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Soleno Therapeutics Inc

SLNODelisted May 18, 2026
Industry
Pharmaceutical Preparations
SEC CIK
0001484565

Soleno Therapeutics Inc was delisted on May 18, 2026; its insiders filed their last Form 4 on May 18, 2026; 227 institutions reported holding it in 13F filings for Q1 2026, worth $2.09B in total; no superinvestor held it.

13F holders, Q4 2025

Institutional positions in Soleno Therapeutics Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
248
+14 vs. Q3 2025
Shares held
64.9M
−235.8K (−0.4%) vs. Q3 2025
Total value
$3.01B
−$1.40B (−31.7%) vs. Q3 2025
New holders
63
102 more added
Sold out
49
65 more reduced

6 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLNO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 248 institutions
Q1 2021: 63 institutionsQ2 2021: 47 institutionsQ3 2021: 39 institutionsQ4 2021: 39 institutionsQ1 2022: 41 institutionsQ2 2022: 40 institutionsQ3 2022: 22 institutionsQ4 2022: 26 institutionsQ1 2023: 21 institutionsQ2 2023: 23 institutionsQ3 2023: 54 institutionsQ4 2023: 76 institutionsQ1 2024: 98 institutionsQ2 2024: 114 institutionsQ3 2024: 142 institutionsQ4 2024: 166 institutionsQ1 2025: 217 institutionsQ2 2025: 234 institutionsQ3 2025: 240 institutionsQ4 2025: 248 institutionsQ1 2026: 227 institutionsQ2 2026: 0 institutions
Value heldQ4 2025: $3.01B
Q1 2021: $41.2MQ2 2021: $33.6MQ3 2021: $27.1MQ4 2021: $11.8MQ1 2022: $11.2MQ2 2022: $8.80MQ3 2022: $5.23MQ4 2022: $6.00MQ1 2023: $7.06MQ2 2023: $21.8MQ3 2023: $598.8MQ4 2023: $1.26BQ1 2024: $1.52BQ2 2024: $1.79BQ3 2024: $2.38BQ4 2024: $2.29BQ1 2025: $3.90BQ2 2025: $4.75BQ3 2025: $4.41BQ4 2025: $3.01BQ1 2026: $2.09BQ2 2026: $0
Institutions holding SLNO and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 2026227$2.09B
Q4 2025248$3.01B
Q3 2025240$4.41B
Q2 2025234$4.75B
Q1 2025217$3.90B
Q4 2024166$2.29B
Q3 2024142$2.38B
Q2 2024114$1.79B
Q1 202498$1.52B
Q4 202376$1.26B
Q3 202354$598.8M
Q2 202323$21.8M
Q1 202321$7.06M
Q4 202226$6.00M
Q3 202222$5.23M
Q2 202240$8.80M
Q1 202241$11.2M
Q4 202139$11.8M
Q3 202139$27.1M
Q2 202147$33.6M
Q1 202163$41.2M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Soleno Therapeutics Inc; share changes are against Q3 2025.

Institutions holding SLNO in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Jackson Creek Investment Advisors LLC13,760$637.0K0.19%−1,440−9.5%Reduced
Natixis13,840$640.8K0.00%+13,840New
Magnetar Financial LLC13,946$645.7K0.01%+13,946New
DnB Asset Management AS14,071$651.5K0.00%+7,710+121.2%Added
Oxford Asset Management LLP15,021$695.5K0.25%+15,021New
Man Group plc15,047$696.7K0.00%+3,555+30.9%Added
Handelsbanken Fonder AB15,400$713.0K0.00%+1,600+11.6%Added
State of New Jersey Common Pension Fund D15,418$713.9K0.00%−15,056−49.4%Reduced
Virginia Retirement Systems Et Al16,100$745.4K0.00%−1,600−9.0%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH16,774$776.6K0.00%+5,333+46.6%Added
FORA Capital, LLC16,979$786.1K0.10%+16,979New
Walleye Capital LLC16,983$786.3K0.00%+16,242+2,191.9%Added
Atom Investors LP17,550$812.6K0.06%+17,550New
Quantitative Investment Management, LLC17,581$814.0K0.08%+17,581New
Guggenheim Capital LLC18,181$841.8K0.01%+8,713+92.0%Added
Intech Investment Management LLC18,346$849.4K0.01%−4,241−18.8%Reduced
TD Asset Management Inc18,622$862.2K0.00%−95,130−83.6%Reduced
Envestnet Asset Management Inc18,975$878.5K0.00%+11,050+139.4%Added
AWM Investment Company, Inc.20,000$926.0K0.09%+20,000New
Teachers Retirement System of the State of Kentucky20,941$970.0K0.01%+7,040+50.6%Added
Zurcher Kantonalbank (Zurich Cantonalbank)21,075$975.8K0.00%+13,833+191.0%Added
Fox Run Management, L.L.C.21,785$1.01M0.16%+17,928+464.8%Added
MidWestOne Financial Group, Inc.21,817$1.01M0.11%+21,817New
Group One Trading, L.P.22,530$1.04M0.03%+14,134+168.3%Added
Virtu Financial LLC22,878$1.06M0.04%+22,878New
Prudential Financial Inc24,855$1.15M0.00%+12,695+104.4%Added
MetLife Investment Management25,761$1.19M0.01%+1,804+7.5%Added
Erste Asset Management GmbH25,600$1.22M0.01%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd26,685$1.24M0.03%+26,685New
Diadema Partners LP26,892$1.25M0.74%−150,438−84.8%Reduced
Mirae Asset Global ETFs Holdings Ltd.27,243$1.26M0.00%+3,112+12.9%Added
Fred Alger Management, LLC28,479$1.32M0.01%−140.0%Reduced
Aquatic Capital Management LLC28,572$1.32M0.04%+28,572New
Jefferies Financial Group Inc.29,304$1.36M0.01%+12,004+69.4%Added
Los Angeles Capital Management LLC19,669$1.36M0.00%−3,267−14.2%Reduced
F/M Investments LLC29,871$1.38M0.05%−25,859−46.4%Reduced
Diametric Capital, LP31,328$1.45M0.39%+23,867+319.9%Added
Nomura Asset Management International Inc.33,155$1.53M0.00%+33,155New
Citigroup Inc34,663$1.60M0.00%+11,740+51.2%Added
Militia Capital Partners, LP35,000$1.62M0.61%+35,000New
Profund Advisors LLC35,371$1.64M0.05%+15,532+78.3%Added
XTX Topco Ltd36,294$1.68M0.04%+36,294New
BNP PARIBAS ASSET MANAGEMENT Holding S.A.38,958$1.80M0.00%+38,559+9,663.9%Added
SG Americas Securities, LLC40,198$1.86M0.00%+25,412+171.9%Added
California State Teachers Retirement System40,717$1.89M0.00%+8,789+27.5%Added
Manufacturers Life Insurance Company, The41,186$1.91M0.00%−42,506−50.8%Reduced
Legal & General Group Plc41,788$1.93M0.00%+1,847+4.6%Added
ADAR1 Capital Management, LLC41,830$1.94M0.14%+16,600+65.8%Added
Caption Management, LLC42,100$1.95M0.09%−327,900−88.6%Reduced
Alliancebernstein L.P.42,290$1.96M0.00%00.0%Unchanged
Banque Pictet & Cie SA43,796$2.03M0.02%+43,796New
Boothbay Fund Management, LLC43,862$2.03M0.05%+9,632+28.1%Added
Winton Group Ltd44,200$2.05M0.07%+44,200New
Moody Aldrich Partners LLC46,306$2.14M0.40%−4,968−9.7%Reduced
Russell Investments Group, Ltd.46,678$2.16M0.00%−47,665−50.5%Reduced
Lazard Asset Management LLC48,445$2.24M0.00%−8,000−14.2%Reduced
Simplex Trading, LLC49,108$2.27M0.06%+23,999+95.6%Added
Wells Fargo & Company52,643$2.44M0.00%+22,163+72.7%Added
DV Trading LLC54,000$2.50M0.22%+54,000New
Jump Financial, LLC54,487$2.52M0.03%+54,487New
Rhumbline Advisers55,068$2.55M0.00%−4,792−8.0%Reduced
AQR Capital Management LLC58,752$2.72M0.00%+21,655+58.4%Added
KVP Capital Advisors, LP59,700$2.76M2.86%+59,700New
HealthInvest Partners AB62,735$2.90M0.93%+2,579+4.3%Added
SEI Investments Co67,330$3.12M0.00%−46,503−40.9%Reduced
Ikarian Capital, LLC68,823$3.19M0.41%+12,877+23.0%Added
National Philanthropic Trust69,545$3.22M0.03%+69,545New
UBS Asset Management Americas Inc72,360$3.35M0.00%+13,968+23.9%Added
State of Wisconsin Investment Board72,482$3.36M0.01%+32,290+80.3%Added
Mutual of America Capital Management LLC83,166$3.85M0.04%+4,333+5.5%Added
Swiss National Bank89,100$4.13M0.00%+12,400+16.2%Added
Rafferty Asset Management, LLC95,597$4.43M0.02%+3,122+3.4%Added
Nuveen, LLC100,622$4.66M0.00%+5,997+6.3%Added
JPMorgan Chase & Co115,517$5.35M0.00%−291,927−71.6%Reduced
Silverarc Capital Management, LLC117,485$5.44M0.79%+117,485New
Centiva Capital, LP118,804$5.50M0.33%+118,804New
Peregrine Capital Management LLC119,564$5.54M0.17%+26,559+28.6%Added
Frontier Capital Management Co LLC119,695$5.54M0.06%+1,351+1.1%Added
Nan Fung Trinity (HK) Ltd123,850$5.73M0.45%00.0%Unchanged
Royce & Associates LP129,043$5.97M0.06%+98,056+316.4%Added
Seven Fleet Capital Management LP130,079$6.02M4.08%+130,079New
Trexquant Investment LP132,912$6.15M0.05%+122,576+1,185.9%Added
HighVista Strategies LLC135,069$6.25M1.61%+116,369+622.3%Added
Eagle Health Investments LP135,100$6.26M1.37%+135,100New
Sphera Funds Management Ltd.136,314$6.31M1.32%+94,708+227.6%Added
Granahan Investment Management Inc137,592$6.37M0.27%+28,339+25.9%Added
Jane Street Group, LLC141,740$6.56M0.01%+141,740New
Deutsche Bank AG141,982$6.57M0.00%+5,205+3.8%Added
Capital World Investors145,522$6.74M0.00%−678,992−82.4%Reduced
Brevan Howard Capital Management LP147,800$6.84M0.13%+133,540+936.5%Added
Buckley Capital Advisors, LLC149,150$6.91M6.01%+149,150New
Barclays PLC157,685$7.30M0.00%−13,295−7.8%Reduced
Engineers Gate Manager LP168,005$7.78M0.09%+168,005New
Ally Bridge Group (NY) LLC168,029$7.78M12.35%−134,454−44.5%Reduced
UBS Group AG169,506$7.85M0.00%+11,198+7.1%Added
Clark Capital Management Group, Inc.180,250$8.35M0.05%+180,250New
New York State Common Retirement Fund185,317$8.58M0.01%+169,717+1,087.9%Added
Skandinaviska Enskilda Banken AB (publ)187,475$8.68M0.03%+64,736+52.7%Added
Bank of America Corp208,595$9.66M0.00%+46,497+28.7%Added
SummitTX Capital, L.P.211,727$9.80M0.30%+78,911+59.4%Added