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Artal Group S.A.

SEC CIK
0001053906
Latest filing
Aug 13, 2026

Holdings in Q2 2023

Holdings as of Jun 30, 2023, filed Aug 11, 2023. Long positions only; changes compare share counts with Q1 2023.

Institution overview
Positions
114
−4 vs. Q1 2023
Portfolio value
$3.12B
+$1.44B (+85.5%) vs. Q1 2023
Filed
Aug 11, 2023
SEC
Holdings of Artal Group S.A. in Q2 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
CAVACava Group, Inc.COM32,007,990$1.31B42.0%+32,007,990NewHistory
LXRXLexicon Pharmaceuticals, Inc.COM NEW117,553,284$269.2M8.6%+27,775,050+30.9%AddedHistory
MORFMorphic Holding, Inc.COM2,139,995$122.7M3.9%+326,046+18.0%AddedHistory
APLSApellis Pharmaceuticals, Inc.COM1,050,067$95.7M3.1%−166,245−13.7%ReducedHistory
MRTXMirati Therapeutics, Inc.COM2,055,181$74.3M2.4%+517,472+33.7%AddedHistory
ONCBeOne Medicines Ltd.ADR412,496$73.5M2.4%−88,839−17.7%ReducedHistory
SRRKScholar Rock Holding CorpCOM9,059,507$68.3M2.2%+31,557+0.3%AddedHistory
RVMDRevolution Medicines, Inc.COM2,401,617$64.2M2.1%+330,629+16.0%AddedHistory
FOLDAmicus Therapeutics, Inc.COM4,562,567$57.3M1.8%+1,036,160+29.4%AddedHistory
CERECerevel Therapeutics Holdings, Inc.COM1,638,858$52.1M1.7%−275,608−14.4%ReducedHistory
SWTXSpringWorks Therapeutics, Inc.COM1,816,620$47.6M1.5%−7290.0%ReducedHistory
CYTKCytokinetics IncCOM NEW1,416,031$46.2M1.5%+49,008+3.6%AddedHistory
KYMRKymera Therapeutics, Inc.COM1,805,346$41.5M1.3%00.0%UnchangedHistory
KRYSKrystal Biotech, Inc.COM349,669$41.1M1.3%−62,413−15.1%ReducedHistory
SLRNACELYRIN, Inc.COM1,821,214$38.1M1.2%+1,821,214NewHistory
SDGRSchrodinger, Inc.COM700,000$34.9M1.1%00.0%UnchangedHistory
AGENAgenus IncCOM NEW15,631,235$25.0M0.8%00.0%UnchangedHistory
DNLIDenali Therapeutics Inc.COM802,899$23.7M0.8%00.0%UnchangedHistory
SAGESage Therapeutics, Inc.COM500,000$23.5M0.8%−250,000−33.3%ReducedHistory
IGMSIGM Biosciences, Inc.COM2,522,244$23.3M0.7%+12,272+0.5%AddedHistory
KLRSKalaris Therapeutics, Inc.COM6,597,167$22.4M0.7%+1,020,000+18.3%AddedHistory
KURAKura Oncology, Inc.COM2,018,056$21.4M0.7%+300,000+17.5%AddedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD400,000$20.4M0.7%+400,000NewHistory
SESea LtdSPONSORD ADS350,000$20.3M0.7%+47,500+15.7%AddedHistory
SEERSeer, Inc.COM CL A4,750,000$20.3M0.6%00.0%UnchangedHistory
VIGLVigil Neuroscience, Inc.COM1,911,191$18.0M0.6%−332,161−14.8%ReducedHistory
GERNGeron CorpCOM5,565,889$17.9M0.6%00.0%UnchangedHistory
ROIVRoivant Sciences Ltd.SHS1,625,000$16.4M0.5%+1,025,000+170.8%AddedHistory
GBIOGeneration Bio Co.COM2,814,191$15.5M0.5%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM1,213,725$15.2M0.5%−460,018−27.5%ReducedHistory
CBIOCrescent Biopharma, Inc.COM8,589,064$14.9M0.5%00.0%UnchangedHistory
IMGNImmunoGen, Inc.COM765,497$14.4M0.5%+765,497NewHistory
OMGAOmega Therapeutics, Inc.COMMON STOCK2,533,045$14.2M0.5%00.0%UnchangedHistory
PTGXProtagonist Therapeutics, IncCOM500,000$13.8M0.4%+500,000NewHistory
VTYXVentyx Biosciences, Inc.COM408,519$13.4M0.4%−127,293−23.8%ReducedHistory
ERASErasca, Inc.COM4,721,194$13.0M0.4%00.0%UnchangedHistory
ALPNAlpine Immune Sciences, Inc.COM1,193,030$12.3M0.4%00.0%UnchangedHistory
IMAImageneBio, Inc.COM1,849,513$12.1M0.4%+300,000+19.4%AddedHistory
FHTXFoghorn Therapeutics Inc.COM1,720,720$12.1M0.4%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM504,978$12.0M0.4%00.0%UnchangedHistory
REPLReplimune Group, Inc.COM500,000$11.6M0.4%00.0%UnchangedHistory
AMAMAmbrx Biopharma Cayman, Inc.SPONSORED ADS702,291$11.6M0.4%00.0%UnchangedHistory
DHRDanaher CorpStock47,500$11.4M0.4%+47,500NewHistory
NTLAIntellia Therapeutics, Inc.COM276,077$11.3M0.4%00.0%UnchangedHistory
WVEWave Life Sciences, Inc.SHS2,870,523$10.4M0.3%−129,477−4.3%ReducedHistory
BDTXBlack Diamond Therapeutics, Inc.COM2,046,517$10.3M0.3%+400,000+24.3%AddedHistory
RNACCartesian Therapeutics, Inc.COM9,136,635$10.2M0.3%+4,253,435+87.1%AddedHistory
MRSNMersana Therapeutics, Inc.COM3,029,555$9.97M0.3%+813,767+36.7%AddedHistory
NTRANatera, Inc.COM200,000$9.73M0.3%00.0%UnchangedHistory
AUPHAurinia Pharmaceuticals Inc.COM1,000,000$9.68M0.3%00.0%UnchangedHistory
SLNSilence Therapeutics plcADS1,700,000$9.35M0.3%+1,194,926+236.6%AddedHistory
DYNDyne Therapeutics, Inc.COM815,085$9.17M0.3%+282,476+53.0%AddedHistory
VORVor Biopharma Inc.COM2,688,015$8.31M0.3%−104,790−3.8%ReducedHistory
OVIDOvid Therapeutics Inc.COM2,500,000$8.20M0.3%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM1,725,000$8.06M0.3%−250,000−12.7%ReducedHistory
RPTXRepare Therapeutics Inc.COM700,000$7.41M0.2%00.0%UnchangedHistory
DAWNDay One Biopharmaceuticals, Inc.Stock500,000$5.97M0.2%+500,000NewHistory
ARAVAravive, Inc.COM4,572,515$5.76M0.2%00.0%UnchangedHistory
VERVVerve Therapeutics, Inc.COM300,000$5.63M0.2%00.0%UnchangedHistory
ITOSiTeos Therapeutics, Inc.COM400,000$5.30M0.2%00.0%UnchangedHistory
BEKEKE Holdings Inc.SPONSORED ADS350,000$5.20M0.2%+75,000+27.3%AddedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,000,000$5.07M0.2%00.0%UnchangedHistory
HOOKHOOKIPA Pharma Inc.COM5,666,410$4.99M0.2%+3,816,794+206.4%AddedHistory
SLDBSolid Biosciences Inc.COM NEW909,219$4.76M0.2%00.0%UnchangedHistory
SYRSSyros Pharmaceuticals, Inc.COM NEW1,475,744$4.65M0.1%00.0%UnchangedHistory
TSMTaiwan Semiconductor Manufacturing Co LtdADR42,500$4.29M0.1%+12,500+41.7%AddedHistory
PFTAPerception Capital Corp. IIICLASS A ORD SHS380,000$3.94M0.1%00.0%UnchangedHistory
ALXOAlx Oncology Holdings IncCOM500,000$3.75M0.1%00.0%UnchangedHistory
GOSSGossamer Bio, Inc.COM3,028,171$3.63M0.1%00.0%UnchangedHistory
LCIDLucid Group, Inc.COM490,000$3.38M0.1%+490,000NewHistory
Avidity Biosciences, Inc.05370A108COM300,000$3.33M0.1%−211,962−41.4%Reduced–
BZKanzhun LtdSPONSORED ADS220,000$3.31M0.1%+220,000NewHistory
TRMLTourmaline Bio, Inc.COM914,262$2.78M0.1%00.0%UnchangedHistory
CGEMCullinan Therapeutics, Inc.COM250,000$2.69M0.1%00.0%UnchangedHistory
STOKStoke Therapeutics, Inc.COM250,000$2.66M0.1%00.0%UnchangedHistory
KRONKronos Bio, Inc.COM1,542,954$2.65M0.1%00.0%UnchangedHistory
NBPNovaBridge BiosciencesSPONSORED ADS850,000$2.54M0.1%00.0%UnchangedHistory
SANASana Biotechnology, Inc.COM400,000$2.38M0.1%00.0%UnchangedHistory
Achilles Therapeutics PLC00449L102SPONSORED ADS2,255,375$2.13M0.1%00.0%Unchanged–
VVisa Inc.Stock7,500$1.78M0.1%+7,500NewHistory
ADAGAdagene Inc.ADS1,000,000$1.48M<0.1%00.0%UnchangedHistory
AMZNAmazon Com IncStock10,000$1.30M<0.1%+10,000NewHistory
XLOXilio Therapeutics, Inc.COM450,000$1.18M<0.1%00.0%UnchangedHistory
IRWDIronwood Pharmaceuticals IncCOM CL A110,532$1.18M<0.1%00.0%UnchangedHistory
MEHCQChrome Holding Co.CLASS A COM661,009$1.16M<0.1%00.0%UnchangedHistory
CRVSCorvus Pharmaceuticals, Inc.COM500,000$1.15M<0.1%00.0%UnchangedHistory
CRISCuris IncCOM NEW1,300,000$1.08M<0.1%00.0%UnchangedHistory
ADAPYAdaptimmune Therapeutics PLCSPONDS ADR1,133,775$1.05M<0.1%+1,133,775NewHistory
MSFTMicrosoft CorpStock3,000$1.02M<0.1%+3,000NewHistory
TSHATaysha Gene Therapies, Inc.COM SHS1,440,882$952.0K<0.1%00.0%UnchangedHistory
HARPHarpoon Therapeutics, Inc.COM1,000,000$710.0K<0.1%00.0%UnchangedHistory
AMDAdvanced Micro Devices IncStock6,000$683.0K<0.1%+6,000NewHistory
UTHRUnited Therapeutics CorpCOM2,971$656.0K<0.1%−310−9.4%ReducedHistory
KRSAKorsana Biosciences, Inc.Stock138,403$570.0K<0.1%+138,403NewHistory
CRWDCrowdStrike Holdings, Inc.Stock3,500$514.0K<0.1%+3,500NewHistory
DDOGDatadog, Inc.CL A COM5,000$492.0K<0.1%+5,000NewHistory
GOOGLAlphabet Inc.Stock4,000$479.0K<0.1%+4,000NewHistory
INKTMiNK Therapeutics, Inc.COM228,216$479.0K<0.1%−61,372−21.2%ReducedHistory
CRBUCaribou Biosciences, Inc.COM105,347$448.0K<0.1%00.0%UnchangedHistory
BMRNBiomarin Pharmaceutical IncCOM5,028$436.0K<0.1%−26,939−84.3%ReducedHistory

Options (4)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Artal Group S.A. in Q2 2023
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF–$83.2M
MRTXMirati Therapeutics, Inc.COM–$9.03M
FOLDAmicus Therapeutics, Inc.COM–$6.28M
MORFMorphic Holding, Inc.COM–$5.73M

Sold out since Q1 2023 (25)

Positions held at the end of Q1 2023 that are gone from this filing.

Positions of Artal Group S.A. sold out since Q1 2023
SecurityClassShares in Q1 2023Value in Q1 2023% of portfolio in Q1 2023History
WWWW International, Inc.COM14,818,300$61.1M3.6%History
FATEFate Therapeutics IncCOM2,600,000$14.8M0.9%History
RXDXPrometheus Biosciences, Inc.COM121,756$13.1M0.8%History
TVTXTravere Therapeutics, Inc.COM511,784$11.5M0.7%History
BBIOBridgeBio Pharma, Inc.COM500,000$8.29M0.5%History
TGTXTG Therapeutics, Inc.COM511,389$7.69M0.5%History
TSVT2seventy bio, Inc.COMMON STOCK750,000$7.65M0.5%History
ETNB89bio, Inc.COM500,000$7.62M0.5%History
KDNYChinook Therapeutics, Inc.COM258,687$5.99M0.4%History
VKTXViking Therapeutics, Inc.COM300,000$5.00M0.3%History
ANNXAnnexon, Inc.COM1,018,303$3.92M0.2%History
IMUXImmunic, Inc.COM1,274,713$1.90M0.1%History
GPCRStructure Therapeutics Inc.SPONSORED ADS75,000$1.78M0.1%History
CYPHCypherpunk Technologies Inc.COM4,000,000$1.36M0.1%History
TCRRTCR2 Therapeutics Inc.COM750,000$1.13M0.1%History
BCRXBiocryst Pharmaceuticals IncCOM67,909$566.0K<0.1%History
MTCRMetacrine, Inc.COM924,898$528.0K<0.1%History
ARVNArvinas, Inc.COM18,108$495.0K<0.1%History
KRTXKaruna Therapeutics, Inc.COM1,747$317.0K<0.1%History
BACBank of America CorpStock8,000$229.0K<0.1%History
AIGAmerican International Group, Inc.Stock4,000$201.0K<0.1%History
PRTAProthena Corp Public Ltd CoSHS2,746$133.0K<0.1%History
DICEDICE Therapeutics, Inc.COM4,318$124.0K<0.1%History
RUBYRubius Therapeutics, Inc.COM2,042,666$44.0K<0.1%History
CFRXCONTRAFECT CorpCOM NEW18,750$34.0K<0.1%History