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OrbiMed Advisors LLC

SEC CIK
0001055951
Latest filing
Aug 14, 2026

Holdings in Q2 2023

Holdings as of Jun 30, 2023, filed Aug 14, 2023. Long positions only; changes compare share counts with Q1 2023.

Institution overview
Positions
119
+3 vs. Q1 2023
Portfolio value
$5.14B
+$89.3M (+1.8%) vs. Q1 2023
Filed
Aug 14, 2023
SEC
Holdings of OrbiMed Advisors LLC in Q2 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
Vectivbio Hldg AGH9060V101ORD SHS5,156,561$87.7M1.7%00.0%Unchanged–
EVHEvolent Health, Inc.CL A2,895,632$87.7M1.7%00.0%UnchangedHistory
UTHRUnited Therapeutics CorpCOM401,900$88.7M1.7%+401,900NewHistory
IONSIonis Pharmaceuticals IncCOM2,169,500$89.0M1.7%+45,000+2.1%AddedHistory
BMYBristol Myers Squibb CoStock1,488,000$95.2M1.9%−852,000−36.4%ReducedHistory
IRONDisc Medicine, Inc.COM2,269,637$100.8M2.0%00.0%UnchangedHistory
SWTXSpringWorks Therapeutics, Inc.COM4,178,588$109.6M2.1%−320,312−7.1%ReducedHistory
SLRNACELYRIN, Inc.COM5,326,302$111.3M2.2%+5,326,302NewHistory
EWTXEdgewise Therapeutics, Inc.COM14,567,176$112.9M2.2%00.0%UnchangedHistory
UNHUnitedHealth Group IncStock244,000$117.3M2.3%−32,000−11.6%ReducedHistory
BMRNBiomarin Pharmaceutical IncCOM1,615,210$140.0M2.7%00.0%UnchangedHistory
BAXBaxter International IncStock3,375,000$153.8M3.0%+1,813,000+116.1%AddedHistory
HUMHumana IncStock348,700$155.9M3.0%00.0%UnchangedHistory
BIIBBiogen Inc.COM556,800$158.6M3.1%+51,800+10.3%AddedHistory
THRXTheseus Pharmaceuticals, Inc.COM17,233,668$160.8M3.1%00.0%UnchangedHistory
BSXBoston Scientific CorpStock3,379,900$182.8M3.6%−410,100−10.8%ReducedHistory
ELVNEnliven Therapeutics, Inc.COM8,998,338$183.7M3.6%+2,1250.0%AddedHistory
ISRGIntuitive Surgical IncCOM NEW620,500$212.2M4.1%00.0%UnchangedHistory
SVASinovac Biotech LtdSHS2,718,735––00.0%UnchangedHistory

Options (7)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of OrbiMed Advisors LLC in Q2 2023
SecurityClassPutsCalls
BAXBaxter International IncStock–$13.7M
HUMHumana IncStock–$11.2M
THCTenet Healthcare CorpCOM NEW–$8.14M
HZNPHorizon Therapeutics Public Ltd CoSHS$5.14M–
TGTXTG Therapeutics, Inc.COM–$1.14M
MRSNMersana Therapeutics, Inc.COM–$822.5K
NKTRNektar TherapeuticsCOM–$296.2K

Sold out since Q1 2023 (12)

Positions held at the end of Q1 2023 that are gone from this filing.

Positions of OrbiMed Advisors LLC sold out since Q1 2023
SecurityClassShares in Q1 2023Value in Q1 2023% of portfolio in Q1 2023History
KDNYChinook Therapeutics, Inc.COM2,029,300$47.0M0.9%History
Bellus Health Inc New07987C204COM NEW5,108,900$36.8M0.7%–
PGNYProgyny, Inc.COM1,037,912$33.3M0.7%History
AMLXAmylyx Pharmaceuticals, Inc.COM813,500$23.9M0.5%History
State Street SPDR S&P Biotech ETF78464A870ETF274,000$20.9M0.4%–
RXSTRxSight, Inc.COM1,202,833$20.1M0.4%History
BridgeBio Pharma, Inc.10806XAB8NOTE 2.500% 3/1–$9.47M0.2%–
PTGXProtagonist Therapeutics, IncCOM301,000$6.92M0.1%History
NTLAIntellia Therapeutics, Inc.COM164,627$6.14M0.1%History
MREOMereo BioPharma Group plcSPON ADS7,747,891$5.48M0.1%History
NKTRNektar TherapeuticsCOM1,034,059$726.8K<0.1%History
SYRESpyre Therapeutics, Inc.COM1,797,221$521.2K<0.1%History