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Zenas BioPharma, Inc.

ZBIO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001953926

No open-market purchases or sales by Zenas BioPharma, Inc. insiders were filed in the last 90 days; 144 institutions reported holding it in 13F filings for Q2 2026, worth $1.55B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Zenas BioPharma, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
119
+39 vs. Q3 2025
Shares held
42.8M
+8.00M (+23.0%) vs. Q3 2025
Total value
$1.55B
+$776.2M (+100.2%) vs. Q3 2025
New holders
47
37 more added
Sold out
8
24 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ZBIO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 119 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 0 institutionsQ3 2023: 0 institutionsQ4 2023: 0 institutionsQ1 2024: 0 institutionsQ2 2024: 0 institutionsQ3 2024: 44 institutionsQ4 2024: 65 institutionsQ1 2025: 67 institutionsQ2 2025: 73 institutionsQ3 2025: 80 institutionsQ4 2025: 119 institutionsQ1 2026: 140 institutionsQ2 2026: 144 institutions
Value heldQ4 2025: $1.55B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $0Q3 2023: $0Q4 2023: $0Q1 2024: $0Q2 2024: $0Q3 2024: $418.5MQ4 2024: $259.6MQ1 2025: $256.7MQ2 2025: $330.0MQ3 2025: $774.5MQ4 2025: $1.55BQ1 2026: $1.14BQ2 2026: $1.55B
Institutions holding ZBIO and their total value by quarter
QuarterHoldersValue
Q2 2026144$1.55B
Q1 2026140$1.14B
Q4 2025119$1.55B
Q3 202580$774.5M
Q2 202573$330.0M
Q1 202567$256.7M
Q4 202465$259.6M
Q3 202444$418.5M
Q2 20240$0
Q1 20240$0
Q4 20230$0
Q3 20230$0
Q2 20230$0
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Zenas BioPharma, Inc.; share changes are against Q3 2025.

Institutions holding ZBIO in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Rock Springs Capital Management LP502,077$18.2M0.94%−78,600−13.5%Reduced
Geode Capital Management, LLC588,393$21.4M0.00%+118,358+25.2%Added
Pivotal bioVenture Partners Investment Advisor LLC591,991$21.5M8.31%−187,054−24.0%Reduced
ArrowMark Colorado Holdings LLC751,161$27.3M0.60%−73,507−8.9%Reduced
EcoR1 Capital, LLC789,500$28.7M1.31%+789,500New
Vivo Capital, LLC853,495$31.0M2.00%−329,765−27.9%Reduced
Wellington Management Group LLP855,334$31.1M0.01%−2,190−0.3%Reduced
Polar Capital Holdings Plc1,057,609$38.4M0.18%+1,057,609New
Royalty Pharma Sub-Manager, LLC1,263,150$45.9M26.77%+1,263,150New
Novo Holdings A/S1,450,000$52.6M4.09%−550,000−27.5%Reduced
Vanguard Group Inc1,453,065$52.8M0.00%+290,307+25.0%Added
BlackRock, Inc.1,767,518$64.2M0.00%+538,877+43.9%Added
NVP Associates, LLC1,838,482$66.8M26.16%00.0%Unchanged
Fairmount Funds Management LLC2,209,025$80.2M6.11%+316,219+16.7%Added
Federated Hermes, Inc.2,715,578$98.6M0.16%+853,740+45.9%Added
NEA Management Company, LLC3,523,219$127.9M6.52%+789,500+28.9%Added
Enavate Sciences GP, LLC3,919,159$142.3M28.08%+157,800+4.2%Added
Sr One Capital Management, LP5,037,854$182.9M25.90%+126,315+2.6%Added
FMR LLC7,704,255$279.7M0.01%+2,883,885+59.8%Added
Deerfield Management Company, L.P. (Series C)0$00.00%−1,562,942−100.0%Sold out
Sectoral Asset Management Inc0$00.00%−152,025−100.0%Sold out
Summit Wealth Group LLC0$00.00%−51,356−100.0%Sold out
StemPoint Capital LP0$00.00%−38,742−100.0%Sold out
Birchview Capital, LP0$00.00%−16,500−100.0%Sold out
American Century Companies Inc0$00.00%−10,981−100.0%Sold out
Quarry LP0$00.00%−1,134−100.0%Sold out
SBI Securities Co., Ltd.0$00.00%−1−100.0%Sold out