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OrbiMed Advisors LLC

SEC CIK
0001055951
Latest filing
Aug 14, 2026

Holdings in Q4 2023

Holdings as of Dec 31, 2023, filed Feb 14, 2024. Long positions only; changes compare share counts with Q3 2023.

Institution overview
Positions
109
−11 vs. Q3 2023
Portfolio value
$4.99B
+$671.3M (+15.5%) vs. Q3 2023
Filed
Feb 14, 2024
SEC
Holdings of OrbiMed Advisors LLC in Q4 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
ELVNEnliven Therapeutics, Inc.COM8,998,338$124.5M2.5%00.0%UnchangedHistory
RYZBRayzeBio, Inc.COM2,365,213$147.0M2.9%−257,696−9.8%ReducedHistory
BMRNBiomarin Pharmaceutical IncCOM1,571,410$151.5M3.0%−43,800−2.7%ReducedHistory
EWTXEdgewise Therapeutics, Inc.COM14,567,176$159.4M3.2%00.0%UnchangedHistory
ISRGIntuitive Surgical IncCOM NEW499,000$168.3M3.4%00.0%UnchangedHistory
BSXBoston Scientific CorpStock3,306,800$191.2M3.8%00.0%UnchangedHistory
LLYEli Lilly & CoStock365,400$213.0M4.3%+179,400+96.5%AddedHistory
BIIBBiogen Inc.COM827,600$214.2M4.3%+270,800+48.6%AddedHistory
SVASinovac Biotech LtdSHS2,718,735$340.0M6.8%00.0%UnchangedHistory

Options (1)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of OrbiMed Advisors LLC in Q4 2023
SecurityClassPutsCalls
PFEPfizer IncStock–$14.4M

Sold out since Q3 2023 (25)

Positions held at the end of Q3 2023 that are gone from this filing.

Positions of OrbiMed Advisors LLC sold out since Q3 2023
SecurityClassShares in Q3 2023Value in Q3 2023% of portfolio in Q3 2023History
MRTXMirati Therapeutics, Inc.COM1,959,050$85.3M2.0%History
BAXBaxter International IncStock2,239,900$84.5M2.0%History
CICigna GroupStock231,500$66.2M1.5%History
ABBVAbbVie Inc.Stock330,000$49.2M1.1%History
MDGLMadrigal Pharmaceuticals, Inc.COM253,309$37.0M0.9%History
HZNPHorizon Therapeutics Public Ltd CoSHS266,400$30.8M0.7%History
AKROAkero Therapeutics, Inc.COM350,000$17.7M0.4%History
VTYXVentyx Biosciences, Inc.COM340,384$11.8M0.3%History
ARQTArcutis Biotherapeutics, Inc.COM1,914,479$10.2M0.2%History
SGENSeagen Inc.COM42,600$9.04M0.2%History
GDRXGoodRx Holdings, Inc.COM CL A1,595,000$8.98M0.2%History
MLTXMoonLake ImmunotherapeuticsCLASS A ORD117,000$6.67M0.2%History
KVUEKenvue Inc.Stock312,404$6.27M0.1%History
RLAYRelay Therapeutics, Inc.COM501,966$4.22M0.1%History
CUTRCutera IncCOM603,100$3.63M0.1%History
EPIXESSA Pharma Inc.COM NEW842,366$2.60M0.1%History
KRTXKaruna Therapeutics, Inc.COM14,000$2.37M0.1%History
TDOCTeladoc Health, Inc.COM110,000$2.04M<0.1%History
BCABBioAtla, Inc.COM1,009,279$1.72M<0.1%History
TARAProtara Therapeutics, Inc.COM STK772,584$1.29M<0.1%History
SYBXSynlogic, Inc.COM NEW401,998$1.13M<0.1%History
DMRADamora Therapeutics, Inc.COM924,788$665.4K<0.1%History
XNCRXencor IncCOM19,142$385.7K<0.1%History
ALTAltimmune, Inc.COM NEW100,000$260.0K<0.1%History
HARPHarpoon Therapeutics, Inc.COM NEW62,121$250.3K<0.1%History