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Sana Biotechnology, Inc.

SANA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001770121

No open-market purchases or sales by Sana Biotechnology, Inc. insiders were filed in the last 90 days; 211 institutions reported holding it in 13F filings for Q2 2026, worth $644.7M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Sana Biotechnology, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
203
+27 vs. Q3 2025
Shares held
159.2M
−4.42M (−2.7%) vs. Q3 2025
Total value
$648.8M
+$67.0M (+11.5%) vs. Q3 2025
New holders
48
69 more added
Sold out
21
48 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SANA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 203 institutions
Q1 2021: 78 institutionsQ2 2021: 80 institutionsQ3 2021: 88 institutionsQ4 2021: 105 institutionsQ1 2022: 117 institutionsQ2 2022: 116 institutionsQ3 2022: 125 institutionsQ4 2022: 120 institutionsQ1 2023: 120 institutionsQ2 2023: 123 institutionsQ3 2023: 136 institutionsQ4 2023: 132 institutionsQ1 2024: 154 institutionsQ2 2024: 148 institutionsQ3 2024: 155 institutionsQ4 2024: 164 institutionsQ1 2025: 161 institutionsQ2 2025: 155 institutionsQ3 2025: 178 institutionsQ4 2025: 203 institutionsQ1 2026: 203 institutionsQ2 2026: 211 institutions
Value heldQ4 2025: $648.8M
Q1 2021: $3.10BQ2 2021: $1.93BQ3 2021: $2.48BQ4 2021: $1.73BQ1 2022: $985.8MQ2 2022: $807.5MQ3 2022: $769.7MQ4 2022: $507.0MQ1 2023: $427.4MQ2 2023: $804.1MQ3 2023: $493.5MQ4 2023: $508.1MQ1 2024: $1.46BQ2 2024: $810.3MQ3 2024: $638.8MQ4 2024: $257.4MQ1 2025: $250.6MQ2 2025: $396.9MQ3 2025: $581.8MQ4 2025: $648.8MQ1 2026: $473.1MQ2 2026: $644.7M
Institutions holding SANA and their total value by quarter
QuarterHoldersValue
Q2 2026211$644.7M
Q1 2026203$473.1M
Q4 2025203$648.8M
Q3 2025178$581.8M
Q2 2025155$396.9M
Q1 2025161$250.6M
Q4 2024164$257.4M
Q3 2024155$638.8M
Q2 2024148$810.3M
Q1 2024154$1.46B
Q4 2023132$508.1M
Q3 2023136$493.5M
Q2 2023123$804.1M
Q1 2023120$427.4M
Q4 2022120$507.0M
Q3 2022125$769.7M
Q2 2022116$807.5M
Q1 2022117$985.8M
Q4 2021105$1.73B
Q3 202188$2.48B
Q2 202180$1.93B
Q1 202178$3.10B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Sana Biotechnology, Inc.; share changes are against Q3 2025.

Institutions holding SANA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
FMR LLC37,430,284$152.3M0.01%−1,0810.0%Reduced
Flagship Pioneering Inc.25,001,856$101.8M31.40%00.0%Unchanged
BlackRock, Inc.14,223,527$57.9M0.00%+2,997,391+26.7%Added
Vanguard Group Inc10,455,195$42.6M0.00%+1,326,222+14.5%Added
Canada Pension Plan Investment Board10,242,100$41.7M0.03%+67,100+0.7%Added
State Street Corp8,054,841$32.8M0.00%+1,374,300+20.6%Added
Baillie Gifford & Co6,609,065$26.9M0.02%−4,827,438−42.2%Reduced
Geode Capital Management, LLC4,118,138$16.8M0.00%+694,606+20.3%Added
Marex Group plc3,732,780$15.2M0.16%−90,000−2.4%Reduced
Integral Health Asset Management, LLC3,000,000$12.2M0.62%+1,000,000+50.0%Added
Alphabet Inc.2,812,500$11.4M0.44%00.0%Unchanged
Renaissance Technologies LLC1,691,116$6.88M0.01%−301,384−15.1%Reduced
Balyasny Asset Management LLC1,679,130$6.83M0.01%+1,679,130New
Two Sigma Investments, LP1,579,705$6.43M0.01%+969,577+158.9%Added
Goldman Sachs Group Inc1,488,377$6.06M0.00%+806,285+118.2%Added
Northern Trust Corp1,407,699$5.73M0.00%+89,203+6.8%Added
Charles Schwab Investment Management Inc1,399,335$5.70M0.00%+126,772+10.0%Added
Woodline Partners LP1,317,641$5.36M0.02%−60,595−4.4%Reduced
Morgan Stanley1,285,045$5.23M0.00%+408,540+46.6%Added
Crestline Management, LP1,220,937$4.97M9.32%−600,000−33.0%Reduced
Bank of America Corp1,186,251$4.83M0.00%+268,609+29.3%Added
UBS Group AG1,182,958$4.81M0.00%−261,028−18.1%Reduced
AQR Capital Management LLC1,134,324$4.62M0.00%−47,458−4.0%Reduced
Omega Fund Management, LLC843,750$3.43M1.20%00.0%Unchanged
JPMorgan Chase & Co815,455$3.32M0.00%−1,319,989−61.8%Reduced
Price T Rowe Associates Inc766,487$3.12M0.00%+620,370+424.6%Added
Great Point Partners LLC700,000$2.85M0.92%00.0%Unchanged
ArrowMark Colorado Holdings LLC685,125$2.79M0.06%00.0%Unchanged
Jane Street Group, LLC668,884$2.72M0.00%+438,264+190.0%Added
CI Private Wealth, LLC638,367$2.60M0.00%−178,633−21.9%Reduced
Millennium Management LLC623,242$2.54M0.00%−996,758−61.5%Reduced
Deutsche Bank AG562,312$2.29M0.00%+18,999+3.5%Added
Invesco Ltd.561,835$2.29M0.00%+109,078+24.1%Added
Susquehanna International Group, LLP559,750$2.28M0.00%+46,229+9.0%Added
Barclays PLC509,889$2.08M0.00%−15,967−3.0%Reduced
Bank of New York Mellon Corp457,226$1.86M0.00%+51,565+12.7%Added
Swiss National Bank335,800$1.37M0.00%+73,500+28.0%Added
Squarepoint Ops LLC331,741$1.35M0.00%+109,419+49.2%Added
Nuveen, LLC325,212$1.32M0.00%+21,183+7.0%Added
Baker Bros. Advisors LP310,483$1.26M0.01%−1,720,466−84.7%Reduced
Private Advisor Group, LLC309,399$1.26M0.01%+309,399New
DekaBank Deutsche Girozentrale112,300$1.22M0.00%00.0%Unchanged
Rafferty Asset Management, LLC274,162$1.12M0.00%+6,177+2.3%Added
UBS Asset Management Americas Inc240,414$978.5K0.00%+99,767+70.9%Added
Ieq Capital, LLC236,692$963.3K0.00%−3,183−1.3%Reduced
Two Sigma Advisers, LP221,671$902.2K0.00%+221,671New
Wells Fargo & Company191,081$777.7K0.00%+84,715+79.6%Added
Rhumbline Advisers189,412$770.9K0.00%−6,294−3.2%Reduced
Alliancebernstein L.P.186,945$760.9K0.00%−9,800−5.0%Reduced
Susquehanna Portfolio Strategies, LLC167,503$681.7K0.01%00.0%Unchanged
Clarius Group, LLC166,065$675.9K0.04%−46,435−21.9%Reduced
California State Teachers Retirement System164,791$670.7K0.00%+36,115+28.1%Added
Voya Investment Management LLC163,536$665.6K0.00%+138,533+554.1%Added
Citigroup Inc154,764$629.9K0.00%+70,047+82.7%Added
Legal & General Group Plc151,018$614.6K0.00%+21,761+16.8%Added
Dimensional Fund Advisors LP133,078$541.6K0.00%−645,048−82.9%Reduced
Mirae Asset Global ETFs Holdings Ltd.130,291$530.4K0.00%−34,829−21.1%Reduced
State of Wisconsin Investment Board128,856$524.4K0.00%−69,323−35.0%Reduced
Palumbo Wealth Management LLC120,983$492.4K0.12%+9,695+8.7%Added
Virtu Financial LLC119,312$486.0K0.02%+78,088+189.4%Added
XTX Topco Ltd117,376$477.7K0.01%+10,581+9.9%Added
Profund Advisors LLC102,046$415.3K0.01%+44,326+76.8%Added
SG Americas Securities, LLC98,287$400.0K0.00%−1,971−2.0%Reduced
Gilder Gagnon Howe & Co LLC94,072$382.9K0.00%+2,533+2.8%Added
MetLife Investment Management93,126$379.0K0.00%+14,120+17.9%Added
HSBC Holdings PLC94,064$374.8K0.00%+15,836+20.2%Added
Manufacturers Life Insurance Company, The91,975$374.7K0.00%+44,458+93.6%Added
Marshall Wace, LLP88,788$361.4K0.00%+88,788New
CWM, LLC85,106$346.0K0.00%−90.0%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)82,393$335.3K0.00%+32,963+66.7%Added
SCS Capital Management LLC81,250$330.7K0.00%−70−0.1%Reduced
TD Asset Management Inc80,600$328.0K0.00%+80,600New
Virginia Retirement Systems Et Al77,350$314.8K0.00%+77,350New
Brevan Howard Capital Management LP70,607$287.4K0.01%+70,607New
Franklin Resources Inc69,401$282.5K0.00%−23,680−25.4%Reduced
VARCOV Co.64,907$264.2K0.10%+64,907New
GWM Advisors LLC64,399$262.1K0.00%−33,231−34.0%Reduced
D. E. Shaw & Co., Inc.60,900$247.9K0.00%+60,900New
Creative Planning60,899$247.9K0.00%+6,722+12.4%Added
Quinn Opportunity Partners LLC60,100$244.6K0.01%−60,000−50.0%Reduced
Algert Global LLC60,010$244.2K0.00%+60,010New
SRS Capital Advisors, Inc.59,028$240.2K0.01%−106,103−64.3%Reduced
Janus Henderson Group PLC58,189$236.5K0.00%00.0%Unchanged
BIT Capital GmbH58,000$236.1K0.01%+58,000New
Wealth Enhancement Advisory Services, LLC53,071$231.4K0.00%+199+0.4%Added
Schonfeld Strategic Advisors LLC55,842$227.3K0.00%+55,842New
Axq Capital, LP55,403$225.5K0.05%+37,177+204.0%Added
Modus Advisors, LLC55,000$223.8K0.06%+55,000New
Intech Investment Management LLC53,295$216.9K0.00%−19,356−26.6%Reduced
Virtus Investment Advisers, Inc.51,756$210.6K0.06%+6,958+15.5%Added
Arizona State Retirement System47,342$192.7K0.00%+7,359+18.4%Added
Police & Firemen's Retirement System of New Jersey44,245$180.1K0.00%+7,516+20.5%Added
China Universal Asset Management Co., Ltd.43,404$176.7K0.01%−1,943−4.3%Reduced
Cerity Partners LLC42,417$172.6K0.00%+279+0.7%Added
Colony Group, LLC42,156$171.6K0.00%+11,449+37.3%Added
ProShare Advisors LLC42,126$171.5K0.00%+10,096+31.5%Added
Pallas Capital Advisors LLC39,627$161.3K0.01%00.0%Unchanged
Raymond James Financial Inc39,273$159.8K0.00%+39,273New
New York State Common Retirement Fund38,609$157.1K0.00%00.0%Unchanged
Evoke Wealth, LLC38,569$157.0K0.00%+38,569New