| ARK Investment Management LLC大師方舟投資 | 6,281,617 | $1.44 億 | 0.29% | – | – |
| Baillie Gifford & Co | 5,930,551 | $1.36 億 | 0.08% | – | – |
| BlackRock Inc. | 5,124,216 | $1.17 億 | 0.00% | – | – |
| Casdin Capital, LLC | 4,330,000 | $9,911 萬 | 2.95% | – | – |
| Nantahala Capital Management, LLC | 4,191,834 | $9,595 萬 | 5.46% | – | – |
| Vanguard Group Inc | 3,171,816 | $7,260 萬 | 0.00% | – | – |
| Gilder Gagnon Howe & Co LLC | 2,456,793 | $5,624 萬 | 0.30% | – | – |
| Telemark Asset Management, LLC | 2,454,500 | $5,618 萬 | 4.76% | – | – |
| William Blair Investment Management, LLC | 2,353,106 | $5,386 萬 | 0.17% | – | – |
| Wells Fargo & Company | 1,984,609 | $4,543 萬 | 0.01% | – | – |
| Opaleye Management Inc. | 1,400,000 | $3,205 萬 | 4.71% | – | – |
| FMR LLC | 1,325,141 | $3,033 萬 | 0.00% | – | – |
| Goldman Sachs Group Inc | 1,195,364 | $2,736 萬 | 0.01% | – | – |
| State Street Corp | 1,121,324 | $2,567 萬 | 0.00% | – | – |
| Wellington Management Group LLP | 1,071,775 | $2,453 萬 | 0.00% | – | – |
| Ameriprise Financial Inc | 1,022,104 | $2,340 萬 | 0.01% | – | – |
| Janus Henderson Group PLC | 993,787 | $2,275 萬 | 0.01% | – | – |
| Sumitomo Mitsui Trust Holdings, Inc. | 967,672 | $2,215 萬 | 0.01% | – | – |
| Nikko Asset Management Americas, Inc. | 967,672 | $2,215 萬 | 0.11% | – | – |
| Geode Capital Management, LLC | 937,053 | $2,145 萬 | 0.00% | – | – |
| Price T Rowe Associates Inc | 791,032 | $1,811 萬 | 0.00% | – | – |
| First Light Asset Management, LLC | 704,186 | $1,612 萬 | 1.07% | – | – |
| Northern Trust Corp | 656,116 | $1,502 萬 | 0.00% | – | – |
| Bleichroeder LP | 579,116 | $1,326 萬 | 2.24% | – | – |
| Nuveen Asset Management, LLC | 570,138 | $1,305 萬 | 0.00% | – | – |
| Millennium Management LLC | 522,361 | $1,196 萬 | 0.02% | – | – |
| Pura Vida Investments, LLC | 480,935 | $1,101 萬 | 0.76% | – | – |
| Dimensional Fund Advisors LP | 459,057 | $1,053 萬 | 0.00% | – | – |
| Morgan Stanley | 445,305 | $1,019 萬 | 0.00% | – | – |
| Vivo Capital, LLC | 388,144 | $888.5 萬 | 0.31% | – | – |
| Charles Schwab Investment Management Inc | 386,732 | $885.3 萬 | 0.00% | – | – |
| Mirae Asset Global Investments Co., Ltd. | 377,809 | $864.8 萬 | 0.03% | – | – |
| Pier Capital, LLC | 368,023 | $842.4 萬 | 0.80% | – | – |
| Two Sigma Investments, LP | 361,833 | $828.2 萬 | 0.03% | – | – |
| Assenagon Asset Management S.A. | 331,290 | $758.3 萬 | 0.04% | – | – |
| Taylor Frigon Capital Management LLC | 258,681 | $592.1 萬 | 1.83% | – | – |
| Jacob Asset Management of New York LLC | 240,052 | $549.5 萬 | 2.13% | – | – |
| Citadel Advisors LLC | 240,028 | $549.4 萬 | 0.01% | – | – |
| Essex Investment Management Co LLC | 233,180 | $533.7 萬 | 0.65% | – | – |
| Bank of New York Mellon Corp | 214,153 | $490.2 萬 | 0.00% | – | – |
| Canada Pension Plan Investment Board | 185,000 | $423.5 萬 | 0.01% | – | – |
| Two Sigma Advisers, LP | 166,100 | $380.2 萬 | 0.01% | – | – |
| Voloridge Investment Management, LLC | 164,294 | $376.1 萬 | 0.03% | – | – |
| Deutsche Bank AG | 150,794 | $345.1 萬 | 0.00% | – | – |
| Eaton Vance Management | 150,340 | $344.1 萬 | 0.01% | – | – |
| Castleark Management LLC | 143,885 | $329.4 萬 | 0.12% | – | – |
| Swiss National Bank | 128,700 | $294.6 萬 | 0.00% | – | – |
| Legal & General Group Plc | 127,942 | $292.9 萬 | 0.00% | – | – |
| JPMorgan Chase & Co | 119,890 | $274.4 萬 | 0.00% | – | – |
| California Public Employees Retirement System | 117,700 | $269.4 萬 | 0.00% | – | – |
| Susquehanna International Group, LLP | 115,731 | $264.9 萬 | 0.00% | – | – |
| Exchange Traded Concepts, LLC | 115,033 | $263.3 萬 | 0.10% | – | – |
| Conestoga Capital Advisors, LLC | 101,085 | $231.4 萬 | 0.03% | – | – |
| Parkman Healthcare Partners LLC | 100,000 | $228.9 萬 | 0.55% | – | – |
| 1492 Capital Management LLC | 91,910 | $210.4 萬 | 1.21% | – | – |
| Captrust Financial Advisors | 91,611 | $209.7 萬 | 0.02% | – | – |
| PDT Partners, LLC | 90,672 | $207.5 萬 | 0.15% | – | – |
| California State Teachers Retirement System | 87,046 | $199.2 萬 | 0.00% | – | – |
| State of New Jersey Common Pension Fund D | 86,133 | $197.2 萬 | 0.01% | – | – |
| Credit Suisse AG | 85,214 | $195.0 萬 | 0.00% | – | – |
| Pratt Collard Advisory Partners LLC | 67,747 | $155.1 萬 | 1.11% | – | – |
| Lord, Abbett & Co. LLC | 66,352 | $151.9 萬 | 0.00% | – | – |
| Barclays PLC | 64,681 | $148.2 萬 | 0.00% | – | – |
| Rhumbline Advisers | 64,567 | $147.8 萬 | 0.00% | – | – |
| Alliancebernstein L.P. | 61,000 | $139.6 萬 | 0.00% | – | – |
| Skandinaviska Enskilda Banken AB (publ) | 60,163 | $137.7 萬 | 0.01% | – | – |
| Susquehanna Fundamental Investments, LLC | 56,449 | $129.2 萬 | 0.02% | – | – |
| Blair William & Co | 54,825 | $125.5 萬 | 0.00% | – | – |
| TD Asset Management Inc | 54,055 | $123.7 萬 | 0.00% | – | – |
| UBS Asset Management Americas Inc | 48,482 | $111.0 萬 | 0.00% | – | – |
| New York State Common Retirement Fund | 47,500 | $108.7 萬 | 0.00% | – | – |
| White Pine Capital LLC | 45,224 | $103.5 萬 | 0.33% | – | – |
| STRS Ohio | 44,000 | $100.7 萬 | 0.00% | – | – |
| D. E. Shaw & Co., Inc. | 42,749 | $97.9 萬 | 0.00% | – | – |
| Migdal Insurance & Financial Holdings Ltd. | 39,797 | $91.1 萬 | 0.01% | – | – |
| Coastal Investment Management, L.P. | 39,000 | $89.3 萬 | 1.55% | – | – |
| Bradley Foster & Sargent Inc | 34,464 | $78.9 萬 | 0.02% | – | – |
| American International Group, Inc. | 33,635 | $77.0 萬 | 0.00% | – | – |
| Manufacturers Life Insurance Company, The | 32,910 | $75.3 萬 | 0.00% | – | – |
| Parametric Portfolio Associates LLC | 30,986 | $70.9 萬 | 0.00% | – | – |
| Bank of America Corp | 30,093 | $68.8 萬 | 0.00% | – | – |
| Royal Bank of Canada | 28,456 | $65.2 萬 | 0.00% | – | – |
| Algert Global LLC | 28,338 | $64.9 萬 | 0.21% | – | – |
| State Board of Administration of Florida Retirement System | 28,012 | $64.1 萬 | 0.00% | – | – |
| Neuberger Berman Group LLC | 27,725 | $63.5 萬 | 0.00% | – | – |
| SG Americas Securities, LLC | 25,834 | $59.1 萬 | 0.00% | – | – |
| Union Square Park Capital Management, LLC | 25,000 | $57.2 萬 | 0.32% | – | – |
| MetLife Investment Management | 24,613 | $56.3 萬 | 0.01% | – | – |
| Voya Investment Management LLC | 24,307 | $55.6 萬 | 0.00% | – | – |
| ProShare Advisors LLC | 24,205 | $55.4 萬 | 0.00% | – | – |
| BNP Paribas Arbitrage, SA | 23,820 | $54.5 萬 | 0.00% | – | – |
| Cubist Systematic Strategies, LLC | 23,662 | $54.2 萬 | 0.01% | – | – |
| Natixis | 23,100 | $52.9 萬 | 0.00% | – | – |
| Squarepoint Ops LLC | 22,648 | $51.8 萬 | 0.00% | – | – |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 22,490 | $51.5 萬 | 0.00% | – | – |
| Guggenheim Capital LLC | 21,350 | $48.9 萬 | 0.00% | – | – |
| Allianz Asset Management GmbH | 21,284 | $48.7 萬 | 0.00% | – | – |
| Aigen Investment Management, LP | 21,237 | $48.6 萬 | 0.06% | – | – |
| Citigroup Inc | 21,103 | $48.3 萬 | 0.00% | – | – |
| Burney Co | 20,000 | $45.8 萬 | 0.02% | – | – |
