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Trevi Therapeutics, Inc.

TRVI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001563880

In the last 90 days, Trevi Therapeutics, Inc. insiders filed 0 open-market purchases and 1 sale; 218 institutions reported holding it in 13F filings for Q2 2026, worth $2.76B in total; Viking Global Investors is the only superinvestor holding it.

13F holders, Q3 2025

Institutional positions in Trevi Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
164
+11 vs. Q2 2025
Shares held
129.3M
+14.7M (+12.8%) vs. Q2 2025
Total value
$1.18B
+$556.1M (+88.7%) vs. Q2 2025
New holders
35
65 more added
Sold out
24
42 more reduced

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TRVI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 164 institutions
Q1 2021: 19 institutionsQ2 2021: 17 institutionsQ3 2021: 18 institutionsQ4 2021: 17 institutionsQ1 2022: 23 institutionsQ2 2022: 32 institutionsQ3 2022: 40 institutionsQ4 2022: 37 institutionsQ1 2023: 36 institutionsQ2 2023: 53 institutionsQ3 2023: 55 institutionsQ4 2023: 63 institutionsQ1 2024: 80 institutionsQ2 2024: 77 institutionsQ3 2024: 93 institutionsQ4 2024: 110 institutionsQ1 2025: 137 institutionsQ2 2025: 154 institutionsQ3 2025: 164 institutionsQ4 2025: 184 institutionsQ1 2026: 198 institutionsQ2 2026: 218 institutions
Value heldQ3 2025: $1.18B
Q1 2021: $35.6MQ2 2021: $28.1MQ3 2021: $17.4MQ4 2021: $10.3MQ1 2022: $32.9MQ2 2022: $80.8MQ3 2022: $70.5MQ4 2022: $83.3MQ1 2023: $80.4MQ2 2023: $116.7MQ3 2023: $106.1MQ4 2023: $70.0MQ1 2024: $177.9MQ2 2024: $166.6MQ3 2024: $194.1MQ4 2024: $329.5MQ1 2025: $554.3MQ2 2025: $627.2MQ3 2025: $1.18BQ4 2025: $1.63BQ1 2026: $1.61BQ2 2026: $2.76B
Institutions holding TRVI and their total value by quarter
QuarterHoldersValue
Q2 2026218$2.76B
Q1 2026198$1.61B
Q4 2025184$1.63B
Q3 2025164$1.18B
Q2 2025154$627.2M
Q1 2025137$554.3M
Q4 2024110$329.5M
Q3 202493$194.1M
Q2 202477$166.6M
Q1 202480$177.9M
Q4 202363$70.0M
Q3 202355$106.1M
Q2 202353$116.7M
Q1 202336$80.4M
Q4 202237$83.3M
Q3 202240$70.5M
Q2 202232$80.8M
Q1 202223$32.9M
Q4 202117$10.3M
Q3 202118$17.4M
Q2 202117$28.1M
Q1 202119$35.6M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Trevi Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding TRVI in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Rosalind Advisors, Inc.100,000$915.0K0.33%−200,000−66.7%Reduced
LMR Partners LLP100,000$915.0K0.01%00.0%Unchanged
Woodline Partners LP100,282$917.6K0.00%−3,946,153−97.5%Reduced
Citadel Advisors LLC102,534$938.2K0.00%−1,216,732−92.2%Reduced
Sectoral Asset Management Inc105,950$969.4K0.60%−28,200−21.0%Reduced
Rhumbline Advisers115,022$1.05M0.00%+8,620+8.1%Added
UBS Asset Management Americas Inc116,477$1.07M0.00%+116,477New
Two Sigma Investments, LP119,930$1.10M0.00%−310−0.3%Reduced
State of Wisconsin Investment Board123,276$1.13M0.00%+6,031+5.1%Added
Swiss National Bank161,700$1.48M0.00%+161,700New
Royal Bank of Canada168,994$1.55M0.00%−655,186−79.5%Reduced
Nuveen, LLC183,329$1.68M0.00%+13,870+8.2%Added
Fred Alger Management, LLC191,045$1.75M0.01%+131,620+221.5%Added
Velan Capital Investment Management LP205,000$1.88M1.76%+205,000New
Barclays PLC216,885$1.98M0.00%−298,591−57.9%Reduced
Bank of New York Mellon Corp226,339$2.07M0.00%+60,074+36.1%Added
Renaissance Technologies LLC293,300$2.68M0.00%−196,000−40.1%Reduced
UBS Group AG298,612$2.73M0.00%−55,613−15.7%Reduced
StemPoint Capital LP350,710$3.21M0.65%+350,710New
Opaleye Management Inc.390,000$3.57M0.50%00.0%Unchanged
Invesco Ltd.483,070$4.42M0.00%+160,731+49.9%Added
Burkehill Global Management, LP525,000$4.80M0.27%00.0%Unchanged
EAM Investors, LLC549,479$4.97M0.57%+62,855+12.9%Added
Panagora Asset Management Inc570,468$5.22M0.02%+766+0.1%Added
Silverarc Capital Management, LLC588,789$5.39M0.78%+49,202+9.1%Added
Prudential Financial Inc602,654$5.51M0.01%+376,273+166.2%Added
Peregrine Capital Management LLC620,464$5.68M0.17%+620,464New
Balyasny Asset Management LLC626,462$5.73M0.01%−1,727,940−73.4%Reduced
Sphera Funds Management Ltd.643,957$5.89M1.40%−156,000−19.5%Reduced
Qube Research & Technologies Ltd651,679$5.96M0.01%+203,827+45.5%Added
Millennium Management LLC727,596$6.66M0.01%+570,352+362.7%Added
Northern Trust Corp736,930$6.74M0.00%+160,459+27.8%Added
Goldman Sachs Group Inc787,454$7.21M0.00%+488,409+163.3%Added
J. Goldman & Co LP792,806$7.25M0.27%−186,292−19.0%Reduced
Charles Schwab Investment Management Inc806,331$7.38M0.00%+580,396+256.9%Added
Point72 Asset Management, L.P.941,929$8.62M0.02%−786,747−45.5%Reduced
Flputnam Investment Management Co1,048,102$9.59M0.14%+961,150+1,105.4%Added
Pivotal bioVenture Partners Investment Advisor LLC1,256,782$11.5M6.65%+110,672+9.7%Added
Eventide Asset Management, LLC1,381,324$12.6M0.21%00.0%Unchanged
Raymond James Financial Inc1,411,037$12.9M0.00%+334,354+31.1%Added
Susquehanna International Group, LLP1,600,742$14.6M0.02%+1,473,157+1,154.6%Added
Bank of America Corp1,836,839$16.8M0.00%+739,342+67.4%Added
Artia Global Partners LP1,999,702$18.3M3.22%+687,862+52.4%Added
Acorn Capital Advisors, LLC2,144,844$19.6M9.96%00.0%Unchanged
Logos Global Management LP2,200,000$20.1M1.99%+1,350,000+158.8%Added
State Street Corp2,219,422$20.3M0.00%+386,502+21.1%Added
Geode Capital Management, LLC2,220,926$20.3M0.00%+434,081+24.3%Added
Siren, L.L.C.2,536,867$23.2M0.91%−1,401,926−35.6%Reduced
Affinity Asset Advisors, LLC2,800,000$25.6M2.38%+265,942+10.5%Added
Octagon Capital Advisors LP2,815,000$25.8M4.02%−857,000−23.3%Reduced
Wellington Management Group LLP3,253,888$29.8M0.01%+3,081,906+1,792.0%Added
FMR LLC3,299,891$30.2M0.00%+2,931,362+795.4%Added
OrbiMed Advisors LLC3,308,400$30.3M0.73%00.0%Unchanged
MPM Oncology Impact Management LP3,406,955$31.2M5.10%00.0%Unchanged
Alliancebernstein L.P.4,292,451$39.3M0.01%+11,096+0.3%Added
Morgan Stanley4,301,726$39.4M0.00%+3,277,715+320.1%Added
Marshall Wace, LLP4,841,751$44.3M0.05%+2,363,835+95.4%Added
Vivo Capital, LLC5,094,668$46.6M3.75%+606,765+13.5%Added
Viking Global Investors LPSuperinvestorViking Global Investors5,128,875$46.9M0.12%+3,585,875+232.4%Added
Vanguard Group Inc5,826,986$53.3M0.00%+510,295+9.6%Added
Rubric Capital Management LP8,531,860$78.1M1.05%00.0%Unchanged
BlackRock, Inc.9,901,053$90.6M0.00%+1,696,047+20.7%Added
Frazier Life Sciences Management, L.P.10,259,409$93.9M2.81%00.0%Unchanged
NEA Management Company, LLC13,222,228$121.0M6.64%00.0%Unchanged
Alyeska Investment Group, L.P.0$00.00%−650,000−100.0%Sold out
Acuta Capital Partners, LLC0$00.00%−493,735−100.0%Sold out
Ameriprise Financial Inc0$00.00%−154,854−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−86,830−100.0%Sold out
Polar Asset Management Partners Inc.0$00.00%−74,300−100.0%Sold out
XTX Topco Ltd0$00.00%−64,589−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−54,957−100.0%Sold out
Bridgeway Capital Management, LLC0$00.00%−44,981−100.0%Sold out
Omers Administration Corp0$00.00%−35,000−100.0%Sold out
Trexquant Investment LP0$00.00%−33,962−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−30,000−100.0%Sold out
Dauntless Investment Group, LLC0$00.00%−29,000−100.0%Sold out
Quadrature Capital Ltd0$00.00%−25,848−100.0%Sold out
Squarepoint Ops LLC0$00.00%−19,149−100.0%Sold out
Los Angeles Capital Management LLC0$00.00%−16,379−100.0%Sold out
O'Shaughnessy Asset Management, LLC0$00.00%−12,644−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−10,300−100.0%Sold out
Longaeva Partners L.P.0$00.00%−10,000−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−6,000−100.0%Sold out
Caitong International Asset Management Co., Ltd0$00.00%−1,689−100.0%Sold out
Point72 (DIFC) Ltd0$00.00%−461−100.0%Sold out
IFP Advisors, Inc0$00.00%0Sold out
Twin Peaks Wealth Advisors, LLC0$00.00%−2−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−1−100.0%Sold out
First Horizon Advisors, Inc.––––Not filed