| Nov 19, 2025 (view filing) | Nov 17 | 2 days | Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.50K | $434.58 | −$1.09M | −12.9%16.9K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 17, 2025 (view filing) | Nov 13-14 | 4 days | Leiden Jeffrey MExecutive Chairman | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −73.3K | $440.60 | −$32.3M | −75.3%24.0K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 3, 2025 (view filing) | Oct 2 | 1 day | Biller JonathanEVP and Chief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −694 | $404.21 | −$280.5K | −4.2%15.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 29, 2025 (view filing) | Aug 27 | 2 days | Bhatia Sangeeta N.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −266 | $386.69 | −$102.9K | −5.5%4.57K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 7, 2025 (view filing) | Aug 6 | 1 day | Kewalramani ReshmaCEO & President | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +10.0K | $389.58 | +$3.90M | +9.4%116.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 7, 2025 (view filing) | Aug 6 | 1 day | Sachs Bruce IDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +5.00K | $389.68 | +$1.95M | +12.5%45.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| May 19, 2025 (view filing) | May 15 | 4 days | Altshuler DavidEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52 | $424.69 | −$22.1K | −0.2%23.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 5, 2025 (view filing) | May 2 | 3 days | Bhatia Sangeeta N.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −400 | $505.86 | −$202.3K | −7.6%4.83K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 17, 2025 (view filing) | Mar 13 | 4 days | Altshuler DavidEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.23K | $510.00 | −$1.65M | −12.2%23.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 12, 2025 (view filing) | Mar 10 | 2 days | Wagner Charles F JrEVP & Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.30K | $500.00 | −$1.65M | −6.0%51.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 12, 2025 (view filing) | Mar 10 | 2 days | Tatsis OuraniaEVP, Chief Reg. & Quality Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.24K | $499.99 | −$1.62M | −6.0%51.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 12, 2025 (view filing) | Mar 10 | 2 days | Altshuler DavidEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.23K | $500.00 | −$1.62M | −10.9%26.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 6, 2025 (view filing) | Mar 4 | 2 days | Tatsis OuraniaEVP, Chief Reg. & Quality Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.06K | $485.49 | −$1.97M | −6.9%54.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 5, 2025 (view filing) | Mar 3 | 2 days | Altshuler DavidEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.23K | $490.00 | −$1.58M | −9.8%29.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 28, 2025 (view filing) | Feb 27 | 1 day | Tatsis OuraniaEVP, Chief Reg. & Quality Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −530 | $475.34 | −$251.9K | −0.9%58.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 28, 2025 (view filing) | Feb 27 | 1 day | Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.65K | $475.34 | −$1.26M | −12.0%19.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 28, 2025 (view filing) | Feb 27 | 1 day | Altshuler DavidEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.27K | $480.00 | −$610.6K | −3.7%33.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 26, 2025 (view filing) | Feb 25 | 1 day | Tatsis OuraniaEVP, Chief Reg. & Quality Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −354 | $480.95 | −$170.3K | −0.5%64.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 26, 2025 (view filing) | Feb 25 | 1 day | Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.77K | $480.95 | −$849.8K | −6.7%24.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 26, 2025 (view filing) | Feb 25 | 1 day | Ambrose KristenSVP & Chief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −884 | $480.95 | −$425.2K | −8.9%9.09K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 26, 2025 (view filing) | Feb 25 | 1 day | Altshuler DavidEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −848 | $480.95 | −$407.8K | −2.1%40.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 24, 2025 (view filing) | Feb 20 | 4 days | Altshuler DavidEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.11K | $480.00 | −$533.3K | −2.4%45.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 19, 2025 (view filing) | Feb 18 | 1 day | Tatsis OuraniaEVP, Chief Reg. & Quality Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −244 | $455.06 | −$111.0K | −0.4%67.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 19, 2025 (view filing) | Feb 18 | 1 day | Biller JonathanEVP and Chief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.66K | $455.06 | −$754.0K | −8.6%17.6K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 19, 2025 (view filing) | Feb 18 | 1 day | Ambrose KristenSVP & Chief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −671 | $455.06 | −$305.3K | −5.9%10.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 11 | 1 day | Tatsis OuraniaEVP, Chief Reg. & Quality Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −310 | $459.83 | −$142.5K | −0.5%64.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 11 | 1 day | Biller JonathanEVP and Chief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.43K | $459.87 | −$1.58M | −17.4%16.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 11 | 1 day | Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.75K | $459.83 | −$803.3K | −7.0%23.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 11 | 1 day | Ambrose KristenSVP & Chief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.38K | $459.83 | −$632.7K | −12.1%9.95K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 19, 2024 (view filing) | Nov 15 | 4 days | Altshuler DavidEVP, Chief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15 | $478.56 | −$7.18K | −0.1%25.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 13, 2024 (view filing) | Nov 11 | 2 days | Wagner Charles F JrEVP & Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.00K | $518.27 | −$1.55M | −6.4%44.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Nov 12, 2024 (view filing) | Nov 8 | 4 days | Kewalramani ReshmaCEO & President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.2K | $515.00 | −$7.83M | −16.7%75.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Oct 3, 2024 (view filing) | Oct 2 | 1 day | Biller JonathanEVP and Chief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −999 | $461.66 | −$461.2K | −5.7%16.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 4, 2024 (view filing) | Aug 30 | 5 days | Leiden Jeffrey MExecutive Chairman | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.78K | $499.00 | −$1.89M | −27.5%9.99K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Sep 4, 2024 (view filing) | Aug 30 | 5 days | Bhatia Sangeeta N.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −646 | $500.00 | −$323.0K | −12.7%4.43K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 12, 2024 (view filing) | Aug 8 | 4 days | Bhatia Sangeeta N.Director | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.29K | $466.29 | −$602.4K | −22.6%4.43K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 8, 2024 (view filing) | Aug 7 | 1 day | Bozic CarmenEVP and CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.28K | $476.75 | −$1.09M | −8.9%23.3K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 2, 2024 (view filing) | Aug 1 | 1 day | Sachs Bruce IDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.29K | $508.00 | −$2.69M | −11.7%40.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 1, 2024 (view filing) | Jul 30 | 2 days | Kewalramani ReshmaCEO & President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.2K | $505.00 | −$7.68M | −14.3%91.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 25, 2024 (view filing) | Jul 24 | 1 day | Bozic CarmenEVP and CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.28K | $488.46 | −$1.11M | −8.2%25.5K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 24, 2024 (view filing) | Jul 22 | 2 days | Kewalramani ReshmaCEO & President | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.2K | $497.00 | −$7.56M | −12.5%106.2K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 12, 2024 (view filing) | Jul 10 | 2 days | Bozic CarmenEVP and CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.28K | $487.34 | −$1.11M | −7.6%27.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 28, 2024 (view filing) | Jun 26 | 2 days | Bozic CarmenEVP and CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.28K | $471.72 | −$1.08M | −7.0%30.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 13, 2024 (view filing) | Jun 12 | 1 day | Bozic CarmenEVP and CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.28K | $478.00 | −$1.09M | −6.6%32.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 13, 2024 (view filing) | Jun 12 | 1 day | Atkinson Edward Morrow IIIEVP, Chief Technical Ops. Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.29K | $478.00 | −$3.48M | −31.3%16.0K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2024 (view filing) | Jun 3 | 2 days | Wagner Charles F JrEVP & Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.25K | $460.00 | −$1.50M | −6.5%47.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 5, 2024 (view filing) | Jun 3 | 2 days | Tatsis OuraniaEVP, Chief Reg. & Quality Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.17K | $460.00 | −$1.00M | −4.2%49.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 3, 2024 (view filing) | May 30-31 | 4 days | Tatsis OuraniaEVP, Chief Reg. & Quality Off. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.60K | $441.99 | −$2.03M | −8.2%51.3K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 31, 2024 (view filing) | May 29 | 2 days | Bozic CarmenEVP and CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.28K | $445.56 | −$1.02M | −6.2%34.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 30, 2024 (view filing) | May 28 | 2 days | Wagner Charles F JrEVP & Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.25K | $454.79 | −$1.48M | −6.1%50.4K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
