D. E. Shaw & Co., Inc.

SEC CIK: 0001009207
Latest filing: Aug 14, 2026

SEC filings (opens in a new tab)

UPB holding history

Upstream Bio, Inc. in every 13F filed by D. E. Shaw & Co., Inc., including the quarters it was sold out or no filing was made. Changes compare share counts with the previous calendar quarter.

UPB overview All 13F holders of UPB Full Q2 2026 holdings

Shares (Q2 2026): 1,036,044
Value: $7.17M
% of portfolio: <0.1%
Quarters held: 3; Since Q4 2025

Holdings of UPB by D. E. Shaw & Co., Inc., by quarter
Quarter	Shares	Value	% of portfolio	Share change	Action	All holders
Q2 2026	1,036,044	$7.17M	<0.1%	+215,564+26.3%	Added	Holders
Q1 2026	820,480	$7.38M	<0.1%	+793,389+2,928.6%	Added	Holders
Q4 2025	27,091	$735.5K	<0.1%	+27,091	New	Holders