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Sera Prognostics, Inc.

SERA
Exchange
Nasdaq
Industry
Services-Medical Laboratories
SEC CIK
0001534969

In the last 90 days, Sera Prognostics, Inc. insiders filed 0 open-market purchases and 5 sales; 47 institutions reported holding it in 13F filings for Q2 2026, worth $31.0M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Sera Prognostics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
57
−2 vs. Q3 2025
Shares held
17.6M
−503.1K (−2.8%) vs. Q3 2025
Total value
$52.1M
−$3.46M (−6.2%) vs. Q3 2025
New holders
6
14 more added
Sold out
8
14 more reduced

3 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SERA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 57 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 36 institutionsQ4 2021: 37 institutionsQ1 2022: 45 institutionsQ2 2022: 30 institutionsQ3 2022: 35 institutionsQ4 2022: 29 institutionsQ1 2023: 35 institutionsQ2 2023: 33 institutionsQ3 2023: 28 institutionsQ4 2023: 47 institutionsQ1 2024: 52 institutionsQ2 2024: 65 institutionsQ3 2024: 61 institutionsQ4 2024: 73 institutionsQ1 2025: 71 institutionsQ2 2025: 59 institutionsQ3 2025: 62 institutionsQ4 2025: 57 institutionsQ1 2026: 56 institutionsQ2 2026: 47 institutions
Value heldQ4 2025: $52.1M
Q1 2021: $0Q2 2021: $0Q3 2021: $96.1MQ4 2021: $63.8MQ1 2022: $36.6MQ2 2022: $14.2MQ3 2022: $13.9MQ4 2022: $8.86MQ1 2023: $36.5MQ2 2023: $31.4MQ3 2023: $16.5MQ4 2023: $66.8MQ1 2024: $131.1MQ2 2024: $98.2MQ3 2024: $140.3MQ4 2024: $147.2MQ1 2025: $74.4MQ2 2025: $51.5MQ3 2025: $55.6MQ4 2025: $52.1MQ1 2026: $40.5MQ2 2026: $31.0M
Institutions holding SERA and their total value by quarter
QuarterHoldersValue
Q2 202647$31.0M
Q1 202656$40.5M
Q4 202557$52.1M
Q3 202562$55.6M
Q2 202559$51.5M
Q1 202571$74.4M
Q4 202473$147.2M
Q3 202461$140.3M
Q2 202465$98.2M
Q1 202452$131.1M
Q4 202347$66.8M
Q3 202328$16.5M
Q2 202333$31.4M
Q1 202335$36.5M
Q4 202229$8.86M
Q3 202235$13.9M
Q2 202230$14.2M
Q1 202245$36.6M
Q4 202137$63.8M
Q3 202136$96.1M
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Sera Prognostics, Inc.; share changes are against Q3 2025.

Institutions holding SERA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Baker Bros. Advisors LP5,498,170$16.2M0.09%00.0%Unchanged
Whetstone Capital Advisors, LLC3,459,713$10.2M3.18%−172,658−4.8%Reduced
Standard Life Aberdeen plc2,279,699$6.73M0.01%00.0%Unchanged
Vivo Capital, LLC1,650,440$4.87M0.31%00.0%Unchanged
Vanguard Group Inc1,239,449$3.66M0.00%+22,259+1.8%Added
Citadel Advisors LLC707,614$2.09M0.00%+53,868+8.2%Added
Captrust Financial Advisors536,766$1.58M0.00%−65,570−10.9%Reduced
Geode Capital Management, LLC334,639$987.5K0.00%+3,524+1.1%Added
AWM Investment Company, Inc.207,382$611.8K0.06%00.0%Unchanged
BlackRock, Inc.186,751$550.9K0.00%+7,774+4.3%Added
State Street Corp124,792$368.1K0.00%00.0%Unchanged
Millennium Management LLC113,178$333.9K0.00%−14,109−11.1%Reduced
Gsa Capital Partners LLP107,235$316.0K0.03%+42,045+64.5%Added
CI Private Wealth, LLC100,000$290.0K0.00%00.0%Unchanged
Northern Trust Corp96,535$284.8K0.00%+8,052+9.1%Added
Morgan Stanley80,968$238.9K0.00%−3,046−3.6%Reduced
Bank of New York Mellon Corp75,267$222.0K0.00%00.0%Unchanged
Perigon Wealth Management, LLC72,685$214.4K0.00%00.0%Unchanged
Susquehanna International Group, LLP71,532$211.0K0.00%+49,160+219.7%Added
Jane Street Group, LLC68,826$203.0K0.00%+68,826New
Requisite Capital Management, LLC55,648$164.2K0.03%00.0%Unchanged
Twelve Points Wealth Management LLC43,388$160.1K0.04%00.0%Unchanged
Ballentine Partners, LLC49,664$146.5K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC45,705$134.8K0.00%00.0%Unchanged
HighTower Advisors, LLC42,234$124.6K0.00%00.0%Unchanged
Barclays PLC36,722$108.3K0.00%+26,726+267.4%Added
Squarepoint Ops LLC36,322$107.2K0.00%−56,741−61.0%Reduced
Qube Research & Technologies Ltd28,982$85.5K0.00%+4,899+20.3%Added
Goldman Sachs Group Inc28,599$84.4K0.00%−26,240−47.8%Reduced
Birch Hill Investment Advisors LLC27,293$80.5K0.00%00.0%Unchanged
UBS Group AG25,195$74.3K0.00%+672+2.7%Added
Cetera Investment Advisers25,000$73.8K0.00%+25,000New
Dimensional Fund Advisors LP22,934$67.5K0.00%+510+2.3%Added
Two Sigma Investments, LP21,964$64.8K0.00%−9,772−30.8%Reduced
Lido Advisors, LLC16,623$50.3K0.00%−5,541−25.0%Reduced
FMR LLC14,845$43.8K0.00%00.0%Unchanged
Wagner Wealth Management, LLC12,686$37.4K0.01%+286+2.3%Added
Riverview Capital Advisers, LLC12,669$37.4K0.01%−64−0.5%Reduced
Colony Group, LLC12,156$35.9K0.00%00.0%Unchanged
Charles Schwab Investment Management Inc12,085$35.7K0.00%−7−0.1%Reduced
Point72 Asset Management, L.P.11,403$33.6K0.00%+11,403New
Abel Hall, LLC11,037$32.6K0.01%00.0%Unchanged
Wealth Enhancement Advisory Services, LLC10,639$31.5K0.00%+10,639New
Deutsche Bank AG8,729$25.8K0.00%00.0%Unchanged
Geneos Wealth Management Inc.7,800$23.0K0.00%+3,300+73.3%Added
Bank of America Corp4,670$13.8K0.00%−774−14.2%Reduced
CWM, LLC1,006$3.00K0.00%−1−0.1%Reduced
Tower Research Capital LLC (TRC)945$2.79K0.00%+945New
Optiver Holding B.V.412$1.22K0.00%00.0%Unchanged
Torren Management, LLC389$1.15K0.00%+389New
Fortitude Family Office, LLC301$8880.00%00.0%Unchanged
BNP Paribas Arbitrage, SA236$6960.00%00.0%Unchanged
JPMorgan Chase & Co222$6550.00%00.0%Unchanged
Citigroup Inc200$5900.00%+195+3,900.0%Added
Nisa Investment Advisors, LLC129$3810.00%00.0%Unchanged
SBI Securities Co., Ltd.7$210.00%−1−12.5%Reduced
Royal Bank of Canada40$00.00%−2,173−98.2%Reduced
Sanders Morris Harris LLC0$00.00%−263,600−100.0%Sold out
Balentine LLC0$00.00%−84,475−100.0%Sold out
Cliftonlarsonallen Wealth Advisors, LLC0$00.00%−78,855−100.0%Sold out
CAPROCK Group, Inc.0$00.00%−33,523−100.0%Sold out
Pallas Capital Advisors LLC0$00.00%−13,711−100.0%Sold out
JustInvest LLC0$00.00%−12,561−100.0%Sold out
Advisory Services Network, LLC0$00.00%−19−100.0%Sold out
Avion Wealth0$00.00%−151−100.0%Sold out
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Cubist Systematic Strategies, LLC––––Not filed
Point72 (DIFC) Ltd––––Not filed