| Deerfield Management Company, L.P. (Series C) | 3,769,795 | $3,664 萬 | 0.77% | – | – |
| Fred Alger Management, LLC | 3,626,637 | $3,525 萬 | 0.09% | – | – |
| Vanguard Group Inc | 3,538,455 | $3,439 萬 | 0.00% | – | – |
| BlackRock Inc. | 3,100,594 | $3,014 萬 | 0.00% | – | – |
| Camber Capital Management LP | 2,555,000 | $2,484 萬 | 0.99% | – | – |
| State Street Corp | 2,323,155 | $2,258 萬 | 0.00% | – | – |
| Renaissance Technologies LLC | 1,592,235 | $1,548 萬 | 0.02% | – | – |
| Palo Alto Investors LP | 1,392,997 | $1,354 萬 | 0.77% | – | – |
| Great Point Partners LLC | 1,300,000 | $1,264 萬 | 2.61% | – | – |
| Acadian Asset Management LLC | 1,215,477 | $1,181 萬 | 0.05% | – | – |
| AIGH Capital Management LLC | 964,590 | $937.6 萬 | 3.23% | – | – |
| Goldman Sachs Group Inc | 825,462 | $802.4 萬 | 0.00% | – | – |
| Millennium Management LLC | 777,350 | $755.6 萬 | 0.01% | – | – |
| Jupiter Asset Management Ltd | 688,346 | $669.1 萬 | 0.07% | – | – |
| Rice Hall James & Associates, LLC | 605,792 | $588.8 萬 | 0.19% | – | – |
| Geode Capital Management, LLC | 602,388 | $585.5 萬 | 0.00% | – | – |
| Wellington Management Group LLP | 574,778 | $558.7 萬 | 0.00% | – | – |
| Globeflex Capital L P | 428,680 | $416.7 萬 | 0.76% | – | – |
| Bank of America Corp | 408,709 | $397.3 萬 | 0.00% | – | – |
| Northern Trust Corp | 345,611 | $335.9 萬 | 0.00% | – | – |
| Sofinnova Investments, Inc. | 344,917 | $335.3 萬 | 0.21% | – | – |
| Federated Hermes, Inc. | 270,736 | $263.2 萬 | 0.01% | – | – |
| Charles Schwab Investment Management Inc | 267,956 | $260.5 萬 | 0.00% | – | – |
| Ameriprise Financial Inc | 264,092 | $256.4 萬 | 0.00% | – | – |
| Prudential Financial Inc | 256,884 | $249.7 萬 | 0.00% | – | – |
| Nuveen Asset Management, LLC | 244,367 | $237.6 萬 | 0.00% | – | – |
| Worth Venture Partners, LLC | 226,758 | $220.4 萬 | 1.08% | – | – |
| Wells Fargo & Company | 218,156 | $212.0 萬 | 0.00% | – | – |
| Panagora Asset Management Inc | 215,735 | $209.7 萬 | 0.01% | – | – |
| Citadel Advisors LLC | 184,808 | $179.6 萬 | 0.00% | – | – |
| Citigroup Inc | 175,252 | $170.4 萬 | 0.00% | – | – |
| Jacobs Levy Equity Management, Inc | 174,693 | $169.8 萬 | 0.01% | – | – |
| JPMorgan Chase & Co | 165,138 | $160.5 萬 | 0.00% | – | – |
| SEI Investments Co | 152,631 | $148.1 萬 | 0.00% | – | – |
| Bank of New York Mellon Corp | 135,805 | $132.0 萬 | 0.00% | – | – |
| Envestnet Asset Management Inc | 127,762 | $124.2 萬 | 0.00% | – | – |
| Bank of Montreal | 130,791 | $123.4 萬 | 0.00% | – | – |
| Russell Investments Group, Ltd. | 129,429 | $122.8 萬 | 0.00% | – | – |
| Rafferty Asset Management, LLC | 117,717 | $114.4 萬 | 0.01% | – | – |
| Truist Financial Corp | 101,226 | $98.4 萬 | 0.00% | – | – |
| Principal Financial Group Inc | 89,683 | $87.2 萬 | 0.00% | – | – |
| D. E. Shaw & Co., Inc. | 80,196 | $78.0 萬 | 0.00% | – | – |
| Swiss National Bank | 75,830 | $73.7 萬 | 0.00% | – | – |
| Alps Advisors Inc | 72,830 | $70.8 萬 | 0.01% | – | – |
| Virginia Retirement Systems Et Al | 72,600 | $70.6 萬 | 0.01% | – | – |
| PDT Partners, LLC | 71,855 | $69.8 萬 | 0.05% | – | – |
| Barclays PLC | 64,349 | $62.5 萬 | 0.00% | – | – |
| Two Sigma Advisers, LP | 63,400 | $61.6 萬 | 0.00% | – | – |
| STRS Ohio | 63,100 | $61.3 萬 | 0.00% | – | – |
| California Public Employees Retirement System | 62,300 | $60.6 萬 | 0.00% | – | – |
| Macquarie Group Ltd | 61,894 | $60.1 萬 | 0.00% | – | – |
| Alliancebernstein L.P. | 61,700 | $60.0 萬 | 0.00% | – | – |
| ExodusPoint Capital Management, LP | 58,950 | $57.3 萬 | 0.01% | – | – |
| UBS Group AG | 57,336 | $55.7 萬 | 0.00% | – | – |
| Ikarian Capital, LLC | 54,901 | $53.3 萬 | 0.08% | – | – |
| State of Wisconsin Investment Board | 49,900 | $48.5 萬 | 0.00% | – | – |
| Shell Asset Management Co | 48,042 | $46.7 萬 | 0.01% | – | – |
| California State Teachers Retirement System | 46,523 | $45.2 萬 | 0.00% | – | – |
| Susquehanna International Group, LLP | 44,303 | $43.1 萬 | 0.00% | – | – |
| UBS Asset Management Americas Inc | 41,659 | $40.5 萬 | 0.00% | – | – |
| Rhumbline Advisers | 41,489 | $40.3 萬 | 0.00% | – | – |
| HRT Financial LP | 39,799 | $38.6 萬 | 0.00% | – | – |
| Squarepoint Ops LLC | 39,700 | $38.6 萬 | 0.00% | – | – |
| Susquehanna Fundamental Investments, LLC | 39,173 | $38.1 萬 | 0.01% | – | – |
| Credit Suisse AG | 38,778 | $37.6 萬 | 0.00% | – | – |
| Oppenheimer Asset Management Inc. | 38,549 | $37.5 萬 | 0.01% | – | – |
| Morgan Stanley | 36,751 | $35.7 萬 | 0.00% | – | – |
| Zebra Capital Management LLC | 34,243 | $33.3 萬 | 0.37% | – | – |
| Capital Fund Management S.A. | 33,425 | $32.5 萬 | 0.01% | – | – |
| Voya Investment Management LLC | 28,874 | $28.1 萬 | 0.00% | – | – |
| Deutsche Bank AG | 26,182 | $25.4 萬 | 0.00% | – | – |
| Parametric Portfolio Associates LLC | 24,088 | $23.4 萬 | 0.00% | – | – |
| First Quadrant L P | 23,500 | $22.8 萬 | 0.02% | – | – |
| Prospera Financial Services Inc | 21,768 | $21.2 萬 | 0.01% | – | – |
| State Board of Administration of Florida Retirement System | 21,221 | $20.6 萬 | 0.00% | – | – |
| New York State Common Retirement Fund | 21,074 | $20.5 萬 | 0.00% | – | – |
| Engineers Gate Manager LP | 20,300 | $19.7 萬 | 0.01% | – | – |
| Cubist Systematic Strategies, LLC | 20,082 | $19.5 萬 | 0.00% | – | – |
| Manufacturers Life Insurance Company, The | 19,929 | $19.4 萬 | 0.00% | – | – |
| AlphaCentric Advisors LLC | 20,000 | $19.4 萬 | 0.07% | – | – |
| Athanor Capital, LP | 18,164 | $17.7 萬 | 0.01% | – | – |
| American International Group, Inc. | 17,982 | $17.5 萬 | 0.00% | – | – |
| Los Angeles Capital Management LLC | 15,259 | $14.8 萬 | 0.00% | – | – |
| SG Americas Securities, LLC | 14,983 | $14.6 萬 | 0.00% | – | – |
| Price T Rowe Associates Inc | 14,025 | $13.6 萬 | 0.00% | – | – |
| ProShare Advisors LLC | 13,765 | $13.4 萬 | 0.00% | – | – |
| Advisor Group Holdings, Inc. | 13,060 | $12.7 萬 | 0.00% | – | – |
| Diversified Trust Co | 11,652 | $11.3 萬 | 0.00% | – | – |
| Dynamic Technology Lab Private Ltd | 11,657 | $11.3 萬 | 0.01% | – | – |
| Jane Street Group, LLC | 11,257 | $11.0 萬 | 0.00% | – | – |
| Invesco Ltd. | 10,845 | $10.6 萬 | 0.00% | – | – |
| Boothbay Fund Management, LLC | 10,539 | $10.2 萬 | 0.01% | – | – |
| Orion Portfolio Solutions, LLC | 10,342 | $10.1 萬 | 0.00% | – | – |
| Royal Bank of Canada | 8,306 | $8.00 萬 | 0.00% | – | – |
| Metropolitan Life Insurance Co | 7,892 | $7.67 萬 | 0.00% | – | – |
| BNP Paribas Arbitrage, SA | 7,617 | $7.40 萬 | 0.00% | – | – |
| DekaBank Deutsche Girozentrale | 8,000 | $7.40 萬 | 0.00% | – | – |
| Public Employees Retirement Association of Colorado | 7,106 | $6.90 萬 | 0.00% | – | – |
| Legal & General Group Plc | 6,045 | $5.90 萬 | 0.00% | – | – |
| Tower Research Capital LLC (TRC) | 5,918 | $5.80 萬 | 0.00% | – | – |
