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Tectonic Therapeutic, Inc.

TECX
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001681087

In the last 90 days, Tectonic Therapeutic, Inc. insiders filed 0 open-market purchases and 3 sales; 122 institutions reported holding it in 13F filings for Q2 2026, worth $479.9M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Tectonic Therapeutic, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
105
+7 vs. Q3 2025
Shares held
13.8M
+1.71M (+14.1%) vs. Q3 2025
Total value
$288.1M
+$98.2M (+51.7%) vs. Q3 2025
New holders
30
35 more added
Sold out
23
24 more reduced

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting TECX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 105 institutions
Q1 2021: 99 institutionsQ2 2021: 97 institutionsQ3 2021: 101 institutionsQ4 2021: 94 institutionsQ1 2022: 81 institutionsQ2 2022: 64 institutionsQ3 2022: 54 institutionsQ4 2022: 45 institutionsQ1 2023: 48 institutionsQ2 2023: 41 institutionsQ3 2023: 48 institutionsQ4 2023: 45 institutionsQ1 2024: 47 institutionsQ2 2024: 40 institutionsQ3 2024: 53 institutionsQ4 2024: 70 institutionsQ1 2025: 78 institutionsQ2 2025: 82 institutionsQ3 2025: 99 institutionsQ4 2025: 105 institutionsQ1 2026: 111 institutionsQ2 2026: 122 institutions
Value heldQ4 2025: $288.1M
Q1 2021: $423.5MQ2 2021: $287.7MQ3 2021: $166.5MQ4 2021: $134.9MQ1 2022: $38.8MQ2 2022: $23.8MQ3 2022: $15.7MQ4 2022: $14.8MQ1 2023: $22.8MQ2 2023: $18.9MQ3 2023: $39.9MQ4 2023: $32.2MQ1 2024: $35.2MQ2 2024: $88.1MQ3 2024: $217.4MQ4 2024: $354.9MQ1 2025: $198.8MQ2 2025: $240.7MQ3 2025: $189.9MQ4 2025: $288.1MQ1 2026: $426.8MQ2 2026: $479.9M
Institutions holding TECX and their total value by quarter
QuarterHoldersValue
Q2 2026122$479.9M
Q1 2026111$426.8M
Q4 2025105$288.1M
Q3 202599$189.9M
Q2 202582$240.7M
Q1 202578$198.8M
Q4 202470$354.9M
Q3 202453$217.4M
Q2 202440$88.1M
Q1 202447$35.2M
Q4 202345$32.2M
Q3 202348$39.9M
Q2 202341$18.9M
Q1 202348$22.8M
Q4 202245$14.8M
Q3 202254$15.7M
Q2 202264$23.8M
Q1 202281$38.8M
Q4 202194$134.9M
Q3 2021101$166.5M
Q2 202197$287.7M
Q1 202199$423.5M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Tectonic Therapeutic, Inc.; share changes are against Q3 2025.

Institutions holding TECX in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC2,807,442$58.6M0.00%+6610.0%Added
Standard Life Aberdeen plc1,141,824$23.8M0.04%+785,648+220.6%Added
Braidwell LP927,524$19.3M0.62%+190,657+25.9%Added
Baker Bros. Advisors LP903,400$18.8M0.11%+803,400+803.4%Added
BlackRock, Inc.854,363$17.8M0.00%+26,510+3.2%Added
5AM Venture Management, LLC606,660$12.7M3.98%+95,000+18.6%Added
Vanguard Group Inc599,898$12.5M0.00%+30,418+5.3%Added
OrbiMed Advisors LLC574,600$12.0M0.25%+574,600New
Point72 Asset Management, L.P.492,332$10.3M0.02%+70,577+16.7%Added
Vestal Point Capital, LP328,000$6.84M0.25%+328,000New
Citadel Advisors LLC317,617$6.63M0.00%+19,229+6.4%Added
Bollard Group LLC302,953$6.32M0.17%00.0%Unchanged
Millennium Management LLC300,820$6.28M0.00%+62,650+26.3%Added
Geode Capital Management, LLC263,560$5.50M0.00%−5,793−2.2%Reduced
Pale Fire Capital SE261,026$5.45M0.70%+1,300+0.5%Added
Prosight Management, LP235,000$4.90M1.01%−144,254−38.0%Reduced
Opaleye Management Inc.214,747$4.48M0.59%+214,747New
Kennedy Capital Management, Inc.209,225$4.36M0.09%+449+0.2%Added
State Street Corp209,125$4.36M0.00%+43,594+26.3%Added
Woodline Partners LP200,000$4.17M0.02%00.0%Unchanged
Squarepoint Ops LLC199,646$4.16M0.01%+134,211+205.1%Added
Susquehanna International Group, LLP151,713$3.16M0.00%+151,713New
Wells Fargo & Company120,411$2.51M0.00%+17,938+17.5%Added
D. E. Shaw & Co., Inc.120,250$2.51M0.00%+120,250New
ExodusPoint Capital Management, LP111,188$2.32M0.03%+98,171+754.2%Added
Morgan Stanley94,435$1.97M0.00%−10,298−9.8%Reduced
Goldman Sachs Group Inc92,703$1.93M0.00%−4,163−4.3%Reduced
Kotler Kevin80,000$1.67M1.23%+80,000New
Knott David M Jr74,000$1.54M0.71%00.0%Unchanged
Northern Trust Corp72,255$1.51M0.00%−10,976−13.2%Reduced
Connor, Clark & Lunn Investment Management Ltd.71,657$1.49M0.00%+27,772+63.3%Added
Gsa Capital Partners LLP63,276$1.32M0.11%+63,276New
Raymond James Financial Inc54,601$1.14M0.00%+2,670+5.1%Added
PFM Health Sciences, LP42,724$891.2K0.09%+42,724New
Sectoral Asset Management Inc42,255$881.4K0.71%−150,515−78.1%Reduced
Jump Financial, LLC39,500$824.0K0.01%+39,500New
Schonfeld Strategic Advisors LLC39,109$815.8K0.00%+39,109New
Wellington Management Group LLP37,379$779.7K0.00%+170.0%Added
Aldebaran Capital, LLC37,353$779.2K0.70%−1,149−3.0%Reduced
Charles Schwab Investment Management Inc32,461$677.1K0.00%+103+0.3%Added
UBS Group AG31,215$651.1K0.00%−35,245−53.0%Reduced
Marshall Wace, LLP30,918$644.9K0.00%+5,842+23.3%Added
ADAR1 Capital Management, LLC30,007$625.9K0.05%−26,000−46.4%Reduced
BIT Capital GmbH30,000$625.8K0.03%+30,000New
Monimus Capital Management, LP26,594$554.8K0.37%+2,700+11.3%Added
Bank of New York Mellon Corp25,858$539.4K0.00%−275−1.1%Reduced
Barclays PLC22,443$468.2K0.00%+4,467+24.8%Added
Aquatic Capital Management LLC22,262$464.4K0.01%+22,262New
Jane Street Group, LLC19,321$403.0K0.00%−9,399−32.7%Reduced
Quest Partners LLC18,187$379.4K0.02%+10,888+149.2%Added
Alps Advisors Inc15,369$320.6K0.00%+15,369New
SEI Investments Co15,251$318.1K0.00%+15,251New
Nuveen, LLC14,304$298.4K0.00%00.0%Unchanged
Rhumbline Advisers14,196$296.1K0.00%−1,797−11.2%Reduced
Virtus Investment Advisers, Inc.13,462$280.8K0.08%+8,391+165.5%Added
Palumbo Wealth Management LLC13,046$272.1K0.07%+13,046New
Marex Group plc12,501$260.8K0.00%+12,501New
Clarius Group, LLC10,130$211.3K0.01%00.0%Unchanged
Dimensional Fund Advisors LP10,075$210.2K0.00%+10,075New
Quadrature Capital Ltd10,014$208.9K0.00%−16,258−61.9%Reduced
Bank of America Corp9,225$192.4K0.00%+2,860+44.9%Added
Simplex Trading, LLC9,142$190.7K0.01%+8,374+1,090.4%Added
Deutsche Bank AG7,589$158.3K0.00%+7,589New
MetLife Investment Management6,724$140.3K0.00%00.0%Unchanged
Clearstead Advisors, LLC6,500$135.6K0.00%+5,000+333.3%Added
AlphaCentric Advisors LLC6,476$135.1K0.13%+6,476New
Canada Pension Plan Investment Board6,300$131.4K0.00%+6,300New
China Universal Asset Management Co., Ltd.6,050$126.2K0.01%−830−12.1%Reduced
JPMorgan Chase & Co5,779$120.5K0.00%−145−2.4%Reduced
Los Angeles Capital Management LLC6,410$112.8K0.00%+6,410New
Mirae Asset Global ETFs Holdings Ltd.5,079$105.9K0.00%−55−1.1%Reduced
New York State Common Retirement Fund5,000$104.3K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC5,000$104.3K0.00%+5,000New
BNP Paribas Arbitrage, SA2,819$58.8K0.00%+397+16.4%Added
Police & Firemen's Retirement System of New Jersey2,638$55.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.1,122$23.4K0.00%00.0%Unchanged
Legal & General Group Plc1,050$21.9K0.00%00.0%Unchanged
Citigroup Inc1,033$21.5K0.00%−125−10.8%Reduced
Russell Investments Group, Ltd.929$19.4K0.00%+19+2.1%Added
Mirae Asset Global Investments Co., Ltd.909$19.0K0.00%+186+25.7%Added
Tower Research Capital LLC (TRC)752$15.7K0.00%−713−48.7%Reduced
California State Teachers Retirement System676$14.1K0.00%−8−1.2%Reduced
HighMark Wealth Management LLC587$12.2K0.00%+587New
Group One Trading, L.P.541$11.3K0.00%+368+212.7%Added
Sterling Capital Management LLC537$11.2K0.00%−96−15.2%Reduced
Federation des caisses Desjardins du Quebec500$10.4K0.00%−500−50.0%Reduced
CWM, LLC466$10.0K0.00%+82+21.4%Added
Royal Bank of Canada521$10.0K0.00%+235+82.2%Added
Farther Finance Advisors, LLC373$7.78K0.00%+373New
GF Fund Management Co. Ltd.367$7.66K0.00%−36−8.9%Reduced
Amalgamated Bank345$7.00K0.00%−30−8.0%Reduced
UBS Asset Management Americas Inc173$3.61K0.00%+173New
Zurcher Kantonalbank (Zurich Cantonalbank)164$3.42K0.00%00.0%Unchanged
Vermillion & White Wealth Management Group, LLC107$2.23K0.00%00.0%Unchanged
Daiwa Securities Group Inc.80$2.00K0.00%00.0%Unchanged
Allworth Financial LP62$1.29K0.00%+62New
US Bancorp37$7720.00%00.0%Unchanged
Optima Capital LLC31$6470.00%+31New
GAMMA Investing LLC29$6050.00%+21+262.5%Added
Caldwell Trust Co20$4170.00%00.0%Unchanged