.3M | 1.4% | 00.0% | Unchanged | History |
| THRDThird Harmonic Bio, Inc. | COM | 3,182,444 | $41.4M | 1.3% | 00.0% | Unchanged | History |
| MRSNMersana Therapeutics, Inc. | COM | 19,364,688 | $38.9M | 1.2% | 00.0% | Unchanged | History |
| VYGRVoyager Therapeutics, Inc. | COM | 3,917,546 | $31.0M | 0.9% | 00.0% | Unchanged | History |
| Avidity Biosciences, Inc.05370A108 | COM | 757,576 | $30.9M | 0.9% | 00.0% | Unchanged | – |
| TCRXTScan Therapeutics, Inc. | COM | 5,000,000 | $29.3M | 0.9% | 00.0% | Unchanged | History |
| ADAPYAdaptimmune Therapeutics PLC | SPONDS ADR | 27,404,070 | $26.7M | 0.8% | 00.0% | Unchanged | History |
| ORICOric Pharmaceuticals, Inc. | COM | 3,418,068 | $24.2M | 0.7% | 00.0% | Unchanged | History |
| CRGXCARGO Therapeutics, Inc. | COM | 1,470,000 | $24.1M | 0.7% | +1,470,000 | New | History |
| CLDXCelldex Therapeutics, Inc. | COM NEW | 650,000 | $24.1M | 0.7% | 00.0% | Unchanged | History |
| PCVXVaxcyte, Inc. | COM | 300,000 | $22.7M | 0.7% | 00.0% | Unchanged | History |
| EWTXEdgewise Therapeutics, Inc. | COM | 1,250,385 | $22.5M | 0.7% | 00.0% | Unchanged | History |
| ACADAcadia Pharmaceuticals Inc | COM | 1,346,475 | $21.9M | 0.7% | −4,645,004−77.5% | Reduced | History |
| LENZLENZ Therapeutics, Inc. | COM | 1,219,774 | $21.1M | 0.6% | 00.0% | Unchanged | History |
| MDGLMadrigal Pharmaceuticals, Inc. | COM | 75,000 | $21.0M | 0.6% | 00.0% | Unchanged | History |
| NMRANeumora Therapeutics, Inc. | COM | 2,071,450 | $20.4M | 0.6% | 00.0% | Unchanged | History |
| BCYCBicycle Therapeutics PLC | SPONSORED ADS | 910,000 | $18.4M | 0.6% | +910,000 | New | History |
| AVIRAtea Pharmaceuticals, Inc. | COM | 5,441,896 | $18.0M | 0.6% | −703,965−11.5% | Reduced | History |
| PHVSPharvaris N.V. | COM | 900,000 | $16.9M | 0.5% | 00.0% | Unchanged | History |
| DYNDyne Therapeutics, Inc. | COM | 427,039 | $15.1M | 0.5% | 00.0% | Unchanged | History |
| TECXTectonic Therapeutic, Inc. | COM | 849,143 | $14.0M | 0.4% | +849,143 | New | History |
| RCKTRocket Pharmaceuticals, Inc. | COM | 508,393 | $10.9M | 0.3% | +508,393 | New | History |
| KROSKeros Therapeutics, Inc. | COM | 187,500 | $8.57M | 0.3% | 00.0% | Unchanged | History |
| KLRSKalaris Therapeutics, Inc. | COM | 11,294,585 | $8.17M | 0.3% | 00.0% | Unchanged | History |
| REPLReplimune Group, Inc. | COM | 850,341 | $7.65M | 0.2% | +850,341 | New | History |
| VERVVerve Therapeutics, Inc. | COM | 1,250,000 | $6.10M | 0.2% | 00.0% | Unchanged | History |
| GBIOGeneration Bio Co. | COM | 2,046,867 | $5.77M | 0.2% | 00.0% | Unchanged | History |
| PRMEPrime Medicine, Inc. | COM | 700,000 | $3.60M | 0.1% | 00.0% | Unchanged | History |
| ATRAAtara Biotherapeutics, Inc. | COM NEW | 406,679 | $3.46M | 0.1% | 00.0% | UnchangedConverted for a 1-for-25 split | History |
| PRQRProQR Therapeutics N.V. | SHS EURO | 2,042,771 | $3.39M | 0.1% | −841,586−29.2% | Reduced | History |
| HOOKHOOKIPA Pharma Inc. | COM | 5,717,324 | $3.38M | 0.1% | +1,122,300+24.4% | Added | History |
| KYTXKyverna Therapeutics, Inc. | COM | 450,000 | $3.38M | 0.1% | 00.0% | Unchanged | History |
| ALGSAligos Therapeutics, Inc. | COM | 6,389,468 | $2.24M | 0.1% | 00.0% | Unchanged | History |
| Nuvation Bio Inc.67080N119 | *W EXP 07/07/202 | 963,333 | – | – | 00.0% | Unchanged | – |
| CareMax, Inc.14171W111 | *W EXP 06/08/202 | 100,000 | – | – | 00.0% | Unchanged | – |
| Surrozen, Inc.86889P117 | *W EXP 08/01/203 | 66,665 | – | – | 00.0% | Unchanged | – |
Sold out since Q1 2024 (8)
Positions held at the end of Q1 2024 that are gone from this filing.
| Security | Class | Shares in Q1 2024 | Value in Q1 2024 | % of portfolio in Q1 2024 | History |
|---|---|---|---|---|---|
| ALECAlector, Inc. | COM | 4,056,548 | $24.4M | 0.6% | History |
| NKTXNkarta, Inc. | COM | 2,000,000 | $21.6M | 0.5% | History |
| OVIDOvid Therapeutics Inc. | COM | 6,117,400 | $18.7M | 0.5% | History |
| GOSSGossamer Bio, Inc. | COM | 9,195,404 | $10.9M | 0.3% | History |
| KODKodiak Sciences Inc. | COM | 1,613,600 | $8.49M | 0.2% | History |
| ARQTArcutis Biotherapeutics, Inc. | COM | 500,000 | $4.96M | 0.1% | History |
| PMVPPMV Pharmaceuticals, Inc. | COM | 566,879 | $963.7K | <0.1% | History |
| ALPNAlpine Immune Sciences, Inc. | COM | 1,000 | $39.6K | <0.1% | History |