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OrbiMed Advisors LLC

SEC CIK
0001055951
Latest filing
Aug 14, 2026

Holdings in Q1 2024

Holdings as of Mar 31, 2024, filed May 15, 2024. Long positions only; changes compare share counts with Q4 2023.

Institution overview
Positions
112
+3 vs. Q4 2023
Portfolio value
$5.11B
+$114.2M (+2.3%) vs. Q4 2023
Filed
May 15, 2024
SEC
Holdings of OrbiMed Advisors LLC in Q1 2024
SecurityClassSharesValue% of portfolioShare changeActionHistory
ALPNAlpine Immune Sciences, Inc.COM2,680,496$106.3M2.1%+145,251+5.7%AddedHistory
BMRNBiomarin Pharmaceutical IncCOM1,278,500$111.7M2.2%−292,910−18.6%ReducedHistory
THCTenet Healthcare CorpCOM NEW1,173,300$123.3M2.4%−51,100−4.2%ReducedHistory
ELVNEnliven Therapeutics, Inc.COM8,998,338$158.3M3.1%00.0%UnchangedHistory
JANXJanux Therapeutics, Inc.COM4,275,553$161.0M3.2%+957,626+28.9%AddedHistory
MRKMerck & Co., Inc.Stock1,316,000$173.6M3.4%+261,000+24.7%AddedHistory
BIIBBiogen Inc.COM900,900$194.3M3.8%+73,300+8.9%AddedHistory
ISRGIntuitive Surgical IncCOM NEW493,100$196.8M3.9%−5,900−1.2%ReducedHistory
BSXBoston Scientific CorpStock3,273,000$224.2M4.4%−33,800−1.0%ReducedHistory
EWTXEdgewise Therapeutics, Inc.COM15,021,721$274.0M5.4%+454,545+3.1%AddedHistory
LLYEli Lilly & CoStock360,800$280.7M5.5%−4,600−1.3%ReducedHistory
SVASinovac Biotech LtdSHS2,718,735––00.0%UnchangedHistory

Options (2)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of OrbiMed Advisors LLC in Q1 2024
SecurityClassPutsCalls
APLSApellis Pharmaceuticals, Inc.COM–$8.82M
SIBNSI-BONE, Inc.COM–$4.09M

Sold out since Q4 2023 (17)

Positions held at the end of Q4 2023 that are gone from this filing.

Positions of OrbiMed Advisors LLC sold out since Q4 2023
SecurityClassShares in Q4 2023Value in Q4 2023% of portfolio in Q4 2023History
RYZBRayzeBio, Inc.COM2,365,213$147.0M2.9%History
Gracell Biotechnologies Inc38406L103SPONSORED ADS9,308,726$93.5M1.9%–
UTHRUnited Therapeutics CorpCOM386,100$84.9M1.7%History
THRXTheseus Pharmaceuticals, Inc.COM17,713,600$71.7M1.4%History
RCMR1 RCM Inc.COM4,803,200$50.8M1.0%History
HUMHumana IncStock109,900$50.3M1.0%History
IOVAIovance Biotherapeutics, Inc.COM4,707,458$38.3M0.8%History
FUSNFusion Pharmaceuticals Inc.COM3,122,770$30.0M0.6%History
ALNYAlnylam Pharmaceuticals, Inc.COM79,400$15.2M0.3%History
QUREuniQure N.V.SHS1,347,900$9.13M0.2%History
GILDGilead Sciences, Inc.Stock100,000$8.10M0.2%History
RAPTRAPT Therapeutics, Inc.COM281,413$6.99M0.1%History
ILMNIllumina, Inc.COM30,300$4.22M0.1%History
AMAMAmbrx Biopharma, Inc.COM296,000$4.22M0.1%History
CLDXCelldex Therapeutics, Inc.COM NEW58,800$2.33M<0.1%History
RCUSArcus Biosciences, Inc.COM117,000$2.23M<0.1%History
AGIOAgios Pharmaceuticals, Inc.COM45,000$1.00M<0.1%History